GO:0007597

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Name blood coagulation, intrinsic pathway
Categary Process
Go Slim No
Go Link GO:0007597
Unique Molecular Interactions 264
Total Molecular Interactions 347
Total Single Events 2510
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for blood coagulation, intrinsic pathway. They are ordered first by their pain relevance and then by number of times they were reported for blood coagulation, intrinsic pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
2 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
3 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
4 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
5 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
6 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
7 INT31391 Binding of PRCP and Abpa 1 0.03 0.16 1.42
8 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
9 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
10 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
11 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
12 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 0.30 0.38 0.99
13 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
14 INT73680 KNG1 Positive_regulation of ALB 1 0.51 0.38 0.98
15 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97
16 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97
17 INT303690 KNG1 Positive_regulation of CPOX 1 0.01 0.76 0.96
18 INT66714 Negative_regulation of Binding of BDKRB1 and KNG1 1 0.13 0.22 0.96
19 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92
20 INT138602 Negative_regulation of BCL2L2 Positive_regulation of F2 1 0.00 0.67 0.92
21 INT138601 BCL2L2 Positive_regulation of F2 1 0.00 0.66 0.91
22 INT84369 Ngf Positive_regulation of KNG1 1 0.04 0.29 0.89
23 INT96008 Binding of KNG1 and EBP 1 0.01 0.15 0.88
24 INT96010 KNG1 Positive_regulation of Binding of MTG1 1 0.32 0.15 0.88
25 INT96009 KNG1 Positive_regulation of MTG1 1 0.32 0.15 0.88
26 INT225690 KNG1 Positive_regulation of TRPV1 1 0.42 0.7 0.83
27 INT193322 KNG1 Positive_regulation of Prh1 1 0.00 0.51 0.83
28 INT150636 Binding of KNG1 and CD177 1 0.10 0.37 0.79
29 INT129415 KNG1 Positive_regulation of Trpv1 1 0.05 0.39 0.76
30 INT107028 KNG1 Regulation of Des 1 0.01 1.7 0.76
31 INT332699 Binding of KNG1 and TRGC1 1 0.16 3.37 0.75
32 INT106999 F2 Positive_regulation of PAR4 3 0.06 1.83 0.72
33 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
34 INT31389 Negative_regulation of Binding of PRCP and Abpa 1 0.02 0.09 0.72
35 INT31390 Positive_regulation of Binding of PRCP and Abpa 1 0.04 0.08 0.71
36 INT121458 KNG1 Positive_regulation of Localization of Trpv1 1 0.16 0.43 0.69
37 INT126779 Binding of Serpinc1 and F8 1 0.00 1.52 0.69
38 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
39 INT126781 Binding of F10 and Serpinc1 1 0.00 1.51 0.69
40 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
41 INT150338 Binding of F2 and F2R 1 0.11 0.4 0.67
42 INT95546 KNG1 Positive_regulation of Ptgir 1 0.02 0.93 0.64
43 INT96472 KNG1 Positive_regulation of Gene_expression of TRPV1 1 0.01 0.22 0.64
44 INT34005 YY1 Regulation of KNG1 1 0.04 0.38 0.63
45 INT121460 KNG1 Positive_regulation of Bdkrb2 1 0.08 0.44 0.62
