GO:0008066

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Name glutamate receptor activity
Categary Function
Go Slim No
Go Link GO:0008066
Unique Molecular Interactions 26
Total Molecular Interactions 35
Total Single Events 309
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for glutamate receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for glutamate receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9
2 INT157524 Binding of GRM5 and OPRM1 1 0.36 0 1.74
3 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
4 INT136255 Tff3 Regulation of GRIA1 1 0.00 0.18 1.24
5 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
6 INT169082 Binding of GRIA1 and MOCOS 2 0.07 1.23 1.17
7 INT157522 GRM5 Regulation of Gene_expression of OPRM1 1 0.28 0 0.97
8 INT282139 Grm1 Regulation of Grip2 1 0.00 0.62 0.69
9 INT197240 Grik2 Regulation of Gene_expression of Gabrg1 1 0.08 0.13 0.64
10 INT197236 Grik2 Regulation of Gabrg1 1 0.08 0.13 0.64
11 INT282142 Grm1 Positive_regulation of Positive_regulation of Trib3 1 0.01 0.27 0.57
12 INT312751 Phosphorylation of Gria1 Positive_regulation of GRIA1 1 0.18 0.22 0.55
13 INT322811 Binding of GRIA1 and RS1 1 0.00 0.43 0.51
14 INT159774 Binding of GRM5 and TRPV1 1 0.40 0.5 0.51
15 INT160971 Gm2111 Positive_regulation of Grm7 1 0.01 0.16 0.41
16 INT322810 SLC12A1 Regulation of Binding of GRIA1 1 0.00 0.39 0.36
17 INT349951 Grm7 Regulation of pcp 1 0.00 0.56 0.28
18 INT264841 NAMPT Positive_regulation of GRM5 1 0.01 0.72 0.27
19 INT197232 Binding of Grik5 and Kars 1 0.17 0.1 0.25
20 INT241967 Binding of Grm7 and Acpt 1 0.17 0 0.16
21 INT272365 Gene_expression of Adarb1 Positive_regulation of Gene_expression of GRIA1 1 0.00 0.26 0.09
22 INT272600 Binding of Dlg4 and Grik5 1 0.20 0 0.03
23 INT272601 Binding of Dlg4 and Grik2 1 0.22 0 0.03
24 INT282504 Binding of Grik2 and Grik3 1 0.27 0.61 0
25 INT282507 Binding of Grik3 and ocd 1 0.25 0.61 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for glutamate receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in glutamate receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48055 Gene_expression of Grm1 27 0.78 14.29 17.01
2 INT100919 Positive_regulation of Grm1 21 0.70 7.82 11.55
3 INT73544 Gene_expression of Grm7 34 0.64 31.28 8.04
4 INT147498 Gene_expression of GRM5 10 0.75 3.16 7.12
5 INT113153 Regulation of Grm1 6 0.44 4.11 5.41
6 INT100920 Positive_regulation of Gene_expression of Grm1 7 0.70 5.88 4.87
7 INT91055 Negative_regulation of Grm1 7 0.45 5.14 4.87
8 INT79682 Gene_expression of Grm7 6 0.75 4.74 4.5
9 INT115074 Positive_regulation of GRIA1 10 0.67 2.66 4.48
10 INT48784 Gene_expression of GRIA1 12 0.78 3.25 4.11
11 INT74814 Binding of Grm1 5 0.45 2.69 4.1
12 INT48786 Phosphorylation of GRIA1 7 0.80 1.89 3.91
13 INT79680 Binding of Grm7 6 0.47 2.83 3.58
14 INT123978 Binding of GRIA1 3 0.41 3.5 2.62
15 INT140206 Binding of GRM5 6 0.36 1.85 2.52
16 INT157529 Positive_regulation of GRM5 3 0.48 0.59 2.07
17 INT98927 Localization of Grm1 4 0.71 0.42 1.97
18 INT48787 Regulation of GRIA1 5 0.27 1.28 1.88
19 INT122435 Positive_regulation of Grm7 3 0.00 1.89 1.79
