GO:0008081

From wiki-pain
Jump to: navigation, search
Name phosphoric diester hydrolase activity
Categary Function
Go Slim No
Go Link GO:0008081
Unique Molecular Interactions 144
Total Molecular Interactions 178
Total Single Events 1521
Pain Genes Associated 29

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phosphoric diester hydrolase activity. They are ordered first by their pain relevance and then by number of times they were reported for phosphoric diester hydrolase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT150232 Samhd1 Positive_regulation of Gene_expression of TNFSF13B 1 0.01 1.74 1.67
2 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49
3 INT96262 Positive_regulation of Pik3cd Positive_regulation of Plcg1 1 0.03 0 1.39
4 INT128776 Cntn1 Positive_regulation of Gene_expression of Pde6b 1 0.02 0.55 1.26
5 INT96261 Positive_regulation of Pik3cd Positive_regulation of Plcg2 1 0.02 0 1.21
6 INT152428 Ghrh Positive_regulation of Pde6b 1 0.07 0.5 1.18
7 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08
8 INT96260 Pik3cd Regulation of Plcg2 1 0.02 0 0.92
9 INT55564 Binding of Oprk1 and Pde6b 1 0.01 0 0.92
10 INT48341 Negative_regulation of Pde8a Regulation of Ahsg 1 0.22 0 0.9
11 INT48342 Pde8a Regulation of Ahsg 1 0.24 0 0.9
12 INT221257 Pde5a Positive_regulation of PRKG1 3 0.07 0.19 0.86
13 INT265566 Binding of PDE4D and PTPN5 1 0.03 0.81 0.85
14 INT257222 Binding of Ltp and Pde5a 2 0.07 0.14 0.75
15 INT314596 Isg15 Negative_regulation of Gene_expression of Samhd1 1 0.05 0.17 0.7
16 INT314597 Oasl1 Negative_regulation of Gene_expression of Samhd1 1 0.06 0.17 0.7
17 INT314595 Zbp1 Negative_regulation of Gene_expression of Samhd1 1 0.05 0.17 0.7
18 INT94089 Binding of Pnoc and Pde6b 1 0.02 0.09 0.57
19 INT273350 Pde7a Positive_regulation of Localization of Pde4d 1 0.33 1.35 0.49
20 INT127663 IRF6 Positive_regulation of PDE4A 1 0.14 0.76 0.48
21 INT127664 Negative_regulation of PDE4A Negative_regulation of MMP9 1 0.37 0.76 0.48
22 INT127665 Negative_regulation of PDE4A Negative_regulation of Transcription of MMP9 1 0.37 0.76 0.48
23 INT127662 Negative_regulation of PDE4A Negative_regulation of Gene_expression of PTGS2 1 0.15 0.75 0.47
24 INT222923 Negative_regulation of Pde4a Negative_regulation of Positive_regulation of Mpo 1 0.04 0.59 0.45
25 INT222924 Negative_regulation of Pde4a Negative_regulation of Gene_expression of Il12a 1 0.01 0.59 0.45
26 INT222922 Negative_regulation of Pde4a Negative_regulation of Gene_expression of Il1 1 0.01 0.56 0.44
27 INT94092 Pnoc Positive_regulation of Pde6b 1 0.02 0.1 0.44
28 INT152430 Regulation of Ghrh Positive_regulation of Pde6b 1 0.04 0.16 0.43
29 INT275100 Pde4a Negative_regulation of RTP3 1 0.00 0.51 0.42
30 INT275087 Pde2a Negative_regulation of stm 1 0.01 0.51 0.42
31 INT275089 Pde4a Negative_regulation of stm 1 0.02 0.51 0.42
