GO:0007623

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Name circadian rhythm
Categary Process
Go Slim No
Go Link GO:0007623
Unique Molecular Interactions 1140
Total Molecular Interactions 1681
Total Single Events 17937
Pain Genes Associated 67

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for circadian rhythm. They are ordered first by their pain relevance and then by number of times they were reported for circadian rhythm. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18
2 INT31439 Penk Positive_regulation of Localization of Prl 8 0.55 0.23 6.24
3 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44
4 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96
5 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39
6 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29
7 INT1313 Pomc Positive_regulation of Prl 7 0.35 0 4.19
8 INT31440 Penk Positive_regulation of Prl 7 0.76 0 4.1
9 INT2169 Penk Regulation of Localization of Prl 6 0.48 0 4.03
10 INT107801 Ugt1a5 Positive_regulation of Localization of Prl 3 0.76 1 3.9
11 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76
12 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
13 INT3434 Vip Positive_regulation of Localization of Prl 6 0.76 0.16 3.21
14 INT40660 Pdyn Positive_regulation of Localization of Prl 1 0.27 0 3.01
15 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
16 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
17 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
18 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
19 INT249013 Gabrg1 Negative_regulation of Per2 1 0.34 0.07 2.31
20 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
21 INT45423 Avp Positive_regulation of Localization of Prl 4 0.67 1.37 1.98
22 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
23 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
24 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
25 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
26 INT117269 Binding of Avp and Prl 1 0.25 0.47 1.8
27 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
28 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
29 INT249005 Gabrg1 Positive_regulation of Per2 1 0.39 0 1.7
30 INT32482 Ghrh Positive_regulation of Prl 3 0.18 0.26 1.62
31 INT335405 Binding of Arntl and Npas2 1 0.28 1.82 1.61
32 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
33 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
34 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
35 INT6768 Oprl1 Regulation of Localization of Prl 2 0.12 0 1.55
36 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
37 INT14375 Gal Positive_regulation of Localization of Prl 1 0.77 0 1.48
38 INT44504 Mt1a Positive_regulation of Prl 1 0.37 0 1.48
39 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
40 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
41 INT87812 Penk Regulation of Prl 1 0.16 0 1.34
42 INT777 Prss12 Positive_regulation of Prl 1 0.19 0 1.33
43 INT34393 Oprd1 Negative_regulation of Adcy1 1 0.36 0 1.27
44 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
45 INT52205 Prl Positive_regulation of Gene_expression of Penk 1 0.52 0.15 1.25
46 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
47 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25
48 INT249014 Gabrg1 Regulation of Per2 1 0.31 0 1.24
49 INT63864 Oprd1 Regulation of Localization of Prl 2 0.16 0 1.23
50 INT45891 Tyms Positive_regulation of Localization of Acot1 1 0.02 0 1.23
51 INT70028 LTA Regulation of PRF1 1 0.02 1.42 1.21
52 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
53 INT70045 IL12A Regulation of Negative_regulation of PRF1 1 0.04 1.42 1.21
54 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
55 INT70042 LTA Regulation of Negative_regulation of PRF1 1 0.02 1.42 1.21
56 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
57 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
58 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
59 INT70044 IL12A Regulation of PRF1 1 0.04 1.42 1.21
60 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
61 INT65203 OPRL1 Negative_regulation of ADCY1 1 0.19 0 1.19
62 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19
