GO:0007600

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Name sensory perception
Categary Process
Go Slim No
Go Link GO:0007600
Unique Molecular Interactions 253
Total Molecular Interactions 379
Total Single Events 2481
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sensory perception. They are ordered first by their pain relevance and then by number of times they were reported for sensory perception. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
2 INT51205 Binding of OPRK1 and PDYN 7 0.00 2.01 7.8
3 INT125407 Binding of OPRL1 and PTPRM 1 0.03 0.72 4.67
4 INT64480 Binding of OPRL1 and PNOC 2 0.33 0.23 4.38
5 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
6 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63
7 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
8 INT108473 Binding of ADCYAP1 and PNOC 1 0.32 0.64 3.41
9 INT108472 Binding of NOS1 and PNOC 1 0.32 0.64 3.27
10 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
11 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
12 INT51202 Positive_regulation of Binding of OPRK1 and PDYN 3 0.00 0.63 3.1
13 INT114126 Binding of APLNR and OPRL1 1 0.01 0.47 2.85
14 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
15 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
16 INT88730 Binding of OPRM1 and Mop3 1 0.00 0 2.34
17 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 0.00 0.08 2.31
18 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
19 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13
20 INT133946 Binding of DNM2 and OPRK1 1 0.11 0 2.1
21 INT51198 Positive_regulation of Binding of OPRM1 and PDYN 2 0.18 0.3 2.08
22 INT51199 Binding of OPRM1 and PDYN 2 0.13 0.3 2.08
23 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
24 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
25 INT113572 Binding of DMRT1 and OPRM1 1 0.01 0 1.9
26 INT72468 Negative_regulation of Binding of OPRL1 and PNOC 1 0.40 0 1.83
27 INT167319 Binding of OPRM1 and PCSK2 1 0.22 0.63 1.77
28 INT167320 Binding of CPE and OPRM1 1 0.14 0.63 1.77
29 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
30 INT149491 PNOC Negative_regulation of Gene_expression of CD14 1 0.40 0.37 1.76
31 INT157524 Binding of GRM5 and OPRM1 1 0.36 0 1.74
32 INT69666 Binding of OPRL1 and Pnoc 2 0.45 0.06 1.66
33 INT134742 Binding of OPRM1 and SV2A 1 0.33 0.18 1.64
34 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
35 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
36 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
37 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
38 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
39 INT141676 OPRM1 Positive_regulation of Ltp 1 0.04 0 1.46
40 INT141675 OPRM1 Positive_regulation of Negative_regulation of Ltp 1 0.04 0 1.46
41 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
42 INT161858 OPRM1 Positive_regulation of GRIN1 1 0.50 0.12 1.45
43 INT128915 PENK Regulation of Gene_expression of OPRM1 1 0.22 0.07 1.43
44 INT96796 ITIH4 Regulation of Gene_expression of OPRM1 2 0.20 0.89 1.41
