GO:0008083

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Name growth factor activity
Categary Function
Go Slim No
Go Link GO:0008083
Unique Molecular Interactions 7071
Total Molecular Interactions 10236
Total Single Events 81214
Pain Genes Associated 224

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for growth factor activity. They are ordered first by their pain relevance and then by number of times they were reported for growth factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2
2 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
3 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
4 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
5 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21
6 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
7 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
8 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
9 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
10 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
11 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
12 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
13 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
14 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
15 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
16 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
17 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71
18 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
19 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
20 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
21 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
22 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
23 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
24 INT64756 oh Negative_regulation of Gpi1 1 0.03 0 4.09
25 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08
26 INT11248 Gh Positive_regulation of Ghrh 2 0.26 0.09 4.04
27 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
28 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
29 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
30 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
31 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
32 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
33 INT107331 Binding of PPBP and Adarb1 1 0.01 0 3.67
34 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
35 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
36 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
37 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
38 INT13729 GHRH Positive_regulation of Localization of GH1 13 0.62 0.59 3.2
39 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
40 INT17456 Binding of CSF2 and POMC 3 0.32 4.06 3.15
41 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
42 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
43 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
44 INT152699 Bdnf Positive_regulation of Ltp 5 0.05 1.22 2.95
45 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
46 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
47 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
48 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
49 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
50 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
51 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
52 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
53 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
54 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
55 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
56 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
57 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
58 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
59 INT87267 Binding of BMP8B and KRIT1 1 0.06 0.16 2.69
60 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
61 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
62 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62
63 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
64 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
65 INT340117 Binding of Bdnf and Pain1 1 0.01 2.48 2.55
66 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53
67 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
68 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
69 INT20411 Ghrh Positive_regulation of Gh1 6 0.56 0.62 2.47
70 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46
71 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
72 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
73 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
74 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37
75 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
76 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
77 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
78 INT108987 Ngf Regulation of Gene_expression of Sit1 1 0.00 1.46 2.32
79 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
80 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
81 INT350148 Binding of IL12A and ERAL1 1 0.21 8.23 2.26
82 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
83 INT7367 Ghrh Regulation of Localization of Gh1 5 0.49 1.55 2.25
84 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
85 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
86 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
87 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
88 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
89 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
90 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
91 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
92 INT9180 Ghrh Regulation of Localization of Gh 3 0.24 0.25 2.18
93 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
94 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
95 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
96 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
97 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
98 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
99 INT3576 Sst Negative_regulation of Localization of Gh1 6 0.23 0 2.13
100 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
101 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13
102 INT351380 Ngf Regulation of TPM1 1 0.44 2.17 2.11
103 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
104 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
105 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
106 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
107 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
108 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
109 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
110 INT26948 Pomc Positive_regulation of Localization of Gh1 2 0.22 0.15 1.99
111 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
112 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
113 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
114 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
115 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
116 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
117 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
118 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
119 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
120 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
121 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
122 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85
123 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
124 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
125 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
126 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
127 INT16891 GHRH Regulation of GH1 5 0.37 1.94 1.82
128 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
129 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
130 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79
131 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
132 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
133 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
134 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73
135 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
136 INT108129 GDNF Regulation of Gene_expression of GRHL3 1 0.21 0.39 1.71
137 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
138 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
139 INT80199 Ngf Regulation of Transcription of Rab38 1 0.01 1.48 1.68
140 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
141 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
142 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
143 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
144 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
145 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
146 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
147 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
148 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62
149 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
150 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
151 INT167200 Gtf3a Regulation of Gene_expression of Ngf 1 0.08 1.47 1.6
152 INT266768 NGF Positive_regulation of Localization of SFTPA1 1 0.01 1.65 1.6
153 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
154 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
155 INT40827 Sstr1 Negative_regulation of Localization of Gh1 1 0.13 0 1.58
156 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
157 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
158 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
159 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
160 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
161 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
162 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
163 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
164 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
165 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54
166 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
167 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
168 INT69031 IL12A Positive_regulation of IFNA1 9 0.13 4.23 1.52
169 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
170 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
171 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
172 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
173 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
174 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
175 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 0.03 1.28 1.49
176 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
177 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48
178 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
179 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
180 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
181 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
182 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
183 INT21536 Binding of Il2 and Il1 1 0.28 0 1.47
184 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
185 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
186 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
187 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
188 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
189 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44
190 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
191 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
192 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
193 INT158282 Binding of Penk and Csf2 1 0.33 0.87 1.44
194 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
195 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43
196 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
197 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
198 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
199 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
200 INT34834 Ghrh Positive_regulation of Gene_expression of Gh1 2 0.65 0 1.4

