GO:0007596

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Name blood coagulation
Categary Process
Go Slim No
Go Link GO:0007596
Unique Molecular Interactions 4731
Total Molecular Interactions 6570
Total Single Events 49114
Pain Genes Associated 306

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for blood coagulation. They are ordered first by their pain relevance and then by number of times they were reported for blood coagulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT269444 Binding of RAB5A and HHIP 1 0.04 0 5.79
3 INT107331 Binding of PPBP and Adarb1 1 0.01 0 3.67
4 INT108472 Binding of NOS1 and PNOC 1 0.32 0.64 3.27
5 INT81708 POMC Regulation of Gene_expression of ITGAM 1 0.53 0.72 3.1
6 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
7 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76
8 INT69057 H2-M3 Regulation of Klkb1 1 0.00 0.42 2.71
9 INT103669 Hps4 Positive_regulation of Mors1 1 0.01 0 2.7
10 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
11 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
12 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
13 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
14 INT139723 PROC Positive_regulation of MAPK8 1 0.01 2.98 2.33
15 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
16 INT146930 CAP1 Regulation of ABCB1 1 0.29 0.3 2.19
17 INT66157 Binding of ALB and BDP1 1 0.11 0 2.13
18 INT107268 Binding of ITGAL and NCR3 1 0.01 2.76 2.07
19 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93
20 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
21 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
22 INT43447 Binding of H3 and Hps4 1 0.07 0 1.82
23 INT168010 Asap1 Positive_regulation of HBG2 1 0.01 3.03 1.82
24 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
25 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
26 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
27 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
28 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
29 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
30 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
31 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
32 INT103592 CAP1 Negative_regulation of Gene_expression of CPOX 1 0.19 1.52 1.64
33 INT24689 Binding of PLAT and Serpine1 1 0.00 3.77 1.64
34 INT187175 Binding of BSG and PPIA 1 0.14 2.23 1.64
35 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
36 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
37 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
38 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
39 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
40 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
41 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 1 0.27 0.56 1.58
42 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
43 INT81709 POMC Regulation of Gene_expression of ITGB2 1 0.40 0.34 1.57
44 INT81719 POMC Regulation of Gene_expression of ITGAL 1 0.35 0.34 1.57
45 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
46 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
47 INT81715 POMC Regulation of ITGB2 1 0.40 0.34 1.55
48 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
49 INT81721 POMC Regulation of ITGAM 1 0.39 0.34 1.55
50 INT81714 POMC Regulation of ITGAL 1 0.15 0.34 1.54
51 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
52 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5
53 INT166676 Binding of PRKCA and UGT1A6 1 0.30 0 1.5
54 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
55 INT31391 Binding of PRCP and Abpa 1 0.03 0.16 1.42
56 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
57 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
58 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
59 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
60 INT158762 Binding of Vwf and Mthfr 1 0.05 1.85 1.37
61 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
62 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
63 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
64 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
65 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34
66 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
67 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
68 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
69 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32
70 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
71 INT94367 Binding of ARRB1 and TP53INP2 1 0.25 0 1.3
72 INT139722 PROC Positive_regulation of CDCP1 1 0.00 1.61 1.29
73 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
74 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
75 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
76 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
77 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
78 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27
79 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
80 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26
81 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25
82 INT305408 Binding of KCNMA1 and ST8SIA2 1 0.01 0.09 1.24
83 INT202039 CAMK2N2 Negative_regulation of MMP1 1 0.00 0.73 1.24
84 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
85 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
86 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
87 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
88 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
89 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
90 INT181490 Tryptase Positive_regulation of F2rl1 1 0.13 1.83 1.21
91 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
92 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
93 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
94 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
95 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18
96 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
97 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18