45 INT133937 Binding of OPRK1 and ARFGEF1 1 0.01 0 1.39
46 INT128914 COMT Regulation of OPRM1 1 0.39 0.07 1.39
47 INT51203 Binding of OPRK1 and OPRM1 2 0.29 0.3 1.36
48 INT160590 CSF2 Positive_regulation of Gene_expression of OPRM1 1 0.16 0.54 1.35
49 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
50 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
51 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
52 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
53 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 1 0.13 0.54 1.35
54 INT51200 Binding of OPRM1 and PENK 2 0.17 0.23 1.31
55 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
56 INT67383 Binding of OPRK1 and Pdyn 2 0.00 0 1.25
57 INT110542 SIGMAR1 Regulation of OPRM1 1 0.04 0.33 1.25
58 INT110543 SIGMAR1 Regulation of Gene_expression of OPRM1 1 0.04 0.33 1.25
59 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
60 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
61 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
62 INT65203 OPRL1 Negative_regulation of ADCY1 1 0.19 0 1.19
63 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19
64 INT49956 OPRM1 Positive_regulation of SGCG 1 0.53 0.3 1.18
65 INT137144 ITIH4 Regulation of OPRM1 1 0.20 1.13 1.16
66 INT125696 Binding of OPRM1 and SNRNP70 1 0.06 0.99 1.15
67 INT65204 PNOC Negative_regulation of ADCY1 1 0.07 0 1.14
68 INT128515 Binding of PNOC and Pnoc 1 0.12 0.38 1.14
69 INT221183 Binding of OPRM1 and Mors1 1 0.00 0 1.12
70 INT113540 Binding of OPRM1 and Tac1 1 0.04 0.1 1.1
71 INT127133 Positive_regulation of OPRM1 Positive_regulation of Protein_catabolism of SUCLG2 1 0.20 0.2 1.1
72 INT90145 Binding of OPRL1 and OPRM1 2 0.27 0.31 1.08
73 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 1 0.40 0 1.05
74 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
75 INT97011 Binding of CALM3 and OPRM1 1 0.35 0 1.05
76 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
77 INT108413 Binding of OPRK1 and Oprd1 1 0.00 0.08 1.04
78 INT133075 TFAM Positive_regulation of Transcription of OPRM1 1 0.03 0 1.04
79 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
80 INT51204 Positive_regulation of Binding of OPRK1 and OPRM1 1 0.38 0.3 1.03
81 INT143492 OPRL1 Regulation of PNOC 1 0.05 0 0.99
82 INT86662 Ngf Regulation of SCN10A 1 0.27 1.24 0.99
83 INT1415 Binding of OPRM1 and POMC 3 0.16 0.3 0.98
84 INT51201 Negative_regulation of Binding of OPRM1 and PENK 1 0.20 0.23 0.98
85 INT157522 GRM5 Regulation of Gene_expression of OPRM1 1 0.28 0 0.97
86 INT40287 OPRM1 Positive_regulation of Negative_regulation of Prl 1 0.00 0.93 0.96
87 INT133076 STAT6 Positive_regulation of OPRM1 1 0.38 0 0.95
88 INT152388 Binding of NFKB1 and OPRM1 1 0.04 0.14 0.94
89 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
90 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
91 INT152389 Negative_regulation of Binding of NFKB1 and OPRM1 1 0.05 0.14 0.94
92 INT81329 Binding of ARRB1 and OPRK1 1 0.05 0.1 0.93
93 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
94 INT128860 NR1H4 Negative_regulation of Gene_expression of OPRM1 1 0.15 0.31 0.92
