GO:0008123

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Name cholesterol 7-alpha-monooxygenase activity
Categary Function
Go Slim No
Go Link GO:0008123
Unique Molecular Interactions 14
Total Molecular Interactions 16
Total Single Events 95
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cholesterol 7-alpha-monooxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported for cholesterol 7-alpha-monooxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT262155 Nr5a2 Positive_regulation of Cyp7a1 1 0.07 0.24 0.45
2 INT262186 Nr0b2 Positive_regulation of Negative_regulation of Cyp7a1 1 0.12 0.28 0.4
3 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36
4 INT335015 Fgf15 Negative_regulation of Gene_expression of Cyp7a1 1 0.57 0.2 0.24
5 INT262211 Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23
6 INT262159 Positive_regulation of Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23
7 INT229289 FGF19 Negative_regulation of CYP7A1 1 0.26 0.32 0.16
8 INT173121 PPARA Negative_regulation of Gene_expression of CYP7A1 1 0.18 0.48 0.12

Single Events

The table below shows the top 100 pain related interactions that have been reported for cholesterol 7-alpha-monooxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported in cholesterol 7-alpha-monooxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT176205 Gene_expression of Cyp7a1 8 0.69 2.5 2.45
2 INT262117 Negative_regulation of Gene_expression of Cyp7a1 3 0.25 0.91 1.6
3 INT334977 Regulation of Gene_expression of Cyp7a1 2 0.40 0.43 0.94
4 INT197010 Positive_regulation of CYP7A1 4 0.47 1.75 0.7
5 INT229326 Negative_regulation of CYP7A1 3 0.29 1.03 0.7
6 INT262093 Positive_regulation of Gene_expression of Cyp7a1 2 0.44 0.81 0.55
7 INT329888 Positive_regulation of Transcription of CYP7A1 1 0.20 0.9 0.46
8 INT229307 Positive_regulation of Negative_regulation of CYP7A1 1 0.31 0.1 0.43
9 INT176186 Negative_regulation of Cyp7a1 5 0.46 2.07 0.39
10 INT176170 Regulation of Cyp7a1 2 0.21 0.5 0.32
11 INT335088 Regulation of Regulation of Cyp7a1 1 0.19 0.1 0.32
12 INT176200 Positive_regulation of Cyp7a1 2 0.37 0.4 0.31
13 INT329886 Transcription of CYP7A1 1 0.28 0.45 0.23
14 INT173171 Gene_expression of CYP7A1 2 0.45 1.02 0.14
15 INT173188 Regulation of Gene_expression of CYP7A1 1 0.22 0.48 0.12
16 INT229319 Regulation of Positive_regulation of CYP7A1 1 0.30 0.42 0.08
17 INT229325 Positive_regulation of Gene_expression of CYP7A1 1 0.34 0.6 0.05
18 INT345480 Binding of CYP7A1 1 0.29 0 0.03
19 INT176172 Transcription of Cyp7a1 1 0.57 1.04 0
20 INT176179 Negative_regulation of Positive_regulation of Cyp7a1 1 0.34 0.4 0
21 INT187419 Regulation of CYP7A1 1 0.05 0.23 0
22 INT176215 Regulation of Transcription of Cyp7a1 1 0.49 0.79 0
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