GO:0007586

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Name digestion
Categary Process
Go Slim No
Go Link GO:0007586
Unique Molecular Interactions 354
Total Molecular Interactions 428
Total Single Events 3624
Pain Genes Associated 37

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for digestion. They are ordered first by their pain relevance and then by number of times they were reported for digestion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT36536 PRSS1 Positive_regulation of PENK 1 0.24 0.86 4.39
2 INT36535 PRSS1 Positive_regulation of Regulation of PENK 1 0.23 0.54 3.06
3 INT23280 PRSS1 Positive_regulation of Penk 1 0.05 1.53 2.74
4 INT33756 Akr1d1 Positive_regulation of Npr1 3 0.01 0 2.05
5 INT82867 Cck Regulation of Localization of Pgc 1 0.05 0 1.83
6 INT116092 TFF2 Positive_regulation of NFKB1 1 0.17 0.06 1.77
7 INT33759 Hmmr Positive_regulation of Akr1d1 1 0.00 0 1.58
8 INT7791 Akr1d1 Regulation of Nts 1 0.03 0 1.58
9 INT7796 Akr1d1 Regulation of Npy 1 0.03 0 1.57
10 INT7797 Akr1d1 Regulation of Sst 1 0.02 0 1.54
11 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
12 INT116094 Binding of TACR1 and TFF2 1 0.06 0 1.47
13 INT104975 MITF Regulation of Transcription of PRSS1 1 0.68 0.35 1.46
14 INT12691 SST Negative_regulation of Localization of POMC 3 0.24 1.24 1.45
15 INT224404 Binding of GYPC and PYY 1 0.04 1.48 1.42
16 INT26812 SST Regulation of Localization of OXT 1 0.40 0.57 1.37
17 INT96707 Ntf3 Positive_regulation of Localization of SST 1 0.01 0 1.3
18 INT96708 Bdnf Positive_regulation of Localization of SST 1 0.01 0 1.3
19 INT107858 PRSS1 Positive_regulation of F2RL1 6 0.12 4.23 1.29
20 INT81097 Akr1d1 Regulation of Localization of Abat 1 0.00 0 1.2
21 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
22 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
23 INT13203 Oprd1 Negative_regulation of Akr1d1 1 0.01 0 1.18
24 INT203016 CCK Positive_regulation of Localization of PYY 3 0.68 1.19 1.17
25 INT13204 Binding of Npr1 and Akr1d1 1 0.00 0 1.14
26 INT60133 MME Negative_regulation of SST 1 0.10 0 1.12
27 INT133497 Binding of Oprm1 and Cckbr 1 0.03 0 1.1
28 INT282712 Binding of MUC5AC and Csf2 1 0.01 2.63 1.07
29 INT30575 SST Negative_regulation of Localization of Pomc 1 0.00 0.71 1.06
30 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04
31 INT40715 Binding of SST and Penk 1 0.10 0 1.02
32 INT95791 Binding of SSTR1 and GRHL3 1 0.38 0.57 0.99
33 INT97721 Akr1d1 Regulation of Gene_expression of Penk 1 0.00 0 0.98
34 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
35 INT11392 Cck Positive_regulation of Cckbr 1 0.52 0 0.96
36 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
37 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
38 INT80601 Akr1d1 Regulation of Positive_regulation of Fos 1 0.06 0 0.94
39 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
40 INT136172 NPY Negative_regulation of Positive_regulation of Drd1a 1 0.21 0 0.91
41 INT7799 Akr1d1 Regulation of Positive_regulation of Ptgdr 1 0.01 0 0.86
42 INT261461 Positive_regulation of Akr1d1 Regulation of Sftpd 1 0.01 0 0.86
43 INT2881 SST Negative_regulation of Positive_regulation of CCK 1 0.32 0.1 0.84
44 INT2880 SST Negative_regulation of CCK 1 0.32 0.1 0.84
