GO:0007569

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Name cell aging
Categary Process
Go Slim No
Go Link GO:0007569
Unique Molecular Interactions 854
Total Molecular Interactions 1158
Total Single Events 11344
Pain Genes Associated 42

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell aging. They are ordered first by their pain relevance and then by number of times they were reported for cell aging. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
3 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
4 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
5 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
6 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
7 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
8 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
9 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
10 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
11 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
12 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
13 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
14 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
15 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22
16 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
17 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
18 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
19 INT139230 Icam1 Negative_regulation of Cmklr1 1 0.19 1.13 1.07
20 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06
21 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
22 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
23 INT154236 Binding of TBX3 and Ugt2b7 1 0.41 0.74 1
24 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
25 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
26 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
27 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
28 INT29366 Mnt Positive_regulation of Localization of Penk 1 0.01 0 0.96
29 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 0.21 0.98 0.95
30 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
31 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
32 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91
33 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
34 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
35 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
36 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
37 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
38 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
39 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
40 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
41 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
42 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
43 INT64067 Tp63 Negative_regulation of Localization of Gh1 1 0.08 0.07 0.76
44 INT250959 Binding of HLA-B and SOD1 1 0.05 0.75 0.75
45 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
46 INT296097 Acsm3 Negative_regulation of SOD1 1 0.01 1.3 0.72
47 INT186674 Binding of BGLAP and CYP27A1 1 0.01 1.91 0.71
48 INT40703 Mif Negative_regulation of Negative_regulation of POMC 1 0.24 0.49 0.7
49 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
50 INT64070 Tp63 Regulation of Ghrh 1 0.04 0.06 0.69
51 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
52 INT64068 Tp63 Regulation of Fdft1 1 0.00 0.06 0.69
53 INT70998 IL1B Regulation of Gene_expression of Icam1 1 0.44 0.95 0.67
54 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
55 INT334133 Acsm3 Positive_regulation of Icam1 1 0.23 1.61 0.66
56 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
57 INT66603 TFF2 Positive_regulation of Gene_expression of ICAM1 1 0.02 0 0.64
58 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
59 INT66601 WDR87 Positive_regulation of Gene_expression of ICAM1 1 0.00 0 0.63
60 INT66604 SARDH Positive_regulation of Gene_expression of ICAM1 1 0.01 0 0.63
61 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62
62 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
63 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61
64 INT164990 Mif Positive_regulation of Gene_expression of Grina 1 0.24 0.53 0.6
65 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57
66 INT66600 TFF2 Regulation of Positive_regulation of ICAM1 1 0.01 0 0.56
67 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
68 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
69 INT133049 TNF Positive_regulation of ICAM1 4 0.47 2.49 0.54
70 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
71 INT235390 HTR1A Regulation of BGLAP 1 0.03 0.23 0.51
72 INT137137 Binding of HIVEP1 and ICAM1 1 0.01 0.68 0.51
73 INT92997 Positive_regulation of SFTPA1 Positive_regulation of Binding of ICAM1 1 0.15 0.26 0.51
74 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
75 INT274625 OPN1MW Positive_regulation of SOD1 1 0.19 0.29 0.5
76 INT289464 Negative_regulation of IRF6 Positive_regulation of ICAM1 1 0.07 0.31 0.5
77 INT135586 CSF2 Regulation of ICAM1 1 0.13 1.3 0.49
78 INT71178 Binding of ITGB2 and Icam1 1 0.45 1.2 0.47
79 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
80 INT253997 Binding of Cd200r1 and Mif 1 0.03 1.02 0.46
81 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
82 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
83 INT235389 Binding of BGLAP and HTR1A 1 0.03 0.15 0.45
84 INT241914 SOD1 Positive_regulation of Ros1 1 0.00 0.76 0.44
85 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
86 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
87 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
88 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
89 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
90 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
91 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
92 INT250956 Positive_regulation of Binding of HLA-B and SOD1 1 0.07 0.38 0.38
93 INT249090 FOXL1 Regulation of Regulation of ICAM1 1 0.12 1.03 0.37
94 INT210952 Il1 Positive_regulation of Gene_expression of Icam1 1 0.01 0.86 0.37
95 INT296306 Binding of BGLAP and SPIN1 1 0.05 1.69 0.37
96 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