20 INT79683 Negative_regulation of Grm7 3 0.41 2.22 1.75
21 INT124667 Negative_regulation of Grik2 4 0.41 2.06 1.7
22 INT100523 Regulation of GRM5 2 0.26 0.49 1.51
23 INT124669 Gene_expression of Grik2 6 0.75 1.66 1.47
24 INT136251 Regulation of Positive_regulation of GRIA1 1 0.44 0.07 1.46
25 INT152371 Regulation of Gene_expression of Grm1 2 0.42 0.54 1.4
26 INT79681 Localization of Grm7 5 0.78 2.57 1.34
27 INT100921 Positive_regulation of Positive_regulation of Grm1 2 0.47 1.01 1.24
28 INT130323 Regulation of Grm7 3 0.26 1.9 1.21
29 INT131970 Regulation of Grik2 3 0.26 0.65 1.15
30 INT115075 Negative_regulation of Gene_expression of GRIA1 1 0.57 0 1.08
31 INT207773 Negative_regulation of GRIA1 2 0.57 0.85 0.97
32 INT157528 Regulation of Gene_expression of GRM5 1 0.43 0 0.96
33 INT158378 Transcription of Grm7 1 0.00 0.65 0.94
34 INT168534 Gene_expression of Grik5 3 0.38 0.64 0.9
35 INT115077 Regulation of Gene_expression of GRIA1 3 0.45 0.44 0.88
36 INT223641 Transcription of Grm1 3 0.69 1.4 0.83
37 INT131967 Transcription of Grik2 2 0.67 0.73 0.82
38 INT131966 Regulation of Regulation of Grik2 1 0.26 0.45 0.75
39 INT157526 Regulation of Binding of GRM5 1 0.43 0 0.73
40 INT115076 Negative_regulation of Positive_regulation of GRIA1 1 0.41 0.26 0.72
41 INT91056 Negative_regulation of Gene_expression of Grm7 2 0.18 1.21 0.69
42 INT235561 Localization of GRIA1 2 0.06 0.37 0.68
43 INT345211 Positive_regulation of Grm7 1 0.02 0.64 0.66
44 INT154199 Regulation of Localization of Grm7 1 0.60 0.92 0.62
45 INT353901 Negative_regulation of Negative_regulation of Grm1 1 0.40 0.67 0.61
46 INT91054 Negative_regulation of Gene_expression of Grm1 2 0.36 0.19 0.59
47 INT120995 Positive_regulation of Gene_expression of Grm7 1 0.00 0.57 0.57
48 INT201278 Gene_expression of Grik3 1 0.41 0.55 0.52
49 INT149425 Transcription of GRIA1 3 0.52 0.66 0.46
50 INT235562 Positive_regulation of Localization of GRIA1 1 0.01 0.37 0.46
51 INT168536 Localization of Grik5 1 0.07 0.09 0.34
52 INT168539 Regulation of Gene_expression of Grik5 1 0.02 0.09 0.34
53 INT147500 Positive_regulation of Gene_expression of GRM5 1 0.67 0.25 0.33
54 INT284758 Regulation of Grik3 1 0.17 0.07 0.33
55 INT223646 Regulation of Gene_expression of Grm7 1 0.01 4.41 0.32
56 INT115164 Positive_regulation of Phosphorylation of GRIA1 1 0.49 0.66 0.32
57 INT147499 Negative_regulation of Gene_expression of GRM5 1 0.41 0.29 0.26
58 INT223645 Positive_regulation of Gene_expression of Grm7 2 0.25 1.16 0.21
59 INT241959 Binding of Grm7 1 0.23 0 0.15
60 INT260482 Localization of Grm7 1 0.18 0.11 0.13
61 INT149424 Positive_regulation of Gene_expression of GRIA1 2 0.49 0.17 0.11
62 INT338884 Regulation of Grm7 1 0.13 0.42 0.09
63 INT338883 Positive_regulation of Regulation of Grm7 1 0.22 0.42 0.09
64 INT223642 Negative_regulation of Transcription of Grm1 1 0.57 0.65 0.08
65 INT124941 Negative_regulation of Gene_expression of Grik2 1 0.41 0 0
66 INT149423 Positive_regulation of Transcription of GRIA1 1 0.01 0.06 0
67 INT282476 Binding of Grik2 1 0.31 0.61 0
68 INT282480 Binding of Grik3 1 0.39 0.61 0
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