45 INT84087 B3GAT1 Positive_regulation of Localization of SST 1 0.06 0 0.83
46 INT261458 Akr1d1 Regulation of Sftpd 1 0.01 0 0.82
47 INT303656 SST Negative_regulation of Localization of GAST 1 0.12 1.45 0.82
48 INT54260 SST Regulation of GH1 1 0.18 0.06 0.81
49 INT78348 Binding of GALR1 and GAL 4 0.41 1.47 0.8
50 INT117604 AKR1C1 Negative_regulation of Positive_regulation of Mpo 1 0.00 1.45 0.78
51 INT261447 Sftpd Positive_regulation of Akr1d1 1 0.01 0 0.77
52 INT54802 SST Negative_regulation of Localization of Gh 1 0.01 0 0.75
53 INT54801 SST Negative_regulation of Positive_regulation of Gh 1 0.01 0 0.75
54 INT41166 Gtf3a Regulation of Localization of SST 1 0.00 0.16 0.74
55 INT144453 Binding of GPM6A and SSTR2 1 0.02 0 0.74
56 INT82039 Akr1d1 Positive_regulation of Phosphorylation of Ppp1r1b 1 0.02 0 0.74
57 INT41164 Binding of INS and SST 1 0.07 0.14 0.73
58 INT30904 SST Negative_regulation of Localization of Gast 2 0.08 0.49 0.71
59 INT73824 TFF2 Positive_regulation of Localization of IL1B 1 0.02 0.56 0.71
60 INT73823 TFF2 Positive_regulation of Gene_expression of VCAM1 1 0.04 0.59 0.69
61 INT52570 HTR1D Negative_regulation of Localization of SST 1 0.46 0.07 0.67
62 INT84213 Cck Regulation of Cckbr 1 0.41 0 0.67
63 INT7418 Calca Positive_regulation of Localization of SST 1 0.04 0.19 0.67
64 INT114217 Binding of VIPR1 and Trpv1 1 0.03 0 0.66
65 INT7792 Akr1d1 Regulation of Gene_expression of Npy 1 0.02 0 0.65
66 INT261453 Binding of Akr1d1 and Ptgdr 1 0.00 0.56 0.65
67 INT82038 Positive_regulation of Akr1d1 Positive_regulation of Phosphorylation of Ppp1r1b 1 0.02 0 0.64
68 INT63655 Binding of NPY and TAC1 1 0.39 0.17 0.64
69 INT89757 SST Regulation of Regulation of CCK 1 0.21 0.37 0.64
70 INT66603 TFF2 Positive_regulation of Gene_expression of ICAM1 1 0.02 0 0.64
71 INT66602 TFF2 Positive_regulation of Gene_expression of IL8 1 0.01 0 0.63
72 INT30902 GCG Positive_regulation of Localization of SST 1 0.11 0.05 0.62
73 INT15731 SST Regulation of Gh 1 0.04 0 0.62
74 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61
75 INT26997 SST Positive_regulation of Negative_regulation of Gnrhr 1 0.00 0.08 0.59
76 INT41935 SST Negative_regulation of Localization of Nts 1 0.03 0 0.59
77 INT35862 PRSS1 Regulation of Localization of GBE1 1 0.00 0.35 0.59
78 INT63161 Akr1d1 Regulation of Gene_expression of Pdyn 1 0.01 0 0.59
79 INT91393 Crh Positive_regulation of SST 1 0.01 0.73 0.58
80 INT303652 Binding of SST and SSTR2 1 0.26 0.46 0.57
81 INT201512 Binding of PRSS1 and hcp 1 0.09 1.9 0.57
82 INT18405 GHRH Positive_regulation of Regulation of SST 1 0.56 0 0.57
83 INT303654 Binding of SST and SSTR5 1 0.22 0.46 0.57
84 INT66600 TFF2 Regulation of Positive_regulation of ICAM1 1 0.01 0 0.56
85 INT69826 Binding of SST and TBC1D4 1 0.08 1.49 0.56
86 INT82868 Cck Regulation of Pgc 1 0.05 0 0.55
87 INT316546 Binding of GH1 and SST 2 0.03 0.55 0.54
88 INT303653 Binding of DRD2 and SST 1 0.18 0.45 0.54
89 INT113627 Binding of NPY and RHD 1 0.04 0 0.54
90 INT30959 Ghrh Positive_regulation of Localization of SST 1 0.01 0 0.54
91 INT54485 Positive_regulation of Akr1d1 Positive_regulation of Gene_expression of Rabep2 1 0.00 0 0.53
92 INT282713 Binding of MUC5AC and Mmp9 1 0.02 1.27 0.52
93 INT20580 Drd2 Regulation of Akr1d1 1 0.02 0.26 0.51
