GO:0008152

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Name metabolic process
Categary Process
Go Slim No
Go Link GO:0008152
Unique Molecular Interactions 2545
Total Molecular Interactions 3266
Total Single Events 27988
Pain Genes Associated 362

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT64756 oh Negative_regulation of Gpi1 1 0.03 0 4.09
3 INT107801 Ugt1a5 Positive_regulation of Localization of Prl 3 0.76 1 3.9
4 INT215943 Binding of Mmp14 and Timp2 1 0.21 1.59 3.33
5 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
6 INT91350 Binding of Pla2g4a and RYBP 1 0.00 1.15 2.65
7 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
8 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
9 INT14687 Binding of Penk and Ppt1 1 0.41 0 2.46
10 INT231968 Binding of Cpn1 and Rvm 1 0.11 1.57 2.45
11 INT231970 Binding of Cpn1 and Pag1 1 0.07 1.56 2.44
12 INT247601 Binding of PEPD and SCN9A 1 0.15 2.26 2.27
13 INT231971 Binding of Cpn1 and Shbdp1 1 0.04 1.39 2.26
14 INT231967 Binding of Psmd1 and Cpn1 1 0.06 1.39 2.25
15 INT231969 Binding of Cfp and Cpn1 1 0.05 1.38 2.25
16 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
17 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
18 INT213973 Binding of Pax3 and Mthfd1 1 0.00 0.16 1.99
19 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
20 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
21 INT243043 Binding of Mmp9 and Timp1 1 0.05 0.25 1.86
22 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
23 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
24 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
25 INT167320 Binding of CPE and OPRM1 1 0.14 0.63 1.77
26 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
27 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
28 INT61049 Binding of Oprd1 and Negative_regulation of Gene_expression of Odc1 1 0.21 0 1.64
29 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
30 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
31 INT109739 Binding of ITPA and Pcyt1b 1 0.16 0.72 1.6
32 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
33 INT237286 Dlat Regulation of Prep 1 0.01 0 1.57
34 INT168611 Binding of Mmp9 and Ndor1 1 0.29 0.41 1.57
35 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
36 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55
37 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54
38 INT317538 Binding of Neu3 and Mors1 1 0.00 0 1.51
39 INT166676 Binding of PRKCA and UGT1A6 1 0.30 0 1.5
40 INT123899 Binding of CYP3A4 and UGT2B7 1 0.52 0 1.46
41 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
42 INT172203 Binding of Comt and Maoa 1 0.31 0.98 1.43
43 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42
44 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
45 INT29554 Ebp Positive_regulation of LH 2 0.40 0.12 1.41
46 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
47 INT167528 Ppt1 Negative_regulation of Gene_expression of Tac4 1 0.06 0.49 1.39
48 INT116827 Binding of UCHL1 and TRPV1 1 0.41 0.88 1.39
49 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 0.26 0.49 1.38
50 INT168865 Cd38 Regulation of Wdtc1 1 0.03 0.12 1.35
51 INT115272 Neu1 Positive_regulation of Coq10a 1 0.43 0.41 1.35
52 INT115271 Neu1 Positive_regulation of Coq10a 1 0.01 0.41 1.35
53 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
54 INT2641 Binding of Pomc and Lct 2 0.31 0.57 1.32
55 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
56 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3
57 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29