63 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
64 INT249002 Gabrg1 Positive_regulation of Protein_catabolism of Per1 1 0.35 0.09 1.15
65 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14
66 INT65204 PNOC Negative_regulation of ADCY1 1 0.07 0 1.14
67 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
68 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
69 INT25036 TRH Regulation of Prl 4 0.27 1.75 1.09
70 INT40451 Cck Regulation of Prl 1 0.49 0 1.09
71 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
72 INT34900 Trh Positive_regulation of Localization of Prl 1 0.05 0 1.09
73 INT17414 TRH Positive_regulation of Prl 4 0.47 0 1.07
74 INT77737 Pnoc Positive_regulation of Localization of Prl 3 0.55 0 1.07
75 INT39485 Prl Negative_regulation of Localization of Gnrh1 2 0.40 0 1.06
76 INT58745 CPP Positive_regulation of Localization of Prl 1 0.01 0.92 1.06
77 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
78 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
79 INT139752 Ubqln1 Regulation of Localization of Prl 1 0.05 0 1.04
80 INT200307 Rest Negative_regulation of Rorb 1 0.00 0.1 1.03
81 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
82 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
83 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
84 INT52562 Lhb Positive_regulation of Prl 3 0.00 1.09 1.02
85 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
86 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
87 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
88 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
89 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
90 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
91 INT320021 Prkaca Regulation of Positive_regulation of Kcnma1 1 0.00 0.54 1
92 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
93 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
94 INT53052 ANTXRL Negative_regulation of Negative_regulation of ADCY1 1 0.01 0.66 0.99
95 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
96 INT13372 Prl Regulation of LH 2 0.25 0.09 0.98
97 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
98 INT128602 Binding of Kcnma1 and Gtf2ird2 1 0.00 0 0.97
99 INT86960 ADRA1D Negative_regulation of Prl 1 0.00 0 0.97
100 INT136420 Binding of DeltaFosB and Rorb 1 0.03 0.66 0.97
101 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
102 INT40287 OPRM1 Positive_regulation of Negative_regulation of Prl 1 0.00 0.93 0.96
103 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
104 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
105 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
106 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
107 INT88583 Hal Positive_regulation of Prl 1 0.15 0.44 0.95
108 INT60827 Ddc Positive_regulation of Localization of Abat 1 0.12 0.34 0.94
109 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
110 INT199396 Prok2 Regulation of Trpv1 1 0.43 1.23 0.94
111 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
112 INT60828 Ddc Positive_regulation of Abat 1 0.13 0.34 0.93
113 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
114 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
115 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
116 INT55204 Prl Positive_regulation of Localization of Dbi 1 0.02 0 0.91
117 INT46972 Amt Positive_regulation of Localization of Prl 1 0.37 0.2 0.91
118 INT199392 Pklr Positive_regulation of Prok2 1 0.34 1.3 0.91
119 INT333303 Zic2 Regulation of Gene_expression of Slc6a4 1 0.60 0.47 0.91
120 INT32713 Prl Regulation of Localization of Gnrh1 3 0.42 0.17 0.9
121 INT52114 Oprd1 Regulation of ADCY1 2 0.05 0.46 0.9
122 INT199393 Prok2 Positive_regulation of Prokr1 1 0.48 1.3 0.9
123 INT28921 Adra2a Positive_regulation of Localization of Prl 1 0.24 0 0.9
124 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
125 INT112642 Positive_regulation of Kcnma1 Positive_regulation of Nav1 1 0.02 0 0.89
126 INT61048 Oprm1 Positive_regulation of Localization of Prl 1 0.16 0 0.88
127 INT61045 Oprm1 Positive_regulation of Prl 1 0.16 0 0.88
128 INT199389 Prok2 Positive_regulation of Localization of Il1f5 1 0.05 1.17 0.88
129 INT31950 PIF1 Positive_regulation of Localization of Prl 1 0.06 0 0.87
