GO:0008022

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Name protein C-terminus binding
Categary Function
Go Slim No
Go Link GO:0008022
Unique Molecular Interactions 2175
Total Molecular Interactions 2936
Total Single Events 21515
Pain Genes Associated 176

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein C-terminus binding. They are ordered first by their pain relevance and then by number of times they were reported for protein C-terminus binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
2 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59
3 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
4 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
5 INT229497 Binding of Vim and Ndel1 1 0.33 3.5 2.81
6 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
7 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
8 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
9 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
10 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
11 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
12 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
13 INT221181 Binding of GOPC and Flna 1 0.03 0.06 2.08
14 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06
15 INT169346 Nxn Negative_regulation of Dynll1 1 0.06 1.22 1.87
16 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
17 INT115048 Kcnip3 Regulation of Gene_expression of Pdyn 2 0.27 0.71 1.78
18 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76
19 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
20 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71
21 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66
22 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
23 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
24 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56
25 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
26 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
27 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
28 INT211744 Binding of Gopc and Mors1 1 0.10 0.2 1.48
29 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
30 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43
31 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
32 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
33 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
34 INT229496 Binding of Ndel1 and Gopc 1 0.08 2.05 1.36
35 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
36 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
37 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34
38 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32
39 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
40 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27
41 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
42 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
43 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
44 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
45 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24
46 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
47 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
48 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
49 INT105918 Binding of FUT1 and SLC9A3R2 1 0.00 0.14 1.2
50 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2
51 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18
52 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18
53 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
54 INT336559 SLC6A3 Positive_regulation of GOPC 1 0.08 1 1.15
55 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13
56 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13
57 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
58 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
59 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
60 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
61 INT283934 Phax Negative_regulation of Positive_regulation of Mapk14 1 0.03 2.06 1.09
62 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07
63 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06
64 INT119887 Binding of Atf4 and Usf1 1 0.21 0.15 1.05
65 INT266742 GOPC Regulation of Positive_regulation of ACR 1 0.02 0.36 1.05
66 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
67 INT154846 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Trpv1 1 0.23 0.07 1.05
68 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
69 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03
70 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
71 INT144661 Dnm1 Negative_regulation of Binding of Hbegf 1 0.24 0 1.01
72 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
73 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
74 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99
75 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99
76 INT238091 Binding of GRIP1 and Mmp24 1 0.00 0 0.98
77 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