58 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
59 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
60 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28
61 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
62 INT195541 Lct Positive_regulation of Gene_expression of Grm2 1 0.02 0.4 1.27
63 INT70226 Binding of TAC1 and B3GAT1 4 0.24 4.5 1.26
64 INT124099 Binding of GGT5 and RYBP 1 0.00 0.34 1.26
65 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
66 INT132465 Ltf Positive_regulation of Nos1 1 0.35 0.05 1.24
67 INT202039 CAMK2N2 Negative_regulation of MMP1 1 0.00 0.73 1.24
68 INT64758 Negative_regulation of oh Negative_regulation of Gpi1 1 0.03 0 1.24
69 INT202036 CAMK2N2 Negative_regulation of MMP3 1 0.00 0.73 1.24
70 INT202040 CAMK2N2 Negative_regulation of MMP7 1 0.00 0.73 1.24
71 INT168459 Sult1a1 Negative_regulation of Gene_expression of Arr3 1 0.05 2.98 1.23
72 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
73 INT187174 RPS3AP9 Negative_regulation of MMP2 1 0.00 0.9 1.22
74 INT96261 Positive_regulation of Pik3cd Positive_regulation of Plcg2 1 0.02 0 1.21
75 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2
76 INT264333 IL-17 Positive_regulation of Gene_expression of Mmp1a 1 0.05 2.88 1.18
77 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
78 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
79 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
80 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
81 INT68160 Alox5 Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.13
82 INT68156 Pla2g1b Positive_regulation of Positive_regulation of Alox5 1 0.03 0.64 1.13
83 INT68158 Pla2g1b Positive_regulation of Pdpk1 1 0.05 0.63 1.12
84 INT68159 Pla2g1b Positive_regulation of Positive_regulation of Pdpk1 1 0.05 0.64 1.12
85 INT68161 Mthfs Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.12
86 INT68155 Pla2g1b Positive_regulation of Positive_regulation of Mthfs 1 0.03 0.64 1.12
87 INT168303 Binding of SNRPB and UGT2B7 1 0.20 0 1.09
88 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08
89 INT187176 Binding of BSG and MMP1 1 0.09 1.18 1.08
90 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
91 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
92 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
93 INT145906 Elane Regulation of Transcription of Oprm1 1 0.10 0.14 1.04
94 INT349576 Binding of Ugt2b and Sult1a1 1 0.00 0.45 1.03
95 INT144069 Positive_regulation of TRPV1 Positive_regulation of Gene_expression of MMP1 1 0.43 1.35 1.03
96 INT132464 Ltf Negative_regulation of Positive_regulation of Nos1 1 0.33 0 1.03
97 INT98555 Oprm1 Positive_regulation of Casp8 1 0.51 0.36 1.02
98 INT12138 Ins1 Negative_regulation of Chat 1 0.27 0.71 1.01
99 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
100 INT71000 Positive_regulation of Adarb1 Positive_regulation of Odc1 1 0.01 0 1
101 INT154237 Binding of CYP2D6 and Ugt2b7 1 0.41 0.75 1
102 INT154236 Binding of TBX3 and Ugt2b7 1 0.41 0.74 1
103 INT76150 Das Negative_regulation of Gpi1 1 0.03 0 0.99
104 INT317584 Binding of Lbp and Pgp 1 0.24 1.08 0.99
105 INT238091 Binding of GRIP1 and Mmp24 1 0.00 0 0.98
106 INT56742 LIF Positive_regulation of Chat 1 0.02 0.2 0.98
107 INT238092 Binding of SHBG and Mmp24 1 0.04 0 0.98
108 INT90385 EXTL3 Regulation of Ctsl 1 0.00 1.1 0.98
109 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97
110 INT195219 Binding of CPB2 and CSRP1 1 0.03 0.99 0.96
111 INT93234 Negative_regulation of Pde4b Negative_regulation of Gene_expression of Fos 1 0.41 0.1 0.96