94 INT132443 Binding of MEP1A and EFHC1 1 0.44 1.19 0.5
95 INT97483 ADCYAP1 Positive_regulation of Localization of SST 1 0.04 0 0.5
96 INT229127 SPINK1 Positive_regulation of PRSS1 1 0.53 1.59 0.48
97 INT144110 PRSS1 Positive_regulation of Gene_expression of IL8 1 0.21 1.38 0.48
98 INT7291 Akr1d1 Regulation of Regulation of Penk 1 0.01 0 0.48
99 INT229128 Binding of CP and PRSS1 1 0.14 0.77 0.47
100 INT195192 Akr1d1 Regulation of Msn 1 0.01 0.34 0.47
101 INT26009 Cck Negative_regulation of Positive_regulation of Cckbr 1 0.26 0 0.47
102 INT71839 Chrm3 Positive_regulation of Qrfp 1 0.09 0 0.47
103 INT96709 Ntf3 Regulation of Localization of SST 1 0.01 0 0.46
104 INT7656 Binding of SST and Gs 1 0.02 0.27 0.46
105 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45
106 INT303651 Binding of SSTR2 and SSTR5 1 0.24 0.23 0.45
107 INT341624 Binding of CFTR and PRSS1 1 0.39 1.01 0.45
108 INT30219 Nts Regulation of Localization of SST 1 0.01 0 0.45
109 INT55261 Cck Regulation of Positive_regulation of Cckbr 1 0.18 0 0.45
110 INT55264 Pigt Regulation of Positive_regulation of Cckbr 1 0.03 0 0.44
111 INT91087 SST Positive_regulation of Positive_regulation of Prkcg 1 0.29 0.05 0.43
112 INT203017 Binding of CCK and PYY 1 0.38 0.62 0.43
113 INT327562 Binding of MCS and AKR1B10 1 0.00 0.5 0.41
114 INT72348 Mbp Positive_regulation of Localization of PRSS1 1 0.01 0.22 0.41
115 INT46328 Sct Regulation of PPY 1 0.30 0.49 0.41
116 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41
117 INT72345 MBP Positive_regulation of Localization of PRSS1 1 0.00 0.22 0.41
118 INT124405 Binding of SST and SSTR1 1 0.01 0.5 0.41
119 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4
120 INT37249 CRH Positive_regulation of PPY 1 0.04 0.34 0.39
121 INT245503 SST Regulation of Gene_expression of CSF2 1 0.06 0.67 0.39
122 INT122188 Binding of Crh and Ucn2 2 0.22 0.29 0.38
123 INT105772 SST Negative_regulation of Localization of GH1 1 0.10 0.54 0.38
124 INT40728 SST Regulation of IRG1 1 0.11 0.36 0.38
125 INT105770 SST Negative_regulation of Localization of TRH 1 0.17 0.54 0.38
126 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37
127 INT122189 Binding of Crhr1 and Ucn2 2 0.08 0.27 0.36
128 INT7415 Calca Positive_regulation of Positive_regulation of SST 1 0.05 0.1 0.34
129 INT261462 Akr1d1 Positive_regulation of Hrasls 1 0.00 0.3 0.33
130 INT171678 PPY Regulation of CISD1 1 0.00 0.33 0.33
131 INT57807 Binding of SST and SCG2 1 0.23 0 0.33
132 INT171679 PPY Regulation of PRKCA 1 0.08 0.33 0.33
133 INT190290 Binding of CXCL12 and VIPR1 1 0.06 0 0.33
134 INT35861 PRSS1 Regulation of Localization of CCK 1 0.26 0.17 0.33
135 INT171680 PPY Regulation of MAPK4 1 0.02 0.33 0.33
136 INT122168 AKR1C1 Regulation of PPARG 1 0.12 0.25 0.31
137 INT168948 Binding of CCK and CCKAR 1 0.23 0 0.3
138 INT35859 PRSS1 Regulation of Regulation of CCK 1 0.13 0.18 0.3
139 INT35863 PRSS1 Regulation of Positive_regulation of CCK 1 0.22 0.18 0.3
140 INT156087 Binding of AKR1C3 and Akr1c1 1 0.05 0.31 0.3
141 INT35858 PRSS1 Regulation of Positive_regulation of SCT 1 0.17 0.18 0.3
142 INT156083 Binding of AKR1C2 and AKR1C3 1 0.05 0.31 0.3
143 INT118239 Binding of CCKAR and CYP2B6 1 0.32 0.19 0.29
144 INT207823 SSTR2 Negative_regulation of Localization of GCG 1 0.06 0 0.29