130 INT61410 CTS Positive_regulation of Prl 1 0.02 1.49 0.87
131 INT239533 Binding of MTNR1A and NCOR2 1 0.01 0.53 0.87
132 INT200308 Binding of Rest and Rorb 1 0.00 0 0.87
133 INT199391 Pklr Positive_regulation of Prokr1 1 0.31 1.28 0.87
134 INT52390 OPRD1 Regulation of ADCY1 1 0.09 0.13 0.86
135 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 0.12 0.27 0.86
136 INT26529 Prl Regulation of Avp 1 0.08 0.26 0.85
137 INT17416 TRH Positive_regulation of Localization of Prl 1 0.47 0 0.85
138 INT36008 Negative_regulation of Binding of Drd2 and Prl 1 0.01 2.11 0.85
139 INT26528 Prl Regulation of Oxt 1 0.26 0.26 0.85
140 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
141 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84
142 INT80877 Negative_regulation of PCDHB17 Negative_regulation of ADCY1 1 0.01 0.08 0.84
143 INT80878 PCDHB17 Negative_regulation of ADCY1 1 0.01 0.08 0.84
144 INT3432 Vip Positive_regulation of Prl 2 0.45 0 0.82
145 INT335404 Binding of Arntl and Hspg2 1 0.06 0.93 0.82
146 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
147 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
148 INT190182 JUN Positive_regulation of MMP12 1 0.34 0.08 0.8
149 INT105249 Cyb5b Positive_regulation of Localization of Prl 1 0.04 0 0.79
150 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
151 INT258798 Binding of NR3C1 and HSP90AA1 1 0.01 1.09 0.78
152 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
153 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77
154 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
155 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77
156 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76
157 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76
158 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
159 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 0.18 0.39 0.76
160 INT18099 POMC Positive_regulation of Binding of Prl 1 0.00 0 0.76
161 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
162 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76
163 INT65593 CALCA Negative_regulation of Positive_regulation of ADCY1 1 0.23 0.07 0.76
164 INT90123 Jun Positive_regulation of Gene_expression of Fos 1 0.47 0.39 0.76
165 INT52206 Prl Regulation of Gene_expression of Penk 2 0.46 0.66 0.75
166 INT169769 Mir16-1 Regulation of Slc6a4 1 0.24 0 0.74
167 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
168 INT333296 Gtf3a Regulation of Gene_expression of Slc6a4 1 0.01 0 0.74
169 INT190986 Per1 Positive_regulation of Scn2a1 1 0.17 0 0.74
170 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
171 INT190979 Per2 Positive_regulation of Scn2a1 1 0.20 0 0.74
172 INT44502 Regulation of Mt1a Positive_regulation of Prl 1 0.14 0 0.74
173 INT44503 Cubn Positive_regulation of Prl 1 0.18 0 0.74
174 INT190169 Regulation of JUN Positive_regulation of Localization of MMP12 1 0.30 0.07 0.74
175 INT17528 Prl Regulation of Gh 2 0.28 1.28 0.73
176 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
177 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
178 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
179 INT45946 Nts Negative_regulation of Prl 2 0.50 0 0.71
180 INT9290 Pomc Regulation of Prl 2 0.09 0.69 0.71
181 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
182 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
183 INT12711 POMC Regulation of Prl 1 0.04 1.25 0.7
184 INT12022 Crh Positive_regulation of Localization of Prl 1 0.02 0.14 0.7
185 INT782 Tf Positive_regulation of Prl 1 0.43 0 0.7
186 INT46656 Mtr Regulation of Prl 1 0.05 0 0.7
187 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
188 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
189 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
190 INT55205 Prl Positive_regulation of Localization of Crh 1 0.47 0 0.69
191 INT55209 Prl Positive_regulation of Crh 1 0.51 0 0.69
192 INT66581 Binding of JUN and Rare2 1 0.00 0.07 0.69
193 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
194 INT249018 Gabrg1 Regulation of Localization of Per2 1 0.35 0 0.69
195 INT99937 Ddc Regulation of Transcription of Qrfp 1 0.02 0 0.69
196 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69