98 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18
99 INT182159 Binding of HGF and DCPS 1 0.01 2.5 1.17
100 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17
101 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
102 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
103 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
104 INT212815 WAS Positive_regulation of CNR1 1 0.01 0.62 1.16
105 INT212824 WAS Positive_regulation of Cnr1 1 0.21 0.62 1.16
106 INT19535 Binding of ADRA1D and ALB 3 0.42 0.8 1.15
107 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
108 INT193288 CAP1 Positive_regulation of Pth 1 0.04 0.08 1.14
109 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
110 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
111 INT136989 EGF Negative_regulation of Positive_regulation of KCNJ2 1 0.04 1.09 1.1
112 INT107265 Binding of HLA-DRB1 and ITGAL 1 0.01 1.41 1.1
113 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
114 INT101715 PLAT Positive_regulation of NFKB1 2 0.11 0.99 1.09
115 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
116 INT164378 MAPK3 Positive_regulation of Transcription of PDYN 1 0.50 0.2 1.09
117 INT70270 Binding of ADRA2B and Pnoc 2 0.02 0.15 1.08
118 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
119 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08
120 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08
121 INT156238 Binding of F2rl1 and Tnfsf14 1 0.08 2.85 1.08
122 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
123 INT172757 Rnpep Positive_regulation of Hps4 1 0.00 0 1.08
124 INT187176 Binding of BSG and MMP1 1 0.09 1.18 1.08
125 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
126 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
127 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
128 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
129 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
130 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06
131 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
132 INT269443 Positive_regulation of Binding of RAB5A and HHIP 1 0.04 0 1.06
133 INT150787 ZNF398 Positive_regulation of Gene_expression of SPARC 1 0.13 1.02 1.05
134 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 1 0.40 0 1.05
135 INT97011 Binding of CALM3 and OPRM1 1 0.35 0 1.05
136 INT107566 Penk Regulation of Hps4 1 0.00 0.1 1.04
137 INT136988 EGF Negative_regulation of KCNJ2 1 0.04 1.09 1.04
138 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
139 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
140 INT107565 Hps4 Regulation of Mtr 1 0.00 0.1 1.04
141 INT118859 GNA14 Positive_regulation of STAT3 1 0.01 0.38 1.03
142 INT144069 Positive_regulation of TRPV1 Positive_regulation of Gene_expression of MMP1 1 0.43 1.35 1.03
143 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
144 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
145 INT106706 POMC Negative_regulation of Binding of FN1 1 0.19 0.79 1.02
146 INT54737 PPBP Regulation of NCOR2 1 0.01 0.15 1.01
147 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
148 INT38579 Binding of POMC and Hps4 1 0.00 0.32 0.99
149 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 0.30 0.38 0.99
150 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
151 INT124918 Binding of PLEK and Maob 1 0.10 1.05 0.98
152 INT73680 KNG1 Positive_regulation of ALB 1 0.51 0.38 0.98
153 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
154 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
155 INT69506 CA2 Positive_regulation of PRKCA 1 0.50 0.42 0.98
156 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
157 INT93306 Binding of TRPV1 and CAP1 2 0.18 0.07 0.97
158 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97
159 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97
160 INT195219 Binding of CPB2 and CSRP1 1 0.03 0.99 0.96
161 INT303690 KNG1 Positive_regulation of CPOX 1 0.01 0.76 0.96
162 INT93307 CAP1 Positive_regulation of TRPV1 1 0.15 0.07 0.96
163 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
164 INT66714 Negative_regulation of Binding of BDKRB1 and KNG1 1 0.13 0.22 0.96
165 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
166 INT48381 CSF2 Positive_regulation of ITGAM 2 0.30 0.38 0.95
167 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
168 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
169 INT302309 Hps4 Positive_regulation of Cia1 1 0.01 1.34 0.95
170 INT166790 HRAS Negative_regulation of Gene_expression of PTGER1 1 0.01 1.46 0.95
171 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
172 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
173 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
174 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
175 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
176 INT102554 HGF Positive_regulation of Phosphorylation of RPS6KA1 1 0.21 0.93 0.94
177 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
178 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
179 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
180 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
181 INT81329 Binding of ARRB1 and OPRK1 1 0.05 0.1 0.93
182 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
183 INT72213 Positive_regulation of PRKCA Regulation of Gene_expression of METTL3 1 0.05 0.17 0.93
184 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92
185 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
186 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92
187 INT138602 Negative_regulation of BCL2L2 Positive_regulation of F2 1 0.00 0.67 0.92
188 INT193291 Binding of CAP1 and Cfd 1 0.02 0.13 0.91
189 INT34271 Positive_regulation of WAS Positive_regulation of Oprd1 1 0.01 0 0.91
190 INT34273 WAS Regulation of Oprd1 1 0.00 0 0.91
191 INT138601 BCL2L2 Positive_regulation of F2 1 0.00 0.66 0.91
192 INT34272 WAS Positive_regulation of Oprd1 1 0.01 0 0.91
193 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
194 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
195 INT138862 ABCC2 Negative_regulation of ABCC4 1 0.63 0.24 0.9