145 INT60448 NPY Positive_regulation of Gnrhr 1 0.01 0 0.29
146 INT203015 CCK Regulation of Localization of PYY 1 0.24 0.61 0.28
147 INT89900 SST Positive_regulation of Localization of GH1 1 0.14 0 0.28
148 INT89907 SST Positive_regulation of Localization of POMC 1 0.44 0 0.28
149 INT7404 CALCA Positive_regulation of SST 1 0.00 0.08 0.28
150 INT67193 IL8 Regulation of Localization of SST 1 0.00 0.66 0.28
151 INT233785 Binding of SCT and VIPR1 1 0.08 0 0.27
152 INT51858 Akr1d1 Positive_regulation of Phosphorylation of Creb1 1 0.01 0 0.27
153 INT280832 Binding of Crh and Ucn3 1 0.16 0.07 0.27
154 INT224406 INS Regulation of Localization of PYY 1 0.11 0.27 0.27
155 INT101630 Binding of OPRM1 and SST 1 0.34 0 0.26
156 INT167881 Ctrb1 Regulation of Gene_expression of PRSS2 1 0.10 1.81 0.26
157 INT64290 Akr1d1 Regulation of Penk 1 0.00 0 0.26
158 INT108904 Binding of NPY and Npffr2 1 0.36 0.08 0.26
159 INT167880 Pnliprp1 Regulation of Gene_expression of PRSS2 1 0.13 1.81 0.26
160 INT115514 Binding of PRSS1 and KRT79 1 0.02 1.19 0.26
161 INT280811 Binding of Crhr1 and Ucn3 1 0.08 0.05 0.25
162 INT51045 Adarb1 Regulation of Localization of Pgc 1 0.01 0 0.25
163 INT137237 SST Regulation of SHOX 1 0.06 0.25 0.25
164 INT239087 Binding of SST and Negative_regulation of Localization of GH1 1 0.19 0.36 0.24
165 INT229129 SPINK1 Negative_regulation of PRSS1 1 0.49 0.79 0.24
166 INT72202 GH1 Regulation of SST 1 0.28 0 0.24
167 INT64291 Akr1d1 Regulation of Slc3a1 1 0.01 0 0.23
168 INT20030 Negative_regulation of SST Positive_regulation of Ghrh 1 0.01 0.16 0.23
169 INT64289 Slc3a1 Regulation of Akr1d1 1 0.01 0 0.23
170 INT20031 Negative_regulation of SST Positive_regulation of Gh 1 0.00 0.16 0.23
171 INT61346 Positive_regulation of YY1 Positive_regulation of Localization of SST 1 0.54 0 0.22
172 INT224904 Binding of GALR2 and GAL 1 0.16 0.37 0.22
173 INT143909 SST Regulation of Gnrhr 1 0.00 0 0.22
174 INT318189 MUC5AC Regulation of Gene_expression of VEGFA 1 0.21 1.17 0.22
175 INT355503 Positive_regulation of SCN10A Positive_regulation of Localization of NPY 1 0.17 1.32 0.22
176 INT78349 Binding of GALR1 and TUBB 1 0.39 0 0.21
177 INT92205 Crh Positive_regulation of Localization of SST 1 0.30 0.87 0.21
178 INT197811 Binding of SMS and SST 1 0.00 0.98 0.21
179 INT90772 Binding of AKR1C4 and AKR1C1 1 0.39 0.08 0.2
180 INT46285 SCT Positive_regulation of PRSS1 1 0.16 0.1 0.19
181 INT46283 CCK Positive_regulation of PRSS1 1 0.06 0.1 0.19
182 INT326940 Chrm3 Positive_regulation of Nalcn 1 0.06 0.21 0.19
183 INT191241 SST Regulation of SAE1 1 0.05 0.89 0.18
184 INT115510 Binding of PRSS1 and PRSS2 1 0.41 0.8 0.18
185 INT318211 MUC5AC Positive_regulation of Muc4 1 0.17 1.12 0.17
186 INT318188 MUC5AC Positive_regulation of MUC1 1 0.16 1.12 0.17
187 INT12693 SST Negative_regulation of Localization of EPO 1 0.08 0 0.17
188 INT278609 PPARA Positive_regulation of Gene_expression of SULT2A1 1 0.33 0 0.17
189 INT261460 Binding of Sftpd and Akr1d1 1 0.01 0.43 0.16
190 INT303659 SSTR2 Negative_regulation of Gene_expression of SST 1 0.30 0.94 0.16
191 INT303657 Gene_expression of SSTR2 Negative_regulation of Gene_expression of SST 1 0.30 0.94 0.16
192 INT35860 PRSS1 Regulation of Localization of SCT 1 0.10 0.08 0.16