46 INT121459 Bdkrb2 Positive_regulation of KNG1 1 0.09 0.44 0.62
47 INT337323 KNG1 Positive_regulation of PRKCA 1 0.15 0.17 0.62
48 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62
49 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61
50 INT34840 Binding of KNG1 and PDYN 1 0.01 0 0.61
51 INT31392 Binding of PRCP and Gpr37 1 0.01 0.1 0.6
52 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58
53 INT120347 Binding of KNG1 and MYC 1 0.21 0.17 0.58
54 INT126641 Binding of KNG1 and Bdkrb2 1 0.11 0.42 0.55
55 INT303721 KNG1 Positive_regulation of Bdkrb1 1 0.05 0.75 0.52
56 INT172248 Binding of KNG1 and NCOR2 1 0.02 0.19 0.52
57 INT303722 KNG1 Positive_regulation of Bdkrb2 1 0.01 0.7 0.52
58 INT33415 KNG1 Positive_regulation of GBP1 1 0.02 0.43 0.51
59 INT106074 IL1B Positive_regulation of Gene_expression of A2M 1 0.03 0.75 0.49
60 INT106072 NFKB1 Positive_regulation of Gene_expression of A2M 1 0.19 0.75 0.49
61 INT84515 IRF6 Positive_regulation of Gene_expression of F2 1 0.02 0.15 0.49
62 INT84520 Gene_expression of F2 Positive_regulation of F13A1 1 0.03 0.16 0.49
63 INT58663 Binding of KNG1 and Ugt1a2 1 0.02 0.4 0.47
64 INT341622 Binding of F2 and CTRC 1 0.06 1.22 0.46
65 INT173295 F2 Positive_regulation of OR1S1 1 0.01 0.15 0.46
66 INT70183 Binding of PRCP and NCOR2 1 0.04 0.08 0.46
67 INT327090 Negative_regulation of F12 Negative_regulation of Gene_expression of KNG1 1 0.00 0.51 0.45
68 INT96245 Negative_regulation of Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
69 INT96246 Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
70 INT201092 Binding of KNG1 and NGF 1 0.00 0.31 0.43
71 INT201120 Binding of KNG1 and Par2 1 0.00 0.3 0.42
72 INT290269 KNG1 Positive_regulation of Binding of MID1 1 0.02 1.06 0.41
73 INT162043 F2 Positive_regulation of Gene_expression of OSM 1 0.44 1.13 0.41
74 INT290270 KNG1 Positive_regulation of MID1 1 0.02 1.06 0.41
75 INT162041 F2 Positive_regulation of Positive_regulation of FOS 1 0.13 1.14 0.41
76 INT85511 Binding of KNG1 and Bdkrb2 1 0.54 0.51 0.4
77 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37
78 INT229222 Negative_regulation of ACE Negative_regulation of Protein_catabolism of KNG1 1 0.06 0.53 0.37
79 INT70185 PRCP Positive_regulation of Gene_expression of FOS 1 0.05 0.1 0.37
80 INT26552 Gene_expression of Mras Positive_regulation of Gene_expression of KNG1 1 0.03 0.07 0.36
81 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35
82 INT136007 Binding of INSRR and KNG1 1 0.00 0.17 0.34
83 INT323352 Binding of F8 and VWF 5 0.08 2.22 0.33
84 INT230855 KNG1 Regulation of NOS1 2 0.03 0.94 0.33
85 INT285566 F8 Negative_regulation of IL2 1 0.00 0.62 0.33
86 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33
87 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32
88 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32
89 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32
90 INT35216 Binding of KNG1 and Thop1 1 0.01 0 0.32
91 INT337327 KNG1 Positive_regulation of BDKRB2 1 0.21 0.4 0.32
92 INT195665 APC Negative_regulation of F8 1 0.04 1.53 0.32
93 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
94 INT196618 Binding of KNG1 and Positive_regulation of NA 1 0.01 0.19 0.32
