GO:0008035

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Name high-density lipoprotein particle binding
Categary Function
Go Slim No
Go Link GO:0008035
Unique Molecular Interactions 130
Total Molecular Interactions 206
Total Single Events 1263
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for high-density lipoprotein particle binding. They are ordered first by their pain relevance and then by number of times they were reported for high-density lipoprotein particle binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
2 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
3 INT178334 Binding of Pon1 and Chdh 1 0.11 11.45 0.66
4 INT209854 IL4 Positive_regulation of Gene_expression of CD36 1 0.51 1.2 0.65
5 INT136749 COX5A Positive_regulation of Gene_expression of SCARB1 1 0.52 0.36 0.45
6 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
7 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43
8 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
9 INT209858 TNF Regulation of Transcription of CD36 1 0.27 0 0.4
10 INT56876 Regulation of Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
11 INT56875 Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
12 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37
13 INT209855 NFE2L2 Positive_regulation of Gene_expression of CD36 1 0.27 0.72 0.32
14 INT334024 Ccl25 Positive_regulation of Gene_expression of CD36 1 0.31 0.36 0.31
15 INT334023 pma Positive_regulation of Gene_expression of CD36 1 0.04 0.31 0.28
16 INT213029 Positive_regulation of Binding of Apoa1 and Scarb1 1 0.09 3.38 0.27
17 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
18 INT209849 TNF Positive_regulation of Gene_expression of CD36 1 0.69 0.18 0.25
19 INT186191 Binding of SCARB1 and TBP 1 0.03 2.57 0.24
20 INT198643 CD36 Positive_regulation of CADM1 1 0.01 1.07 0.24
21 INT305798 Binding of APOA1 and OxP-11D 1 0.02 0.45 0.23
22 INT209856 IL1A Negative_regulation of Transcription of CD36 1 0.26 0.1 0.22
23 INT209848 TNF Positive_regulation of CD36 1 0.46 0.24 0.22
24 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21
25 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21
26 INT209857 IL10 Negative_regulation of Gene_expression of CD36 1 0.31 0.16 0.2
27 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2
28 INT252330 Binding of Cd36 and Cd47 2 0.10 0.72 0.19
29 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18
30 INT232005 Binding of Cd36 and Tsp1 2 0.25 1.81 0.16
31 INT43510 Apoa2 Positive_regulation of Localization of POMC 1 0.03 0 0.16
32 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14
33 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12
34 INT33752 Apoa2 Regulation of Localization of POMC 1 0.06 0 0.12
35 INT33750 Apoa2 Regulation of Agt 1 0.07 0 0.12
36 INT33751 Apoa2 Positive_regulation of Positive_regulation of POMC 1 0.09 0 0.11
37 INT2458 Apoa2 Positive_regulation of Localization of Avp 1 0.10 0 0.11
38 INT213042 Apoa1 Positive_regulation of Nos3 1 0.10 2.17 0.11
39 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11
40 INT328370 Binding of CD36 and Fabp1 1 0.01 0.64 0.11
41 INT305780 Binding of APOA1 and LRCH2 1 0.00 0.19 0.1
42 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
43 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08
44 INT301613 Binding of Fabp4 and Cd36 1 0.05 0.38 0.08
45 INT301614 Binding of Slc27a1 and Cd36 1 0.09 0.38 0.08
46 INT43121 Apoa2 Regulation of Smc1b 1 0.02 0 0.08
47 INT190885 Binding of Apoa2 and Hdl1 1 0.02 0.73 0.07
