GO:0008060

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Name ARF GTPase activator activity
Categary Function
Go Slim No
Go Link GO:0008060
Unique Molecular Interactions 32
Total Molecular Interactions 44
Total Single Events 257
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ARF GTPase activator activity. They are ordered first by their pain relevance and then by number of times they were reported for ARF GTPase activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133937 Binding of OPRK1 and ARFGEF1 1 0.01 0 1.39
2 INT201241 Positive_regulation of GDI2 Positive_regulation of Regulation of AGFG1 1 0.01 0 0.82
3 INT133941 ARFGEF1 Positive_regulation of OPRK1 1 0.02 0 0.76
4 INT133940 Binding of OPRD1 and ARFGEF1 1 0.02 0 0.73
5 INT133938 Binding of OPRL1 and ARFGEF1 1 0.00 0 0.73
6 INT133942 Binding of YY1 and ARFGEF1 1 0.05 0 0.69
7 INT168791 Positive_regulation of Binding of AGFG1 and IVNS1ABP 1 0.01 0.39 0.26
8 INT168792 Negative_regulation of Binding of AGFG1 and IVNS1ABP 1 0.01 0.39 0.26
9 INT168790 Binding of AGFG1 and IVNS1ABP 1 0.01 0.39 0.26
10 INT277705 SMAP2 Regulation of TNF 1 0.01 1.23 0.25
11 INT189674 CHKB Negative_regulation of ASAP1 1 0.08 0 0.24
12 INT64967 Binding of AGFG1 and Alb 1 0.01 0.2 0.2
13 INT206424 Binding of NFIA and ASAP1 1 0.33 0 0.13
14 INT347806 Binding of MOCS1 and SMAP2 1 0.00 0.48 0.12
15 INT64966 Binding of AGFG1 and Cd24 1 0.00 0.1 0.1
16 INT213207 Negative_regulation of ASAP2 Negative_regulation of PVR 1 0.01 0.45 0.04
17 INT250780 IRF6 Positive_regulation of ASAP1 1 0.06 0.34 0.04
18 INT239402 Binding of NPPA and ASAP1 1 0.19 1.24 0.04
19 INT213206 ASAP2 Negative_regulation of PVR 1 0.01 0.44 0.04
20 INT206428 Binding of SULT1B1 and ASAP1 1 0.28 0.13 0.03
21 INT206426 Binding of SULT4A1 and ASAP1 1 0.41 0 0
22 INT206085 FDPS Positive_regulation of AGFG1 1 0.00 0.4 0
23 INT156682 ASAP1 Negative_regulation of Gene_expression of TIMP1 1 0.17 0.07 0
24 INT206425 Binding of SULT1C2 and ASAP1 1 0.30 0 0
25 INT298853 Binding of AGFG1 and RILP 1 0.02 0.21 0
26 INT298866 Binding of AGFG1 and RAB7A 1 0.04 0.21 0
27 INT206419 SULT4A1 Positive_regulation of Binding of ASAP1 1 0.43 0 0
28 INT234790 B4GALNT1 Positive_regulation of AGFG1 1 0.00 0.08 0
29 INT234794 Binding of GDI1 and AGFG1 1 0.01 0 0
30 INT336468 Binding of CTS and ADAP1 1 0.02 0.42 0
31 INT206423 ASAP1 Positive_regulation of SULT4A1 1 0.59 0 0
32 INT298852 Binding of AGFG1 and MTG1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ARF GTPase activator activity. They are ordered first by their pain relevance and then by number of times they were reported in ARF GTPase activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133953 Gene_expression of ARFGEF1 1 0.07 0 3.87
2 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2
3 INT45168 Negative_regulation of ASAP1 23 0.58 10.15 2.44
4 INT45167 Positive_regulation of ASAP1 32 0.60 17.09 1.84
5 INT92941 Binding of ASAP1 24 0.39 12.38 1.25
6 INT201261 Regulation of AGFG1 4 0.09 2.72 0.9
7 INT43947 Localization of ASAP1 11 0.68 4.49 0.88
8 INT234820 Localization of AGFG1 3 0.14 0.86 0.74
9 INT156685 Regulation of ASAP1 8 0.22 1.94 0.71
10 INT55003 Regulation of Gene_expression of ASAP1 2 0.39 0 0.64
11 INT133947 Positive_regulation of Localization of ARFGEF1 1 0.05 0 0.62
12 INT133948 Localization of ARFGEF1 1 0.09 0 0.62
13 INT57163 Gene_expression of AGFG1 11 0.75 2.45 0.48
14 INT213221 Negative_regulation of ASAP2 1 0.01 5.83 0.46
15 INT64965 Binding of AGFG1 8 0.10 3.53 0.45
16 INT189743 Phosphorylation of ASAP1 2 0.58 0.16 0.31
17 INT213214 Positive_regulation of ASAP2 1 0.01 4.59 0.31
18 INT162374 Negative_regulation of Positive_regulation of ASAP1 2 0.12 0.71 0.21
19 INT162373 Regulation of Localization of ASAP1 1 0.18 0.36 0.17
20 INT162375 Regulation of Positive_regulation of ASAP1 1 0.08 0.45 0.17
21 INT213220 Regulation of ASAP2 1 0.01 1.73 0.15
22 INT162006 Positive_regulation of Gene_expression of ASAP1 7 0.44 3.3 0.13
23 INT213212 Localization of ASAP2 1 0.01 0.78 0.13
24 INT347808 Binding of SMAP2 1 0.00 0.47 0.12
25 INT162005 Negative_regulation of Gene_expression of ASAP1 2 0.31 1.05 0.1
26 INT234814 Positive_regulation of AGFG1 6 0.10 2.33 0.07
27 INT206463 Positive_regulation of Positive_regulation of ASAP1 4 0.41 1.28 0.07
28 INT214456 Gene_expression of SMAP2 1 0.06 1.09 0.05
29 INT186460 Transcription of ASAP1 5 0.56 3.02 0.03
30 INT298889 Negative_regulation of AGFG1 1 0.04 0.64 0.03
31 INT206432 Negative_regulation of Binding of ASAP1 1 0.35 0.1 0.03
32 INT234821 Positive_regulation of Gene_expression of AGFG1 1 0.10 0.07 0
33 INT336472 Gene_expression of ADAP1 1 0.03 0.08 0
34 INT170063 Positive_regulation of Regulation of ASAP1 1 0.12 0 0
35 INT336471 Binding of ADAP1 1 0.02 0.08 0
36 INT92940 Positive_regulation of Binding of ASAP1 1 0.42 1.05 0
37 INT336475 Negative_regulation of ADAP1 1 0.02 0.1 0
38 INT162376 Positive_regulation of Localization of ASAP1 1 0.14 0 0
39 INT234819 Regulation of Binding of AGFG1 1 0.05 0.19 0
40 INT234826 Positive_regulation of Regulation of AGFG1 1 0.10 0.87 0
41 INT336474 Positive_regulation of Negative_regulation of ADAP1 1 0.02 0.1 0
42 INT234818 Positive_regulation of Binding of AGFG1 1 0.10 0.08 0
43 INT298916 Regulation of Gene_expression of AGFG1 1 0.04 0 0
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