95 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32
96 INT196623 Binding of KNG1 and Positive_regulation of DNAH8 1 0.01 0.19 0.32
97 INT170994 KNG1 Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.32
98 INT123397 F2 Positive_regulation of Gene_expression of PTAFR 1 0.05 0.51 0.32
99 INT162042 F2 Regulation of OSM 1 0.17 1.17 0.31
100 INT195669 Binding of F2 and PROC 1 0.04 1.44 0.31
101 INT66243 KNG1 Positive_regulation of Ptgis 1 0.01 0 0.3
102 INT44984 KNG1 Regulation of Ltc4s 1 0.01 0.17 0.3
103 INT162045 F2 Positive_regulation of Phosphorylation of MAPK3 1 0.30 0.99 0.3
104 INT196641 Binding of KNG1 and Negative_regulation of DNAH8 1 0.01 0.19 0.29
105 INT196612 Binding of KNG1 and Negative_regulation of NA 1 0.01 0.19 0.29
106 INT57498 Vwf Positive_regulation of F8 1 0.00 0.36 0.29
107 INT70186 PRCP Positive_regulation of INSRR 1 0.01 0.09 0.29
108 INT162039 F2 Regulation of Gene_expression of OSM 1 0.29 0.94 0.29
109 INT162044 F2 Positive_regulation of Localization of FOS 1 0.32 0.9 0.28
110 INT94849 A2M Negative_regulation of Gene_expression of COL7A1 1 0.01 0.27 0.28
111 INT162040 F2 Positive_regulation of Localization of JUN 1 0.20 0.9 0.28
112 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27
113 INT196626 Binding of DNAH8 and KNG1 1 0.00 0.08 0.27
114 INT196613 Binding of KNG1 and NA 1 0.01 0.08 0.27
115 INT265830 KNG1 Positive_regulation of Localization of BGN 1 0.02 0.33 0.27
116 INT220681 Binding of F10 and tf 1 0.03 1.47 0.26
117 INT308120 Binding of F2 and F10 2 0.07 1.25 0.25
118 INT267624 Klk1 Positive_regulation of KNG1 1 0.05 0.52 0.25
119 INT267596 KNG1 Positive_regulation of Gene_expression of PLA2G6 1 0.01 0.87 0.25
120 INT64726 Ace Negative_regulation of KNG1 1 0.01 0.26 0.25
121 INT64727 Ace Positive_regulation of KNG1 1 0.01 0.26 0.25
122 INT191500 ACE Positive_regulation of Localization of KNG1 1 0.10 0.17 0.24
123 INT239238 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.01 0.46 0.24
124 INT341538 F2 Positive_regulation of F2RL1 1 0.02 0.68 0.24
125 INT63420 F2 Positive_regulation of Gene_expression of ITGA2B 1 0.14 0.45 0.23
126 INT63421 F2 Positive_regulation of Gene_expression of SELP 1 0.09 0.45 0.23
127 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
128 INT173292 F2 Positive_regulation of EGF 1 0.00 0.07 0.23
129 INT70182 PRCP Positive_regulation of IER3 1 0.15 0.1 0.22
130 INT265828 ACE Regulation of Gene_expression of KNG1 1 0.32 0.83 0.22
131 INT281901 Binding of KNG1 and NOS3 1 0.05 0.17 0.22
132 INT332700 Binding of F12 and KNG1 1 0.15 1.05 0.21
133 INT82094 Binding of KNG1 and CLPP 1 0.03 0.42 0.21
134 INT281903 BDKRB1 Positive_regulation of KNG1 1 0.03 0.32 0.21
135 INT220682 tf Positive_regulation of Positive_regulation of F10 1 0.04 0.67 0.19
136 INT104702 KNG1 Negative_regulation of Anpep 1 0.11 0.47 0.19
137 INT326464 KNG1 Positive_regulation of SERPING1 1 0.19 1.53 0.18
138 INT250550 Binding of F12 and CHDH 1 0.05 2.26 0.17
139 INT329324 KNG1 Positive_regulation of Localization of ecs 1 0.00 1.16 0.17
140 INT83514 SERPINC1 Negative_regulation of F2 2 0.16 0.62 0.16
141 INT301907 Binding of THBD and VWF 1 0.02 1.71 0.16
142 INT83512 F2 Negative_regulation of PLAU 1 0.27 0.57 0.16
143 INT109887 F2 Negative_regulation of F8 1 0.00 1.32 0.16