112 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
113 INT351311 Has1 Regulation of Gene_expression of MMP3 1 0.11 1.15 0.95
114 INT266659 Binding of MMP9 and MOCS1 1 0.01 1.71 0.94
115 INT317559 Binding of Hint1 and Pla2g4a 1 0.01 0.06 0.94
116 INT144282 ACP1 Negative_regulation of Positive_regulation of PHOSPHO2 1 0.05 0.58 0.94
117 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93
118 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
119 INT144284 ACP1 Negative_regulation of PHOSPHO2 1 0.05 0.58 0.93
120 INT103933 Cps1 Negative_regulation of Gene_expression of Cd69 1 0.03 0.25 0.93
121 INT70802 Ngf Regulation of Ppt1 1 0.21 0.39 0.93
122 INT103930 Cps1 Negative_regulation of Gene_expression of Il2ra 1 0.02 0.25 0.93
123 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
124 INT96260 Pik3cd Regulation of Plcg2 1 0.02 0 0.92
125 INT243044 Mmp8 Regulation of Mmp9 1 0.05 1.45 0.91
126 INT48341 Negative_regulation of Pde8a Regulation of Ahsg 1 0.22 0 0.9
127 INT48342 Pde8a Regulation of Ahsg 1 0.24 0 0.9
128 INT111924 Cpb2 Negative_regulation of Positive_regulation of Plg 1 0.02 1.29 0.9
129 INT121700 IL12RB1 Positive_regulation of Gene_expression of MMP1 1 0.06 0.22 0.9
130 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
131 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 0.06 0.2 0.9
132 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9
133 INT108647 Binding of Grin2a and Camk1d 1 0.33 0.78 0.9
134 INT56779 Pomc Negative_regulation of Gene_expression of Odc1 2 0.31 0 0.89
135 INT121701 HRAS Negative_regulation of MMP1 1 0.06 0.2 0.89
136 INT121704 HRAS Negative_regulation of MMP3 1 0.06 0.19 0.89
137 INT218062 Abat Negative_regulation of Ctse 1 0.03 0.25 0.89
138 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
139 INT199189 Binding of Aldh2 and Ros1 1 0.06 0.3 0.88
140 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 0.06 0.19 0.88
141 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
142 INT57746 Il1 Regulation of Gene_expression of Ltc4s 1 0.36 0.33 0.88
143 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
144 INT272039 Ddc Positive_regulation of Gene_expression of Aanat 1 0.00 0.26 0.87
145 INT221257 Pde5a Positive_regulation of PRKG1 3 0.07 0.19 0.86
146 INT136540 Binding of CYP2C9 and Ugt1a6a 1 0.27 0.81 0.86
147 INT104126 STAT3 Regulation of Phospho1 1 0.00 0.06 0.86
148 INT196523 Binding of MMP2 and TIMP1 3 0.43 1.94 0.85
149 INT194856 Positive_regulation of Adora2b Negative_regulation of Positive_regulation of Mmp13 1 0.01 0.73 0.85
150 INT190165 MMP12 Positive_regulation of MMP2 1 0.13 0.72 0.85
151 INT270218 P2rx3 Positive_regulation of Pla2g4a 1 0.34 0.63 0.85
152 INT154439 Ufm1 Positive_regulation of Gene_expression of Abcb1a 1 0.00 0 0.85
153 INT25239 Ugt1a2 Positive_regulation of Ugt2b 1 0.30 0 0.85
154 INT260894 CRH Regulation of Localization of MMP3 1 0.21 0.36 0.85
155 INT251706 Chat Regulation of Gene_expression of Acot1 1 0.06 1.64 0.85
156 INT251708 Chat Regulation of Acot1 1 0.03 1.64 0.84
157 INT227156 UGT2B7 Regulation of Gene_expression of Gpm6a 1 0.01 0 0.84
158 INT12142 Ins1 Regulation of Chat 1 0.24 0.69 0.84
159 INT110236 Hk1 Regulation of CSAD 1 0.01 1.57 0.84
160 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 0.32 1.26 0.84
161 INT340115 Comt Regulation of Localization of Dusp1 1 0.12 0.83 0.83
162 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83
163 INT84087 B3GAT1 Positive_regulation of Localization of SST 1 0.06 0 0.83
164 INT106808 RECK Negative_regulation of MMP2 1 0.40 0.5 0.83