95 INT89314 Binding of CRYGS and OPRM1 1 0.07 0.08 0.91
96 INT72464 Positive_regulation of Binding of OPRL1 and PNOC 1 0.34 0 0.91
97 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
98 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
99 INT83417 Binding of OPRL1 and Oprm1 1 0.01 0 0.89
100 INT72467 Regulation of Binding of OPRL1 and PNOC 1 0.18 0 0.86
101 INT120820 Binding of ASIC3 and Dlg4 3 0.02 0.11 0.84
102 INT97012 Binding of CALM1 and OPRM1 1 0.18 0 0.82
103 INT77393 Binding of ARRB1 and OPRM1 1 0.15 0 0.82
104 INT89529 OPRM1 Regulation of CALM1 1 0.27 0 0.81
105 INT90143 Negative_regulation of Binding of OPRL1 and OPRM1 1 0.31 0.07 0.8
106 INT151807 Binding of NFATC1 and OPRM1 1 0.19 0 0.79
107 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
108 INT149495 PNOC Negative_regulation of CCL2 1 0.11 0.16 0.77
109 INT81976 Binding of GNA15 and OPRL1 1 0.02 0 0.77
110 INT133074 CNR2 Positive_regulation of Transcription of OPRM1 1 0.11 0 0.77
111 INT81977 Binding of OPRL1 and Galphaqo5 1 0.01 0 0.77
112 INT81975 Binding of OPRL1 and RASGRP1 1 0.03 0 0.76
113 INT151808 NFATC1 Positive_regulation of Positive_regulation of OPRM1 1 0.20 0 0.76
114 INT133941 ARFGEF1 Positive_regulation of OPRK1 1 0.02 0 0.76
115 INT133935 DNM2 Positive_regulation of OPRK1 1 0.11 0 0.76
116 INT96795 ITIH4 Positive_regulation of Gene_expression of OPRM1 1 0.49 0.17 0.76
117 INT128861 LBR Positive_regulation of Positive_regulation of OPRM1 1 0.19 0.36 0.75
118 INT81520 Binding of PNOC and Oprl1 1 0.24 0.1 0.75
119 INT151810 JUND Positive_regulation of Positive_regulation of OPRM1 1 0.26 0 0.74
120 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
121 INT133070 Positive_regulation of CNR2 Positive_regulation of Transcription of OPRM1 1 0.11 0 0.74
122 INT151806 TRAF3IP2 Positive_regulation of Positive_regulation of OPRM1 1 0.06 0 0.74
123 INT133938 Binding of OPRL1 and ARFGEF1 1 0.00 0 0.73
124 INT133939 Binding of OPRL1 and PDYN 1 0.00 0 0.73
125 INT120819 Binding of ASIC3 and Lin7b 1 0.01 0 0.73
126 INT133943 Binding of DNM2 and OPRL1 1 0.00 0 0.73
127 INT157541 Binding of YY1 and Regulation of Gene_expression of OPRM1 1 0.31 1.21 0.72
128 INT137139 ITIH4 Positive_regulation of OPRM1 1 0.37 0.67 0.72
129 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72
130 INT126598 Binding of BSG and OPRK1 1 0.01 0.05 0.72
131 INT120818 Lin7b Positive_regulation of ASIC3 1 0.01 0 0.71
132 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
133 INT82759 Binding of IGHG3 and OPRM1 2 0.06 0 0.7
134 INT123869 Binding of GNAS and OPRK1 1 0.00 0.37 0.7
135 INT107741 Binding of OPRM1 and Pld2 1 0.01 0 0.69
136 INT130717 Binding of OPRM1 and Positive_regulation of Localization of CCL2 1 0.00 0.72 0.68
137 INT117677 Binding of MATN3 and OPRL1 1 0.26 0.07 0.68
138 INT86638 POMC Negative_regulation of Gene_expression of OPRM1 1 0.34 0.33 0.68
139 INT30503 OPRM1 Regulation of Localization of Prl 1 0.00 0 0.67
140 INT169215 Binding of OPRM1 and CARTPT 1 0.00 0.22 0.67