144 INT83513 Negative_regulation of SERPINC1 Negative_regulation of F2 1 0.16 0.64 0.16
145 INT83515 F2 Positive_regulation of PLAU 1 0.31 0.57 0.16
146 INT83511 F2 Negative_regulation of PRH1 1 0.01 0.6 0.15
147 INT37659 IGHG3 Negative_regulation of F2 1 0.06 0.79 0.15
148 INT240768 Binding of F2 and F13A1 1 0.07 2.25 0.15
149 INT77159 Positive_regulation of KLK1 Positive_regulation of KNG1 1 0.04 0.28 0.15
150 INT109886 F2 Negative_regulation of Serpinc1 1 0.00 1.18 0.15
151 INT232018 Binding of SERPING1 and KNG1 1 0.15 0.81 0.14
152 INT191001 F3 Positive_regulation of F2 1 0.00 0.62 0.14
153 INT94850 A2M Negative_regulation of Gene_expression of PIP 1 0.01 0.14 0.14
154 INT107635 KNG1 Regulation of Slc25a1 1 0.00 0.1 0.13
155 INT323351 Positive_regulation of Binding of F8 and VWF 1 0.03 0.8 0.13
156 INT107622 KNG1 Regulation of AP4B1 1 0.19 0.1 0.13
157 INT107005 F2 Positive_regulation of PRSS1 1 0.00 0.28 0.13
158 INT221254 Binding of KNG1 and Akt1 1 0.00 0.13 0.13
159 INT232015 SERPING1 Negative_regulation of F12 2 0.24 1.19 0.12
160 INT329317 ACE Regulation of Positive_regulation of KNG1 1 0.02 1.05 0.12
161 INT14775 F8 Negative_regulation of Ins1 1 0.48 0 0.12
162 INT195710 SERPINC1 Positive_regulation of F2 1 0.08 0.69 0.11
163 INT195711 Negative_regulation of SERPINC1 Positive_regulation of F2 1 0.08 0.7 0.11
164 INT229364 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.02 0.86 0.11
165 INT347515 Binding of GP1BA and Vwf 1 0.01 0.19 0.11
166 INT232017 F12 Positive_regulation of PLG 1 0.03 0.52 0.11
167 INT8677 Binding of F8 and ANGPTL5 1 0.03 0.48 0.1
168 INT8676 Positive_regulation of Binding of F8 and ANGPTL5 1 0.04 0.48 0.1
169 INT8673 Binding of F2 and F8 1 0.08 0.48 0.1
170 INT8672 Positive_regulation of Binding of F2 and F8 1 0.11 0.48 0.1
171 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1
172 INT8675 Positive_regulation of Binding of F2 and F3 2 0.17 0.43 0.09
173 INT8671 Binding of F2 and F3 2 0.13 0.42 0.09
174 INT232019 F12 Positive_regulation of TRGC1 1 0.00 0.57 0.09
175 INT196619 KNG1 Regulation of DNAH8 1 0.00 0.62 0.09
176 INT298502 F10 Positive_regulation of F2 1 0.00 0.12 0.09
177 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09
178 INT196645 KNG1 Regulation of NA 1 0.00 0.62 0.09
179 INT81998 Binding of F13A1 and F8 1 0.00 0.47 0.09
180 INT343794 Binding of F8 and PTPRC 1 0.00 0.69 0.09
181 INT61217 Negative_regulation of PRTN3 Negative_regulation of F2 1 0.01 0.16 0.08
182 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08
183 INT232011 SERPING1 Regulation of Negative_regulation of SERPINE1 1 0.01 0.45 0.07
184 INT230853 Binding of SELE and VWF 1 0.06 1.3 0.07
185 INT37547 Binding of GP1BA and F8 1 0.03 0.15 0.07
186 INT191002 F2 Positive_regulation of Gene_expression of IL8 1 0.02 0.46 0.06
187 INT251645 Binding of SERPING1 and CD79A 1 0.10 1.31 0.06
188 INT232009 Positive_regulation of F12 Negative_regulation of Localization of KNG1 1 0.01 0.19 0.05
189 INT214847 Binding of VWF and ANGPTL5 1 0.03 1.16 0.05
190 INT265735 VEGFA Positive_regulation of Binding of KLKB1 1 0.04 0.36 0.04
191 INT327162 Binding of SERPING1 and F12 1 0.05 0.29 0.04
192 INT284096 Binding of MAP4 and VWF 1 0.35 0.82 0.04