165 INT84102 B3GAT1 Positive_regulation of Localization of Glp1r 1 0.09 0 0.83
166 INT309001 Ins1 Positive_regulation of Mmp9 1 0.20 1.96 0.83
167 INT340114 Comt Regulation of Localization of Pain1 1 0.02 0.83 0.83
168 INT19299 ANG Regulation of AVP 1 0.25 0 0.82
169 INT63594 Snai1 Negative_regulation of Binding of Ugt1a2 1 0.05 0.32 0.82
170 INT340113 Comt Regulation of Bdnf 1 0.21 0.74 0.82
171 INT61052 Binding of Adarb1 and Negative_regulation of Gene_expression of Odc1 1 0.02 0 0.81
172 INT110726 Binding of ALB and LTF 1 0.01 0 0.81
173 INT213972 Calca Regulation of Mthfd1 1 0.05 0.19 0.8
174 INT141605 Gene_expression of Ctsl Positive_regulation of Positive_regulation of MET 1 0.34 0 0.8
175 INT190182 JUN Positive_regulation of MMP12 1 0.34 0.08 0.8
176 INT168455 Sult1a1 Negative_regulation of Nos2 1 0.08 1.99 0.79
177 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78
178 INT77526 Oprd1 Regulation of Positive_regulation of Odc1 1 0.01 0.12 0.78
179 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
180 INT168457 Sult1a1 Positive_regulation of Cat 1 0.15 1.56 0.78
181 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
182 INT107596 Binding of PPA1 and OPLL 1 0.00 1.13 0.77
183 INT104749 Ugt1a1 Regulation of Positive_regulation of G2e3 1 0.00 0.07 0.77
184 INT34241 Dlst Positive_regulation of Positive_regulation of LH 1 0.28 0 0.77
185 INT305034 Adcy8 Regulation of Localization of Adcy1 1 0.35 1.51 0.77
186 INT305033 Adcy1 Regulation of Localization of Adcy8 1 0.35 1.51 0.77
187 INT104748 Ugt1a1 Regulation of Positive_regulation of LOC100359830 1 0.01 0.07 0.77
188 INT190788 Adcy8 Positive_regulation of Adcy1 1 0.23 0.77 0.77
189 INT97863 Binding of NOS1 and GRHPR 1 0.05 0.23 0.77
190 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
191 INT231390 Pla2g4a Regulation of Pla2g2a 1 0.08 0.92 0.77
192 INT231388 Pla2g4a Regulation of Pla2g6 1 0.08 0.92 0.77
193 INT79532 Crh Regulation of Ugt1a10 1 0.00 0 0.76
194 INT107602 Binding of OPLL and Enpp1 1 0.15 1.12 0.76
195 INT46246 Tpsg1 Regulation of Ache 1 0.15 0.06 0.76
196 INT46247 Tpsg1 Regulation of Binding of Ache 1 0.15 0.06 0.76
197 INT155220 ABCG2 Positive_regulation of Abcc2 1 0.23 0.54 0.76
198 INT166672 YY1 Regulation of Binding of UGT1A6 1 0.48 0 0.76
199 INT155096 Stat3 Regulation of Mapk3 1 0.36 0.45 0.76
200 INT257222 Binding of Ltp and Pde5a 2 0.07 0.14 0.75

Single Events

The table below shows the top 100 pain related interactions that have been reported for metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
2 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72
3 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01
4 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9
5 INT20492 Gene_expression of MMP12 89 0.76 81.36 46.12
6 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02
7 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78
8 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
9 INT30169 Negative_regulation of Pde4a 107 0.58 81 36.23
10 INT99610 Localization of MMP9 126 0.79 48.46 32.67
11 INT2499 Positive_regulation of Sult1b1 51 0.43 2.83 32.38
12 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
13 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
14 INT2671 Positive_regulation of Odc1 82 0.70 11.03 29
15 INT116737 Localization of Mif 63 0.81 52.97 28.11
16 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71
17 INT14575 Positive_regulation of Ppt1 60 0.70 9.97 27.4
18 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03
19 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98
20 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
21 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13
22 INT20044 Negative_regulation of Gpi1 50 0.59 29.96 26
23 INT140193 Gene_expression of Mmp3 58 0.71 49.65 25.4
24 INT1728 Negative_regulation of Cndp2 36 0.57 3.76 25.39
25 INT93717 Gene_expression of Mmp3 85 0.78 33.95 24.89
26 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
27 INT67585 Gene_expression of UGT2B7 52 0.78 2.33 24.13
28 INT34487 Localization of MMP2 56 0.81 31.41 23.61
29 INT11829 Negative_regulation of Odc1 54 0.59 7.03 23.03
30 INT90300 Gene_expression of Abcb1a 56 0.78 11.05 22.89
31 INT4890 Gene_expression of Ppt1 51 0.77 8.93 21.83
32 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
33 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72
34 INT170313 Gene_expression of Mmp1a 50 0.65 38.53 21.36
35 INT4894 Transcription of Ppt1 34 0.67 5.93 21.06
36 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
37 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
38 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18
39 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86
40 INT113399 Positive_regulation of Pla2g4a 36 0.67 33.83 18.78
41 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35
42 INT187513 Positive_regulation of Pla2g4a 5 0.62 34.09 18.22
43 INT1060 Negative_regulation of Pla2g1b 50 0.57 22.91 18.12
44 INT23635 Positive_regulation of MMP12 31 0.59 28.19 17.95
45 INT7258 Localization of Sult1b1 42 0.68 0.17 17.85
46 INT73362 Negative_regulation of Abcb1a 46 0.59 8.78 17.81
47 INT81884 Gene_expression of Naa15 16 0.50 5.47 17.77
48 INT132997 Localization of Mmp9 59 0.80 45.9 17.61
49 INT101140 Negative_regulation of Tap1 7 0.50 9.08 17.46
50 INT195831 Phosphorylation of Pla2g4a 15 0.74 34.43 17.14
51 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1
52 INT49379 Localization of MMP12 26 0.77 13.07 16.93
53 INT32648 Gene_expression of Tyrp1 80 0.66 17.9 16.59
54 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4
55 INT99898 Gene_expression of Mmp14 37 0.56 28.54 16.39
56 INT209 Positive_regulation of Pde5a 30 0.21 2.54 16.31
57 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17
58 INT8571 Gene_expression of B3GAT1 54 0.75 36.85 15.98
59 INT6381 Negative_regulation of Chat 51 0.59 19.68 15.86
60 INT13400 Negative_regulation of Enpep 30 0.50 4.23 15.86
61 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
62 INT83682 Positive_regulation of Abcb1a 22 0.68 3.3 15.6
63 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
64 INT81486 Localization of MMP3 31 0.81 12.94 15.21
65 INT26501 Positive_regulation of Gene_expression of MMP2 51 0.67 39 15.16
66 INT103210 Localization of MMP1 43 0.78 12.15 15.13
67 INT4851 Positive_regulation of Chat 53 0.70 9.21 15.11
68 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07
69 INT12891 Negative_regulation of MMP3 41 0.58 17.99 15.06
70 INT16266 Gene_expression of Chat 80 0.67 16.14 15.01
71 INT11945 Regulation of Chat 38 0.62 7.75 14.97
72 INT7776 Gene_expression of Abcb1b 63 0.75 21.35 14.92
73 INT74587 Gene_expression of MMP8 31 0.78 24.4 14.91
74 INT1284 Negative_regulation of Mmp13 20 0.57 36.21 14.91
75 INT8794 Negative_regulation of Ppt1 35 0.57 6.44 14.52
76 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31
77 INT28510 Positive_regulation of Gpi 21 0.68 6.75 14.27
78 INT4736 Gene_expression of Chat 67 0.77 17.15 14.24
79 INT37430 Gene_expression of Gpi1 61 0.63 54.63 13.87
80 INT21937 Positive_regulation of Scly 16 0.39 22.34 13.76
81 INT111529 Phosphorylation of Mapk3 41 0.80 21.14 13.72
82 INT94051 Positive_regulation of Arg1 41 0.60 36.22 13.72
83 INT3112 Regulation of Odc1 39 0.62 4.73 13.69
84 INT190204 Positive_regulation of Gene_expression of MMP12 22 0.67 31.31 13.69
85 INT15011 Positive_regulation of Gpi1 29 0.47 12.47 13.48
86 INT95427 Positive_regulation of Mmp3 39 0.70 15.28 13.36
87 INT95726 Positive_regulation of Gene_expression of Naa15 1 0.45 1.43 13.33
88 INT59665 Positive_regulation of Ugt1a6 24 0.69 7.24 13.25
89 INT101147 Gene_expression of Uchl1 31 0.76 14.73 13.22
90 INT101119 Negative_regulation of Comt 19 0.58 8.77 13.09
91 INT10585 Localization of NAGLU 53 0.80 23.32 12.75
92 INT11897 Gene_expression of Atp7b 25 0.13 7.85 12.5
93 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45
94 INT13287 Gene_expression of Cpb2 27 0.56 7.84 11.95
95 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
96 INT72949 Binding of Mif 31 0.46 23.12 11.65
97 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64
98 INT148639 Gene_expression of Uchl1 30 0.59 16.76 11.54
99 INT3597 Positive_regulation of Pla2g1b 37 0.63 17.94 11.41
100 INT270238 Localization of Pla2g4a 1 0.72 17.99 11.35
101 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28
102 INT7350 Negative_regulation of Anpep 30 0.59 2.89 11.28
103 INT18334 Positive_regulation of Cpb2 24 0.69 2.98 11.22
104 INT17826 Positive_regulation of Pla2g1b 39 0.70 11.35 10.97
105 INT2496 Gene_expression of Sult1b1 32 0.66 3 10.97
106 INT85631 Positive_regulation of Tyrp1 40 0.64 18.73 10.84
107 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8
108 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76
109 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
110 INT34485 Negative_regulation of Localization of MMP2 17 0.50 9.96 10.49
111 INT6574 Negative_regulation of Pla2g1b 35 0.59 11.4 10.44
112 INT149015 Gene_expression of Tph2 20 0.78 9.45 10.4
113 INT87451 Positive_regulation of Mapk3 34 0.67 12.82 10.38
114 INT89282 Regulation of MMP9 39 0.60 25.45 10.34
115 INT58449 Binding of Mthfd1 47 0.47 22.02 10.29
116 INT95207 Negative_regulation of Pde5a 46 0.58 32.01 10.14
117 INT119777 Negative_regulation of Naalad2 9 0.40 5.93 10.11
118 INT32344 Localization of LTF 30 0.80 15.28 10.09
119 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08
120 INT86813 Gene_expression of Pla2g4a 26 0.75 42.31 10.07
121 INT107606 Negative_regulation of MMP1 38 0.42 11.94 10.01
122 INT113605 Negative_regulation of Gene_expression of Mmp9 25 0.41 22.92 9.98
123 INT95632 Positive_regulation of MMP8 26 0.70 10.06 9.96
124 INT29740 Gene_expression of ANG 55 0.78 24.53 9.86
125 INT55038 Gene_expression of Adcy8 10 0.77 28.79 9.8
126 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79
127 INT106510 Gene_expression of Ptges 70 0.75 36.18 9.75
128 INT140191 Positive_regulation of Gene_expression of Mmp13 25 0.67 13.47 9.71
129 INT102987 Regulation of MMP3 23 0.60 9.35 9.54
130 INT46054 Gene_expression of Decr1 39 0.65 12.82 9.48
131 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42
132 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37
133 INT47301 Gene_expression of Ctsl 27 0.76 7.72 9.32
134 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25
135 INT48233 Negative_regulation of Gene_expression of MMP1 34 0.58 12.94 9.08
136 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98
137 INT97649 Gene_expression of Dlat 48 0.66 13.77 8.94
138 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93
139 INT38173 Gene_expression of Ang 40 0.75 32.63 8.86
140 INT49205 Positive_regulation of B3GAT1 20 0.67 10.28 8.71