32 INT275104 Pde2a Negative_regulation of RTP3 1 0.00 0.51 0.42
33 INT257229 Binding of PRKG1 and Pde5a 1 0.01 0.17 0.41
34 INT275099 Pde9a Negative_regulation of RTP3 1 0.00 0.51 0.39
35 INT275093 Pde9a Negative_regulation of stm 1 0.00 0.51 0.39
36 INT152426 Ghrh Positive_regulation of Positive_regulation of Pde6b 1 0.07 0.14 0.38
37 INT273172 Negative_regulation of PDE4A Negative_regulation of Localization of CD4 1 0.11 0.74 0.37
38 INT221259 Pde5a Positive_regulation of Localization of PRKG1 1 0.00 0.06 0.37
39 INT275096 Pde9a Regulation of Ltp 1 0.00 0.11 0.35
40 INT275098 Pde9a Regulation of RTP3 1 0.00 0.11 0.35
41 INT275094 Pde5a Regulation of Ltp 1 0.05 0 0.35
42 INT274172 Negative_regulation of Pde4a Negative_regulation of Positive_regulation of TNF 1 0.02 0.72 0.28
43 INT273352 Pde7a Positive_regulation of Localization of Pde4b 1 0.43 0.68 0.24
44 INT235125 PDE2A Negative_regulation of Twist1 1 0.00 0.99 0.24
45 INT101312 Samhd1 Positive_regulation of Gene_expression of Aif1 1 0.03 0.38 0.23
46 INT257224 Pde5a Positive_regulation of Phosphorylation of Creb1 1 0.03 0.09 0.2
47 INT163055 Negative_regulation of Pde10a Positive_regulation of Gene_expression of Qrfp 1 0.03 0 0.2
48 INT30071 Gm8212 Regulation of Pde3a 1 0.00 0 0.2
49 INT196822 Negative_regulation of Adcy5 Positive_regulation of Pde1a 1 0.01 0 0.19
50 INT196815 Adcy5 Positive_regulation of Pde1a 1 0.01 0 0.19
51 INT202297 Pde5a Positive_regulation of Prkg1 1 0.00 0.13 0.18
52 INT262361 Binding of Pde4b and DISC1 1 0.08 0.57 0.18
53 INT274169 Mapk1 Regulation of Pde4a 1 0.05 0.62 0.17
54 INT276065 Camk2a Negative_regulation of Pde1b 1 0.56 0 0.17
55 INT219601 Pde4a Negative_regulation of Twist1 1 0.10 0 0.16
56 INT226365 Negative_regulation of PDE4A Negative_regulation of Localization of IL5 1 0.05 0.18 0.16
57 INT225501 Plcl1 Regulation of Gene_expression of Casr 1 0.04 0.67 0.16
58 INT219598 Pde4a Negative_regulation of Gene_expression of Twist1 1 0.10 0 0.16
59 INT226382 Negative_regulation of PDE4A Negative_regulation of Localization of IL4 1 0.12 0.18 0.16
60 INT263179 PDE3A Regulation of COPD 1 0.00 1 0.15
61 INT219597 Prkaca Positive_regulation of Pde4d 1 0.29 0 0.15
62 INT263177 Binding of PDE3A and COPD 1 0.01 1 0.15
63 INT273171 PDE4A Regulation of IL8 1 0.05 0.53 0.15
64 INT276060 Pde1b Regulation of Car2 1 0.30 0 0.15
65 INT263176 Binding of PDE4A and COPD 1 0.01 1 0.15
66 INT196811 Binding of Pde1a and Adcy5 1 0.01 0 0.14
67 INT196837 Binding of CALM1 and Pde1a 1 0.00 0 0.14
68 INT89763 Positive_regulation of APEX1 Positive_regulation of Positive_regulation of NR4A1 1 0.10 0.87 0.14
69 INT135941 Positive_regulation of PDE2A Positive_regulation of Gene_expression of PRKG1 1 0.13 0.8 0.13
70 INT273185 PDE4A Regulation of Gene_expression of Mmp12 1 0.08 0.57 0.13
71 INT276079 Pde1b Negative_regulation of Camk2a 1 0.41 0 0.12
72 INT273019 Binding of PDE1A and MDD1 1 0.30 0.69 0.12