Single Events

The table below shows the top 100 pain related interactions that have been reported for growth factor activity. They are ordered first by their pain relevance and then by number of times they were reported in growth factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT876 Localization of Gh1 843 0.80 67.75 340.82
3 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1
4 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
5 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
6 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
7 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
8 INT1893 Localization of Gh 1041 0.79 340.23 256.58
9 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
10 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
11 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82
12 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
13 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71
14 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
15 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18
16 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23
17 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69
18 INT252 Localization of GH1 529 0.80 227.4 122.05
19 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
20 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68
21 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12
22 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01
23 INT1530 Regulation of Gh 382 0.61 115.96 112.47
24 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
25 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84
26 INT12082 Localization of IL6 365 0.81 241.78 105.78
27 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
28 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
29 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98
30 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89
31 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5
32 INT67682 Localization of Bdnf 204 0.81 72.36 88.92
33 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27
34 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97
35 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91
36 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12
37 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
38 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
39 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16
40 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
41 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
42 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
43 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96
44 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
45 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28
46 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71
47 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
48 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42
49 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92
50 INT3034 Localization of Ngf 126 0.81 50.81 72.84
51 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
52 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
53 INT6849 Localization of IL1B 229 0.81 112.56 69.63
54 INT19511 Localization of Il6 212 0.81 118.17 67.67
55 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73
56 INT11807 Gene_expression of Il2 266 0.78 112 64.97
57 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5
58 INT11937 Localization of Il6 228 0.81 139.83 64.39
59 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
60 INT10706 Regulation of Il6 150 0.62 93.23 62.34
61 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
62 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
63 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45
64 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03
65 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
66 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06
67 INT1782 Regulation of Gh1 125 0.62 22 55.74
68 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
69 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24
70 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
71 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96
72 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81
73 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77
74 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21
75 INT921 Regulation of GH1 172 0.60 52.88 51.04
76 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
77 INT9210 Regulation of IL6 166 0.62 125.61 49.95
78 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
79 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75
80 INT531 Gene_expression of GH1 376 0.75 193.45 46.24
81 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85
82 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
83 INT19078 Binding of Ngf 78 0.48 31.03 44.33
84 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56
85 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55
86 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5
87 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32
88 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
89 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97
90 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
91 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
92 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64
93 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
94 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
95 INT20210 Localization of Ngf 69 0.79 46.22 38.57
96 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77
97 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
98 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
99 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72
100 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3
101 INT6484 Binding of IL1B 122 0.47 75.84 35.07
102 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78
103 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67
104 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
105 INT10763 Localization of IL2 157 0.80 81.11 33.21
106 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07
107 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92
108 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
109 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
110 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39
111 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22
112 INT9655 Regulation of Il6 98 0.62 70.92 31.95
113 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7
114 INT9347 Localization of Il1b 58 0.81 26.13 31.53
115 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
116 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49
117 INT94388 Gene_expression of GDF15 124 0.77 79.48 31.42
118 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4
119 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16
120 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
121 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
122 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82
123 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77
124 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75
125 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11
126 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04
127 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96
128 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
129 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44
130 INT86437 Binding of IL6 154 0.48 121.22 29.3
131 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78
132 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5
133 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47
134 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
135 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99
136 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
137 INT14690 Localization of CSF2 124 0.80 85.17 27.26
138 INT47685 Positive_regulation of Positive_regulation of Bdnf 32 0.70 20.05 27.03
139 INT56053 Negative_regulation of Bdnf 77 0.58 64.4 26.83
140 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81
141 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
142 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
143 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14
144 INT20044 Negative_regulation of Gpi1 50 0.59 29.96 26
145 INT63769 Regulation of Ngf 44 0.62 21.82 25.84
146 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66
147 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
148 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
149 INT77793 Positive_regulation of Gdnf 54 0.70 23.76 25.08
150 INT48240 Binding of Ngf 46 0.46 23.51 24.42
151 INT96557 Binding of Bdnf 46 0.47 21.74 24.26
152 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
153 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
154 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
155 INT66026 Gene_expression of Cxcl1 74 0.78 31.87 23.37
156 INT50039 Positive_regulation of Il4 48 0.55 34.8 23.34
157 INT74423 Localization of IL10 91 0.80 61.6 22.95
158 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
159 INT113925 Localization of Bdnf 59 0.79 24.03 22.76
160 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
161 INT48081 Localization of Il1b 46 0.80 21.59 22.4
162 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38
163 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
164 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
165 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15
166 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
167 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63
168 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52
169 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
170 INT11157 Binding of EGF 88 0.48 53.73 21.25
171 INT30887 Negative_regulation of Ngf 56 0.59 32.96 20.86
172 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85
173 INT15796 Regulation of IL2 66 0.61 25.43 20.62
174 INT102203 Transcription of Bdnf 35 0.71 18.26 20.59
175 INT20379 Localization of Il4 85 0.73 51.22 20.55
176 INT51474 Binding of Il6 55 0.48 44.99 20.52
177 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48
178 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39
179 INT57257 Gene_expression of IL7 69 0.62 50.24 20.36
180 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
181 INT49985 Transcription of Il6 62 0.72 40.13 20.29
182 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
183 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
184 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03
185 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98
186 INT64261 Negative_regulation of Positive_regulation of Ngf 21 0.59 16.28 19.78
187 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
188 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93
189 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
190 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65
191 INT101988 Positive_regulation of GDF15 71 0.69 51.03 18.56
192 INT13454 Positive_regulation of Positive_regulation of Gh 49 0.68 14.53 18.49
193 INT103469 Positive_regulation of Gene_expression of BDNF 59 0.67 24.39 18.36
194 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
195 INT61626 Transcription of IL6 73 0.72 42.04 17.86
196 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
197 INT49922 Positive_regulation of Positive_regulation of Ngf 21 0.67 14.46 17.68
198 INT106556 Negative_regulation of Gene_expression of Bdnf 42 0.59 34.71 17.64
199 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
200 INT102903 Regulation of Gene_expression of Bdnf 35 0.62 20.1 17.42
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