193 INT354114 Binding of CALR and SST 1 0.01 0.1 0.16
194 INT303744 Binding of Chrm3 and Ins1 1 0.04 1.03 0.15
195 INT199129 Ctsb Positive_regulation of PRSS1 1 0.01 0.9 0.15
196 INT278614 NR1I2 Regulation of Gene_expression of SULT2A1 1 0.11 0.11 0.15
197 INT303745 Positive_regulation of Binding of Chrm3 and Ins1 1 0.05 1.04 0.15
198 INT303747 Binding of Chrm3 and Chrm1 1 0.03 1.02 0.15
199 INT172256 Binding of NMU and GPR87 1 0.31 0 0.14
200 INT106995 PRSS1 Positive_regulation of SPG21 1 0.04 0.29 0.14

Single Events

The table below shows the top 100 pain related interactions that have been reported for digestion. They are ordered first by their pain relevance and then by number of times they were reported in digestion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT397 Localization of SST 232 0.81 58.05 101.19
2 INT8347 Gene_expression of SST 181 0.78 104.59 65.45
3 INT5118 Regulation of SST 97 0.62 34.35 51.74
4 INT692 Negative_regulation of SST 72 0.59 28.68 34.52
5 INT691 Binding of SST 67 0.48 24.66 32.67
6 INT7787 Positive_regulation of Akr1d1 52 0.66 3.55 31.71
7 INT7412 Positive_regulation of SST 71 0.70 24.44 29.48
8 INT15458 Gene_expression of NPY 50 0.76 22.67 23.03
9 INT20575 Gene_expression of Akr1d1 48 0.57 6.2 22.5
10 INT693 Negative_regulation of Localization of SST 46 0.59 8.57 21.75
11 INT7920 Binding of Akr1d1 26 0.27 3.64 19.73
12 INT12243 Positive_regulation of PRSS1 91 0.70 52.87 19.48
13 INT11243 Localization of NPY 33 0.78 11.18 19.24
14 INT34569 Regulation of Akr1d1 26 0.24 3.06 18.37
15 INT7414 Regulation of Localization of SST 31 0.60 4.85 17.46
16 INT36554 Gene_expression of PRSS1 70 0.78 50.25 15.33
17 INT11034 Negative_regulation of Akr1d1 23 0.18 3.43 14.84
18 INT7413 Positive_regulation of Localization of SST 37 0.69 5.64 13.94
19 INT64563 Gene_expression of UGT1A1 27 0.75 3.31 13.43
20 INT15238 Positive_regulation of NPY 24 0.67 11.86 11.26
21 INT22447 Gene_expression of TFF2 17 0.77 3.4 11.08
22 INT12240 Negative_regulation of PRSS1 46 0.57 29.5 10.77
23 INT1108 Gene_expression of PPY 58 0.75 36.57 10.76
24 INT65009 Gene_expression of HTR3A 29 0.75 8.51 10.59
25 INT3180 Positive_regulation of PPY 39 0.63 25.57 10.15
26 INT203020 Positive_regulation of PYY 37 0.68 18.81 9.63
27 INT20579 Transcription of Akr1d1 9 0.04 2.91 8.37
28 INT7588 Regulation of NPY 13 0.44 6.97 7.97
29 INT6856 Gene_expression of Cckbr 10 0.77 1.8 7.69
30 INT51062 Negative_regulation of Cckbr 7 0.59 1.98 7.68
31 INT22782 Localization of PRSS1 25 0.81 14.44 7.34
32 INT18463 Localization of Pgc 31 0.78 3.74 7.3
33 INT16268 Binding of HTR3A 15 0.47 7.38 7.18
34 INT128369 Localization of PYY 27 0.79 10.39 7.06
35 INT31226 Localization of PPY 20 0.78 9.93 6.8
36 INT83745 Gene_expression of SULT2A1 34 0.59 15.96 6.66
37 INT24946 Binding of PRSS1 23 0.47 16.75 6.41
38 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18
39 INT24724 Positive_regulation of Gene_expression of SST 11 0.67 7.51 6.12
40 INT16568 Positive_regulation of HTR3A 14 0.67 4.82 6.01
41 INT50572 Localization of Akr1d1 14 0.59 0.51 5.87
42 INT23725 Gene_expression of CCKAR 14 0.55 0.14 5.3
43 INT22022 Regulation of PPY 8 0.26 5.52 5.02
44 INT26008 Positive_regulation of Cckbr 5 0.65 1.47 5.01