73 INT244032 Binding of Ppp1ca and Plcl1 1 0.00 0.16 0.12
74 INT219599 Pde4d Regulation of Prkaca 1 0.28 0 0.12
75 INT101310 Samhd1 Positive_regulation of Gene_expression of Aif1 1 0.04 0.19 0.12
76 INT273018 Binding of FGF9 and PDE1A 1 0.18 0.3 0.11
77 INT135943 Positive_regulation of PRKG1 Regulation of PDE2A 1 0.08 0.73 0.1
78 INT257217 Binding of Pde2a and Pde5a 1 0.03 0 0.1
79 INT303815 Binding of Igfals and Tdp1 1 0.11 1.68 0.1
80 INT219600 Pde4d Regulation of Binding of Prkaca 1 0.28 0 0.09
81 INT219602 Binding of Prkaca and Pde4d 1 0.23 0 0.09
82 INT79446 IL10 Negative_regulation of Transcription of PDE4B 1 0.44 0 0.08
83 INT148096 Vasp Regulation of Pde2a 1 0.00 0.23 0.08
84 INT257221 Negative_regulation of Binding of Src and Pde5a 1 0.03 0 0.08
85 INT79445 IL10 Negative_regulation of Gene_expression of PDE4B 1 0.43 0 0.08
86 INT98269 PDE2A Positive_regulation of PRKG1 1 0.07 0.57 0.08
87 INT257219 Binding of Src and Pde5a 1 0.02 0 0.08
88 INT98270 Positive_regulation of PDE2A Positive_regulation of PRKG1 1 0.07 0.57 0.08
89 INT276067 Binding of Car2 and Pde1b 1 0.32 0 0.06
90 INT276050 Binding of Calm3 and Pde1b 1 0.15 0 0.06
91 INT276049 Pde1b Regulation of Positive_regulation of Rpa1 1 0.04 0 0.06
92 INT145056 Binding of Nr1i3 and Plcl1 1 0.21 0.26 0.05
93 INT82578 IRF6 Positive_regulation of Gene_expression of PDE4B 1 0.21 0.09 0.05
94 INT273353 Pde4d Regulation of Gene_expression of Twist1 1 0.26 0.25 0.05
95 INT145057 Binding of Ppara and Plcl1 1 0.36 0.26 0.05
96 INT308432 Binding of PDE4A and Aip 1 0.05 3.1 0.05
97 INT263197 Binding of PDE3A and Pde5a 1 0.03 0.18 0.04
98 INT275090 Twist1 Positive_regulation of Gene_expression of Pde5a 1 0.02 0.62 0.04
99 INT275095 Twist1 Positive_regulation of Pde5a 1 0.03 0.62 0.04
100 INT276038 Camk2a Negative_regulation of Pde1a 1 0.14 0 0.03
101 INT263198 Pde5a Negative_regulation of PDE4A 1 0.09 0.16 0.03
102 INT276036 Negative_regulation of Pde1b Positive_regulation of Phosphorylation of Prkaca 1 0.27 0 0.03
103 INT325600 Nppa Positive_regulation of Pde2a 1 0.11 0.16 0.03
104 INT276055 Negative_regulation of Pde1b Positive_regulation of Prkaca 1 0.27 0 0.03
105 INT276070 Negative_regulation of Pde1b Positive_regulation of Phosphorylation of Ppp1r1b 1 0.24 0 0.03
106 INT219596 Binding of Pde4a and Pde4d 1 0.28 0.31 0
107 INT308425 Binding of Pde2a and Aip 1 0.04 1.37 0
108 INT325602 Binding of Ang and Pde2a 1 0.07 0.15 0
109 INT276044 Binding of Pde1b and Ppp1cc 1 0.12 0 0
110 INT313871 Pde5a Positive_regulation of Pah 1 0.49 0.97 0
111 INT276048 Binding of Pde1b and Myoz1 1 0.04 0 0
112 INT121478 Binding of Pde3a and Positive_regulation of Localization of Ins1 1 0.24 0 0
113 INT186239 Binding of ROS1 and Positive_regulation of PDE2A 1 0.00 0 0
114 INT79447 IRF6 Positive_regulation of Transcription of PDE4B 1 0.19 0 0
115 INT276078 Binding of Camk2a and Pde1b 1 0.36 0 0