48 INT279652 PPARA Positive_regulation of Gene_expression of Apoa1 1 0.00 0.75 0.07
49 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
50 INT186188 Binding of SCARB1 and PDZK1 1 0.53 0.54 0.05
51 INT334027 Ccl25 Regulation of Gene_expression of CD36 1 0.14 0.24 0.05
52 INT335047 PPARA Positive_regulation of Gene_expression of APOA1 1 0.20 0.42 0.05
53 INT239348 Binding of Apoa1 and Hdl1 1 0.03 3.34 0.05
54 INT296023 Positive_regulation of Apoa2 Negative_regulation of APOA1 1 0.50 0.35 0.05
55 INT296024 Apoa2 Negative_regulation of CETP 1 0.39 0.35 0.05
56 INT186185 Binding of SCARB1 and SCARB2 1 0.22 0.58 0.05
57 INT334026 pma Regulation of Gene_expression of CD36 1 0.02 0.16 0.05
58 INT43124 Apoa2 Positive_regulation of Positive_regulation of NA 1 0.07 0 0.05
59 INT296025 Apoa2 Negative_regulation of APOA1 1 0.47 0.35 0.05
60 INT236722 Ppara Positive_regulation of Binding of Apoa1 1 0.10 0.18 0.04
61 INT186187 LDLR Regulation of Gene_expression of SCARB1 1 0.17 1.71 0.04
62 INT178503 Binding of Cd36 and ecs 1 0.01 0.34 0.04
63 INT288908 Apoa1 Positive_regulation of Gene_expression of HSD11B1 1 0.03 0.53 0.04
64 INT325025 Apoa2 Positive_regulation of Hdl1 1 0.05 1.03 0.04
65 INT290375 Binding of Scarb1 and Gopc 1 0.15 0.29 0.04
66 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03
67 INT213002 Binding of Scarb1 and Trib3 1 0.00 1.02 0.03
68 INT262177 Nr1i2 Positive_regulation of Cd36 1 0.16 0.18 0.03
69 INT213011 Binding of Scarb1 and Hdl1 1 0.13 0.96 0.03
70 INT186186 LDLR Regulation of SCARB1 1 0.08 0.65 0.03
71 INT239345 Apoa1 Positive_regulation of RCT 1 0.02 1.15 0.03
72 INT308658 Binding of Apoa2 and Apoe 1 0.17 0.15 0.03
73 INT229008 MIA3 Positive_regulation of Gene_expression of Cd36 1 0.02 0.49 0.03
74 INT247155 Binding of Phb2 and Scarb1 1 0.01 0.33 0
75 INT186190 OLR1 Positive_regulation of SCARB1 1 0.01 0.67 0
76 INT10903 Apoa2 Positive_regulation of Nppb 1 0.08 0.17 0
77 INT239332 Hdl1 Positive_regulation of Gene_expression of Apoa1 1 0.04 0.84 0
78 INT283630 Cd36 Regulation of Positive_regulation of Ie 1 0.00 0 0
79 INT214472 Binding of LPL and GPIHBP1 1 0.29 1.17 0
80 INT47454 ras Positive_regulation of Apoa2 1 0.12 0.21 0
81 INT247444 Binding of APOA1 and APOC3 1 0.28 0.39 0
82 INT260519 Binding of Prnp and Scarb1 1 0.41 0.21 0
83 INT10907 Apoa2 Positive_regulation of Localization of Nppb 1 0.09 0.23 0
84 INT213017 Apoa1 Negative_regulation of Positive_regulation of Gtf3a 1 0.00 1.16 0
85 INT290374 Binding of Scarb1 and Ncapg2 1 0.23 0.43 0
86 INT247436 Binding of APOA1 and SACM1L 1 0.27 0.39 0
87 INT290193 Binding of APOA1 and Hdl1 1 0.01 1 0
88 INT260520 Binding of Myc and Scarb1 1 0.33 0.16 0
89 INT278242 MSC Regulation of Gene_expression of Cd36 1 0.08 1.17 0
90 INT239353 CETP Regulation of Apoa1 1 0.16 0.65 0
91 INT186189 LDLR Positive_regulation of Gene_expression of SCARB1 1 0.14 1.27 0
92 INT239342 Lcat Regulation of Apoa1 1 0.16 0.65 0
93 INT290373 Binding of Cd36 and Scarb1 1 0.11 0 0
94 INT339702 TRO Positive_regulation of CD36 1 0.08 1.06 0
95 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
96 INT326058 Negative_regulation of PRKCA Negative_regulation of APOA1 1 0.15 0.32 0
97 INT326059 APOA1 Positive_regulation of Gene_expression of APOE 1 0.61 0.38 0
98 INT326064 APOA1 Positive_regulation of HMGCR 1 0.16 0.19 0
99 INT213043 Regulation of Binding of Apoa1 and Scarb1 1 0.05 1.12 0
100 INT232003 Cd36 Positive_regulation of Transcription of Fasl 1 0.10 0.66 0
101 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0