196 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9
197 INT111924 Cpb2 Negative_regulation of Positive_regulation of Plg 1 0.02 1.29 0.9
198 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
199 INT85783 PRKG1 Regulation of Prkcg 1 0.09 0.38 0.9
200 INT220744 EGF Positive_regulation of Gene_expression of KRT20 1 0.01 1.26 0.9

Single Events

The table below shows the top 100 pain related interactions that have been reported for blood coagulation. They are ordered first by their pain relevance and then by number of times they were reported in blood coagulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85
3 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71
4 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32
5 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
6 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
7 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
8 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
9 INT7134 Localization of KNG1 127 0.79 65.73 67.97
10 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
11 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
12 INT546 Binding of ALB 311 0.48 85.98 60.14
13 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29
14 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74
15 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72
16 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49
17 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
18 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
19 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75
20 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76
21 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54
22 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
23 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84
24 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23
25 INT16290 Gene_expression of BSG 60 0.68 38.73 32.86
26 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
27 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23
28 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
29 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78
30 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72
31 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
32 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47
33 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43
34 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97
35 INT3076 Regulation of KNG1 52 0.60 20.39 27.89
36 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
37 INT9296 Negative_regulation of PLEK 100 0.57 36.65 27.52
38 INT94658 Positive_regulation of F2rl1 51 0.70 33.65 27.46
39 INT3167 Binding of KNG1 48 0.48 23.26 26.77
40 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75
41 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7
42 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
43 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14
44 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
45 INT48766 Regulation of NOS1 73 0.61 37.01 24.59
46 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96
47 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
48 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
49 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62
50 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71
51 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
52 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
53 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72
54 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68
55 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52
56 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
57 INT11157 Binding of EGF 88 0.48 53.73 21.25
58 INT4535 Localization of PROC 106 0.73 76.24 21.1
59 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
60 INT90849 Gene_expression of F2rl1 55 0.78 31.31 20.65
61 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41
62 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
63 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09
64 INT81210 Positive_regulation of PRKG1 71 0.70 26.83 19.89
65 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86
66 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86
67 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
68 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
69 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99
70 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
71 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
72 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35
73 INT118512 Gene_expression of F2r 33 0.63 26.56 18.26
74 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13
75 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88
76 INT2216 Gene_expression of SELL 92 0.77 59.29 17.71
77 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
78 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
79 INT1767 Positive_regulation of PROC 83 0.67 54.14 17
80 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
81 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
82 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
83 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34
84 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26
85 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
86 INT52591 Gene_expression of KCNMA1 78 0.76 13.95 15.55
87 INT61172 Gene_expression of PRKCA 34 0.77 8.89 15.47
88 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
89 INT30440 Gene_expression of Hps4 15 0.29 2.39 15.31
90 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15
91 INT103210 Localization of MMP1 43 0.78 12.15 15.13
92 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82
93 INT18430 Positive_regulation of Hps4 14 0.24 0.81 14.82
94 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8
95 INT25493 Gene_expression of TFPI 74 0.76 39.44 14.78
96 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55
97 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31