141 INT169219 Binding of OPRM1 and Coc 1 0.01 0.22 0.67
142 INT137140 HIVEP1 Regulation of Gene_expression of OPRM1 1 0.25 0.69 0.66
143 INT121272 PNOC Negative_regulation of Positive_regulation of TRPV1 1 0.27 0 0.66
144 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
145 INT101716 JUND Regulation of Regulation of OPRM1 1 0.09 0.06 0.65
146 INT111014 Binding of OPRL1 and Oprd1 1 0.02 0 0.64
147 INT322385 PPBP Negative_regulation of Positive_regulation of OPRM1 1 0.00 0 0.64
148 INT137145 HIVEP1 Regulation of OPRM1 1 0.10 0.7 0.64
149 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
150 INT30502 Negative_regulation of OPRM1 Negative_regulation of Gh 1 0.00 0 0.63
151 INT253165 SCN10A Positive_regulation of OVGP1 1 0.06 1.34 0.61
152 INT101718 PLAT Positive_regulation of Transcription of OPRM1 1 0.22 0.06 0.61
153 INT113962 OPRM1 Regulation of CREB1 1 0.39 0.31 0.6
154 INT126951 PNOC Positive_regulation of OPRM1 1 0.21 0.06 0.6
155 INT137138 ITIH4 Positive_regulation of Positive_regulation of OPRM1 1 0.42 0.55 0.59
156 INT161387 Binding of PNOC and GTPBP4 1 0.03 1.05 0.59
157 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
158 INT159125 Binding of OPRM1 and SUGT1 1 0.03 0.31 0.57
159 INT210830 OPRM1 Negative_regulation of ADCY1 1 0.00 0.06 0.55
160 INT99486 OPRM1 Positive_regulation of MAPK3 1 0.22 0 0.55
161 INT137143 HIVEP1 Positive_regulation of OPRM1 1 0.15 0.43 0.52
162 INT106392 ADRBK1 Regulation of Negative_regulation of OPRL1 1 0.27 0.06 0.52
163 INT113241 TRAF3IP2 Regulation of Transcription of OPRM1 1 0.05 0.82 0.52
164 INT113243 TNF Positive_regulation of Transcription of OPRM1 1 0.23 0.84 0.51
165 INT318472 CA2 Regulation of OPRM1 1 0.17 0 0.51
166 INT86264 OPRK1 Negative_regulation of Gene_expression of HIVEP1 1 0.33 1.76 0.51
167 INT93265 Binding of ADCY1 and OPRL1 1 0.13 0.17 0.51
168 INT144456 Binding of GPM6A and OPRM1 1 0.07 0 0.5
169 INT98116 Gdnf Regulation of SCN10A 1 0.03 0.39 0.5
170 INT115800 Positive_regulation of HRASLS Positive_regulation of Positive_regulation of OPRM1 1 0.11 0 0.49
171 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49
172 INT81331 ADRBK1 Regulation of OPRK1 1 0.03 0.09 0.48
173 INT150536 OPRM1 Positive_regulation of Positive_regulation of IL6 1 0.04 0.38 0.48
174 INT150537 OPRM1 Positive_regulation of Negative_regulation of IL6 1 0.04 0.38 0.48
175 INT150539 OPRM1 Positive_regulation of IL6 1 0.04 0.38 0.48
176 INT150534 OPRM1 Positive_regulation of TNF 1 0.03 0.38 0.48
177 INT150535 OPRM1 Positive_regulation of Positive_regulation of TNF 1 0.08 0.38 0.48
178 INT112843 Binding of OPRK1 and Nfatc4 1 0.00 0 0.48
179 INT81330 ARRB1 Regulation of OPRK1 1 0.04 0.09 0.47
180 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
181 INT26338 Binding of OPRM1 and Prl 1 0.02 0.37 0.47
182 INT89647 OPRM1 Regulation of ADCY1 1 0.09 0.09 0.47
183 INT117703 OPRK1 Positive_regulation of Positive_regulation of JUN 1 0.01 0.08 0.47
184 INT81333 Binding of OPRK1 and SNORD50A 1 0.07 0.09 0.46
185 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
186 INT116934 OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