197 INT42780 Negative_regulation of Scn4a Negative_regulation of Positive_regulation of Prl 1 0.11 0 0.69
198 INT32715 Prl Regulation of Localization of LH 2 0.34 0.09 0.68
199 INT74727 Binding of Slc6a4 and Hpic1 1 0.00 0.49 0.68
200 INT199394 Prok2 Regulation of Positive_regulation of Prokr1 1 0.28 0.89 0.68

Single Events

The table below shows the top 100 pain related interactions that have been reported for circadian rhythm. They are ordered first by their pain relevance and then by number of times they were reported in circadian rhythm. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT158 Localization of Prl 2431 0.81 378.96 952.2
2 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82
3 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78
4 INT162 Regulation of Prl 794 0.62 165.01 322.24
5 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66
6 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24
7 INT528 Gene_expression of Prl 693 0.78 217.18 192.2
8 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8
9 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96
10 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
11 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
12 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9
13 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
14 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
15 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
16 INT1977 Negative_regulation of Positive_regulation of Prl 98 0.59 17.06 47.88
17 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06
18 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36
19 INT2296 Positive_regulation of Gene_expression of Prl 137 0.70 36.96 35.39
20 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
21 INT47764 Binding of Jun 106 0.48 22.62 31.39
22 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56
23 INT67 Negative_regulation of Ddc 66 0.59 15.34 28.96
24 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23
25 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84
26 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
27 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
28 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
29 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
30 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19
31 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
32 INT127435 Gene_expression of Per1 89 0.77 13.94 22.31
33 INT6230 Localization of Ddc 40 0.79 13.11 20.88
34 INT1512 Binding of Prl 73 0.48 26.22 20.63
35 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
36 INT160 Regulation of Positive_regulation of Prl 37 0.62 7.56 20.09
37 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
38 INT1975 Regulation of Regulation of Prl 32 0.59 5.78 18.53
39 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
40 INT871 Negative_regulation of Gene_expression of Prl 53 0.58 18.89 17.79
41 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
42 INT12617 Regulation of ADCY1 41 0.61 7.38 15.94
43 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
44 INT149816 Gene_expression of Prok2 21 0.78 18.99 15.68
45 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
46 INT75908 Regulation of LEP 77 0.60 60.16 15.19
47 INT128319 Gene_expression of Per2 105 0.78 14.69 15.13
48 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
49 INT17593 Regulation of Jun 37 0.60 5.5 14.35
50 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
51 INT73641 Regulation of Lep 45 0.62 26.2 12.59
52 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28
53 INT21987 Positive_regulation of Rorb 30 0.33 12.7 12.24
54 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23
55 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
56 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93
57 INT128054 Gene_expression of Per1 15 0.61 2.12 11.84
58 INT118755 Gene_expression of Per2 12 0.68 2.81 11.41
59 INT40486 Positive_regulation of Positive_regulation of ADCY1 20 0.48 4.29 11.33
60 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
61 INT52233 Transcription of Jun 37 0.66 6.39 11.15
62 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
63 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
64 INT79656 Positive_regulation of NR3C1 14 0.68 6.38 10.83
65 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55
66 INT7458 Negative_regulation of Kcnma1 30 0.43 6.61 10.4
67 INT60198 Binding of JUN 54 0.48 11.56 10.27
68 INT9027 Positive_regulation of Ddc 24 0.66 6.04 10.19
69 INT12620 Negative_regulation of Negative_regulation of ADCY1 16 0.44 2.98 10.1
70 INT149818 Gene_expression of Clock 81 0.70 14.15 10.04
71 INT53590 Gene_expression of PRF1 33 0.58 23.46 10.02
72 INT1378 Negative_regulation of Regulation of Prl 27 0.43 9.16 9.9
73 INT53062 Gene_expression of Ddc 31 0.77 11.59 9.63
74 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45
75 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
76 INT2059 Positive_regulation of Negative_regulation of Prl 24 0.70 5.7 9.37
77 INT82082 Localization of Lep 63 0.81 26.41 8.56
78 INT75907 Binding of LEP 53 0.46 46.65 8.44
79 INT135578 Gene_expression of Prokr1 22 0.70 11.71 8.31
80 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16
81 INT54681 Negative_regulation of Positive_regulation of ADCY1 16 0.38 2.7 8.14
82 INT4563 Positive_regulation of Regulation of Prl 20 0.70 4.2 8.1
83 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
84 INT130117 Regulation of Per1 26 0.53 3.25 7.63
85 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61
86 INT47811 Positive_regulation of Localization of Ddc 11 0.69 4 7.6
87 INT66318 Gene_expression of NR3C1 26 0.76 20 7.55
88 INT4284 Regulation of Ddc 17 0.43 8.17 7.31
89 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
90 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
91 INT17041 Gene_expression of PER1 24 0.66 5.31 7.12
92 INT75497 Regulation of JUN 28 0.61 11.04 7.09
93 INT119651 Binding of Slc6a4 12 0.32 4.65 7.07
94 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
95 INT159518 Gene_expression of Clock 4 0.35 2.34 6.91
96 INT47817 Positive_regulation of Positive_regulation of Jun 21 0.66 3.7 6.83
97 INT15092 Positive_regulation of SLC6A4 17 0.67 7.32 6.7
98 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56
99 INT170385 Regulation of Clock 29 0.49 4.95 6.39
100 INT47765 Negative_regulation of Binding of Jun 21 0.43 5.05 6.38
101 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
102 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25
103 INT109714 Transcription of SLC6A4 7 0.72 3.8 6.19
104 INT116617 Phosphorylation of Rorb 15 0.07 3.43 6.12
105 INT144086 Positive_regulation of Prok2 12 0.69 9.54 6.06
106 INT38686 Binding of NR3C1 20 0.48 9.25 5.99
107 INT73649 Phosphorylation of Jun 28 0.80 11.01 5.87
108 INT91712 Localization of Prok2 11 0.80 8 5.85
109 INT52819 Negative_regulation of NR3C1 14 0.50 7.22 5.84
110 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
111 INT128045 Positive_regulation of Per1 29 0.69 5.32 5.5
112 INT196972 Regulation of Per2 23 0.62 2.22 5.46
113 INT65356 Localization of LEP 46 0.79 41.17 5.43
114 INT52814 Negative_regulation of Nr3c1 9 0.57 5.69 5.41
115 INT58489 Gene_expression of Rorb 51 0.41 4.7 5.39
116 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38
117 INT113186 Gene_expression of Prf1 46 0.53 21.06 5.32
118 INT144735 Gene_expression of DDC 8 0.75 3.21 5.31
119 INT80881 Phosphorylation of ADCY1 7 0.69 1.22 5.29
120 INT9480 Gene_expression of Jund 14 0.77 3.58 5.25
121 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23
122 INT128324 Regulation of Gene_expression of Per1 11 0.61 1.95 5.22
123 INT119711 Positive_regulation of Slc6a4 16 0.69 4.44 5.21
124 INT199383 Gene_expression of Prokr2 8 0.59 7.37 5.21
125 INT47704 Regulation of Egr1 17 0.60 2.43 5.18
126 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1
127 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
128 INT13051 Regulation of Kcnma1 12 0.12 2.09 5.06
129 INT51944 Positive_regulation of Transcription of Egr1 12 0.49 1.96 4.72
130 INT58622 Gene_expression of HTR7 13 0.75 2.86 4.7
131 INT122675 Negative_regulation of Gene_expression of Slc6a4 14 0.59 6.4 4.69
132 INT48747 Positive_regulation of Dbp 7 0.24 1.28 4.69
133 INT186421 Positive_regulation of Phosphorylation of Rorb 9 0.06 1.26 4.65
134 INT52818 Localization of NR3C1 13 0.69 7.65 4.57
135 INT138216 Negative_regulation of PER1 13 0.37 9.66 4.55
136 INT97391 Binding of Lep 18 0.48 8.97 4.47
137 INT3230 Negative_regulation of Negative_regulation of Prl 9 0.43 1.85 4.41
138 INT14574 Positive_regulation of Negative_regulation of ADCY1 9 0.66 2.45 4.39
139 INT125282 Negative_regulation of Positive_regulation of NR3C1 3 0.57 0.54 4.31
140 INT139252 Negative_regulation of Per2 15 0.52 0.91 4.24
141 INT127434 Negative_regulation of Gene_expression of Per1 12 0.58 2.58 4.2
142 INT67936 Transcription of JUN 18 0.52 9.52 4.13
143 INT49712 Regulation of Nr3c1 10 0.28 5.65 4.06
144 INT79343 Positive_regulation of Slc6a4 10 0.50 1.77 4.05
145 INT204020 Negative_regulation of Gene_expression of Per2 16 0.52 2.56 3.99
146 INT204007 Localization of Per2 21 0.75 1.94 3.98
147 INT140670 Negative_regulation of Gene_expression of SLC6A4 4 0.51 2.7 3.88
148 INT73796 Localization of HTR7 8 0.78 2.39 3.87
149 INT110180 Phosphorylation of JUN 23 0.80 11.21 3.83
150 INT103021 Transcription of Slc6a4 16 0.70 3.93 3.77
151 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77
152 INT123502 Binding of Egr1 11 0.35 6.7 3.77
153 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
154 INT15776 Localization of Jun 10 0.74 3.9 3.69
155 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67
156 INT61028 Negative_regulation of Gene_expression of Jund 3 0.54 0 3.58
157 INT130119 Transcription of Per1 28 0.67 1.92 3.56
158 INT147664 Positive_regulation of Per2 19 0.63 1.07 3.56
159 INT25500 Regulation of Negative_regulation of Prl 9 0.54 1.19 3.53
160 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
161 INT61570 Positive_regulation of Transcription of Jun 10 0.35 1.62 3.45
162 INT78912 Positive_regulation of Prf1 6 0.49 1.26 3.45
163 INT87281 Localization of ADCY1 7 0.64 1.84 3.42
164 INT118761 Positive_regulation of Per2 9 0.42 0.68 3.33
165 INT99291 Transcription of Slc6a4 7 0.46 1.16 3.28
166 INT81453 Positive_regulation of Gene_expression of JUN 18 0.50 9.39 3.23
167 INT70387 Negative_regulation of Positive_regulation of Jun 14 0.37 3.76 3.23
168 INT127455 Positive_regulation of Gene_expression of Slc6a4 9 0.59 5.62 3.2
169 INT101959 Regulation of Rorb 10 0.14 5.18 3.17
170 INT100190 Regulation of Gene_expression of Slc6a4 5 0.39 1.8 3.14
171 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12
172 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
173 INT118762 Transcription of Per2 1 0.08 0 3.09
174 INT49659 Positive_regulation of Fosl2 11 0.43 1.71 3.08
175 INT13179 Regulation of Positive_regulation of ADCY1 5 0.34 0.89 3.08
176 INT62652 Binding of HTR7 9 0.47 2.79 3.06
177 INT68651 Negative_regulation of Positive_regulation of JUN 11 0.58 4.28 3.04
178 INT59309 Negative_regulation of Gene_expression of ADCY1 3 0.42 1.04 2.98
179 INT124438 Regulation of Gene_expression of Slc6a4 9 0.62 3.5 2.97
180 INT135575 Gene_expression of Prok2 7 0.73 2.51 2.95
181 INT161812 Positive_regulation of PER1 17 0.56 5.64 2.93
182 INT8095 Gene_expression of ERBB3 47 0.77 24.85 2.82
183 INT47812 Negative_regulation of Localization of Ddc 5 0.51 1.99 2.8
184 INT30815 Binding of ADCY1 7 0.36 0.21 2.79
185 INT70053 Positive_regulation of Gene_expression of PRF1 2 0.12 3.41 2.73
186 INT136522 Negative_regulation of Prokr1 9 0.58 3.53 2.71
187 INT144085 Negative_regulation of Prok2 2 0.43 2.49 2.71
188 INT351263 Binding of CLOCK 1 0.18 0.46 2.71
189 INT52911 Gene_expression of Tyms 10 0.42 2.24 2.66
190 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
191 INT5432 Regulation of Atp7b 7 0.36 0.87 2.65
192 INT80884 Positive_regulation of Phosphorylation of ADCY1 4 0.43 0.24 2.64
193 INT77250 Positive_regulation of Gene_expression of Nr3c1 4 0.44 3.32 2.64
194 INT128328 Gene_expression of Arntl 44 0.74 3.77 2.63
195 INT11426 Positive_regulation of Gene_expression of ADCY1 5 0.29 0.68 2.63
196 INT185407 Binding of PER1 13 0.42 9.32 2.6
197 INT16406 Positive_regulation of Negative_regulation of Ddc 6 0.67 0.53 2.6
198 INT3123 Localization of Tyms 6 0.78 0.85 2.6
199 INT80320 Negative_regulation of Gene_expression of Slc6a4 4 0.42 0.85 2.6
200 INT70052 Transcription of PRF1 4 0.41 3.1 2.58
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