78 INT89828 Atp4b Positive_regulation of Localization of Grip2 1 0.10 0.54 0.97
79 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
80 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95
81 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
82 INT166790 HRAS Negative_regulation of Gene_expression of PTGER1 1 0.01 1.46 0.95
83 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 0.21 0.98 0.95
84 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94
85 INT296283 Kcnip3 Regulation of Positive_regulation of Cysltr1 1 0.01 0.85 0.94
86 INT252877 Prkaca Positive_regulation of Regulation of Grip2 1 0.01 0.22 0.94
87 INT264924 Binding of Pag1 and Gopc 1 0.06 0.19 0.94
88 INT252878 Prkaca Regulation of Regulation of Grip2 1 0.01 0.22 0.94
89 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93
90 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
91 INT318461 Nnat Positive_regulation of Mapk14 1 0.05 0.97 0.92
92 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
93 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
94 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
95 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 0.03 1.09 0.92
96 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.09 0.91
97 INT306823 Binding of E2F4 and GOPC 1 0.06 0.23 0.91
98 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
99 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9
100 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 0.06 0.2 0.9
101 INT121701 HRAS Negative_regulation of MMP1 1 0.06 0.2 0.89
102 INT121704 HRAS Negative_regulation of MMP3 1 0.06 0.19 0.89
103 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88
104 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 0.06 0.19 0.88
105 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
106 INT314207 Ngf Negative_regulation of Phosphorylation of Mapk14 1 0.33 0.4 0.88
107 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
108 INT305406 Binding of CAV3 and ST8SIA2 1 0.16 0 0.86
109 INT285660 Cnrip1 Negative_regulation of Kcnk3 1 0.00 0.23 0.85
110 INT285656 Cnrip1 Negative_regulation of Kcnk3 1 0.00 0.23 0.85
111 INT120820 Binding of ASIC3 and Dlg4 3 0.02 0.11 0.84
112 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
113 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
114 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
115 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
116 INT108072 Grip2 Positive_regulation of Gene_expression of Fos 1 0.08 0.21 0.82
117 INT155761 Binding of Nos1 and Tjp1 1 0.13 1.01 0.82
118 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
119 INT288201 Mapk14 Positive_regulation of Cish 1 0.03 0.06 0.82
120 INT269455 Binding of RAB5A and GOPC 1 0.08 0 0.82
121 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
122 INT128590 Mapk14 Regulation of Nav1 1 0.21 0.25 0.82
123 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
124 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
125 INT155760 Binding of Nos1 and Dlg4 1 0.13 1.01 0.82
126 INT214370 Slc6a3 Regulation of Amph 1 0.14 0.44 0.82
127 INT293011 GPM6A Regulation of GOPC 1 0.00 0 0.81
128 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8
129 INT328982 Binding of Igfals and Cts 1 0.05 0.92 0.8
130 INT168648 Positive_regulation of Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.35 1.51 0.8
131 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79
132 INT168647 Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.52 1.51 0.79
133 INT347391 Positive_regulation of RYBP Positive_regulation of Sdcbp 1 0.00 0.22 0.79
134 INT347398 RYBP Positive_regulation of Positive_regulation of Sdcbp 1 0.00 0.22 0.79
135 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
136 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
137 INT152857 PRS Regulation of Nefl 1 0.00 0.19 0.77
138 INT152833 Nefl Regulation of Prkcg 1 0.12 0.19 0.77
139 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77
140 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
141 INT296786 Gopc Regulation of Positive_regulation of Il1 1 0.02 1.37 0.77
142 INT296798 Gopc Regulation of Positive_regulation of TNF 1 0.01 1.37 0.77
143 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
144 INT152834 Nefl Regulation of Nefh 1 0.10 0.19 0.77
145 INT152947 Dlg4 Regulation of Sgk1 1 0.09 0.18 0.76
146 INT152945 Dlg4 Regulation of Cap1 1 0.11 0.18 0.76
147 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
148 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
149 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
150 INT117412 RYBP Negative_regulation of LIG4 1 0.00 0.42 0.76
151 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75
152 INT152944 Dlg4 Regulation of Gpr88 1 0.12 0.18 0.75
153 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
154 INT328978 Binding of Igfals and Muted 1 0.02 0.85 0.73
155 INT328980 Binding of Cst7 and Igfals 1 0.06 0.85 0.73
156 INT269454 Positive_regulation of Binding of GOPC and HHIP 1 0.01 0 0.73