102 INT239319 Pltp Regulation of Apoa1 1 0.22 0.65 0
103 INT283631 Positive_regulation of Binding of Cd36 and Ie 1 0.00 0 0
104 INT326057 APOA1 Regulation of Localization of APOE 1 0.54 1.36 0
105 INT290372 Binding of Ngfr and Scarb1 1 0.01 0.48 0
106 INT300197 Binding of APOA1 and C1S 1 0.39 3.56 0
107 INT239350 Eef1a2 Positive_regulation of Apoa1 1 0.22 0.86 0
108 INT283629 Binding of Cd36 and Ie 1 0.00 0 0
109 INT247440 Binding of APOA1 and APOB 1 0.28 1.02 0
110 INT304270 Binding of Apoa1 and Scarb1 1 0.00 0.39 0
111 INT185161 Binding of APOA2 and Retn 1 0.03 1.01 0
112 INT326066 APOA1 Positive_regulation of Positive_regulation of HMGCR 1 0.17 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for high-density lipoprotein particle binding. They are ordered first by their pain relevance and then by number of times they were reported in high-density lipoprotein particle binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23
2 INT142621 Positive_regulation of Gene_expression of CD36 38 0.70 15.18 13.4
3 INT209866 Regulation of Gene_expression of CD36 27 0.60 10.04 8.42
4 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21
5 INT19146 Negative_regulation of Apoa2 19 0.36 5.34 6.73
6 INT164656 Negative_regulation of Gene_expression of CD36 24 0.57 6.51 5.39
7 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04
8 INT136754 Gene_expression of SCARB1 64 0.77 43.28 4.82
9 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56
10 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08
11 INT26702 Transcription of CD36 17 0.70 3.56 3.49
12 INT10830 Regulation of Apoa1 11 0.44 15.1 3.04
13 INT10556 Regulation of Apoa2 5 0.44 0.51 2.8
14 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64
15 INT181880 Positive_regulation of Apoa1 19 0.66 21.19 2.43
16 INT198662 Positive_regulation of CD36 14 0.68 7.73 2.36
17 INT2452 Localization of Apoa2 9 0.55 0 2.3
18 INT26706 Positive_regulation of Transcription of CD36 8 0.68 3.32 2.12
19 INT49313 Positive_regulation of Gene_expression of Apoa1 3 0.68 9.55 2.01
20 INT94285 Negative_regulation of CD36 10 0.43 6.61 1.98
21 INT199084 Gene_expression of Cd36 31 0.53 16.94 1.94
22 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86
23 INT21813 Gene_expression of Apoa2 10 0.61 3.68 1.81
24 INT136752 Positive_regulation of Gene_expression of SCARB1 5 0.69 10.63 1.76
25 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67
26 INT156484 Binding of Apoa1 4 0.47 6.78 1.63
27 INT181881 Positive_regulation of Gene_expression of Apoa1 13 0.48 14.31 1.45
28 INT181882 Localization of Apoa1 8 0.71 7.94 1.37
29 INT73938 Gene_expression of Cd36 20 0.76 12.27 1.35
30 INT215380 Positive_regulation of Gene_expression of Cd36 12 0.47 8.51 1.3
31 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11
32 INT73939 Negative_regulation of Cd36 7 0.57 6.3 0.95
33 INT211557 Gene_expression of Scarb1 30 0.75 5.03 0.94
34 INT294479 Gene_expression of Scarb1 1 0.02 3.08 0.9
35 INT180451 Positive_regulation of Apoa2 15 0.67 12.65 0.89
36 INT72672 Positive_regulation of Gene_expression of APOA1 4 0.67 3.81 0.89
37 INT181885 Binding of Apoa1 7 0.35 5.66 0.84
38 INT178485 Binding of Cd36 11 0.22 6.65 0.8
39 INT136753 Regulation of Gene_expression of SCARB1 2 0.60 7.79 0.77
40 INT27077 Binding of CD36 4 0.37 2.14 0.72
41 INT136751 Negative_regulation of SCARB1 6 0.43 2.65 0.7
42 INT25374 Negative_regulation of Negative_regulation of Apoa2 1 0.30 0.24 0.67
43 INT136755 Negative_regulation of Gene_expression of SCARB1 2 0.57 6.61 0.63