98 INT22276 Gene_expression of TBXA2R 65 0.77 23.22 14.21
99 INT17035 Positive_regulation of TFPI 55 0.61 34.88 14.18
100 INT104674 Positive_regulation of F2rl1 35 0.65 27.76 14.16
101 INT72127 Protein_catabolism of MMRN1 68 0.52 56 14.13
102 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
103 INT59870 Gene_expression of F3 51 0.65 51.83 14.01
104 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98
105 INT18773 Localization of ALB 117 0.80 69.18 13.8
106 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68
107 INT52714 Regulation of PRKCA 28 0.61 7.73 13.66
108 INT24684 Localization of PLAT 30 0.78 26.21 13.56
109 INT11071 Positive_regulation of PPBP 43 0.68 26.85 13.43
110 INT142621 Positive_regulation of Gene_expression of CD36 38 0.70 15.18 13.4
111 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79
112 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
113 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
114 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52
115 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
116 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47
117 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47
118 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4
119 INT29745 Binding of APP 47 0.48 26.49 12.4
120 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
121 INT11359 Gene_expression of PLAU 84 0.76 49.54 12.31
122 INT55687 Localization of TIMP1 47 0.74 30.24 12.31
123 INT61946 Positive_regulation of HGF 57 0.69 38.93 11.99
124 INT13287 Gene_expression of Cpb2 27 0.56 7.84 11.95
125 INT87698 Gene_expression of WAS 25 0.58 8.75 11.83
126 INT4047 Binding of F13A1 105 0.43 66.54 11.81
127 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64
128 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64
129 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47
130 INT72221 Localization of PRKCA 17 0.81 1.23 11.47
131 INT30236 Negative_regulation of Hps4 8 0.15 1.03 11.4
132 INT95369 Positive_regulation of Gene_expression of NOS2 36 0.55 25.09 11.37
133 INT18334 Positive_regulation of Cpb2 24 0.69 2.98 11.22
134 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
135 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03
136 INT13240 Gene_expression of TF 94 0.76 57.81 10.99
137 INT48912 Localization of NOS1 52 0.77 24.14 10.92
138 INT11479 Positive_regulation of KCNMA1 30 0.68 10.07 10.82
139 INT76434 Negative_regulation of PRKG1 25 0.58 10.36 10.81
140 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
141 INT18412 Binding of PLEK 49 0.47 17.82 10.72
142 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42
143 INT110178 Phosphorylation of MAPK14 40 0.68 19.38 10.37
144 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16
145 INT27937 Gene_expression of Klkb1 35 0.55 1.86 10.08
146 INT107606 Negative_regulation of MMP1 38 0.42 11.94 10.01
147 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93
148 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9
149 INT2036 Localization of EGF 42 0.77 21.5 9.74
150 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
151 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7
152 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69
153 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55
154 INT3366 Localization of PLEK 44 0.78 15.83 9.55
155 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43
156 INT41569 Regulation of APP 32 0.62 17.15 9.4
157 INT18830 Localization of TBXA2R 25 0.81 7.14 9.28
158 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
159 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13
160 INT93309 Positive_regulation of CAP1 17 0.43 11.4 9.13
161 INT48233 Negative_regulation of Gene_expression of MMP1 34 0.58 12.94 9.08
162 INT1168 Binding of PROC 62 0.38 44.15 9.04
163 INT18429 Localization of Hps4 8 0.31 1.23 9.01
164 INT4534 Regulation of PROC 38 0.33 19.81 8.99
165 INT860 Regulation of ALB 48 0.60 25.11 8.95
166 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82
167 INT8903 Gene_expression of IFNA2 58 0.71 38.23 8.68
168 INT34268 Binding of WAS 14 0.47 4.41 8.67
169 INT13432 Positive_regulation of Klkb1 23 0.57 5.36 8.65
170 INT28521 Gene_expression of HBG2 56 0.77 16.62 8.64
171 INT34777 Localization of IGF1 82 0.80 42.68 8.62
172 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56
173 INT89677 Gene_expression of PRKG1 38 0.78 13.98 8.56
174 INT93310 Gene_expression of CAP1 14 0.58 3.07 8.55
175 INT16460 Negative_regulation of PPBP 21 0.57 13.86 8.54
176 INT4046 Positive_regulation of HBG2 42 0.69 13.66 8.51
177 INT109005 Gene_expression of Proc 61 0.75 37.86 8.49
178 INT209866 Regulation of Gene_expression of CD36 27 0.60 10.04 8.42
179 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
180 INT48908 Transcription of NOS1 27 0.55 13.46 8.39
181 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37
182 INT15592 Positive_regulation of F2r 17 0.67 8.66 8.36
183 INT10969 Positive_regulation of PLEK 33 0.67 16.96 8.35
184 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29
185 INT44003 Gene_expression of F3 40 0.75 27.92 8.29
186 INT12975 Regulation of PLEK 21 0.60 13.62 8.28
187 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25
188 INT71785 Gene_expression of MAPK3 22 0.75 11.35 8.21
189 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15
190 INT117497 Positive_regulation of F2r 18 0.57 14.45 8.13
191 INT87699 Positive_regulation of WAS 16 0.45 5.84 8.03
192 INT26551 Positive_regulation of Gene_expression of KNG1 19 0.67 11.05 7.98
193 INT2271 Gene_expression of F2 51 0.76 30.21 7.97
194 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
195 INT1925 Gene_expression of PLAT 47 0.75 34.76 7.88
196 INT36678 Binding of TIMP1 33 0.36 14.99 7.87
197 INT11568 Gene_expression of ADORA2A 14 0.73 1.51 7.79
198 INT39406 Positive_regulation of OLR1 45 0.70 37.8 7.72
199 INT178198 Gene_expression of C3 62 0.78 39.5 7.69
200 INT91618 Positive_regulation of Phosphorylation of MAPK3 21 0.67 7.99 7.65
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