97 INT32212 POMC Regulation of Gene_expression of Mif 1 0.00 1.01 0.35
98 INT78893 TNF Regulation of Gene_expression of ICAM1 1 0.24 0.38 0.35
99 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
100 INT193492 Binding of Icam1 and Sele 1 0.06 1.05 0.34
101 INT72953 Mif Positive_regulation of Localization of Prl 1 0.42 0 0.34
102 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
103 INT130803 MC1R Regulation of Positive_regulation of Cdkn2a 1 0.17 0.82 0.34
104 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
105 INT353333 Positive_regulation of F2r Positive_regulation of Localization of Mif 1 0.46 0.26 0.32
106 INT311997 Regulation of STAM Regulation of BGLAP 1 0.00 0.61 0.32
107 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
108 INT72951 Mif Regulation of Prl 1 0.41 0 0.32
109 INT353334 F2r Positive_regulation of Mif 1 0.68 0 0.32
110 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
111 INT311991 STAM Regulation of BGLAP 1 0.00 0.61 0.31
112 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
113 INT303105 CAMK4 Positive_regulation of Hras1 1 0.04 0.16 0.31
114 INT353335 F2r Regulation of Positive_regulation of Mif 1 0.27 0.11 0.31
115 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
116 INT337085 Binding of Cxcr4 and Mif 1 0.21 1.89 0.3
117 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
118 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
119 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
120 INT353336 F2r Regulation of Localization of Mif 1 0.23 0.24 0.28
121 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
122 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
123 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
124 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
125 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
126 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
127 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
128 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
129 INT306942 Tnfsf12 Positive_regulation of Gene_expression of ICAM1 1 0.04 1.78 0.27
130 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
131 INT170258 Pecam1 Positive_regulation of Icam1 1 0.02 0.79 0.27
132 INT72952 Mif Regulation of Localization of Prl 1 0.28 0 0.27
133 INT254000 Regulation of Binding of Cxcr4 and Mif 1 0.29 0.56 0.27
134 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
135 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
136 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
137 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
138 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
139 INT353330 F2r Positive_regulation of Positive_regulation of Mif 1 0.46 0 0.26
140 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
141 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
142 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
143 INT239396 Atp7b Negative_regulation of Gene_expression of Icam1 1 0.07 1.69 0.26
144 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
145 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
146 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
147 INT128644 Binding of Icam1 and Selp 2 0.39 0.57 0.25
148 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
149 INT129220 IFNG Positive_regulation of ICAM1 1 0.09 0.1 0.25
150 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
151 INT179200 Binding of ICAM1 and IL8 1 0.03 1.02 0.25
152 INT129219 IFNG Positive_regulation of Gene_expression of ICAM1 1 0.13 0.1 0.25
153 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
154 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
155 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
156 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
157 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
158 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
159 INT284589 Binding of ICAM1 and Crp 1 0.00 1.08 0.22
160 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
161 INT207456 LGALS3 Negative_regulation of Gene_expression of BGLAP 1 0.13 0.5 0.22
162 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
163 INT141490 Negative_regulation of TNF Positive_regulation of ICAM1 1 0.29 0.58 0.21
164 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
165 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
166 INT139454 Binding of IGF2R and Icam1 1 0.00 0.4 0.21
167 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
168 INT60347 COL2A1 Positive_regulation of Gene_expression of Hras 1 0.05 0.92 0.2
169 INT158199 Negative_regulation of Binding of ICAM1 and AHSA1 1 0.15 0.3 0.2
170 INT158220 Positive_regulation of Binding of ICAM1 and TNFSF14 1 0.05 0.3 0.2
171 INT158223 Binding of ICAM1 and TNFSF14 1 0.04 0.3 0.2
172 INT305508 Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2
173 INT158218 Binding of ICAM1 and AHSA1 1 0.14 0.3 0.2
174 INT158227 Negative_regulation of Binding of ICAM1 and MAPK1 1 0.16 0.3 0.2
175 INT158236 Positive_regulation of Binding of ICAM1 and MAPK1 1 0.19 0.3 0.2
176 INT158226 Binding of ICAM1 and MAPK1 1 0.14 0.3 0.2
177 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
178 INT158213 Positive_regulation of Binding of ICAM1 and AHSA1 1 0.18 0.3 0.2
179 INT158229 Negative_regulation of Binding of ICAM1 and TNFSF14 1 0.05 0.3 0.2
180 INT125152 IL1B Regulation of Gene_expression of ICAM1 1 0.50 0.1 0.2
181 INT158215 TNFSF14 Positive_regulation of ICAM1 1 0.05 0.3 0.2
182 INT305511 Negative_regulation of Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2
183 INT214590 TIMP1 Regulation of ICAM1 1 0.10 0.29 0.19
184 INT28562 SOD1 Negative_regulation of Pacs1 1 0.03 2.63 0.19
185 INT214591 FOXC1 Regulation of ICAM1 1 0.05 0.29 0.19
186 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
187 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
188 INT214592 OAP Regulation of Gene_expression of ICAM1 1 0.02 0.77 0.19
189 INT251492 Binding of HSPD1 and SOD1 1 0.02 1.45 0.18
190 INT250949 Binding of KIR3DL2 and SOD1 1 0.24 0.55 0.18
191 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
192 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