44 INT212959 Binding of Scarb1 12 0.35 7.7 0.61
45 INT181888 Regulation of Apoa1 5 0.26 5.07 0.6
46 INT213118 Negative_regulation of Gene_expression of Apoa1 2 0.42 2.86 0.6
47 INT142620 Regulation of CD36 6 0.62 0.72 0.54
48 INT10983 Binding of Apoa2 7 0.45 4.21 0.52
49 INT20239 Regulation of APOA1 10 0.60 10.98 0.51
50 INT136757 Regulation of SCARB1 4 0.27 1.96 0.48
51 INT43397 Positive_regulation of Localization of Apoa2 1 0.09 0 0.48
52 INT190882 Regulation of Gene_expression of Apoa1 4 0.23 3.67 0.43
53 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41
54 INT280670 Localization of Cd36 1 0.61 0.65 0.41
55 INT280675 Regulation of Localization of Cd36 1 0.32 0.57 0.41
56 INT190691 Negative_regulation of APOA1 12 0.42 15.9 0.39
57 INT181883 Negative_regulation of Negative_regulation of Apoa1 1 0.40 1.24 0.39
58 INT126571 Positive_regulation of Cd36 3 0.41 1.19 0.38
59 INT72673 Transcription of APOA1 2 0.52 1.2 0.36
60 INT261209 Localization of Apoa1 4 0.73 2.61 0.33
61 INT16855 Binding of Scarb1 1 0.21 0 0.33
62 INT16856 Positive_regulation of Binding of Scarb1 1 0.27 0 0.33
63 INT47453 Positive_regulation of Positive_regulation of Apoa2 3 0.31 1.17 0.32
64 INT10801 Localization of CD36 3 0.73 2.12 0.32
65 INT209865 Negative_regulation of Transcription of CD36 1 0.57 0.15 0.32
66 INT307779 Positive_regulation of Localization of Apoa1 1 0.49 0.88 0.31
67 INT189968 Binding of APOA1 12 0.47 10.1 0.3
68 INT43396 Regulation of Localization of Apoa2 1 0.09 0 0.3
69 INT233881 Positive_regulation of Cd36 8 0.48 4.68 0.29
70 INT178326 Gene_expression of Pon1 1 0.67 2.93 0.28
71 INT325017 Localization of Pon1 1 0.46 1.37 0.28
72 INT178329 Negative_regulation of Gene_expression of Pon1 1 0.43 0.93 0.28
73 INT344673 Positive_regulation of Binding of Scarb1 1 0.16 0.82 0.28
74 INT297322 Binding of Apoa2 3 0.36 1.7 0.27
75 INT66978 Binding of Pon1 2 0.48 6.13 0.27
76 INT67227 Positive_regulation of Binding of Apoa2 2 0.26 1.31 0.25
77 INT2450 Negative_regulation of Positive_regulation of Apoa2 1 0.21 0 0.24
78 INT178328 Positive_regulation of Pon1 2 0.50 2.2 0.22
79 INT307183 Positive_regulation of Gene_expression of Scarb1 1 0.07 0.93 0.22
80 INT2449 Negative_regulation of Localization of Apoa2 1 0.19 0 0.22
81 INT323965 Protein_catabolism of Apoa2 1 0.01 0.34 0.22
82 INT186199 Binding of SCARB1 3 0.37 5.25 0.21
83 INT180454 Negative_regulation of Apoa2 6 0.42 7.42 0.2
84 INT190874 Negative_regulation of Gene_expression of Apoa1 1 0.15 0.9 0.2
85 INT10984 Negative_regulation of Binding of Apoa2 2 0.35 0.7 0.19
86 INT239275 Regulation of Localization of Apoa1 1 0.19 1.62 0.18
87 INT290336 Negative_regulation of Scarb1 4 0.31 1.77 0.17
88 INT211552 Localization of Scarb1 3 0.60 1.27 0.17
89 INT67225 Positive_regulation of Gene_expression of Apoa2 2 0.28 1.3 0.17
90 INT297577 Localization of APOA1 12 0.65 4.58 0.15
91 INT252219 Negative_regulation of Binding of Apoa1 1 0.16 0.95 0.15
92 INT59956 Positive_regulation of SCARB1 3 0.49 0.99 0.12
93 INT264861 Regulation of Apoa2 5 0.44 4.25 0.11
94 INT190693 Negative_regulation of Regulation of APOA1 1 0.09 1.94 0.11
95 INT279650 Transcription of Apoa2 1 0.02 0.79 0.1
96 INT279651 Positive_regulation of Transcription of Apoa2 1 0.02 0.84 0.1
97 INT180452 Localization of Apoa2 2 0.73 2.83 0.09
98 INT209861 Regulation of Transcription of CD36 1 0.44 0 0.09
99 INT67224 Negative_regulation of Gene_expression of Apoa2 1 0.32 0.47 0.08
100 INT178330 Regulation of Pon1 1 0.62 2.39 0.08