116 INT276052 Negative_regulation of Pde1b Negative_regulation of Camk2a 1 0.41 0 0
117 INT303822 Tdp1 Regulation of TREH 1 0.02 0.92 0
118 INT186241 Gene_expression of ROS1 Positive_regulation of PDE2A 1 0.00 0 0
119 INT325603 Pde2a Regulation of Rgs2 1 0.03 0 0
120 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0
121 INT191577 Binding of Pde6b and Tst 1 0.02 0.48 0
122 INT275091 Negative_regulation of Twist1 Positive_regulation of Pde5a 1 0.02 0.06 0
123 INT242674 Binding of Pde6b and Ppp3cb 1 0.00 0.6 0
124 INT325613 Pls1 Regulation of Pde2a 1 0.00 0 0
125 INT330056 Bcl2 Regulation of Localization of Cyct 1 0.27 0.97 0
126 INT276058 Camk2a Regulation of Pde1b 1 0.26 0 0
127 INT276589 Binding of Iqgap1 and Plce1 1 0.19 0.34 0
128 INT213582 Binding of HSPA8 and PDE4B 1 0.33 0.3 0
129 INT325593 Pde2a Positive_regulation of Negative_regulation of Nppa 1 0.11 0 0
130 INT66168 Pde2a Negative_regulation of Adra2a 1 0.04 0 0
131 INT276582 Binding of Espn and Plce1 1 0.01 0.34 0
132 INT276042 Negative_regulation of Binding of Calm3 and Pde1b 1 0.17 0 0
133 INT325612 Rgs2 Regulation of Pde2a 1 0.10 0 0
134 INT325609 Pde2a Positive_regulation of Gene_expression of Rgs2 1 0.12 0 0
135 INT343716 Nos3 Positive_regulation of Pde6b 1 0.20 0 0
136 INT276047 Camk2a Regulation of Negative_regulation of Pde1b 1 0.43 0 0
137 INT276051 Pde1b Regulation of Regulation of Car2 1 0.30 0 0
138 INT276071 Pde1b Regulation of Positive_regulation of Camk2a 1 0.43 0 0
139 INT245039 Binding of Xrcc1 and Tdp1 1 0.39 0.77 0
140 INT308426 Binding of Pde4a and Aip 1 0.02 0.89 0
141 INT343718 Nos3 Regulation of Pde6b 1 0.10 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phosphoric diester hydrolase activity. They are ordered first by their pain relevance and then by number of times they were reported in phosphoric diester hydrolase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT30169 Negative_regulation of Pde4a 107 0.58 81 36.23
2 INT49850 Negative_regulation of PDE4A 105 0.58 76.91 26.59
3 INT209 Positive_regulation of Pde5a 30 0.21 2.54 16.31
4 INT48009 Gene_expression of Pde6b 38 0.68 15.03 11.41
5 INT96259 Positive_regulation of Plcg1 11 0.49 3.01 11.15
6 INT95207 Negative_regulation of Pde5a 46 0.58 32.01 10.14
7 INT105777 Gene_expression of Pde4a 30 0.76 12.67 8.52
8 INT160168 Gene_expression of Pde10a 10 0.74 8.66 7.94
9 INT110004 Gene_expression of Plcg1 7 0.41 2.61 7.87
10 INT79456 Gene_expression of PDE4A 35 0.77 19.42 7.42
11 INT118492 Regulation of Pde4a 7 0.61 6.32 6.04
12 INT188852 Gene_expression of Pde2a 13 0.19 6.44 5.35
13 INT105775 Gene_expression of Pde4d 31 0.78 4.18 5.21
14 INT127668 Positive_regulation of PDE4A 12 0.68 8.39 5.13
15 INT121471 Negative_regulation of Pde3a 24 0.34 13.79 4.73
16 INT73128 Regulation of Pde5a 7 0.37 4.42 4.27
17 INT119498 Positive_regulation of Pde6b 11 0.43 18.75 4.22