187 INT81335 Negative_regulation of Binding of OPRK1 and SNORD50A 1 0.08 0.1 0.46
188 INT116937 Positive_regulation of OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
189 INT116929 OPRK1 Positive_regulation of JUN 1 0.28 0.15 0.46
190 INT88215 Binding of PNOC and Pnoc 1 0.01 0.07 0.46
191 INT98119 Gdnf Regulation of SCN10A 1 0.01 0.34 0.45
192 INT46008 OPRM1 Regulation of Localization of PRL 1 0.14 0 0.44
193 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43
194 INT116931 OPRK1 Regulation of MAPK8 1 0.31 0.07 0.43
195 INT66196 OPRK1 Negative_regulation of Oprd1 1 0.00 0 0.43
196 INT113537 Binding of OPRM1 and TACR1 1 0.01 0.1 0.42
197 INT80233 Positive_regulation of OPRM1 Positive_regulation of GNAI1 1 0.23 0 0.41
198 INT27451 OPRM1 Positive_regulation of Localization of Lhb 1 0.01 0.1 0.41
199 INT80232 OPRM1 Positive_regulation of GNAI1 1 0.23 0 0.41
200 INT18125 Binding of OPRM1 and Penk 1 0.54 0 0.4

Single Events

The table below shows the top 100 pain related interactions that have been reported for sensory perception. They are ordered first by their pain relevance and then by number of times they were reported in sensory perception. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36
2 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28
3 INT4658 Binding of OPRM1 188 0.48 25.96 136.24
4 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37
5 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57
6 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18
7 INT69484 Positive_regulation of Gene_expression of OPRM1 75 0.70 12.86 52.27
8 INT10304 Binding of OPRK1 89 0.48 9.28 49.42
9 INT29105 Positive_regulation of OPRK1 68 0.70 7.06 44.69
10 INT1564 Localization of OPRM1 41 0.80 8.03 44.67
11 INT77407 Regulation of Gene_expression of OPRM1 51 0.62 12.58 35.75
12 INT7845 Regulation of OPRK1 44 0.62 4.54 30.49
13 INT69483 Transcription of OPRM1 45 0.72 7.31 30.22
14 INT49431 Phosphorylation of OPRM1 31 0.82 2.2 29.09
15 INT12475 Gene_expression of OPRL1 35 0.77 3.63 23.11
16 INT40811 Binding of OPRL1 26 0.48 2.76 18.68
17 INT32753 Positive_regulation of Positive_regulation of OPRM1 19 0.62 3.3 16.73
18 INT81087 Gene_expression of ASIC3 30 0.75 13.62 16.54
19 INT78749 Gene_expression of SCN10A 25 0.75 9.23 16.5
20 INT76863 Negative_regulation of Gene_expression of OPRM1 21 0.57 6.56 13.69
21 INT80883 Positive_regulation of Phosphorylation of OPRM1 13 0.69 1.03 13.65
22 INT20881 Negative_regulation of OPRK1 20 0.43 3.73 13.37
23 INT86646 Positive_regulation of SCN10A 71 0.69 50.61 13.24
24 INT72804 Negative_regulation of OPRL1 16 0.43 1.79 12.14
25 INT64484 Binding of PNOC 12 0.33 5.51 10.86
26 INT78556 Gene_expression of PNOC 11 0.76 2.93 10.58
27 INT33957 Positive_regulation of OPRL1 14 0.68 2.89 9.72
28 INT83674 Negative_regulation of SCN10A 14 0.59 7.28 9.65
29 INT33209 Positive_regulation of Binding of OPRM1 8 0.68 0.63 8.95
30 INT50191 Positive_regulation of Gene_expression of OPRK1 9 0.67 3.44 7.91
31 INT11568 Gene_expression of ADORA2A 14 0.73 1.51 7.79