193 INT232013 SERPING1 Negative_regulation of C1S 1 0.24 0.72 0.04
194 INT232012 SERPING1 Negative_regulation of C1R 1 0.18 0.72 0.04
195 INT265745 FLT1 Positive_regulation of Binding of KLKB1 1 0.04 0.36 0.04
196 INT269575 F2 Positive_regulation of CSH1 1 0.00 0.09 0.04
197 INT269579 F2 Positive_regulation of PAFAH2 1 0.00 0.09 0.04
198 INT261733 F2 Regulation of COL5A2 1 0.03 0.21 0.03
199 INT331881 F2 Positive_regulation of F8 1 0.10 0.53 0.03
200 INT206429 Binding of PRCP and SULT1B1 1 0.16 0.14 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for blood coagulation, intrinsic pathway. They are ordered first by their pain relevance and then by number of times they were reported in blood coagulation, intrinsic pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
2 INT7134 Localization of KNG1 127 0.79 65.73 67.97
3 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74
4 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23
5 INT3076 Regulation of KNG1 52 0.60 20.39 27.89
6 INT3167 Binding of KNG1 48 0.48 23.26 26.77
7 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
8 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47
9 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
10 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56
11 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15
12 INT26551 Positive_regulation of Gene_expression of KNG1 19 0.67 11.05 7.98
13 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51
14 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17
15 INT21647 Negative_regulation of Positive_regulation of KNG1 11 0.43 5.54 5.73
16 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56
17 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5
18 INT2919 Negative_regulation of F8 47 0.59 23.48 5.1
19 INT10889 Gene_expression of F8 60 0.78 41.36 5.06
20 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9
21 INT144481 Gene_expression of SERPING1 55 0.77 50.4 4.75
22 INT9842 Binding of F2 36 0.47 22.79 4.42
23 INT35609 Negative_regulation of F10 37 0.57 17.15 4.41
24 INT49217 Positive_regulation of Positive_regulation of KNG1 7 0.41 3.64 4.18
25 INT44323 Positive_regulation of F8 32 0.60 24.88 3.89
26 INT220078 Positive_regulation of Negative_regulation of KNG1 3 0.13 5.03 3.41
27 INT55409 Localization of VWF 17 0.80 8.99 3.06
28 INT46201 Gene_expression of KLKB1 21 0.53 3.01 2.87
29 INT10893 Binding of VWF 27 0.47 25.02 2.82
30 INT10141 Gene_expression of A2M 11 0.35 9.37 2.75
31 INT14447 Localization of F2 20 0.79 12.77 2.67
32 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53
33 INT156130 Binding of SERPING1 29 0.42 26.16 2.52
34 INT39560 Positive_regulation of F10 25 0.67 10.67 2.5
35 INT699 Positive_regulation of A2M 16 0.66 10.49 2.5
36 INT94010 Positive_regulation of Localization of VWF 9 0.70 4.23 2.5
37 INT150640 Regulation of Binding of KNG1 3 0.35 1.31 2.2
38 INT23352 Negative_regulation of A2M 10 0.33 8.35 2.16
39 INT70962 Positive_regulation of SERPING1 33 0.69 27.32 2.14
40 INT103327 Gene_expression of F8 45 0.71 32.5 2.12
41 INT6064 Positive_regulation of PRCP 4 0.40 0.26 1.92
42 INT88375 Negative_regulation of Localization of KNG1 4 0.39 1.12 1.91
43 INT62349 Negative_regulation of Protein_catabolism of KNG1 8 0.42 6.47 1.86