18 INT48008 Negative_regulation of Pde6b 9 0.15 6.12 4.11
19 INT101299 Gene_expression of Samhd1 8 0.41 4.01 3.86
20 INT172852 Localization of Cyct 28 0.78 21.42 3.34
21 INT73127 Gene_expression of Pde5a 18 0.76 5.25 3.31
22 INT75815 Positive_regulation of PDE2A 10 0.40 5.1 3.15
23 INT165915 Regulation of Negative_regulation of Pde4a 5 0.29 6.72 2.91
24 INT30172 Positive_regulation of Pde2a 3 0.39 0.55 2.77
25 INT172853 Positive_regulation of Localization of Cyct 14 0.67 10.48 2.65
26 INT98557 Regulation of PDE4A 12 0.44 8.42 2.56
27 INT303796 Gene_expression of Tdp1 1 0.77 70.15 2.55
28 INT1216 Negative_regulation of Pde4b 9 0.41 2.65 2.5
29 INT128773 Regulation of Gene_expression of Pde6b 4 0.45 1.41 2.5
30 INT137270 Positive_regulation of PDE4D 4 0.48 2.48 2.39
31 INT79402 Gene_expression of Pde4b 7 0.74 3 2.38
32 INT48007 Regulation of Pde6b 6 0.39 4.4 2.2
33 INT108422 Binding of Pde5a 11 0.36 3.07 2.07
34 INT105776 Negative_regulation of Gene_expression of Pde4d 5 0.59 2.2 2.01
35 INT110003 Phosphorylation of Plcg1 2 0.37 0.91 1.96
36 INT24909 Negative_regulation of Pde10a 4 0.43 0.87 1.87
37 INT64530 Negative_regulation of Positive_regulation of Pde2a 1 0.36 0 1.81
38 INT79401 Regulation of Gene_expression of Pde4b 4 0.59 1.26 1.8
39 INT153606 Localization of Pde4a 2 0.69 1.23 1.79
40 INT119905 Negative_regulation of PDE3A 5 0.18 5 1.77
41 INT12781 Regulation of Pde2a 4 0.23 1.14 1.69
42 INT135930 Regulation of Gene_expression of Pde4a 3 0.61 0.52 1.63
43 INT64529 Localization of Pde2a 1 0.59 0 1.63
44 INT135927 Positive_regulation of Pde4a 1 0.68 0 1.6
45 INT1580 Negative_regulation of Pde2a 7 0.52 3.26 1.59
46 INT177525 Negative_regulation of Negative_regulation of Pde4a 5 0.28 5.22 1.58
47 INT259631 Negative_regulation of PDE4B 4 0.10 4.88 1.54
48 INT188855 Positive_regulation of Gene_expression of Pde2a 5 0.12 1.97 1.53
49 INT79455 Positive_regulation of Gene_expression of PDE4A 3 0.67 2.07 1.5
50 INT14195 Localization of Pde2a 4 0.16 0.34 1.33
51 INT73126 Positive_regulation of Gene_expression of Pde5a 3 0.59 0.55 1.31
52 INT135924 Positive_regulation of Gene_expression of Pde4d 2 0.59 0 1.28
53 INT64562 Positive_regulation of Pde1a 2 0.06 0.28 1.28
54 INT177527 Negative_regulation of Binding of Pde4a 4 0.28 3.5 1.23
55 INT209138 Negative_regulation of Negative_regulation of PDE4A 4 0.42 3.84 1.21
56 INT110001 Binding of Plcg1 2 0.36 0.44 1.21
57 INT67852 Negative_regulation of Pde1a 1 0.25 0.18 1.2
58 INT40345 Positive_regulation of Pde4b 5 0.67 2.96 1.19
59 INT238533 Negative_regulation of Localization of Cyct 7 0.57 5.75 1.15
60 INT110400 Negative_regulation of Pde1b 21 0.50 0.58 1.14
61 INT79407 Positive_regulation of Gene_expression of Pde4b 1 0.67 0.38 1.13
62 INT79454 Gene_expression of PDE4B 12 0.77 1.72 1.11
63 INT219595 Positive_regulation of Gene_expression of Pde4a 3 0.39 2.81 1.11
64 INT105774 Negative_regulation of Gene_expression of Pde4a 3 0.42 0.4 1.03