193 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
194 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
195 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
196 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
197 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
198 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
199 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
200 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell aging. They are ordered first by their pain relevance and then by number of times they were reported in cell aging. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
2 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
3 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
4 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
5 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28
6 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55
7 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
8 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
9 INT116737 Localization of Mif 63 0.81 52.97 28.11
10 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54
11 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61
12 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
13 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
14 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72
15 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
16 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
17 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
18 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
19 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
20 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21
21 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
22 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52
23 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4
24 INT72949 Binding of Mif 31 0.46 23.12 11.65
25 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64
26 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
27 INT65713 Localization of ICAM1 42 0.81 39.55 11.49
28 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96
29 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81
30 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15
31 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9
32 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
33 INT80549 Binding of ICAM1 53 0.47 42.76 9.72
34 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5
35 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06
36 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
37 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
38 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
39 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26
40 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99
41 INT62944 Regulation of Icam1 33 0.47 23.52 7.94
42 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
43 INT48404 Regulation of Gene_expression of Icam1 21 0.62 15.1 7.81
44 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79
45 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
46 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
47 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
48 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
49 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91
50 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
51 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
52 INT517 Regulation of Mif 16 0.62 5.43 6.55
53 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
54 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
55 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
56 INT71727 Negative_regulation of Icam1 25 0.45 17.76 5.73
57 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
58 INT65712 Positive_regulation of Localization of ICAM1 14 0.70 16.72 5.5
59 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
60 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
61 INT60585 Regulation of TP53 59 0.59 54.55 5.21
62 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
63 INT4864 Regulation of BGLAP 22 0.34 10.8 5.07
64 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
65 INT137332 Positive_regulation of Gene_expression of Sod1 41 0.70 19.8 4.69
66 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
67 INT68260 Localization of BGLAP 34 0.78 16.04 4.63
68 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
69 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54
70 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
71 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
72 INT6513 Positive_regulation of Gene_expression of BGLAP 24 0.67 11.69 3.96
73 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8
74 INT70996 Positive_regulation of Positive_regulation of Icam1 8 0.60 6.02 3.74
75 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
76 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
77 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
78 INT12844 Binding of TP63 15 0.47 10.57 3.38
79 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
80 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
81 INT70994 Negative_regulation of Positive_regulation of Icam1 8 0.51 3.49 3.12
82 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
83 INT130226 Positive_regulation of Gene_expression of Mif 4 0.58 15.75 3.03
84 INT91341 Negative_regulation of Gene_expression of BGLAP 17 0.55 4.91 3.02
85 INT105884 Binding of Bcl2 19 0.35 15.67 3
86 INT8103 Binding of TP53 46 0.44 40.2 2.96
87 INT91342 Negative_regulation of Negative_regulation of BGLAP 2 0.55 1.39 2.88
88 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
89 INT203137 Binding of Mif 6 0.31 9.46 2.71
90 INT74216 Binding of Icam1 16 0.48 10.11 2.69
91 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
92 INT91899 Binding of Sod1 17 0.47 11.56 2.63
93 INT31989 Binding of SOD1 43 0.47 19.38 2.55
94 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
95 INT40748 Negative_regulation of Mif 6 0.56 8.33 2.46
96 INT135470 Transcription of Icam1 10 0.63 12.04 2.41
97 INT55952 Transcription of TP53 16 0.61 12.14 2.36