44 INT11481 Positive_regulation of F12 11 0.58 5.53 1.8
45 INT31388 Regulation of PRCP 3 0.45 0.55 1.76
46 INT88667 Negative_regulation of Gene_expression of F2 11 0.41 5.53 1.62
47 INT3249 Regulation of A2M 7 0.39 3.29 1.61
48 INT153156 Negative_regulation of KLKB1 5 0.48 7.88 1.6
49 INT23251 Positive_regulation of KLKB1 10 0.67 2.98 1.59
50 INT74818 Transcription of KNG1 6 0.67 2.71 1.59
51 INT107132 Regulation of Localization of KNG1 2 0.22 0.96 1.55
52 INT109881 Positive_regulation of Gene_expression of F8 11 0.47 12.97 1.54
53 INT77164 Binding of F12 8 0.47 2.66 1.48
54 INT12035 Regulation of F2 21 0.45 12.66 1.47
55 INT25353 Negative_regulation of F8 22 0.59 18.51 1.4
56 INT37076 Negative_regulation of Binding of KNG1 3 0.14 1.77 1.32
57 INT30091 Binding of PRCP 4 0.27 0.48 1.29
58 INT11496 Negative_regulation of F12 6 0.59 3.41 1.27
59 INT156672 Localization of SERPING1 10 0.74 12.15 1.25
60 INT96132 Gene_expression of F10 10 0.58 6.99 1.24
61 INT138343 Positive_regulation of Localization of F2 5 0.41 5.06 1.24
62 INT145953 Positive_regulation of Positive_regulation of F8 5 0.29 4.85 1.17
63 INT10890 Binding of F8 11 0.36 7.27 1.15
64 INT150638 Positive_regulation of Binding of KNG1 1 0.39 0.24 1.07
65 INT174273 Positive_regulation of Binding of F2 3 0.08 2.99 1.02
66 INT68844 Regulation of Positive_regulation of KNG1 2 0.44 2.22 1.02
67 INT191530 Regulation of Gene_expression of KNG1 4 0.26 0.71 0.96
68 INT103328 Binding of F8 9 0.44 11.89 0.93
69 INT114340 Positive_regulation of Protein_catabolism of KNG1 5 0.07 2.42 0.92
70 INT116459 Negative_regulation of VWF 8 0.58 5.66 0.89
71 INT144482 Negative_regulation of Gene_expression of SERPING1 8 0.43 6.06 0.89
72 INT44757 Gene_expression of PRCP 3 0.53 1.39 0.82
73 INT239234 Regulation of Protein_catabolism of KNG1 2 0.09 1.06 0.82
74 INT82845 Binding of F10 25 0.37 7.07 0.81
75 INT79181 Negative_regulation of GP1BA 2 0.06 2.23 0.8
76 INT2920 Regulation of F8 7 0.45 2.9 0.79
77 INT88957 Positive_regulation of Gene_expression of VWF 12 0.42 7.34 0.75
78 INT138606 Negative_regulation of Positive_regulation of F2 2 0.12 0.54 0.74
79 INT127487 Phosphorylation of KNG1 2 0.34 0.47 0.74
80 INT46202 Positive_regulation of Gene_expression of KLKB1 2 0.04 0 0.68
81 INT189322 Binding of A2M 7 0.29 12.1 0.66
82 INT83194 Binding of APOH 4 0.17 3.92 0.66
83 INT265802 Regulation of KLKB1 9 0.04 1.01 0.64
84 INT168000 Protein_catabolism of F2 6 0.63 2.19 0.63
85 INT88204 Positive_regulation of Gene_expression of PRCP 1 0.07 0.36 0.62
86 INT60115 Transcription of F8 2 0.08 3.05 0.58
87 INT55662 Negative_regulation of Negative_regulation of KNG1 4 0.36 3.45 0.57
88 INT3201 Positive_regulation of F9 11 0.49 5.12 0.56
89 INT109880 Negative_regulation of Gene_expression of F8 3 0.12 2.12 0.54
90 INT47117 Regulation of F8 2 0.07 1.09 0.52
91 INT64855 Localization of F8 5 0.68 3.29 0.51
92 INT99615 Gene_expression of GP1BA 12 0.75 2.98 0.5
93 INT221932 Gene_expression of F12 4 0.66 2.61 0.5
94 INT320172 Negative_regulation of Binding of F2 2 0.41 1.92 0.5
95 INT70188 Negative_regulation of Positive_regulation of PRCP 1 0.37 0.07 0.47
96 INT113641 Negative_regulation of Gene_expression of GP1BA 4 0.57 2.2 0.44