65 INT139117 Negative_regulation of Gene_expression of PDE4A 4 0.42 2.28 1.02
66 INT110000 Positive_regulation of Phosphorylation of Plcg1 1 0.23 0.49 1.02
67 INT219589 Binding of Pde4d 13 0.47 0.51 1.01
68 INT7834 Gene_expression of Pde2a 5 0.51 1.9 1.01
69 INT219568 Positive_regulation of Pde4d 9 0.49 1.74 1
70 INT209144 Positive_regulation of PDE4B 4 0.45 2.03 0.95
71 INT160171 Localization of Pde10a 2 0.77 1.26 0.95
72 INT188851 Regulation of Gene_expression of Pde2a 1 0.04 0.75 0.94
73 INT257200 Phosphorylation of Pde5a 1 0.25 0 0.94
74 INT177531 Binding of Pde4a 4 0.29 2.46 0.91
75 INT48340 Regulation of Pde8a 1 0.16 0 0.91
76 INT1217 Regulation of Pde4b 1 0.06 0 0.9
77 INT163757 Negative_regulation of Phosphorylation of Samhd1 1 0.11 0.16 0.89
78 INT163754 Phosphorylation of Samhd1 1 0.15 0.16 0.89
79 INT127669 Regulation of Negative_regulation of PDE4A 4 0.45 2.74 0.88
80 INT263129 Positive_regulation of Negative_regulation of PDE4A 3 0.35 2.92 0.86
81 INT40344 Positive_regulation of Pde8a 1 0.55 1.16 0.85
82 INT265568 Binding of PDE4D 1 0.05 0.81 0.85
83 INT160408 Transcription of Samhd1 1 0.28 0.95 0.84
84 INT226473 Negative_regulation of PDE4D 5 0.19 3.54 0.83
85 INT89776 Positive_regulation of Pde2a 2 0.47 2.84 0.81
86 INT177532 Localization of Pde5a 2 0.56 0.96 0.81
87 INT135931 Regulation of Regulation of Pde4a 1 0.44 0 0.81
88 INT219578 Negative_regulation of Pde4d 3 0.46 2.95 0.8
89 INT135923 Regulation of Gene_expression of Pde4d 2 0.44 0 0.8
90 INT98275 Negative_regulation of PDE2A 4 0.17 3.96 0.79
91 INT177533 Negative_regulation of Binding of Pde3a 1 0.21 2.46 0.76
92 INT303799 Phosphorylation of Tdp1 1 0.82 22.84 0.71
93 INT183161 Regulation of Pde2a 2 0.05 0.5 0.67
94 INT235846 Transcription of Pde4a 2 0.30 0.88 0.66
95 INT257202 Protein_catabolism of Pde5a 2 0.38 0.36 0.66
96 INT208 Negative_regulation of Positive_regulation of Pde5a 3 0.17 2.02 0.65
97 INT162911 Gene_expression of PDE3A 2 0.24 2.47 0.65
98 INT219580 Localization of Pde4d 5 0.73 2.07 0.64
99 INT213617 Gene_expression of PDE4D 3 0.53 1.98 0.62
100 INT40343 Negative_regulation of Pde8a 2 0.46 1.11 0.6
101 INT275071 Negative_regulation of Protein_catabolism of Pde5a 1 0.17 0.36 0.6
102 INT110002 Regulation of Positive_regulation of Plcg1 1 0.11 0.4 0.59
103 INT303804 Localization of Tdp1 1 0.80 11.71 0.59
104 INT79398 Transcription of Pde4b 1 0.51 0.18 0.57
105 INT79403 Positive_regulation of Transcription of Pde4b 1 0.45 0.18 0.57
106 INT275078 Negative_regulation of Pde9a 1 0.01 1.38 0.57
107 INT75814 Regulation of Positive_regulation of PDE2A 1 0.23 0.26 0.56
108 INT126754 Binding of Pde6b 5 0.34 1.34 0.55
109 INT94088 Transcription of Pde6b 2 0.55 0.39 0.53
110 INT145053 Negative_regulation of Plcl1 4 0.52 1.65 0.5
111 INT219573 Positive_regulation of Localization of Pde4d 2 0.49 1.39 0.5