32 INT31060 Negative_regulation of Binding of OPRM1 12 0.37 2.65 7.75
33 INT101721 Positive_regulation of Transcription of OPRM1 8 0.48 1.22 7.74
34 INT65206 Regulation of PNOC 8 0.38 1.61 7.43
35 INT121815 Regulation of Positive_regulation of OPRM1 7 0.62 0.75 7.36
36 INT12699 Transcription of OPRK1 11 0.52 0.08 6.66
37 INT42832 Negative_regulation of Positive_regulation of OPRM1 6 0.36 0.96 6.35
38 INT97600 Regulation of Transcription of OPRM1 8 0.52 1.14 6.21
39 INT27118 Regulation of Binding of OPRM1 10 0.62 1.18 5.97
40 INT76741 Localization of OPRK1 7 0.68 0.22 5.9
41 INT29051 Regulation of OPRL1 6 0.60 1.29 5.81
42 INT92280 Transcription of OPRL1 10 0.70 1.36 5.68
43 INT110545 Regulation of Regulation of OPRM1 7 0.42 1.68 5.67
44 INT93165 Gene_expression of TRPV2 32 0.78 12.49 5.62
45 INT32979 Positive_regulation of Localization of OPRM1 5 0.50 0 5.54
46 INT74182 Positive_regulation of Binding of OPRK1 8 0.49 1.39 5.25
47 INT29354 Regulation of Binding of OPRK1 7 0.60 1.72 5.04
48 INT42833 Positive_regulation of Negative_regulation of OPRM1 6 0.48 0.12 4.95
49 INT72474 Positive_regulation of PNOC 9 0.68 1.76 4.84
50 INT86647 Localization of SCN10A 8 0.78 3.88 4.27
51 INT102363 Negative_regulation of Positive_regulation of OPRK1 7 0.43 0.99 4.25
52 INT77515 Positive_regulation of ASIC3 12 0.67 3.67 4.19
53 INT80882 Negative_regulation of Phosphorylation of OPRM1 4 0.45 0.21 3.68
54 INT66782 Negative_regulation of Gene_expression of OPRK1 4 0.28 1.42 3.41
55 INT72472 Positive_regulation of Gene_expression of OPRL1 4 0.68 0.07 3.39
56 INT13347 Regulation of Negative_regulation of OPRM1 5 0.45 0.64 3.38
57 INT101368 Positive_regulation of Gene_expression of ASIC3 6 0.32 2.61 3.06
58 INT80521 Negative_regulation of Binding of OPRK1 4 0.43 0.8 2.93
59 INT106401 Negative_regulation of Gene_expression of OPRL1 3 0.40 0.07 2.92
60 INT52166 Positive_regulation of Positive_regulation of OPRK1 2 0.57 0.48 2.74
61 INT113450 Regulation of ASIC3 4 0.21 1.81 2.73
62 INT85597 Positive_regulation of Localization of OPRK1 2 0.45 0 2.65
63 INT77213 Transcription of ADORA2A 1 0.69 0 2.55
64 INT120814 Negative_regulation of ASIC3 10 0.28 0.99 2.53
65 INT101369 Binding of ASIC3 3 0.32 1.11 2.5
66 INT64062 Negative_regulation of Regulation of OPRM1 2 0.41 0.3 2.48
67 INT121274 Negative_regulation of PNOC 4 0.43 0.22 2.16
68 INT108475 Transcription of PNOC 1 0.52 0.35 2.08
69 INT32980 Positive_regulation of Regulation of OPRM1 2 0.45 0 1.98
70 INT36400 Regulation of SCN10A 7 0.62 2.73 1.97
71 INT142684 Protein_catabolism of OPRM1 2 0.66 0.48 1.81
72 INT99450 Regulation of Gene_expression of OPRL1 1 0.40 0.43 1.55
73 INT115804 Regulation of Localization of OPRM1 2 0.33 0.12 1.33
74 INT67450 Negative_regulation of Localization of OPRM1 2 0.06 0.24 1.26
75 INT106409 Localization of OPRL1 2 0.73 0.27 1.26
76 INT160753 Negative_regulation of Gene_expression of PNOC 1 0.36 0.27 1.17
77 INT119124 Positive_regulation of ADORA2A 4 0.35 0.96 1.14
78 INT84146 Negative_regulation of Negative_regulation of SCN10A 1 0.42 1.11 1.12