97 INT36793 Binding of KLKB1 3 0.40 0.51 0.42
98 INT133379 Negative_regulation of APOH 1 0.07 0.09 0.42
99 INT60035 Regulation of VWF 6 0.42 6.26 0.4
100 INT110261 Regulation of Gene_expression of F8 2 0.61 2.33 0.4
101 INT186480 Positive_regulation of Transcription of F8 1 0.06 2.08 0.4
102 INT162049 Phosphorylation of F2 3 0.47 0.99 0.39
103 INT47118 Gene_expression of F8 2 0.03 0.81 0.39
104 INT47116 Regulation of Gene_expression of F8 1 0.02 0.15 0.39
105 INT94026 Regulation of SERPING1 12 0.61 10.28 0.37
106 INT161436 Transcription of F2 2 0.69 1.21 0.36
107 INT81221 Positive_regulation of APOH 1 0.02 1.24 0.36
108 INT48772 Localization of A2M 3 0.78 2.83 0.35
109 INT316315 Negative_regulation of Binding of SERPING1 2 0.37 1.4 0.34
110 INT321886 Positive_regulation of F8 1 0.05 1.13 0.33
111 INT130344 Gene_expression of APOH 3 0.34 2.87 0.32
112 INT232021 Positive_regulation of Gene_expression of SERPING1 8 0.49 4.99 0.31
113 INT101176 Positive_regulation of Positive_regulation of VWF 3 0.49 1.73 0.31
114 INT88203 Negative_regulation of Gene_expression of PRCP 1 0.07 0.18 0.31
115 INT83195 Regulation of Binding of APOH 1 0.13 0.88 0.31
116 INT162051 Positive_regulation of Phosphorylation of F2 1 0.29 0.99 0.3
117 INT74817 Positive_regulation of Transcription of KNG1 1 0.49 0.18 0.3
118 INT229218 Negative_regulation of Gene_expression of F8 3 0.38 1.62 0.29
119 INT255014 Negative_regulation of Binding of F10 7 0.34 1.81 0.28
120 INT81223 Negative_regulation of Binding of VWF 3 0.42 2.09 0.28
121 INT77162 Regulation of Binding of F12 2 0.33 0.52 0.28
122 INT94009 Negative_regulation of Localization of VWF 1 0.43 0 0.28
123 INT36795 Localization of KLKB1 3 0.78 1.05 0.27
124 INT162802 Regulation of Gene_expression of F2 3 0.37 1.56 0.26
125 INT90653 Negative_regulation of Negative_regulation of F10 1 0.04 0.67 0.25
126 INT46524 Negative_regulation of Gene_expression of A2M 2 0.02 1.45 0.23
127 INT77165 Regulation of Positive_regulation of F12 1 0.38 0.28 0.23
128 INT77160 Positive_regulation of Binding of F12 1 0.42 0.28 0.23
129 INT198659 Protein_catabolism of F10 1 0.01 0.51 0.22
130 INT228644 Positive_regulation of Negative_regulation of SERPING1 5 0.46 4.21 0.21
131 INT17010 Regulation of GP1BA 2 0.03 0.93 0.18
132 INT35069 Transcription of F8 1 0.02 0.35 0.18
133 INT94854 Regulation of Negative_regulation of F2 1 0.11 0.18 0.18
134 INT20675 Binding of F8 2 0.19 1.15 0.17
135 INT3248 Positive_regulation of Positive_regulation of A2M 1 0.46 0.25 0.17
136 INT23708 Regulation of Regulation of A2M 1 0.02 0.68 0.17
137 INT58589 Regulation of F12 3 0.39 1.9 0.16
138 INT232025 Regulation of Gene_expression of SERPING1 3 0.56 1.75 0.15
139 INT40076 Negative_regulation of Positive_regulation of F8 1 0.02 0.07 0.15
140 INT284156 Positive_regulation of Negative_regulation of F2 1 0.01 1.71 0.15
141 INT136185 Positive_regulation of Binding of F8 2 0.64 1.4 0.14
142 INT313645 Regulation of Positive_regulation of F10 1 0.19 0.49 0.14
143 INT313646 Regulation of F10 1 0.19 0.49 0.14
144 INT316318 Phosphorylation of SERPING1 2 0.81 1.7 0.13
145 INT316316 Negative_regulation of Binding of F12 1 0.18 1.1 0.12
146 INT232026 Positive_regulation of Gene_expression of F12 1 0.03 0.58 0.11