98 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
99 INT130230 Positive_regulation of Sod1 3 0.67 1.63 2.3
100 INT72865 Localization of Icam1 12 0.68 8.18 2.24
101 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
102 INT91340 Regulation of Localization of BGLAP 5 0.58 2.82 2.14
103 INT103304 Positive_regulation of Mif 6 0.48 8.66 2.05
104 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04
105 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
106 INT186893 Binding of BGLAP 10 0.37 6.19 2.02
107 INT96764 Positive_regulation of Gene_expression of SOD1 36 0.61 16.55 1.99
108 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
109 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
110 INT65855 Localization of TP53 18 0.76 17.08 1.89
111 INT69222 Positive_regulation of Sod1 15 0.61 8.19 1.87
112 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
113 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
114 INT145655 Transcription of Sod1 3 0.42 0.92 1.84
115 INT69221 Negative_regulation of Sod1 14 0.56 10.57 1.83
116 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
117 INT97062 Binding of PML 10 0.41 11.63 1.65
118 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
119 INT44149 Regulation of Gene_expression of Mif 6 0.54 2.45 1.63
120 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62
121 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
122 INT353326 Negative_regulation of Localization of Mif 1 0.45 1.28 1.59
123 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57
124 INT70993 Regulation of Positive_regulation of Icam1 2 0.45 1.22 1.57
125 INT27293 Regulation of SOD1 21 0.53 15.73 1.55
126 INT78816 Positive_regulation of Positive_regulation of ICAM1 9 0.68 8.36 1.55
127 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
128 INT91900 Localization of Sod1 12 0.77 6.62 1.51
129 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
130 INT117101 Gene_expression of Sod1 18 0.67 7.93 1.47
131 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
132 INT93005 Positive_regulation of Binding of ICAM1 5 0.68 4.55 1.42
133 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
134 INT145658 Negative_regulation of Transcription of Sod1 1 0.34 0.15 1.42
135 INT172953 Binding of Trp53 33 0.37 20.76 1.41
136 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
137 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
138 INT83464 Positive_regulation of Localization of Icam1 3 0.46 3.71 1.4
139 INT62824 Negative_regulation of Positive_regulation of ICAM1 7 0.53 2.94 1.39
140 INT145221 Binding of Tp53 10 0.37 8.59 1.37
141 INT63339 Transcription of ICAM1 6 0.69 3.92 1.37
142 INT54587 Positive_regulation of Hras1 12 0.27 5.54 1.3
143 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
144 INT253987 Regulation of Localization of Mif 3 0.43 1.65 1.27
145 INT41418 Regulation of Mif 2 0.40 3.86 1.24
146 INT314186 Gene_expression of Npm1 1 0.01 1.78 1.22
147 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21
148 INT117100 Positive_regulation of Gene_expression of Sod1 5 0.60 1.18 1.2
149 INT174156 Localization of Trp53 16 0.72 13.52 1.18
150 INT98595 Regulation of ILK 6 0.62 3.84 1.16
151 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
152 INT121368 Transcription of Mif 5 0.72 2.71 1.15
153 INT234422 Gene_expression of PML 14 0.75 15.93 1.14
154 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
155 INT278117 Negative_regulation of TP63 5 0.32 3.38 1.13
156 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
157 INT70021 Localization of BCL2 23 0.74 21.6 1.09
158 INT108997 Localization of Htt 28 0.77 3.76 1.07
159 INT159543 Localization of SOD1 29 0.75 8.62 1.06
160 INT42104 Regulation of Cdkn2a 4 0.44 5.67 1.06
161 INT102827 Protein_catabolism of Mif 1 0.33 0 1.06
162 INT129398 Negative_regulation of Gene_expression of SOD1 22 0.43 7.11 1.02
163 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
164 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
165 INT199009 Negative_regulation of Transcription of Icam1 4 0.38 3.81 0.95
166 INT73459 Transcription of Hras1 3 0.69 2.01 0.95
167 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
168 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
169 INT154886 Gene_expression of Htt 18 0.76 15.51 0.82
170 INT135836 Negative_regulation of Sod1 5 0.25 1.62 0.82
171 INT353328 Regulation of Positive_regulation of Mif 1 0.40 0.89 0.81
172 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
173 INT70019 Binding of BCL2 25 0.47 17.55 0.79
174 INT147433 Gene_expression of BRCA2 7 0.62 7.02 0.79
175 INT144429 Positive_regulation of Cdkn2a 7 0.58 4.05 0.78
176 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
177 INT129115 Negative_regulation of Cdkn2a 16 0.50 17.03 0.76
178 INT44293 Regulation of TP63 6 0.24 2.88 0.76
179 INT312011 Negative_regulation of Binding of BGLAP 1 0.11 1.04 0.76
180 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
181 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
182 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
183 INT258791 Positive_regulation of CDK1 14 0.45 5.73 0.74
184 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
185 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
186 INT129630 Regulation of Sod1 6 0.44 4.94 0.73
187 INT2108 Localization of Mif 5 0.77 2.7 0.73
188 INT262726 Localization of PML 6 0.57 7.13 0.72
189 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
190 INT36887 Regulation of Hras 2 0.44 0.76 0.72
191 INT127432 Gene_expression of Nup62 20 0.71 11.01 0.71
192 INT28561 Regulation of Gene_expression of SOD1 9 0.61 2.83 0.71
193 INT66607 Regulation of Positive_regulation of ICAM1 3 0.42 2.81 0.71
194 INT62273 Gene_expression of CDK1 19 0.75 8.43 0.68
195 INT32209 Regulation of Gene_expression of Mif 3 0.59 3.41 0.66
196 INT130229 Regulation of Negative_regulation of Mif 1 0.39 1.36 0.66
197 INT353322 Negative_regulation of Positive_regulation of Mif 1 0.38 0.35 0.66
198 INT164957 Regulation of Gene_expression of Hras1 8 0.04 4.4 0.64
199 INT44148 Negative_regulation of Gene_expression of Mif 6 0.41 0.95 0.64
200 INT60343 Gene_expression of Hras 6 0.75 2.3 0.64
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