112 INT273179 Localization of PDE4D 1 0.34 2.01 0.5
113 INT209136 Regulation of Gene_expression of PDE4A 3 0.27 1.63 0.49
114 INT257211 Negative_regulation of Localization of Pde5a 1 0.13 0.2 0.48
115 INT273345 Gene_expression of Pde7a 1 0.65 1.45 0.47
116 INT222921 Protein_catabolism of Pde4a 1 0.07 1.78 0.47
117 INT152425 Positive_regulation of Positive_regulation of Pde6b 2 0.18 1.74 0.46
118 INT162903 Localization of PDE2A 2 0.61 0.89 0.45
119 INT121469 Binding of Pde3a 2 0.23 1.42 0.44
120 INT216759 Binding of PDE2A 1 0.00 0.08 0.44
121 INT119499 Regulation of Positive_regulation of Pde6b 2 0.11 0.8 0.43
122 INT273344 Negative_regulation of Pde7a 1 0.49 1.36 0.43
123 INT40342 Negative_regulation of Positive_regulation of Pde8a 1 0.46 0.58 0.42
124 INT79450 Positive_regulation of Gene_expression of PDE4B 6 0.50 0.6 0.41
125 INT103316 Localization of PDE4A 2 0.68 1.76 0.41
126 INT275079 Positive_regulation of Pde9a 1 0.01 0 0.41
127 INT219565 Regulation of Pde4d 3 0.44 0.5 0.39
128 INT273347 Negative_regulation of Gene_expression of Pde7a 1 0.36 1.3 0.38
129 INT275368 Gene_expression of Cyct 5 0.65 3.21 0.37
130 INT275370 Positive_regulation of Gene_expression of Cyct 1 0.49 1.62 0.37
131 INT209137 Negative_regulation of Positive_regulation of PDE4A 1 0.42 0.8 0.37
132 INT145049 Gene_expression of Plcl1 2 0.59 1.29 0.35
133 INT273330 Positive_regulation of Negative_regulation of Pde4d 1 0.39 1.25 0.35
134 INT303808 Positive_regulation of Gene_expression of Tdp1 1 0.69 9.07 0.35
135 INT275077 Protein_catabolism of Pde9a 1 0.01 0.05 0.35
136 INT275068 Negative_regulation of Protein_catabolism of Pde9a 1 0.01 0.05 0.35
137 INT235122 Negative_regulation of Positive_regulation of PDE2A 1 0.01 0.72 0.35
138 INT235113 Positive_regulation of Negative_regulation of PDE2A 1 0.01 0.72 0.35
139 INT135945 Positive_regulation of Positive_regulation of PDE2A 2 0.12 0.78 0.34
140 INT235849 Regulation of Transcription of Pde4a 1 0.01 0.15 0.33
141 INT303811 Binding of Tdp1 1 0.37 8.69 0.33
142 INT276012 Gene_expression of Pde1b 8 0.66 0.58 0.32
143 INT276027 Positive_regulation of Pde1b 7 0.59 0.71 0.32
144 INT182073 Binding of APEX1 4 0.12 1.72 0.32
145 INT219588 Negative_regulation of Gene_expression of Pde3a 1 0.25 0 0.32
146 INT219563 Gene_expression of Pde3a 1 0.39 0 0.32
147 INT81801 Negative_regulation of Samhd1 1 0.00 0.09 0.31
148 INT257213 Binding of PDE4A 5 0.36 1.69 0.3
149 INT275073 Positive_regulation of Negative_regulation of Pde5a 1 0.22 0.45 0.3
150 INT209140 Transcription of PDE4A 3 0.71 0.59 0.26
151 INT82579 Regulation of Gene_expression of PDE4B 1 0.45 0.15 0.25
152 INT82581 Regulation of PDE4B 1 0.45 0.15 0.25
153 INT273341 Transcription of Pde4d 2 0.54 0.68 0.24
154 INT273329 Regulation of Negative_regulation of Pde7a 1 0.38 0.68 0.24
155 INT243971 Phosphorylation of Plcl1 1 0.11 0.31 0.24
156 INT263124 Positive_regulation of Regulation of PDE4A 1 0.26 0.65 0.24