101 INT199067 Negative_regulation of Gene_expression of Cd36 3 0.28 0.9 0.07
102 INT282084 Negative_regulation of Gene_expression of Apoa2 1 0.04 1.17 0.07
103 INT67226 Regulation of Gene_expression of Apoa2 1 0.15 0.51 0.07
104 INT35232 Regulation of Positive_regulation of Apoa2 1 0.48 0.18 0.05
105 INT233879 Negative_regulation of Positive_regulation of Cd36 1 0.12 0.81 0.05
106 INT335124 Positive_regulation of APOA2 1 0.15 0.43 0.05
107 INT196696 Negative_regulation of Cd36 5 0.18 5.5 0.04
108 INT206043 Transcription of Cd36 4 0.37 2.59 0.04
109 INT242952 Regulation of Gene_expression of Cd36 1 0.31 0.71 0.04
110 INT290345 Negative_regulation of Gene_expression of Scarb1 1 0.42 0.5 0.04
111 INT335114 Negative_regulation of Transcription of APOA1 1 0.16 0.46 0.04
112 INT142622 Positive_regulation of Regulation of CD36 2 0.47 0.14 0.03
113 INT290334 Negative_regulation of Binding of Scarb1 1 0.31 0.12 0.03
114 INT255452 Negative_regulation of Gene_expression of APOA1 1 0.41 2.46 0.03
115 INT325024 Regulation of Gene_expression of Apoa2 1 0.21 1.23 0.03
116 INT272182 Transcription of Cd36 3 0.56 1.45 0
117 INT206050 Positive_regulation of Transcription of Cd36 3 0.32 1.72 0
118 INT272181 Positive_regulation of Transcription of Cd36 2 0.41 0.75 0
119 INT236559 Regulation of Cd36 2 0.42 0.65 0
120 INT280644 Positive_regulation of Gene_expression of Cd36 2 0.49 0.96 0
121 INT267959 Negative_regulation of Positive_regulation of APOA1 2 0.41 1.4 0
122 INT308624 Positive_regulation of Gene_expression of Apoa2 1 0.49 0.49 0
123 INT339735 Regulation of Localization of CD36 1 0.22 0.09 0
124 INT326078 Positive_regulation of Negative_regulation of APOA1 1 0.40 0.32 0
125 INT326072 Negative_regulation of Localization of APOA1 1 0.34 0.38 0
126 INT280642 Negative_regulation of Gene_expression of Cd36 1 0.35 0.08 0
127 INT255448 Positive_regulation of Binding of APOA1 1 0.48 2.88 0
128 INT202320 Protein_catabolism of Cd36 1 0.96 0.3 0
129 INT180453 Positive_regulation of Localization of Apoa2 1 0.49 1.84 0
130 INT255449 Positive_regulation of Positive_regulation of APOA1 1 0.48 1.44 0
131 INT309803 Negative_regulation of Binding of Apoa2 1 0.41 1.02 0
132 INT178327 Regulation of Binding of Pon1 1 0.45 0.91 0
133 INT256244 Positive_regulation of Regulation of Cd36 1 0.32 0.7 0
134 INT178331 Negative_regulation of Binding of Pon1 1 0.43 0.97 0
135 INT326079 Regulation of Localization of APOA1 1 0.36 0.24 0
136 INT271827 Regulation of Cd36 1 0.18 0.94 0
137 INT186198 Positive_regulation of Transcription of SCARB1 1 0.49 0.67 0
138 INT213117 Negative_regulation of Positive_regulation of Apoa1 1 0.07 0.54 0
139 INT290350 Transcription of Scarb1 1 0.50 0.24 0
140 INT214477 Negative_regulation of GPIHBP1 1 0.43 0.56 0
141 INT308631 Negative_regulation of Positive_regulation of Apoa2 1 0.42 0.5 0
142 INT309802 Positive_regulation of Binding of Apoa2 1 0.49 1.03 0
143 INT326068 Positive_regulation of Localization of APOA1 1 0.40 1.76 0
144 INT288894 Regulation of Localization of Apoa1 1 0.14 0.42 0
145 INT290341 Positive_regulation of Negative_regulation of Scarb1 1 0.32 0.69 0
146 INT339738 Positive_regulation of Localization of CD36 1 0.25 0.14 0
147 INT212958 Positive_regulation of Scarb1 1 0.20 1.29 0
148 INT213135 Negative_regulation of Scarb1 1 0.02 2.06 0
149 INT203725 Localization of Cd36 1 0.43 0.81 0
150 INT206044 Protein_catabolism of Cd36 1 0.12 0.46 0
151 INT186195 Transcription of SCARB1 1 0.70 1.42 0
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