GO:0008026

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Name ATP-dependent helicase activity
Categary Function
Go Slim No
Go Link GO:0008026
Unique Molecular Interactions 31
Total Molecular Interactions 48
Total Single Events 202
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ATP-dependent helicase activity. They are ordered first by their pain relevance and then by number of times they were reported for ATP-dependent helicase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140238 HELQ Regulation of MC1R 1 0.01 0.5 1.2
2 INT293704 Binding of TNF and DDX41 1 0.00 1.01 0.61
3 INT293703 Binding of DDX41 and C21orf91 1 0.00 0.99 0.42
4 INT330519 Binding of CD8A and DICER1 1 0.08 0.99 0.38
5 INT144189 Binding of S100A8 and DDX53 1 0.39 1.17 0.38
6 INT308701 Binding of AQP4 and DDX41 1 0.15 3.53 0.32
7 INT316713 Binding of Ddx41 and Pain1 1 0.00 0.94 0.28
8 INT308708 DDX41 Regulation of AQP4 1 0.10 2.79 0.26
9 INT143503 IFNG Positive_regulation of CETN1 1 0.00 0.35 0.16
10 INT143505 Aif1 Positive_regulation of CETN1 1 0.01 0.35 0.16
11 INT346451 Positive_regulation of Binding of IFNA1 and DDX58 1 0.01 0.54 0.15
12 INT346450 Binding of IFNA1 and DDX58 1 0.01 0.54 0.15
13 INT350711 Ifnb1 Negative_regulation of Gene_expression of DICER1 1 0.03 0.15 0.14
14 INT308709 Positive_regulation of Binding of AQP4 and DDX41 1 0.18 1.19 0.14
15 INT290314 MAVS Positive_regulation of DDX58 1 0.06 0.63 0.13
16 INT308704 Binding of DDX41 and M1 1 0.02 2.09 0.1
17 INT322560 Binding of TNFSF10 and DICER1 1 0.07 1.76 0.07
18 INT203419 Binding of EIF4A1 and Gtf3a 1 0.00 0.5 0.07
19 INT346453 Binding of DDX58 and IFIH1 1 0.00 1.04 0.03
20 INT128751 Binding of Ddx41 and Igis1 1 0.00 0 0
21 INT219256 Binding of Ddx41 and G2e3 1 0.01 1.63 0
22 INT341232 Binding of EIF4A2 and Eif4e 1 0.06 0 0
23 INT352392 Binding of ENOSF1 and Recql4 1 0.02 6.62 0
24 INT191183 Binding of GRB2 and RECQL5 1 0.37 0.17 0
25 INT301464 Binding of Smyd3 and Dhx8 1 0.05 0.08 0
26 INT301473 Binding of Dhx8 and Smyd2 1 0.06 0.14 0
27 INT191186 Binding of EGFR and RECQL5 1 0.35 0.34 0
28 INT272524 DICER1 Negative_regulation of Dmpk 1 0.04 0.07 0
29 INT248387 CHD5 Regulation of Gene_expression of TP53 1 0.20 0.83 0
30 INT286186 Binding of Blm and Fig4 1 0.09 0.34 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ATP-dependent helicase activity. They are ordered first by their pain relevance and then by number of times they were reported in ATP-dependent helicase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT78023 Gene_expression of DDX41 13 0.65 23.55 3.84
2 INT190280 Gene_expression of DICER1 12 0.65 9.54 2.67
3 INT129231 Gene_expression of Ddx41 29 0.63 9.73 1.52
4 INT188883 Binding of DDX41 9 0.39 11.55 1.29
5 INT330526 Positive_regulation of Gene_expression of DICER1 5 0.30 3.34 1.18
6 INT219247 Positive_regulation of Ddx41 9 0.36 6.7 0.84
7 INT157363 Gene_expression of DDX53 2 0.54 2.83 0.71
8 INT314566 Positive_regulation of Dhx8 1 0.17 0.07 0.67
9 INT128750 Binding of Ddx41 13 0.34 4.35 0.57
10 INT315712 Positive_regulation of Gene_expression of Ddx41 3 0.31 2.24 0.46
11 INT78022 Positive_regulation of Gene_expression of DDX41 1 0.45 1.26 0.44
12 INT346479 Positive_regulation of DDX58 1 0.06 5.3 0.42
13 INT272502 Transcription of DICER1 3 0.08 2.14 0.39
14 INT343811 Positive_regulation of Transcription of DICER1 1 0.06 2.06 0.39
15 INT144190 Binding of DDX53 1 0.36 1.17 0.38
16 INT343810 Binding of DICER1 1 0.05 1.88 0.35
17 INT330525 Positive_regulation of DICER1 2 0.17 1.34 0.34
18 INT100650 Gene_expression of Recql4 2 0.42 1.72 0.28
19 INT100646 Regulation of Recql4 1 0.05 0.1 0.28
20 INT100649 Regulation of Gene_expression of Recql4 1 0.05 0.1 0.28
21 INT78941 Positive_regulation of DDX41 4 0.45 2.46 0.23
22 INT350691 Localization of DICER1 1 0.08 1.18 0.23
23 INT308714 Regulation of Gene_expression of DDX41 1 0.08 1.9 0.19
24 INT315714 Phosphorylation of Ddx41 1 0.12 0.97 0.14
25 INT350685 Negative_regulation of Gene_expression of DICER1 1 0.05 0.15 0.14
26 INT350676 Regulation of Gene_expression of DICER1 1 0.07 0.16 0.14
27 INT308715 Regulation of DDX41 1 0.08 2.12 0.12
28 INT315713 Negative_regulation of Binding of Ddx41 1 0.06 1 0.1
29 INT188884 Localization of DDX41 3 0.60 2.56 0.09
30 INT286183 Regulation of Blm 1 0.36 1.3 0.09
31 INT286184 Gene_expression of Blm 1 0.39 2.16 0.09
32 INT78942 Negative_regulation of DDX41 1 0.57 1.79 0.08
33 INT82955 Localization of Ddx41 4 0.53 1.08 0.06
34 INT272508 Regulation of DICER1 4 0.11 1.21 0.05
35 INT290325 Binding of DDX58 1 0.04 0.52 0.05
36 INT194456 Gene_expression of CETN1 1 0.01 0 0.04
37 INT346490 Phosphorylation of DDX58 1 0.07 1.03 0.03
38 INT190271 Negative_regulation of DICER1 2 0.04 0.24 0
39 INT301435 Binding of Dhx8 1 0.06 0.06 0
40 INT248395 Regulation of CHD5 1 0.24 0.96 0
41 INT237994 Negative_regulation of Localization of Ddx41 1 0.04 0.08 0
42 INT303322 Positive_regulation of Phosphorylation of EIF4A2 1 0.08 0.16 0
43 INT248392 Positive_regulation of Gene_expression of CHD5 1 0.45 0.87 0
44 INT326426 Negative_regulation of Ddx41 1 0.04 0.32 0
45 INT248393 Binding of CHD5 1 0.33 0.22 0
46 INT248394 Gene_expression of CHD5 1 0.70 2.3 0
47 INT286182 Positive_regulation of Gene_expression of Blm 1 0.29 0.53 0
48 INT303318 Phosphorylation of EIF4A2 1 0.11 0.16 0
49 INT248397 Positive_regulation of CHD5 1 0.39 0.24 0
50 INT341209 Binding of EIF4A2 1 0.06 0 0
51 INT352844 Protein_catabolism of DICER1 1 0.12 0 0
52 INT191212 Gene_expression of RECQL5 1 0.63 0.17 0
53 INT248396 Negative_regulation of CHD5 1 0.39 0.93 0
54 INT221875 Binding of CETN1 1 0.02 0.19 0
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