157 INT328975 Binding of Igfals and Mup1 1 0.11 0.85 0.73
158 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72
159 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
160 INT296289 Grin2a Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
161 INT148453 Gene_expression of Inhbe Positive_regulation of Src 1 0.06 0.68 0.72
162 INT220746 EGF Positive_regulation of Gene_expression of GOPC 1 0.13 0 0.72
163 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
164 INT262580 Ngf Positive_regulation of Hspg2 1 0.03 0.35 0.72
165 INT317573 Binding of Oprm1 and Pik3r1 1 0.12 0.33 0.71
166 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 0.00 0 0.7
167 INT207542 Sp1 Regulation of Oprm1 1 0.15 0.06 0.7
168 INT98958 Binding of NR5A2 and SP1 1 0.00 0 0.7
169 INT282139 Grm1 Regulation of Grip2 1 0.00 0.62 0.69
170 INT282141 Grm5 Regulation of Grip2 1 0.00 0.61 0.69
171 INT110650 Pla2g3 Regulation of Grip2 1 0.01 0 0.68
172 INT232613 Gopc Regulation of Cysltr1 1 0.02 0.58 0.68
173 INT164783 Positive_regulation of Mapk14 Regulation of Gene_expression of Cx3cr1 1 0.19 0.81 0.68
174 INT250871 Il1a Positive_regulation of Protein_catabolism of Ecm1 1 0.01 1.44 0.68
175 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
176 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67
177 INT240065 KCNIP3 Regulation of Transcription of PDYN 1 0.42 0.88 0.67
178 INT207547 Sp1 Regulation of Qsox1 1 0.05 0.06 0.67
179 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
180 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
181 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
182 INT191332 AMPH Positive_regulation of Mapk1 1 0.76 0 0.66
183 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
184 INT191330 AMPH Positive_regulation of Vta1 1 0.07 0 0.66
185 INT191331 AMPH Positive_regulation of Gene_expression of Vta1 1 0.07 0 0.66
186 INT166299 Binding of Mapk14 and Gpbar1 1 0.13 0.64 0.65
187 INT166302 Negative_regulation of Binding of Mapk14 and Gpbar1 1 0.12 0.64 0.65
188 INT27526 Binding of Sdcbp and Eda 1 0.13 0 0.65
189 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 0.00 1.12 0.65
190 INT168205 Binding of Dlg4 and Pik3cd 1 0.11 0.37 0.65
191 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65
192 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
193 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64
194 INT309664 Binding of Pik3r1 and Cia1 1 0.02 1.32 0.64
195 INT288202 Negative_regulation of Cd14 Positive_regulation of Positive_regulation of Mapk14 1 0.09 1.08 0.64
196 INT264946 Binding of FPR1 and GOPC 1 0.08 0.21 0.64
197 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64
198 INT264952 Binding of GOPC and BOC 1 0.05 0.22 0.64
199 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
200 INT223155 Binding of Mapk14 and Stat4 1 0.36 0.84 0.63

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein C-terminus binding. They are ordered first by their pain relevance and then by number of times they were reported in protein C-terminus binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
2 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55
3 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6
4 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
5 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
6 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
7 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
8 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67
9 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
10 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
11 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75
12 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4
13 INT173693 Localization of Gopc 249 0.65 70.49 38.81
14 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
15 INT49110 Regulation of Grip2 46 0.61 13.57 30.87
16 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08
17 INT7664 Negative_regulation of Grip2 68 0.49 10.11 29.93
18 INT15610 Localization of GOPC 223 0.65 68.26 28.7
19 INT56524 Gene_expression of Grip2 67 0.74 14.77 26.23
20 INT48832 Positive_regulation of Grip2 48 0.69 12.13 25.99
21 INT172458 Regulation of Gopc 155 0.53 62.57 24.86
22 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71
23 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16
24 INT35711 Positive_regulation of Sdcbp 110 0.60 50.45 22.11
25 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
26 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
27 INT170444 Binding of Gopc 172 0.39 45.05 20.71
28 INT105021 Binding of GOPC 187 0.40 60.39 20.38
29 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98
30 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68
31 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93
32 INT48690 Localization of Grip2 33 0.61 6.13 16.81
33 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
34 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
35 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65
