GO:0008015

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Name blood circulation
Categary Process
Go Slim No
Go Link GO:0008015
Unique Molecular Interactions 428
Total Molecular Interactions 615
Total Single Events 4875
Pain Genes Associated 37

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for blood circulation. They are ordered first by their pain relevance and then by number of times they were reported for blood circulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87
2 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81
3 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
4 INT318998 IFNA1 Positive_regulation of Localization of CXCL10 1 0.15 2.09 2.39
5 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
6 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
7 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53
8 INT201942 DPP4 Negative_regulation of CXCL10 1 0.33 0.9 1.3
9 INT86090 SCN5A Negative_regulation of Positive_regulation of Abat 1 0.00 0 1.25
10 INT105240 POMC Positive_regulation of Gene_expression of CXCL10 1 0.07 1.18 1.16
11 INT299985 BDKRB2 Regulation of Gene_expression of BDKRB1 1 0.21 0.75 1.16
12 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14
13 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14
14 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
15 INT221 Chd7 Negative_regulation of Th 1 0.02 0 1.04
16 INT299986 BDKRB2 Regulation of Gene_expression of SPANXB1 1 0.29 0.51 1.02
17 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97
18 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97
19 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
20 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
21 INT182208 Binding of CXCR2 and CXCL12 1 0.29 1.26 0.95
22 INT12373 SCN5A Negative_regulation of Cpe 1 0.00 0 0.94
23 INT139330 Binding of SGCG and Stat1 1 0.37 0.75 0.94
24 INT182198 Binding of CXCR5 and CXCL12 1 0.33 1.25 0.94
25 INT182209 Binding of CXCL12 and CXCL13 1 0.30 1.24 0.93
26 INT156989 LPA Positive_regulation of Gene_expression of EFNB1 1 0.00 0.91 0.92
27 INT306823 Binding of E2F4 and GOPC 1 0.06 0.23 0.91
28 INT136172 NPY Negative_regulation of Positive_regulation of Drd1a 1 0.21 0 0.91
29 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
30 INT74872 Igh-Dex Positive_regulation of Chd7 1 0.01 0.5 0.89
31 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
32 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
33 INT167947 Binding of STAT1 and Oprm1 1 0.00 0 0.86
34 INT306831 Positive_regulation of Binding of E2F4 and NOLC1 1 0.10 0.46 0.85
35 INT306826 Binding of E2F4 and NOLC1 1 0.08 0.41 0.84
36 INT299990 BDKRB2 Positive_regulation of TRPV1 1 0.43 0.74 0.84
37 INT94331 IFNG Positive_regulation of CXCL10 4 0.11 1.31 0.82
38 INT16507 Binding of LPA and Crp 1 0.00 0.78 0.78
39 INT346133 RAMP2 Regulation of ADM 1 0.13 2.06 0.78
40 INT16494 Binding of LPA and Serpinf2 1 0.00 0.78 0.78
41 INT351364 LPA Positive_regulation of Trpv1 1 0.02 1.15 0.78
42 INT16492 Positive_regulation of Binding of LPA and Serpinf2 1 0.00 0.78 0.78
43 INT16506 Positive_regulation of Binding of LPA and Crp 1 0.00 0.78 0.78
44 INT16498 Binding of ADRA1D and LPA 1 0.10 0.78 0.78
45 INT16497 Positive_regulation of Binding of ADRA1D and LPA 1 0.10 0.78 0.78
46 INT201941 IFNA1 Positive_regulation of Gene_expression of CXCL10 1 0.14 1.09 0.74
47 INT275554 Binding of CXCL10 and Cxcr3 1 0.03 2.18 0.71
48 INT67887 SCN5A Negative_regulation of INA 1 0.02 0.13 0.71
49 INT148452 Inhbe Regulation of Acvrl1 1 0.01 0.69 0.69
50 INT351367 LPA Regulation of Trpv1 1 0.01 0.83 0.69
51 INT178334 Binding of Pon1 and Chdh 1 0.11 11.45 0.66
52 INT62059 Positive_regulation of SCN5A Positive_regulation of Gene_expression of FOS 1 0.01 0.42 0.66
53 INT254352 Binding of CXCR4 and Positive_regulation of Gene_expression of CXCL12 1 0.14 1.8 0.66
54 INT160119 EPO Regulation of Gene_expression of NFKB1 1 0.02 0.2 0.64
55 INT63655 Binding of NPY and TAC1 1 0.39 0.17 0.64
56 INT167795 Negative_regulation of LPA Negative_regulation of Mag 1 0.01 0.84 0.64
57 INT167794 LPA Negative_regulation of Mag 1 0.01 0.77 0.63
58 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
59 INT113338 Binding of EPO and KNCN 1 0.02 1.39 0.62
60 INT159839 Binding of HTR1A and HTR7 1 0.39 0.38 0.62
61 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6
62 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
63 INT120206 Binding of UTS2R and Il1 1 0.17 1.28 0.59
64 INT120207 Binding of UTS2R and Il1f5 1 0.09 1.28 0.59
65 INT184100 Il6 Positive_regulation of Stat1 1 0.16 0.68 0.58
66 INT333477 CXCL10 Positive_regulation of TH1L 1 0.14 0.32 0.56
67 INT139429 LPA Positive_regulation of Negative_regulation of MBP 1 0.00 0.78 0.56
68 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55
69 INT201944 CXCL10 Positive_regulation of Phosphorylation of AKT1 1 0.09 0.79 0.55
70 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
71 INT351365 LPA Positive_regulation of Localization of Il6 1 0.00 1.79 0.54
72 INT125086 LPA Positive_regulation of Rtn4 1 0.00 0.36 0.54
73 INT113627 Binding of NPY and RHD 1 0.04 0 0.54
74 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
75 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
76 INT201939 CXCL10 Positive_regulation of MAPK1 1 0.11 0.72 0.52
77 INT346146 ADM Positive_regulation of Gene_expression of PERP 1 0.02 1.54 0.51
78 INT167583 ENPP2 Positive_regulation of Gene_expression of LPA 1 0.08 0.93 0.51
79 INT121821 Binding of STAT1 and Olr1583 1 0.00 0.21 0.51
80 INT176010 Binding of MTHFR and ZNF677 1 0.00 0.7 0.5
81 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
82 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49
83 INT138927 Ifng Positive_regulation of Gene_expression of Stat1 1 0.29 0.7 0.49
84 INT111244 Binding of BRS3 and SCN5A 1 0.00 0.72 0.48
85 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48
86 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48
87 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48
88 INT94018 Binding of EDN2 and EDN3 1 0.19 0 0.48
89 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47
90 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47
91 INT173293 LPA Positive_regulation of OR1S1 1 0.03 0.15 0.47
92 INT141964 Binding of ADM and RAMP1 1 0.30 2.63 0.47
93 INT176469 Binding of CXCL10 and CXCL9 1 0.01 0.84 0.46
94 INT252425 Positive_regulation of AR Positive_regulation of Gene_expression of CXCL10 1 0.00 0.9 0.44
95 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43
96 INT311590 EGF Regulation of Gene_expression of CXCL10 1 0.23 0.51 0.43
97 INT311591 CXCL10 Regulation of Gene_expression of EGF 1 0.23 0.51 0.43
98 INT54135 Binding of F13A1 and LPA 2 0.00 0.71 0.42
99 INT54136 Negative_regulation of Binding of F13A1 and LPA 1 0.00 0.42 0.42
100 INT201943 Regulation of Binding of DPP4 and CXCL10 1 0.20 0.58 0.42
101 INT326514 Sugt1 Negative_regulation of MTHFR 1 0.01 0.77 0.42
102 INT60456 SCN5A Regulation of Scn2a1 1 0.00 0 0.41
103 INT346151 Binding of ADM and GPER 1 0.01 0.99 0.41
104 INT251015 OLR1 Regulation of Protein_catabolism of MMP3 1 0.03 0.91 0.4
105 INT187145 Positive_regulation of Binding of CXCR3 and CXCL10 1 0.33 0.56 0.4
106 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
107 INT346150 Binding of ADM and FN1 1 0.10 0.93 0.39
108 INT346140 Positive_regulation of Binding of ADM and MMRN1 1 0.04 0.93 0.39
109 INT346139 Binding of ADM and MMRN1 1 0.03 0.93 0.39
110 INT346135 Positive_regulation of Binding of ADM and FN1 1 0.13 0.93 0.39
111 INT201948 Binding of DPP4 and CXCL10 1 0.27 0.54 0.39
112 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
113 INT332701 Binding of BDKRB1 and BDKRB2 1 0.01 0.5 0.39
114 INT346145 Binding of ADM and TPX2 1 0.01 1.05 0.35
115 INT275557 Negative_regulation of Binding of CXCL10 and Cxcr3 1 0.04 1.09 0.35
116 INT171266 TNF Positive_regulation of Gene_expression of CXCL10 1 0.11 0.48 0.35
117 INT136008 Binding of BDKRB2 and INSRR 1 0.01 0.17 0.34
118 INT315400 IFNA1 Positive_regulation of Phosphorylation of Stat1 1 0.02 0.4 0.33
119 INT190290 Binding of CXCL12 and VIPR1 1 0.06 0 0.33
120 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
121 INT184110 Jak1 Positive_regulation of Stat1 1 0.32 0.3 0.33
122 INT298472 LPA Positive_regulation of Gene_expression of CXCL16 1 0.05 0.41 0.32
123 INT337327 KNG1 Positive_regulation of BDKRB2 1 0.21 0.4 0.32
124 INT171293 TNF Positive_regulation of CXCL10 2 0.09 0.97 0.31
125 INT195664 APC Negative_regulation of F5 1 0.08 1.51 0.31
126 INT207434 LPA Regulation of Gene_expression of PLA2G7 1 0.11 0.73 0.31
127 INT101219 TNF Negative_regulation of Gene_expression of EPO 1 0.47 2.8 0.3
128 INT315392 IFNA1 Positive_regulation of Stat1 1 0.02 0.4 0.3
129 INT101220 TNF Negative_regulation of EPO 1 0.48 2.8 0.3
130 INT303983 Lep Positive_regulation of CXCL10 1 0.06 0.31 0.29
131 INT247083 Binding of F5 and PLAT 1 0.03 0.88 0.29
132 INT60448 NPY Positive_regulation of Gnrhr 1 0.01 0 0.29
133 INT187147 Positive_regulation of Binding of CXCL10 and GOPC 1 0.08 0.53 0.28
134 INT187144 Positive_regulation of Binding of CXCL10 and SLEB1 1 0.02 0.53 0.28
135 INT187146 Binding of CXCL10 and SLEB1 1 0.02 0.53 0.28
136 INT247081 Binding of F5 and F7 1 0.00 0.87 0.28
137 INT171722 IL4 Positive_regulation of Positive_regulation of CXCL10 1 0.04 0.67 0.28
138 INT187143 Binding of CXCL10 and GOPC 1 0.06 0.53 0.28
139 INT26577 SCN5A Positive_regulation of co 1 0.00 0 0.27
140 INT238632 Binding of EPB41 and Cask 1 0.44 0.78 0.27
141 INT72820 EDN3 Positive_regulation of Avp 1 0.31 0.64 0.27
142 INT332246 Ros1 Positive_regulation of Stat1 1 0.02 0.46 0.27
143 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
144 INT167582 ENPP2 Regulation of Gene_expression of LPA 1 0.05 0.61 0.26
145 INT207441 Binding of LPA and PLA2G7 1 0.10 0.56 0.26
146 INT108904 Binding of NPY and Npffr2 1 0.36 0.08 0.26
147 INT242215 Binding of ANG and OLR1 1 0.02 1.63 0.25
148 INT207438 Binding of OLR1 and ERAL1 1 0.08 0.5 0.25
149 INT311900 Acvrl1 Negative_regulation of Insrr 1 0.00 0.86 0.25
150 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24
151 INT279959 Tnfrsf1b Negative_regulation of Ahr 1 0.10 0.98 0.24
152 INT85011 ADM Regulation of CALCRL 1 0.06 0 0.24
153 INT253563 Csnk2a2 Regulation of Phosphorylation of Stat1 1 0.16 0.58 0.24
154 INT163760 Ifng Positive_regulation of Phosphorylation of Stat1 1 0.12 0.08 0.23
155 INT346134 ADM Regulation of Gene_expression of MMRN1 1 0.04 1.29 0.23
156 INT138929 Ifng Positive_regulation of Stat1 1 0.29 0.28 0.23
157 INT173294 LPA Positive_regulation of EGF 1 0.01 0.07 0.23
158 INT311908 Acvrl1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
159 INT138926 Regulation of Ifng Positive_regulation of Stat1 1 0.17 0.28 0.23
160 INT179186 Fcer2a Regulation of Positive_regulation of Ahr 1 0.05 1.23 0.23
161 INT346143 ADM Regulation of Gene_expression of TPX2 1 0.02 1.29 0.23
162 INT138931 Ifng Positive_regulation of Positive_regulation of Stat1 1 0.31 0.28 0.23
163 INT186351 Binding of Gast and Stat1 3 0.16 2.77 0.22
164 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22
165 INT355503 Positive_regulation of SCN10A Positive_regulation of Localization of NPY 1 0.17 1.32 0.22
166 INT339903 Binding of SCN5A and ZGLP1 1 0.01 0.18 0.22
167 INT94338 IFNG Positive_regulation of Phosphorylation of Stat1 1 0.01 0.26 0.21
168 INT94339 IFNG Positive_regulation of Localization of Stat1 1 0.01 0.26 0.21
169 INT141623 OLR1 Positive_regulation of Gene_expression of TF 1 0.01 1.39 0.21
170 INT171287 TNFSF12 Positive_regulation of CXCL10 1 0.01 0.8 0.21
171 INT339901 Binding of INS and SCN5A 1 0.01 0.18 0.2
172 INT12694 SMS Regulation of Localization of EPO 1 0.06 0 0.19
173 INT210551 Binding of KCNH2 and KCNE2 1 0.08 0 0.19
174 INT188921 Binding of Pc and Ahr 1 0.12 0 0.19
175 INT139015 STAT1 Negative_regulation of Gene_expression of PTGS2 1 0.01 0.36 0.19
176 INT332251 Il13 Positive_regulation of Stat1 1 0.14 1.4 0.18
177 INT188920 Pc Positive_regulation of Ahr 1 0.14 0 0.18
178 INT326464 KNG1 Positive_regulation of SERPING1 1 0.19 1.53 0.18
179 INT196303 Binding of SCN5A and ACCS 1 0.00 1.43 0.18
180 INT140095 Stat1 Positive_regulation of Positive_regulation of Ifng 1 0.52 0.42 0.18
181 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17
182 INT172254 Binding of ADM and TAS2R14 1 0.02 0 0.17
183 INT314078 Peo1 Negative_regulation of Stat1 1 0.31 1.23 0.17
184 INT12692 C1QL1 Positive_regulation of Localization of EPO 1 0.15 0 0.17
185 INT12693 SST Negative_regulation of Localization of EPO 1 0.08 0 0.17
186 INT269333 Binding of BDKRB2 and NOS3 1 0.02 0 0.17
187 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16
188 INT94017 Binding of EDN3 and INSRR 1 0.03 0 0.16
189 INT295433 Binding of PLOD1 and SCN5A 1 0.07 0.25 0.16
190 INT94014 Positive_regulation of Binding of EDN1 and EDN3 1 0.36 0 0.16
191 INT94023 Positive_regulation of Binding of EDN2 and EDN3 1 0.25 0 0.16
192 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
193 INT94019 Positive_regulation of Binding of EDN3 and INSRR 1 0.04 0 0.16
194 INT134202 Ahr Regulation of AHR 1 0.18 0.13 0.16
195 INT343848 Positive_regulation of TLR4 Positive_regulation of STAT1 1 0.17 0.16 0.15
196 INT298475 LPA Positive_regulation of Gene_expression of IL8 1 0.07 0.38 0.15
197 INT341815 Binding of ADORA2A and Aia1 1 0.00 1.29 0.15
198 INT206212 UTS2R Positive_regulation of CD24 1 0.09 0.71 0.15
199 INT221030 ELANE Positive_regulation of CXCL10 1 0.01 0.24 0.15
200 INT295273 STAT1 Regulation of Transcription of Hp 1 0.00 0.63 0.15

Single Events

The table below shows the top 100 pain related interactions that have been reported for blood circulation. They are ordered first by their pain relevance and then by number of times they were reported in blood circulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74
2 INT9650 Gene_expression of LPA 141 0.75 104.57 29
3 INT15458 Gene_expression of NPY 50 0.76 22.67 23.03
4 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23
5 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73
6 INT6848 Gene_expression of BDKRB2 40 0.75 17.19 20.04
7 INT11243 Localization of NPY 33 0.78 11.18 19.24
8 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88
9 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89
10 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79
11 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75
12 INT92237 Positive_regulation of Gene_expression of CXCL10 43 0.70 43.67 13.65
13 INT120828 Localization of CXCL10 29 0.68 18.01 12.17
14 INT66718 Positive_regulation of BDKRB2 21 0.64 9.89 11.6
15 INT15238 Positive_regulation of NPY 24 0.67 11.86 11.26
16 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03
17 INT93129 Negative_regulation of KCNH2 42 0.54 9.63 10.85
18 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
19 INT39301 Gene_expression of Chd7 50 0.26 27.06 8.13
20 INT7588 Regulation of NPY 13 0.44 6.97 7.97
21 INT11568 Gene_expression of ADORA2A 14 0.73 1.51 7.79
22 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
23 INT39406 Positive_regulation of OLR1 45 0.70 37.8 7.72
24 INT153814 Localization of LPA 19 0.65 18.25 7.68
25 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
26 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3
27 INT138922 Positive_regulation of Stat1 57 0.69 28.35 7.2
28 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17
29 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84
30 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67
31 INT138833 Binding of MTHFR 12 0.46 16.08 6.4
32 INT86600 Gene_expression of KCNH2 37 0.78 14.88 6.14
33 INT163756 Phosphorylation of Stat1 45 0.82 14.51 6.11
34 INT138915 Gene_expression of Stat1 144 0.77 69.53 5.85
35 INT118870 Positive_regulation of STAT1 36 0.67 26.18 5.46
36 INT83095 Regulation of Gene_expression of BDKRB2 2 0.59 4.06 5.39
37 INT23598 Binding of SCN5A 32 0.40 16 5.35
38 INT30209 Localization of SCN5A 24 0.72 7.95 5.35
39 INT92234 Regulation of CXCL10 15 0.42 8.37 5.09
40 INT48277 Regulation of BDKRB2 9 0.59 2.69 5.05
41 INT92236 Regulation of Gene_expression of CXCL10 6 0.42 7.12 4.92
42 INT11030 Binding of LPA 70 0.48 40.35 4.81
43 INT144481 Gene_expression of SERPING1 55 0.77 50.4 4.75
44 INT58622 Gene_expression of HTR7 13 0.75 2.86 4.7
45 INT14714 Negative_regulation of NPY 10 0.58 4.41 4.52
46 INT37912 Negative_regulation of Chd7 10 0.26 5.84 4.46
47 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
48 INT127667 Positive_regulation of Localization of CXCL10 5 0.59 5.89 4.09
49 INT73796 Localization of HTR7 8 0.78 2.39 3.87
50 INT121661 Binding of CXCL12 25 0.37 11.27 3.82
51 INT148085 Binding of CXCL10 14 0.32 10.22 3.81
52 INT24366 Positive_regulation of Localization of NPY 4 0.50 4.01 3.79
53 INT130646 Regulation of CXCL12 14 0.47 7.67 3.48
54 INT67468 Regulation of SCN5A 27 0.44 4.4 3.47
55 INT94337 Transcription of CXCL10 11 0.49 6.66 3.46
56 INT53347 Localization of BDKRB2 5 0.75 4.96 3.39
57 INT207449 Negative_regulation of OLR1 23 0.42 17.17 3.37
58 INT43985 Regulation of LPA 29 0.62 20.79 3.29
59 INT24296 Binding of NPY 6 0.48 2.03 3.23
60 INT184060 Negative_regulation of Stat1 28 0.58 17.44 3.19
61 INT38276 Negative_regulation of CXCL10 10 0.42 9.26 3.19
62 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
63 INT53065 Negative_regulation of Gene_expression of EPO 15 0.49 16.39 3.12
64 INT136266 Gene_expression of KCNQ1 23 0.64 8.34 3.11
65 INT109448 Negative_regulation of MTHFR 8 0.58 7.62 3.11
66 INT66720 Negative_regulation of BDKRB2 5 0.57 1.92 3.11
67 INT62652 Binding of HTR7 9 0.47 2.79 3.06
68 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
69 INT53348 Binding of BDKRB2 7 0.37 2.85 3
70 INT45503 Binding of EPO 42 0.48 24.85 2.88
71 INT94437 Positive_regulation of Gene_expression of OLR1 17 0.70 16.04 2.8
72 INT94327 Phosphorylation of Stat1 9 0.80 2.06 2.8
73 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
74 INT8112 Regulation of EPO 38 0.58 22.04 2.76
75 INT119839 Gene_expression of STAT1 17 0.75 8.36 2.7
76 INT124063 Gene_expression of MTHFR 9 0.65 6.22 2.67
77 INT13904 Transcription of NPY 6 0.67 1.57 2.66
78 INT123795 Positive_regulation of KCNQ1 13 0.49 3.53 2.65
79 INT100743 Regulation of KCNH2 6 0.54 2.37 2.61
80 INT43483 Gene_expression of DLL4 7 0.60 0.89 2.59
81 INT86602 Binding of KCNH2 14 0.36 4.65 2.58
82 INT77213 Transcription of ADORA2A 1 0.69 0 2.55
83 INT8111 Localization of EPO 32 0.81 19.53 2.54
84 INT101363 Regulation of OLR1 16 0.39 9.27 2.54
85 INT156130 Binding of SERPING1 29 0.42 26.16 2.52
86 INT39407 Binding of OLR1 18 0.48 14.79 2.51
87 INT77852 Binding of Chd7 8 0.31 4.1 2.51
88 INT121659 Positive_regulation of CXCL12 8 0.53 9.17 2.36
89 INT108482 Positive_regulation of Gene_expression of CXCL12 7 0.53 9.72 2.36
90 INT75756 Phosphorylation of LPA 5 0.68 0.67 2.35
91 INT250727 Negative_regulation of ADM 3 0.38 8.32 2.26
92 INT70962 Positive_regulation of SERPING1 33 0.69 27.32 2.14
93 INT306869 Gene_expression of E2F4 1 0.58 1.1 2.11
94 INT71487 Positive_regulation of HTR7 3 0.67 0.73 2.06
95 INT63627 Transcription of HTR7 5 0.67 0.79 2.03
96 INT141968 Positive_regulation of ADM 12 0.65 11.19 2
97 INT11905 Protein_catabolism of EPO 6 1.00 2.36 2
98 INT64682 Positive_regulation of Gene_expression of NPY 4 0.49 3.19 1.96
99 INT80798 Positive_regulation of Chd7 16 0.14 7.95 1.95
100 INT142461 Positive_regulation of Positive_regulation of Stat1 7 0.54 5.06 1.94
101 INT127250 Positive_regulation of Positive_regulation of SCN5A 3 0.38 1.71 1.86
102 INT15742 Negative_regulation of EPO 37 0.59 17.44 1.84
103 INT51584 Regulation of KCNQ1 10 0.44 3.21 1.84
104 INT100742 Regulation of Gene_expression of KCNH2 1 0.62 0.57 1.83
105 INT57063 Negative_regulation of HTR7 6 0.57 1.21 1.76
106 INT102449 Binding of ADM 12 0.33 5.85 1.73
107 INT119837 Positive_regulation of Gene_expression of STAT1 6 0.49 3.66 1.73
108 INT9648 Positive_regulation of Gene_expression of LPA 15 0.59 11.31 1.72
109 INT138917 Positive_regulation of Gene_expression of Stat1 63 0.69 36.76 1.71
110 INT14167 Negative_regulation of Positive_regulation of Ahr 5 0.51 1.54 1.71
111 INT113110 Negative_regulation of CXCL12 8 0.43 6.01 1.63
112 INT306853 Binding of E2F4 1 0.28 1.37 1.63
113 INT186309 Binding of Stat1 18 0.48 5.31 1.58
114 INT140089 Positive_regulation of Stat1 5 0.68 3.42 1.58
115 INT87571 Negative_regulation of KCNQ1 6 0.41 1.69 1.51
116 INT186064 Phosphorylation of STAT1 19 0.59 7.14 1.48
117 INT27762 Positive_regulation of Gene_expression of EPO 18 0.70 17.67 1.45
118 INT90604 Positive_regulation of Positive_regulation of Ahr 8 0.45 3.52 1.45
119 INT54805 Regulation of Ahr 7 0.22 4.14 1.41
120 INT139326 Gene_expression of Stat1 6 0.76 2.49 1.41
121 INT121820 Binding of STAT1 9 0.46 2.54 1.4
122 INT310167 Gene_expression of Acvrl1 2 0.40 5.47 1.4
123 INT130647 Regulation of Gene_expression of CXCL12 6 0.39 5.01 1.38
124 INT52589 Positive_regulation of Gene_expression of SCN5A 14 0.49 3.84 1.33
125 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31
126 INT216512 Gene_expression of C3AR1 13 0.70 8.44 1.31
127 INT252389 Negative_regulation of Gene_expression of ADM 2 0.38 4.78 1.3
128 INT245089 Localization of CXCL12 8 0.65 10.17 1.28
129 INT120406 Positive_regulation of Positive_regulation of BDKRB2 2 0.27 1.48 1.28
130 INT24609 Regulation of Localization of NPY 2 0.26 0.36 1.26
131 INT156672 Localization of SERPING1 10 0.74 12.15 1.25
132 INT29693 Binding of Ahr 11 0.31 13.27 1.23
133 INT118606 Protein_catabolism of CXCL10 2 0.86 0.98 1.22
134 INT141969 Positive_regulation of Gene_expression of ADM 4 0.57 4.07 1.2
135 INT51880 Regulation of Gene_expression of NPY 2 0.26 2.01 1.19
136 INT121814 Regulation of STAT1 3 0.43 0.83 1.15
137 INT119124 Positive_regulation of ADORA2A 4 0.35 0.96 1.14
138 INT178262 Transcription of Stat1 4 0.59 4.73 1.12
139 INT216849 Binding of ADORA2A 2 0.05 0 1.11
140 INT139325 Positive_regulation of Gene_expression of Stat1 3 0.68 1.18 1.1
141 INT201954 Positive_regulation of Protein_catabolism of CXCL10 1 0.41 0.7 1.1
142 INT163755 Positive_regulation of Phosphorylation of Stat1 4 0.60 1.87 1.09
143 INT139324 Positive_regulation of Phosphorylation of Stat1 3 0.44 1 1.09
144 INT17544 Negative_regulation of Gene_expression of NPY 3 0.42 1.97 1.05
145 INT217341 Negative_regulation of Gene_expression of CXCL10 6 0.25 4.97 1.04
146 INT61643 Gene_expression of ACVRL1 9 0.51 9.04 1.03
147 INT206140 Negative_regulation of Gene_expression of LPA 5 0.43 3.71 1.03
148 INT187158 Positive_regulation of Positive_regulation of CXCL10 2 0.38 1.6 1.03
149 INT119125 Regulation of ADORA2A 2 0.31 0 1.01
150 INT98171 Binding of DLL4 2 0.23 0.1 1.01