141 INT2500 Negative_regulation of Positive_regulation of Sult1b1 13 0.18 0.6 8.6
142 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54
143 INT105777 Gene_expression of Pde4a 30 0.76 12.67 8.52
144 INT109005 Gene_expression of Proc 61 0.75 37.86 8.49
145 INT15308 Localization of Chat 29 0.81 2.35 8.47
146 INT24651 Positive_regulation of Transcription of Ppt1 12 0.47 2.88 8.42
147 INT112711 Gene_expression of Phospho1 11 0.21 5.65 8.34
148 INT4021 Positive_regulation of PLA2G1B 35 0.70 23.27 8.2
149 INT88919 Positive_regulation of Casp9 39 0.70 28.64 8.18
150 INT18185 Gene_expression of Tyr 32 0.76 12.52 8.17
151 INT116996 Regulation of Pgp 9 0.51 7.51 8.01
152 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
153 INT2271 Gene_expression of F2 51 0.76 30.21 7.97
154 INT160168 Gene_expression of Pde10a 10 0.74 8.66 7.94
155 INT113671 Negative_regulation of Mmp3 26 0.49 6.33 7.88
156 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79
157 INT44537 Positive_regulation of Comt 7 0.69 2.62 7.78
158 INT23472 Binding of St8sia2 18 0.42 1.73 7.74
159 INT162393 Gene_expression of SMUG1 58 0.75 38.78 7.7
160 INT139493 Gene_expression of Scly 11 0.57 16.96 7.61
161 INT4022 Negative_regulation of PLA2G1B 30 0.59 10.41 7.58
162 INT74629 Gene_expression of Mmp7 17 0.55 12.78 7.58
163 INT159946 Gene_expression of Mat1a 23 0.77 15.33 7.49
164 INT70252 Gene_expression of Ugt1a6 20 0.77 3.89 7.45
165 INT89309 Negative_regulation of Pde4b 21 0.53 12.81 7.32
166 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25
167 INT47994 Negative_regulation of Lipg 45 0.50 27.19 7.24
168 INT101121 Regulation of Comt 19 0.53 10.66 7.22
169 INT80981 Regulation of Abcb1a 19 0.62 1.86 7.2
170 INT43727 Negative_regulation of Gene_expression of MMP3 16 0.40 4.81 7.18
171 INT111398 Localization of Mmp2 37 0.76 23.78 7.17
172 INT800 Negative_regulation of Grhpr 21 0.42 10.3 7.17
173 INT78199 Gene_expression of Neu1 65 0.75 62.88 7.16
174 INT2501 Positive_regulation of Positive_regulation of Sult1b1 19 0.19 2.38 7.16
175 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11
176 INT21938 Positive_regulation of Atp7b 26 0.10 11.33 7.1
177 INT5774 Regulation of Ppt1 22 0.60 4.97 7.1
178 INT50990 Regulation of Cpb2 12 0.37 2.71 7.07
179 INT58625 Gene_expression of Ugt2b1 19 0.77 1.95 7.05
180 INT168381 Positive_regulation of Mmp3 24 0.58 19.12 7.03
181 INT76120 Gene_expression of Ptprc 102 0.59 30.42 7.02
182 INT1973 Positive_regulation of NAGLU 36 0.65 14.78 7
183 INT717 Regulation of F2 29 0.61 17.46 6.99
184 INT168600 Binding of Mmp9 14 0.44 12.79 6.92
185 INT15012 Regulation of Gpi1 18 0.60 11.64 6.91
186 INT18778 Gene_expression of Ugt1a2 17 0.35 9.91 6.87
187 INT67568 Positive_regulation of Localization of MMP2 14 0.31 8.58 6.79
188 INT73642 Positive_regulation of Ctse 12 0.44 5.57 6.79
189 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75
190 INT24907 Gene_expression of PAPPA 42 0.75 28.32 6.63
191 INT11150 Positive_regulation of Dlst 31 0.51 9.01 6.63
192 INT29845 Positive_regulation of Sds 11 0.62 3.69 6.63
193 INT231964 Binding of Cpn1 1 0.25 5.28 6.63
194 INT7873 Positive_regulation of Ugt2b 36 0.70 0.72 6.59
195 INT133889 Gene_expression of Adamts1 78 0.76 48.05 6.58
196 INT517 Regulation of Mif 16 0.62 5.43 6.55
197 INT81886 Negative_regulation of Gene_expression of Naa15 3 0.38 1.73 6.48
198 INT38807 Negative_regulation of PLA2G6 29 0.59 10.1 6.42
199 INT150825 Binding of Comt 13 0.42 6.65 6.42
200 INT21613 Gene_expression of Pla2g1b 25 0.68 9.05 6.39
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