157 INT273336 Regulation of Negative_regulation of Pde4d 1 0.35 0.68 0.24
158 INT101300 Positive_regulation of Gene_expression of Samhd1 1 0.09 0.38 0.23
159 INT249115 Localization of Pde6b 6 0.68 1.09 0.21
160 INT79452 Transcription of PDE4B 1 0.52 0 0.21
161 INT273181 Negative_regulation of Localization of PDE4D 1 0.18 0.68 0.2
162 INT30069 Regulation of Pde3a 1 0.06 0 0.2
163 INT89772 Positive_regulation of APEX1 4 0.21 2.29 0.19
164 INT42375 Positive_regulation of Positive_regulation of Pde5a 2 0.14 0.1 0.19
165 INT101303 Positive_regulation of Samhd1 1 0.09 0.3 0.19
166 INT275543 Negative_regulation of Gene_expression of PDE4D 1 0.11 0.87 0.19
167 INT303812 Regulation of Tdp1 1 0.45 3.32 0.19
168 INT263128 Negative_regulation of Binding of PDE4A 3 0.22 1.33 0.18
169 INT188310 Binding of Pde4b 2 0.06 0.77 0.18
170 INT263126 Negative_regulation of Binding of PDE3A 1 0.13 0.62 0.18
171 INT42376 Regulation of Positive_regulation of Pde5a 1 0.03 0 0.18
172 INT163053 Regulation of Negative_regulation of Pde10a 1 0.45 0 0.18
173 INT98276 Regulation of PDE2A 2 0.07 1.54 0.17
174 INT343714 Negative_regulation of Positive_regulation of Pde6b 1 0.15 1.87 0.17
175 INT219576 Positive_regulation of Gene_expression of Pde3a 1 0.29 0 0.17
176 INT275082 Regulation of Pde9a 1 0.00 0.28 0.16
177 INT177528 Negative_regulation of Binding of Pde5a 1 0.34 0.46 0.15
178 INT273184 Localization of PDE4B 1 0.29 0.61 0.14
179 INT145044 Regulation of Plcl1 2 0.35 0.97 0.13
180 INT274166 Phosphorylation of Pde4a 1 0.30 1.1 0.13
181 INT219593 Regulation of Binding of Pde4d 1 0.44 0 0.13
182 INT79451 Positive_regulation of Transcription of PDE4B 1 0.45 0 0.13
183 INT275069 Negative_regulation of Gene_expression of Pde5a 1 0.26 0.54 0.13
184 INT84749 Gene_expression of PDE2A 3 0.73 0.84 0.12
185 INT182078 Gene_expression of APEX1 3 0.59 4.77 0.12
186 INT225448 Binding of Plcl1 3 0.13 0.28 0.12
187 INT135946 Positive_regulation of Gene_expression of PDE2A 1 0.12 0.77 0.12
188 INT263130 Phosphorylation of PDE4A 2 0.42 0.67 0.11
189 INT196773 Negative_regulation of Positive_regulation of Pde1a 1 0.01 0 0.11
190 INT243983 Localization of Plcl1 1 0.11 0.15 0.11
191 INT135944 Regulation of Regulation of PDE2A 1 0.07 0.73 0.1
192 INT219574 Phosphorylation of Pde4d 1 0.79 0.33 0.1
193 INT275587 Regulation of Negative_regulation of PDE4B 1 0.08 0.89 0.1
194 INT263134 Binding of PDE3A 1 0.15 0.47 0.09
195 INT303805 Positive_regulation of Phosphorylation of Tdp1 1 0.50 3.27 0.09
196 INT80630 Protein_catabolism of PDE2A 2 0.19 0.91 0.08
197 INT273349 Regulation of Gene_expression of Pde7a 1 0.38 0.32 0.08
198 INT303795 Negative_regulation of Tdp1 1 0.43 1.71 0.08
199 INT303806 Negative_regulation of Gene_expression of Tdp1 1 0.58 3.26 0.08
200 INT257205 Transcription of Pde5a 1 0.21 0 0.08
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox