GO:0008097

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Name 5S rRNA binding
Categary Function
Go Slim No
Go Link GO:0008097
Unique Molecular Interactions 63
Total Molecular Interactions 107
Total Single Events 757
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for 5S rRNA binding. They are ordered first by their pain relevance and then by number of times they were reported for 5S rRNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
2 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
3 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
4 INT27775 Binding of LH and Tst 1 0.25 0 0.93
5 INT343599 Gys1 Regulation of Tst 1 0.01 0 0.75
6 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
7 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
8 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
9 INT305732 Tst Positive_regulation of Creb1 1 0.12 0.33 0.57
10 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55
11 INT122838 Mdh1 Positive_regulation of Tst 1 0.78 0.4 0.55
12 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54
13 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
14 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
15 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
16 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
17 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
18 INT324819 Hmgb1 Positive_regulation of Gene_expression of Maob 1 0.09 0.44 0.37
19 INT324827 Hmgb1 Positive_regulation of Bad 1 0.02 0.43 0.36
20 INT352821 Tph2 Regulation of Tst 1 0.31 0.46 0.36
21 INT352822 SNRNP70 Regulation of Tst 1 0.34 0.46 0.36
22 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32
23 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 0.23 0.2 0.25
24 INT323610 Tlr4 Positive_regulation of Hmgb1 1 0.25 0.2 0.25
25 INT253765 Apex1 Positive_regulation of Hmgb1 1 0.09 1.27 0.24
26 INT343914 Hmgb1 Positive_regulation of Gene_expression of IL12A 1 0.01 0.41 0.24
27 INT253771 Gopc Positive_regulation of Hmgb1 1 0.03 1.27 0.24
28 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 0.05 0.41 0.24
29 INT317704 Binding of Gabrg1 and Tst 1 0.20 0.37 0.24
30 INT253773 TNF Positive_regulation of Hmgb1 1 0.09 1.21 0.23
31 INT344833 Binding of Ager and Hmgb1 1 0.08 0.72 0.22
32 INT258289 Hmgb1 Positive_regulation of Tlr2 4 0.48 3.61 0.19
33 INT324815 Binding of Hmgb1 and Caprin1 1 0.01 0.65 0.19
34 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
35 INT323613 Il1 Regulation of Localization of Hmgb1 1 0.10 0.75 0.19
36 INT215094 Il6 Positive_regulation of Hmgb1 1 0.18 1.84 0.17
37 INT344832 Hmgb1 Positive_regulation of Gene_expression of Nos2 1 0.12 0.82 0.17
38 INT343920 Binding of TLR4 and Hmgb1 1 0.39 0.97 0.13
39 INT324866 Hmgb1 Positive_regulation of Tlr4 1 0.16 1.29 0.13
40 INT343917 Binding of IRF6 and Hmgb1 1 0.05 0.98 0.13
41 INT254578 Binding of TNF and Tst 1 0.02 1.57 0.13
42 INT253761 Hmgb1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.73 0.12
43 INT253772 Binding of THBD and Hmgb1 1 0.05 0.95 0.12
44 INT253775 Negative_regulation of Binding of THBD and Hmgb1 1 0.06 0.69 0.12
45 INT215095 Negative_regulation of Il6 Positive_regulation of Hmgb1 1 0.13 1.03 0.09
46 INT250730 Hmgb1 Positive_regulation of Localization of TNF 1 0.08 0.92 0.09
47 INT258290 Hmgb1 Regulation of Positive_regulation of Tlr2 1 0.46 1.04 0.05
48 INT315803 Binding of FL and Tst 1 0.04 0.66 0.04
49 INT324859 Hmgb1 Positive_regulation of ecs 1 0.03 0.74 0.03
50 INT324798 Hmgb1 Positive_regulation of Positive_regulation of Mthfd1 1 0.04 0.16 0.03
51 INT324561 Hmgb1 Positive_regulation of Gene_expression of Arc 1 0.18 0.65 0
52 INT318081 Binding of RPL5 and UBC 1 0.02 0.52 0