45 INT67195 Negative_regulation of Gene_expression of SST 7 0.42 6.98 4.88
46 INT23126 Regulation of HTR3A 10 0.60 5.42 4.81
47 INT26754 Positive_regulation of Positive_regulation of Akr1d1 8 0.05 0.28 4.75
48 INT14714 Negative_regulation of NPY 10 0.58 4.41 4.52
49 INT54776 Binding of Cckbr 5 0.42 0 4.45
50 INT16569 Negative_regulation of HTR3A 14 0.57 6.91 4.42
51 INT3327 Protein_catabolism of PRSS1 22 1.00 6.96 4.29
52 INT20052 Negative_regulation of UGT1A1 12 0.58 4.51 4.29
53 INT18461 Positive_regulation of Localization of Pgc 17 0.65 4.41 3.99
54 INT38249 Positive_regulation of VIPR1 9 0.40 2.58 3.96
55 INT140542 Gene_expression of SSTR2 18 0.65 13.58 3.94
56 INT14930 Regulation of Gene_expression of SST 12 0.45 6.86 3.89
57 INT24366 Positive_regulation of Localization of NPY 4 0.50 4.01 3.79
58 INT52170 Regulation of Cckbr 5 0.58 1.34 3.69
59 INT35864 Regulation of PRSS1 19 0.61 8.14 3.63
60 INT170182 Negative_regulation of SULT2A1 14 0.34 11.47 3.63
61 INT23728 Negative_regulation of CCKAR 6 0.42 0.48 3.53
62 INT38032 Protein_catabolism of SST 5 0.98 2.23 3.34
63 INT122511 Negative_regulation of Binding of Akr1d1 1 0.04 0.14 3.29
64 INT18462 Positive_regulation of Pgc 29 0.57 22.55 3.24
65 INT24296 Binding of NPY 6 0.48 2.03 3.23
66 INT12241 Negative_regulation of Positive_regulation of PRSS1 6 0.43 5.39 3.22
67 INT36225 Gene_expression of PYY 9 0.76 4.43 3.15
68 INT625 Localization of PGC 35 0.80 11.33 3.05
69 INT115857 Gene_expression of PRSS3 10 0.72 4.13 2.96
70 INT239083 Binding of PPY 9 0.32 7.59 2.9
71 INT2196 Positive_regulation of TFF2 4 0.50 0.19 2.85
72 INT58751 Positive_regulation of Binding of SST 4 0.70 2.51 2.67
73 INT13904 Transcription of NPY 6 0.67 1.57 2.66
74 INT23534 Regulation of CCKAR 8 0.32 0.17 2.56
75 INT13733 Localization of SSTR1 8 0.65 3.11 2.49
76 INT152163 Positive_regulation of GALR2 4 0.70 3.69 2.43
77 INT40505 Positive_regulation of CCKAR 3 0.40 0 2.42
78 INT50571 Regulation of Gene_expression of Akr1d1 3 0.33 0.33 2.4
79 INT3182 Negative_regulation of PPY 12 0.42 4.65 2.28
80 INT95792 Regulation of SSTR1 5 0.57 2.98 2.27
81 INT47543 Positive_regulation of Chrm3 11 0.38 5.23 2.17
82 INT49769 Binding of SSTR2 4 0.48 1.39 2.14
83 INT104980 Transcription of PRSS1 5 0.69 3.54 2.12
84 INT20578 Positive_regulation of Gene_expression of Akr1d1 5 0.22 0.26 2.1
85 INT20098 Positive_regulation of PGC 11 0.64 4.78 2.07
86 INT99410 Positive_regulation of UGT1A1 10 0.45 2.2 2.07
87 INT116097 Positive_regulation of Gene_expression of TFF2 2 0.69 0.15 2.05
88 INT101631 Phosphorylation of SST 1 0.66 0 2.04
89 INT170185 Localization of SULT2A1 4 0.47 4.65 2
90 INT64682 Positive_regulation of Gene_expression of NPY 4 0.49 3.19 1.96
91 INT51038 Regulation of Localization of Pgc 5 0.58 0 1.94
92 INT203021 Positive_regulation of Localization of PYY 8 0.47 4.86 1.87
93 INT148944 Transcription of UGT1A1 3 0.59 0.07 1.84
94 INT37754 Negative_regulation of Pgc 4 0.48 1.54 1.82
95 INT94181 Gene_expression of VIPR1 7 0.58 0.55 1.79
96 INT30373 Localization of CCKAR 5 0.68 0.17 1.79
97 INT94163 Negative_regulation of UCN2 11 0.57 6.86 1.75
98 INT45692 Positive_regulation of Gene_expression of PRSS1 8 0.49 4.07 1.73
99 INT115858 Positive_regulation of PRSS3 5 0.50 2.06 1.72