151 INT45079 Binding of Ahr 21 0.44 10.07 1
152 INT123536 Positive_regulation of MTHFR 7 0.57 4.74 1
153 INT37914 Regulation of Negative_regulation of Chd7 1 0.12 0 1
154 INT139019 Negative_regulation of STAT1 10 0.57 5.04 0.97
155 INT210571 Gene_expression of KCNE2 7 0.61 2.7 0.97
156 INT53066 Positive_regulation of Positive_regulation of EPO 4 0.49 2.38 0.95
157 INT57058 Regulation of HTR7 2 0.05 0.95 0.95
158 INT225094 Localization of ADM 5 0.63 3.89 0.91
159 INT77215 Localization of ADORA2A 2 0.77 0 0.91
160 INT128424 Transcription of STAT1 5 0.37 3.28 0.9
161 INT144482 Negative_regulation of Gene_expression of SERPING1 8 0.43 6.06 0.89
162 INT199483 Transcription of Stat1 2 0.43 1.14 0.89
163 INT163758 Regulation of Stat1 17 0.54 5.23 0.87
164 INT61642 Binding of ACVRL1 5 0.31 7.03 0.87
165 INT306888 Positive_regulation of Binding of E2F4 1 0.37 0.58 0.87
166 INT58758 Positive_regulation of Binding of NPY 1 0.30 0.57 0.85
167 INT137788 Negative_regulation of Positive_regulation of KCNQ1 1 0.21 1.02 0.83
168 INT191528 Positive_regulation of Localization of LPA 1 0.05 3.59 0.83
169 INT306840 Positive_regulation of Gene_expression of E2F4 1 0.37 0.58 0.82
170 INT162803 Regulation of F5 3 0.44 3.68 0.81
171 INT311884 Negative_regulation of Acvrl1 1 0.30 2.16 0.81
172 INT24367 Negative_regulation of Localization of NPY 1 0.43 0.4 0.81
173 INT16482 Regulation of Positive_regulation of LPA 1 0.08 0.79 0.79
174 INT265328 Positive_regulation of Acvrl1 5 0.40 3.18 0.78
175 INT238903 Negative_regulation of Gene_expression of OLR1 4 0.41 3.18 0.77
176 INT196325 Positive_regulation of Gene_expression of Chd7 7 0.14 4.28 0.76
177 INT290271 Negative_regulation of Binding of BDKRB2 1 0.37 0.99 0.76
178 INT174553 Localization of Stat1 17 0.80 6.62 0.73
179 INT200438 Negative_regulation of Gene_expression of SCN5A 6 0.36 1.93 0.71
180 INT98172 Regulation of Binding of DLL4 1 0.14 0.1 0.71
181 INT128422 Positive_regulation of Positive_regulation of STAT1 5 0.35 4.24 0.67
182 INT216510 Binding of C3AR1 2 0.06 1.59 0.67
183 INT208367 Regulation of Localization of Ahr 1 0.30 1.6 0.67
184 INT208371 Localization of Ahr 2 0.50 1.9 0.66
185 INT52590 Transcription of SCN5A 4 0.55 0.91 0.65
186 INT291371 Positive_regulation of Localization of CXCL12 2 0.35 2.8 0.65
187 INT75755 Positive_regulation of Phosphorylation of LPA 1 0.02 0 0.65
188 INT178250 Positive_regulation of Transcription of Stat1 2 0.43 2.72 0.64
189 INT176013 Negative_regulation of Binding of MTHFR 2 0.42 1.18 0.63
190 INT153699 Regulation of MTHFR 2 0.45 1.54 0.63
191 INT114942 Negative_regulation of Positive_regulation of Ahr 5 0.55 2.65 0.62
192 INT38720 Protein_catabolism of C3AR1 2 0.17 0.18 0.62
193 INT306884 Negative_regulation of E2F4 1 0.44 0.61 0.62
194 INT278714 Regulation of Phosphorylation of STAT1 1 0.21 0.81 0.62
195 INT43984 Regulation of Gene_expression of LPA 7 0.49 6.3 0.61
196 INT32159 Positive_regulation of Positive_regulation of NPY 2 0.45 0.09 0.61
197 INT106020 Transcription of EPO 8 0.71 9.34 0.6
198 INT65977 Gene_expression of RCAN1 6 0.70 3.72 0.59
199 INT73795 Negative_regulation of Positive_regulation of HTR7 1 0.41 0.08 0.58
200 INT207446 Localization of OLR1 6 0.73 3.38 0.57
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