53 INT253769 Binding of Hmgb1 and Il1 1 0.01 0.27 0
54 INT191577 Binding of Pde6b and Tst 1 0.02 0.48 0
55 INT318102 Binding of RPL5 and Ldha 1 0.08 0.66 0
56 INT318101 Binding of RPL5 and Ppia 1 0.07 0.52 0
57 INT315813 Binding of Tst and KRT20 1 0.10 0.35 0
58 INT324558 Hmgb1 Positive_regulation of Gene_expression of Kiss1 1 0.24 0.65 0
59 INT315814 Tst Positive_regulation of Localization of RTEL1 1 0.02 2.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for 5S rRNA binding. They are ordered first by their pain relevance and then by number of times they were reported in 5S rRNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
2 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
3 INT17451 Positive_regulation of Tst 23 0.67 8.85 9.52
4 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
5 INT3107 Regulation of Tst 11 0.54 4.83 7.85
6 INT119411 Negative_regulation of Tst 22 0.38 7.84 7.63
7 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
8 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
9 INT27774 Gene_expression of Tst 13 0.68 12.86 4.83
10 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15
11 INT215085 Positive_regulation of Gene_expression of Hmgb1 17 0.63 16.81 4.13
12 INT144702 Gene_expression of Tst 19 0.68 12.87 4.04
13 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4
14 INT101506 Regulation of Tst 13 0.48 7.34 3.94
15 INT28325 Negative_regulation of Tst 13 0.51 12.41 3.16
16 INT163582 Positive_regulation of Tst 10 0.43 2.73 2.5
17 INT253755 Regulation of Hmgb1 7 0.55 6.23 1.8
18 INT160105 Binding of Tst 6 0.31 1.23 1.56
19 INT215077 Negative_regulation of Positive_regulation of Hmgb1 3 0.42 5.09 1.05
20 INT215078 Negative_regulation of Gene_expression of Hmgb1 4 0.41 4.3 0.96
21 INT122834 Negative_regulation of Positive_regulation of Tst 2 0.38 0.46 0.79
22 INT3108 Binding of Tst 11 0.32 13.37 0.77
23 INT190522 Regulation of Gene_expression of Hmgb1 1 0.39 1.47 0.77
24 INT315800 Localization of Tst 11 0.54 8.09 0.73
25 INT145142 Gene_expression of RPL5 3 0.12 1.54 0.62
26 INT157227 Localization of Tst 9 0.74 6.78 0.58
27 INT215070 Regulation of Localization of Hmgb1 4 0.26 2.23 0.49
28 INT150258 Positive_regulation of Gene_expression of Tst 2 0.34 3.54 0.45
29 INT352592 Positive_regulation of Negative_regulation of Hmgb1 1 0.44 1.31 0.42
30 INT317686 Negative_regulation of Localization of Tst 1 0.30 0.79 0.36
31 INT258283 Positive_regulation of Positive_regulation of Hmgb1 3 0.44 3.1 0.3
32 INT331591 Transcription of Hmgb1 1 0.28 0.92 0.3
33 INT317685 Positive_regulation of Positive_regulation of Tst 1 0.31 0.09 0.25
34 INT272231 Regulation of Localization of Tst 1 0.05 1.17 0.24
35 INT139526 Positive_regulation of Positive_regulation of Tst 1 0.41 0.13 0.21
36 INT315801 Regulation of Gene_expression of Tst 2 0.29 0.79 0.15
37 INT258272 Negative_regulation of Binding of Hmgb1 1 0.53 1.82 0.15
38 INT344828 Protein_catabolism of Hmgb1 1 0.48 0.67 0.14
39 INT344810 Positive_regulation of Protein_catabolism of Hmgb1 1 0.27 0.67 0.14
40 INT306408 Regulation of Gene_expression of Tst 1 0.05 1.69 0.11
41 INT318343 Regulation of Binding of Hmgb1 1 0.11 0.41 0.1
42 INT309010 Transcription of Tst 1 0.33 0.41 0
43 INT309009 Negative_regulation of Binding of Tst 1 0.20 1.5 0
44 INT165077 Positive_regulation of Localization of Tst 1 0.39 0 0
45 INT315796 Positive_regulation of Gene_expression of Tst 1 0.32 5 0
46 INT315802 Positive_regulation of Localization of Tst 1 0.32 1.83 0
47 INT352813 Phosphorylation of Tst 1 0.55 0.49 0
48 INT258279 Positive_regulation of Binding of Hmgb1 1 0.45 0.26 0
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