100 INT35937 Negative_regulation of Positive_regulation of Akr1d1 2 0.40 0 1.72
101 INT30573 Regulation of Regulation of SST 2 0.18 1.55 1.69
102 INT73616 Positive_regulation of Localization of Akr1d1 2 0.07 0 1.68
103 INT193415 Positive_regulation of GALR1 1 0.36 2.27 1.66
104 INT86092 Localization of HTR3A 4 0.78 0.52 1.64
105 INT170181 Regulation of SULT2A1 4 0.26 5.15 1.56
106 INT39519 Positive_regulation of Localization of PRSS1 6 0.69 3.78 1.52
107 INT101632 Positive_regulation of Phosphorylation of SST 1 0.40 0 1.52
108 INT327565 Binding of AKR1B10 1 0.03 1.47 1.48
109 INT78889 Binding of UGT1A1 10 0.47 3.41 1.47
110 INT61553 Positive_regulation of Regulation of Akr1d1 1 0.05 0 1.46
111 INT38111 Negative_regulation of VIPR1 3 0.12 3.79 1.45
112 INT35654 Gene_expression of Pgc 6 0.65 7.97 1.44
113 INT136720 Gene_expression of PRSS2 6 0.50 4.99 1.43
114 INT60137 Negative_regulation of Protein_catabolism of SST 2 0.17 0.93 1.43
115 INT13734 Regulation of Localization of SSTR1 1 0.23 0 1.43
116 INT19892 Negative_regulation of Negative_regulation of SST 1 0.41 0.57 1.43
117 INT124407 Gene_expression of SSTR1 4 0.55 5.55 1.41
118 INT131297 Positive_regulation of Gene_expression of HTR3A 3 0.49 0.34 1.4
119 INT115861 Transcription of PRSS3 2 0.67 1.45 1.4
120 INT198453 Negative_regulation of MUC5AC 12 0.58 12.96 1.38
121 INT168954 Binding of CCKAR 1 0.28 0 1.36
122 INT150728 Positive_regulation of Gene_expression of PRSS3 1 0.09 1.19 1.36
123 INT23727 Positive_regulation of Gene_expression of CCKAR 4 0.31 0 1.34
124 INT141010 Positive_regulation of Gene_expression of Cckbr 1 0.44 0.67 1.34
125 INT629 Negative_regulation of Localization of PGC 8 0.45 5.79 1.33
126 INT152167 Regulation of GALR2 2 0.44 2.23 1.33
127 INT36643 Negative_regulation of Ctrb1 2 0.16 0.08 1.33
128 INT141009 Transcription of Cckbr 1 0.47 0.67 1.33
129 INT3333 Positive_regulation of Protein_catabolism of PRSS1 3 0.49 2.23 1.29
130 INT60683 Regulation of VIPR1 3 0.07 1.53 1.27
131 INT24609 Regulation of Localization of NPY 2 0.26 0.36 1.26
132 INT32704 Negative_regulation of PGC 11 0.54 5.75 1.23
133 INT97474 Positive_regulation of UCN2 6 0.67 1.85 1.23
134 INT37250 Regulation of Localization of PPY 3 0.26 0.91 1.23
135 INT122171 Negative_regulation of AKR1C1 5 0.59 1.92 1.22
136 INT74849 Positive_regulation of Chrm3 5 0.64 1.71 1.2
137 INT51880 Regulation of Gene_expression of NPY 2 0.26 2.01 1.19
138 INT94162 Binding of UCN2 3 0.36 1.8 1.18
139 INT173004 Transcription of MUC5AC 2 0.56 1.33 1.18
140 INT41143 Localization of VIPR1 4 0.78 1.57 1.16
141 INT3181 Negative_regulation of Positive_regulation of PPY 3 0.42 1.19 1.16
142 INT78686 Protein_catabolism of PRSS3 2 0.88 1.5 1.15
143 INT100051 Binding of MUC5AC 20 0.32 14.21 1.14
144 INT115515 Positive_regulation of PRSS2 5 0.69 5.76 1.13
145 INT20576 Negative_regulation of Gene_expression of Akr1d1 2 0.03 0.23 1.13
146 INT219108 Negative_regulation of Gene_expression of MUC5AC 11 0.31 9.74 1.08
147 INT224407 Binding of PYY 1 0.35 0.91 1.07
148 INT85610 Positive_regulation of Positive_regulation of Cckbr 1 0.14 0.25 1.06
149 INT17544 Negative_regulation of Gene_expression of NPY 3 0.42 1.97 1.05
150 INT18408 Positive_regulation of Regulation of SST 2 0.45 0.51 1.05