147 INT203617 Localization of F8 9 0.74 4.36 0.1
148 INT123574 Localization of F12 1 0.15 0.25 0.09
149 INT307773 Regulation of Negative_regulation of KNG1 1 0.01 3.59 0.09
150 INT119002 Regulation of APOH 1 0.01 0.43 0.09
151 INT174262 Negative_regulation of Positive_regulation of F10 2 0.41 0.83 0.08
152 INT232027 Positive_regulation of Positive_regulation of SERPING1 2 0.46 1.48 0.08
153 INT64857 Positive_regulation of Localization of F8 1 0.42 0.08 0.08
154 INT3335 Negative_regulation of PRCP 3 0.27 0.35 0.07
155 INT93884 Positive_regulation of Negative_regulation of F8 1 0.36 0.25 0.07
156 INT96131 Positive_regulation of Gene_expression of F10 1 0.14 0.72 0.07
157 INT23040 Regulation of Positive_regulation of F8 1 0.38 0.75 0.07
158 INT314253 Transcription of VWF 1 0.33 0.07 0.04
159 INT265776 Regulation of Binding of KLKB1 1 0.04 0.36 0.04
160 INT221857 Regulation of Positive_regulation of F8 1 0.44 0.84 0.04
161 INT300190 Positive_regulation of Gene_expression of F8 2 0.50 0.81 0.03
162 INT229217 Regulation of Gene_expression of F8 2 0.41 0.72 0.03
163 INT242195 Positive_regulation of Negative_regulation of F10 1 0.01 0.34 0.03
164 INT199219 Negative_regulation of Positive_regulation of A2M 1 0.29 1.94 0.03
165 INT313644 Negative_regulation of Gene_expression of F10 1 0.34 1.02 0.03
166 INT284149 Negative_regulation of Localization of F2 1 0.05 0.13 0.03
167 INT213647 Gene_expression of F9 10 0.65 6.48 0
168 INT81028 Negative_regulation of F9 3 0.49 2.14 0
169 INT240052 Negative_regulation of Gene_expression of F9 2 0.04 1.32 0
170 INT141226 Regulation of F8 2 0.45 1.02 0
171 INT10137 Negative_regulation of Positive_regulation of F9 1 0.00 0 0
172 INT308127 Positive_regulation of Localization of F10 1 0.35 0.11 0
173 INT206442 Positive_regulation of Binding of PRCP 1 0.27 0 0
174 INT270550 Regulation of Negative_regulation of F8 1 0.42 1.79 0
175 INT265791 Protein_catabolism of KLKB1 1 0.07 0 0
176 INT331872 Positive_regulation of Binding of VWF 1 0.12 0 0
177 INT316083 Regulation of Regulation of F2 1 0.44 1.55 0
178 INT325340 Positive_regulation of Binding of F10 1 0.09 0.37 0
179 INT128758 Regulation of Gene_expression of VWF 1 0.03 0 0
180 INT106285 Positive_regulation of Regulation of VWF 1 0.10 0 0
181 INT326467 Regulation of Gene_expression of F12 1 0.44 0.6 0
182 INT265786 Positive_regulation of Positive_regulation of KLKB1 1 0.04 0.24 0
183 INT265789 Negative_regulation of Protein_catabolism of KLKB1 1 0.03 0 0
184 INT306376 Positive_regulation of GP1BA 1 0.05 0 0
185 INT312580 Negative_regulation of Localization of F8 1 0.11 0.24 0
186 INT328285 Negative_regulation of Localization of SERPING1 1 0.37 0.95 0
187 INT265782 Regulation of Gene_expression of KLKB1 1 0.04 0 0
188 INT204875 Negative_regulation of Positive_regulation of SERPING1 1 0.42 0.1 0
189 INT250579 Transcription of F12 1 0.62 0.77 0
190 INT345401 Localization of F8 1 0.60 0 0
191 INT265506 Binding of F9 1 0.03 0.38 0
192 INT331870 Positive_regulation of Localization of F8 1 0.46 1.24 0
193 INT308128 Localization of F10 1 0.52 0.88 0
194 INT351657 Protein_catabolism of PRCP 1 0.01 0.63 0
195 INT331871 Phosphorylation of F8 1 0.75 0 0
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