36 INT49263 Binding of Grip2 31 0.41 9.86 16.38
37 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33
38 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29
39 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
40 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
41 INT171666 Regulation of GOPC 117 0.39 40.41 15.47
42 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41
43 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15
44 INT41558 Localization of Sp1 9 0.48 0.56 14.9
45 INT97100 Negative_regulation of Dlg4 16 0.58 6.18 14.36
46 INT35120 Gene_expression of Sdcbp 68 0.67 21.33 13.96
47 INT104954 Negative_regulation of Positive_regulation of Mapk14 29 0.58 17.71 13.31
48 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21
49 INT24082 Negative_regulation of Sp1 13 0.40 1.19 13.11
50 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
51 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
52 INT88789 Gene_expression of Dlg4 26 0.78 4.41 12.74
53 INT110025 Positive_regulation of Positive_regulation of Mapk14 39 0.63 20.67 12.71
54 INT96924 Positive_regulation of Hspg2 40 0.49 14.5 12.32
55 INT117113 Regulation of Mapk14 28 0.45 16.71 11.99
56 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68
57 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63
58 INT103923 Negative_regulation of Positive_regulation of Mapk14 23 0.53 13.95 10.64
59 INT238920 Positive_regulation of SLC9A3R2 44 0.50 27.86 10.51
60 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
61 INT178306 Negative_regulation of Gene_expression of Gopc 71 0.37 26.43 9.74
62 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
63 INT183000 Transcription of KCNIP3 4 0.62 12.89 9.59
64 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06
65 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
66 INT182995 Gene_expression of KCNIP3 19 0.69 13.28 8.81
67 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
68 INT108643 Gene_expression of Dlg4 61 0.76 8.63 8.58
69 INT168096 Transcription of Cav3 1 0.72 7.23 8.58
70 INT22481 Gene_expression of CADM1 28 0.65 30.26 8.5
71 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33
72 INT114171 Phosphorylation of Grip2 11 0.49 5.75 8.31
73 INT36798 Gene_expression of Mki67 178 0.77 132 8.24
74 INT112099 Negative_regulation of Dlg2 2 0.40 6.17 8.16
75 INT175526 Phosphorylation of Gopc 73 0.53 21.08 7.86
76 INT159750 Negative_regulation of Gene_expression of Mapk14 15 0.40 10.88 7.81
77 INT57176 Positive_regulation of Dynll1 9 0.49 4.76 7.71
78 INT182976 Negative_regulation of KCNIP3 2 0.51 8.49 7.67
79 INT200874 Positive_regulation of Localization of Gopc 27 0.38 5.69 7.5
80 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
81 INT74099 Negative_regulation of Dynll1 8 0.56 3.43 7.25
82 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16
83 INT128695 Regulation of Gene_expression of Mapk14 14 0.44 11.49 7.14
84 INT75382 Negative_regulation of HSPG2 20 0.57 15.18 7.03
85 INT97099 Positive_regulation of Dlg4 13 0.60 3.04 6.98
86 INT170381 Transcription of Gopc 59 0.60 15.96 6.82
87 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
88 INT35712 Regulation of Sdcbp 19 0.23 5.3 6.58
89 INT88786 Binding of Dlg4 11 0.46 2.73 6.58
90 INT48555 Binding of SP1 30 0.46 11.38 6.53
91 INT112101 Gene_expression of Dlg2 9 0.73 5.06 6.5
92 INT171691 Protein_catabolism of Ecm1 31 0.20 11.57 6.38
93 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
94 INT133971 Binding of Kcnip3 4 0.42 5.54 6.12
95 INT128587 Localization of Mapk14 15 0.81 8.41 6.1
96 INT37745 Positive_regulation of Gene_expression of Sdcbp 22 0.60 5.15 6.02
97 INT26585 Gene_expression of Vim 117 0.77 39.97 6
98 INT170296 Regulation of Gene_expression of Gopc 33 0.38 12.49 6
99 INT251134 Binding of Dlg2 6 0.31 4.26 5.99
100 INT41604 Negative_regulation of Localization of Sp1 2 0.30 0.32 5.86
101 INT87470 Gene_expression of SDC1 27 0.78 24.86 5.81
102 INT179810 Protein_catabolism of Ecm1 30 0.11 18.28 5.75
103 INT206950 Positive_regulation of Atf4 14 0.45 7.02 5.71
104 INT131944 Gene_expression of Mki67 30 0.53 6.58 5.63
105 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
106 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
107 INT100222 Binding of Src 9 0.26 5.41 5.37
108 INT125996 Gene_expression of Nsf 7 0.75 1.73 5.3
109 INT149217 Gene_expression of Kcnip3 2 0.63 6.31 5.26
110 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23
111 INT176524 Binding of Mapk14 19 0.43 12.54 5.21
112 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15
113 INT126047 Regulation of Phosphorylation of Mapk14 7 0.60 5.05 5.03
114 INT116744 Binding of Pik3r1 22 0.36 12.77 5.01
115 INT240092 Negative_regulation of Gene_expression of KCNIP3 1 0.51 5.58 4.96
116 INT112883 Gene_expression of Hspg2 22 0.65 6.54 4.95
117 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
118 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
119 INT17312 Binding of HSPG2 30 0.41 33.01 4.88