151 INT144767 Gene_expression of UCN2 5 0.65 1.78 1.04
152 INT9182 Negative_regulation of Positive_regulation of SST 3 0.41 0.15 1.03
153 INT25172 Positive_regulation of Localization of PGC 9 0.68 3.01 1.02
154 INT41142 Binding of VIPR1 5 0.20 0.07 1.02
155 INT203025 Regulation of Gene_expression of PYY 2 0.44 1.31 1.01
156 INT24761 Positive_regulation of Negative_regulation of SST 2 0.49 0.86 1.01
157 INT112991 Positive_regulation of Gene_expression of PPY 7 0.29 6.26 0.99
158 INT144461 Negative_regulation of SSTR2 2 0.49 1.03 0.98
159 INT106960 Gene_expression of Chrm3 15 0.69 6.29 0.96
160 INT94180 Positive_regulation of Gene_expression of VIPR1 3 0.10 0.61 0.96
161 INT66605 Localization of TFF2 2 0.29 0 0.96
162 INT173014 Positive_regulation of Gene_expression of MUC5AC 10 0.45 4.82 0.94
163 INT84389 Transcription of HTR3A 2 0.69 0.3 0.94
164 INT340382 Regulation of Regulation of PPY 1 0.12 0.94 0.94
165 INT82533 Regulation of Positive_regulation of Akr1d1 1 0.08 0 0.94
166 INT173021 Localization of MUC5AC 14 0.70 10.73 0.91
167 INT148401 Regulation of Chrm3 3 0.19 1.19 0.91
168 INT84094 Negative_regulation of Regulation of SST 1 0.05 0 0.89
169 INT73950 Negative_regulation of Chrm3 1 0.41 0 0.88
170 INT58758 Positive_regulation of Binding of NPY 1 0.30 0.57 0.85
171 INT203023 Regulation of PYY 4 0.44 1.09 0.84
172 INT290532 Gene_expression of Ucn3 1 0.22 0.59 0.83
173 INT151943 Negative_regulation of Positive_regulation of UCN2 2 0.42 0.55 0.82
174 INT23726 Positive_regulation of Negative_regulation of CCKAR 1 0.08 0 0.82
175 INT24367 Negative_regulation of Localization of NPY 1 0.43 0.4 0.81
176 INT193417 Localization of GALR2 1 0.74 0.83 0.8
177 INT73827 Binding of TFF2 2 0.35 1.09 0.76
178 INT22446 Regulation of TFF2 1 0.08 0.17 0.76
179 INT91815 Positive_regulation of Positive_regulation of PRSS1 6 0.49 3.79 0.75
180 INT54353 Regulation of Transcription of Akr1d1 1 0.03 0.08 0.74
181 INT129756 Regulation of MUC5AC 7 0.34 6.45 0.7
182 INT78351 Gene_expression of GALR1 2 0.77 1.03 0.7
183 INT118133 Negative_regulation of Gene_expression of PRSS1 2 0.50 3.58 0.69
184 INT31576 Transcription of SST 5 0.69 0.89 0.68
185 INT35926 Gene_expression of NMU 5 0.75 1.34 0.66
186 INT156085 Negative_regulation of AKR1C2 3 0.54 0.79 0.66
187 INT20577 Negative_regulation of Transcription of Akr1d1 1 0.02 0.23 0.66
188 INT243477 Binding of SSTR1 3 0.26 3.49 0.65
189 INT149689 Binding of Chrm3 3 0.24 1.54 0.65
190 INT203029 Negative_regulation of Localization of PYY 1 0.40 0.66 0.64
191 INT115276 Gene_expression of AKR1C1 11 0.77 4.65 0.63
192 INT278674 Positive_regulation of Gene_expression of SULT2A1 9 0.29 2.04 0.63
193 INT168965 Negative_regulation of Binding of CCKAR 1 0.22 0 0.63
194 INT168966 Positive_regulation of Localization of CCKAR 1 0.29 0 0.62
195 INT25006 Negative_regulation of Gene_expression of CCKAR 1 0.30 0 0.62
196 INT38834 Positive_regulation of Positive_regulation of PPY 2 0.42 4.18 0.61
197 INT32159 Positive_regulation of Positive_regulation of NPY 2 0.45 0.09 0.61
198 INT215183 Positive_regulation of MUC5AC 4 0.45 2.78 0.6
199 INT48697 Gene_expression of Ctrb1 3 0.22 0.34 0.6
200 INT108911 Negative_regulation of Gene_expression of HTR3A 2 0.41 1.81 0.6
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