79 INT216849 Binding of ADORA2A 2 0.05 0 1.11
80 INT35786 Negative_regulation of Negative_regulation of OPRM1 2 0.33 0.91 1.1
81 INT86649 Binding of SCN10A 2 0.36 1.85 1.1
82 INT106405 Positive_regulation of Positive_regulation of OPRL1 2 0.49 0.31 1.07
83 INT119125 Regulation of ADORA2A 2 0.31 0 1.01
84 INT118924 Positive_regulation of Regulation of OPRK1 2 0.68 0 1
85 INT108474 Localization of PNOC 1 0.73 0.14 0.96
86 INT77215 Localization of ADORA2A 2 0.77 0 0.91
87 INT92428 Regulation of Myo7a 2 0.44 1.23 0.91
88 INT72471 Negative_regulation of Binding of PNOC 1 0.23 0 0.91
89 INT83672 Regulation of Negative_regulation of SCN10A 1 0.44 0.37 0.89
90 INT121687 Positive_regulation of Negative_regulation of OPRK1 1 0.49 0 0.79
91 INT110504 Negative_regulation of Negative_regulation of OPRL1 1 0.37 0.22 0.76
92 INT90146 Negative_regulation of Binding of OPRL1 1 0.58 0.07 0.74
93 INT160754 Negative_regulation of Transcription of OPRL1 1 0.43 0.13 0.73
94 INT126963 Phosphorylation of PNOC 1 0.61 0.07 0.72
95 INT142953 Positive_regulation of Gene_expression of TRPV2 2 0.70 5.56 0.64
96 INT121273 Negative_regulation of Negative_regulation of PNOC 1 0.43 0 0.6
97 INT118923 Protein_catabolism of OPRK1 1 0.00 0 0.59
98 INT161389 Regulation of Binding of PNOC 1 0.21 1.06 0.59
99 INT71672 Phosphorylation of OPRK1 2 0.12 0 0.56
100 INT81034 Protein_catabolism of PNOC 1 0.17 0.19 0.56
101 INT40810 Positive_regulation of Binding of OPRL1 1 0.47 0 0.52
102 INT70840 Regulation of Positive_regulation of OPRK1 1 0.09 0.09 0.5
103 INT130967 Regulation of Localization of ASIC3 1 0.21 0.24 0.42
104 INT130968 Localization of ASIC3 1 0.53 0.24 0.42
105 INT142491 Positive_regulation of Positive_regulation of SCN10A 6 0.61 3.48 0.35
106 INT119123 Regulation of Positive_regulation of ADORA2A 1 0.31 0 0.35
107 INT146074 Regulation of Transcription of OPRK1 1 0.26 0 0.34
108 INT118439 Transcription of TRPV2 2 0.71 0.26 0.29
109 INT97025 Positive_regulation of Positive_regulation of ASIC3 1 0.09 0.18 0.27
110 INT327817 Negative_regulation of ADORA2A 1 0.17 1.83 0.27
111 INT157905 Binding of TRPV2 1 0.31 0.91 0.25
112 INT118444 Positive_regulation of Transcription of TRPV2 1 0.44 0.26 0.21
113 INT136279 Positive_regulation of TRPV2 1 0.50 0 0.2
114 INT74608 Negative_regulation of Positive_regulation of OPRL1 1 0.35 0.26 0.19
115 INT67771 Regulation of Positive_regulation of OPRL1 1 0.03 0.09 0.18
116 INT92279 Regulation of Transcription of OPRL1 1 0.44 0 0.17
117 INT181237 Negative_regulation of Negative_regulation of OPRK1 1 0.07 0 0.14
118 INT124527 Positive_regulation of Myo7a 1 0.00 0.15 0.1
119 INT168521 Localization of Myo7a 1 0.18 0.17 0.1
120 INT92277 Positive_regulation of Transcription of OPRL1 1 0.49 0 0.07
121 INT251741 Regulation of Gene_expression of SCN10A 1 0.45 1.08 0.06
122 INT251742 Regulation of Positive_regulation of SCN10A 1 0.27 1.37 0.06
123 INT93164 Localization of TRPV2 2 0.74 0.07 0.05
124 INT328234 Negative_regulation of Positive_regulation of SCN10A 1 0.36 0.52 0
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