120 INT171472 Binding of Mapk14 10 0.36 6.79 4.83
121 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
122 INT178754 Positive_regulation of Localization of GOPC 32 0.43 10.1 4.73
123 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
124 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
125 INT105289 Gene_expression of Tjp1 28 0.76 11.72 4.67
126 INT88790 Negative_regulation of Gene_expression of Dlg4 6 0.59 1.53 4.66
127 INT116748 Positive_regulation of Gene_expression of Pik3r1 18 0.49 9.83 4.63
128 INT98453 Positive_regulation of Src 19 0.47 7.84 4.62
129 INT88909 Positive_regulation of Gene_expression of Dnm1 6 0.70 3.43 4.59
130 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54
131 INT115927 Negative_regulation of Hspg2 27 0.57 4.16 4.53
132 INT170604 Negative_regulation of Gene_expression of GOPC 50 0.35 12.71 4.51
133 INT74393 Gene_expression of Dynll1 8 0.65 2.64 4.39
134 INT145532 Localization of Dlg4 25 0.79 1.97 4.36
135 INT35122 Negative_regulation of Sdcbp 43 0.51 22.01 4.34
136 INT116747 Regulation of Pik3r1 18 0.60 9.33 4.34
137 INT196782 Positive_regulation of Ppp2ca 32 0.61 1.89 4.33
138 INT134968 Localization of Ecm1 20 0.32 27.27 4.31
139 INT107771 Localization of HSPG2 10 0.78 8.47 4.3
140 INT63113 Positive_regulation of HRAS 30 0.67 22.85 4.28
141 INT80626 Binding of KCNIP3 46 0.43 9.84 4.27
142 INT88182 Gene_expression of Atp2a2 40 0.78 22.91 4.26
143 INT20981 Binding of HRAS 42 0.48 24.49 4.23
144 INT110024 Negative_regulation of Gene_expression of Mapk14 19 0.42 7.83 4.21
145 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13
146 INT88787 Transcription of Dlg4 4 0.69 0.83 4.09
147 INT120810 Binding of Dlg4 38 0.41 3.55 4.03
148 INT73114 Gene_expression of Kcnk3 32 0.77 1.57 4.03
149 INT90277 Negative_regulation of Ppp2ca 15 0.41 4.04 4.02
150 INT61118 Gene_expression of Nefl 11 0.75 4.02 4.02
151 INT131782 Regulation of Positive_regulation of Mapk14 7 0.43 2.68 4.02
152 INT44789 Binding of Sdcbp 10 0.36 1.65 4.01
153 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
154 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97
155 INT100566 Transcription of Grip2 6 0.25 1.22 3.94
156 INT169475 Localization of HRAS 14 0.73 9.02 3.9
157 INT32553 Regulation of Pfkm 7 0.62 0.64 3.89
158 INT110021 Positive_regulation of Gene_expression of Mapk14 29 0.46 19.06 3.86
159 INT123411 Gene_expression of Sp1 15 0.69 4.2 3.79
160 INT174277 Positive_regulation of Positive_regulation of Gopc 23 0.33 8.08 3.73
161 INT170899 Negative_regulation of Positive_regulation of Gopc 16 0.19 5.46 3.71
162 INT88906 Gene_expression of Dnm1 5 0.78 10.48 3.7
163 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
164 INT92678 Positive_regulation of Ecm1 30 0.09 28.41 3.68
165 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
166 INT240080 Negative_regulation of Transcription of KCNIP3 1 0.51 4.34 3.61
167 INT122327 Regulation of Src 6 0.59 0.59 3.6
168 INT47678 Positive_regulation of Positive_regulation of HSPG2 7 0.49 3.94 3.56
169 INT175531 Positive_regulation of Phosphorylation of Gopc 11 0.33 2.53 3.54
170 INT49702 Negative_regulation of Negative_regulation of Grip2 9 0.43 1.77 3.54
171 INT132187 Gene_expression of Ecm1 14 0.21 8.12 3.52
172 INT102076 Regulation of DST 15 0.22 10 3.5
173 INT169344 Positive_regulation of Gene_expression of Dynll1 3 0.49 2.34 3.48
174 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38
175 INT69990 Negative_regulation of Nefl 11 0.59 2.82 3.38
176 INT171233 Binding of Ecm1 25 0.07 12.41 3.36
177 INT137350 Phosphorylation of Src 13 0.45 4.14 3.32
178 INT151421 Negative_regulation of Positive_regulation of Sdcbp 11 0.30 6.61 3.32
179 INT170606 Regulation of Gene_expression of GOPC 31 0.37 6.08 3.31
180 INT200872 Negative_regulation of Localization of Gopc 16 0.22 5.61 3.3
181 INT133086 Positive_regulation of Phosphorylation of Map2k7 1 0.05 4.34 3.27
182 INT196779 Phosphorylation of Ppp2ca 28 0.72 1.86 3.25
183 INT41559 Positive_regulation of Sp1 7 0.45 2.65 3.24
184 INT165911 Localization of Pik3r1 15 0.51 7.94 3.2
185 INT94925 Regulation of Gene_expression of Grip2 7 0.55 4.23 3.18
186 INT100591 Regulation of Kcnip3 3 0.50 2.51 3.17
187 INT144068 Binding of Nsf 9 0.48 7.67 3.16
188 INT154198 Binding of Pick1 9 0.48 6.91 3.16
189 INT123409 Binding of Sp1 20 0.39 3.18 3.15
190 INT11202 Positive_regulation of Pfkm 8 0.57 1.74 3.06
191 INT133082 Phosphorylation of Map2k7 5 0.15 4.27 3.05
192 INT109496 Gene_expression of KCNK3 9 0.78 0.59 3.02
193 INT180971 Protein_catabolism of GOPC 21 0.77 6.15 2.98
194 INT175524 Negative_regulation of Phosphorylation of Gopc 14 0.20 2.74 2.96
195 INT52256 Negative_regulation of Amph 3 0.38 0.42 2.94
196 INT3463 Gene_expression of Igfals 21 0.39 21.1 2.93
197 INT103607 Binding of Sp1 7 0.42 1.26 2.92
198 INT32675 Regulation of Amph 3 0.39 0.45 2.9
199 INT191125 Gene_expression of Igfals 12 0.25 12.96 2.89
200 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
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