GO:0008156

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Name negative regulation of DNA replication
Categary Process
Go Slim No
Go Link GO:0008156
Unique Molecular Interactions 623
Total Molecular Interactions 781
Total Single Events 5394
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of DNA replication. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of DNA replication. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18
3 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
4 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
5 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
6 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
7 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65
8 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64
9 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
10 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
11 INT21425 Binding of Pomc and Gtpbp4 1 0.01 0.1 1.45
12 INT21424 Binding of Penk and Gtpbp4 1 0.02 0.16 1.2
13 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
14 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
15 INT64259 Binding of Gtpbp4 and Ptprg 1 0.06 0 1.1
16 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
17 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
18 INT130607 Hcrt Positive_regulation of H1 1 0.59 0.39 1.02
19 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99
20 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
21 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
22 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
23 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
24 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
25 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
26 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
27 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
28 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
29 INT207439 Binding of HCRT and ERAL1 1 0.00 3.06 0.87
30 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
31 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
32 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
33 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
34 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
35 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
36 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
37 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
38 INT142454 Npff Positive_regulation of Gtpbp4 1 0.56 0 0.78
39 INT142455 Binding of Npff and Gtpbp4 1 0.40 0 0.78
40 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
41 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
42 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
43 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
44 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
45 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
46 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
47 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
48 INT113931 Mors1 Positive_regulation of Gtpbp4 1 0.02 0 0.67
49 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
50 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
51 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
52 INT161387 Binding of PNOC and GTPBP4 1 0.03 1.05 0.59
53 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
54 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
55 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
56 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
57 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55
58 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54
59 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
60 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
61 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
62 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
63 INT81004 Htr1a Positive_regulation of Gtpbp4 1 0.20 0 0.5
64 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
65 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
66 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
67 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
68 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
69 INT122102 Npy Negative_regulation of Hcrt 1 0.19 0.1 0.47
70 INT92743 Binding of NF2 and LMOD1 1 0.00 0.08 0.46
71 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
72 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
73 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
74 INT169478 TGFB3 Positive_regulation of Tgfa 1 0.01 0.9 0.44
75 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
76 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
77 INT169465 TGFB3 Positive_regulation of MTG1 1 0.03 0.89 0.43
78 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
79 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
80 INT160048 INPPL1 Regulation of Gene_expression of AKT1 1 0.28 0.6 0.42
81 INT92744 Binding of ADRB2 and NF2 1 0.00 0.1 0.41
82 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
83 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
84 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
85 INT56876 Regulation of Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
86 INT56875 Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
87 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
88 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
89 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
90 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
91 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
92 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
93 INT324819 Hmgb1 Positive_regulation of Gene_expression of Maob 1 0.09 0.44 0.37
94 INT324827 Hmgb1 Positive_regulation of Bad 1 0.02 0.43 0.36
95 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
96 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
97 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
98 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
99 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
100 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
101 INT109282 Gdi2 Negative_regulation of Gtpbp4 1 0.01 0.13 0.32
102 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32
103 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
104 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
105 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
106 INT93464 Hcrt Negative_regulation of Pomc 1 0.18 0 0.31
107 INT88904 Binding of SCT and Hcrt 1 0.07 0 0.31
108 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
109 INT88903 Regulation of Binding of SCT and Hcrt 1 0.06 0 0.31
110 INT93465 Hcrt Negative_regulation of Localization of Gnrh1 1 0.36 0 0.31
111 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
112 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
113 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
114 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
115 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
116 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29
117 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
118 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
119 INT300552 Napa Positive_regulation of Gene_expression of TGFB1 1 0.01 0.88 0.29
120 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
121 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
122 INT71550 GTPBP4 Regulation of Localization of INS 1 0.00 0.16 0.28
123 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
124 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
125 INT64892 ANTXR1 Regulation of Gtpbp4 1 0.00 0.47 0.28
126 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
127 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
128 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
129 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
130 INT137032 Il6 Positive_regulation of Localization of Tgfb1 1 0.04 0.51 0.27
131 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
132 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
133 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
134 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
135 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
136 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
137 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
138 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
139 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
140 INT271450 Thy1 Regulation of TGFB1 1 0.00 0.62 0.25
141 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 0.23 0.2 0.25
142 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
143 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25
144 INT323610 Tlr4 Positive_regulation of Hmgb1 1 0.25 0.2 0.25
145 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
146 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
147 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
148 INT253765 Apex1 Positive_regulation of Hmgb1 1 0.09 1.27 0.24
149 INT343914 Hmgb1 Positive_regulation of Gene_expression of IL12A 1 0.01 0.41 0.24
150 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24
151 INT253771 Gopc Positive_regulation of Hmgb1 1 0.03 1.27 0.24
152 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24
153 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 0.05 0.41 0.24
154 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
155 INT253773 TNF Positive_regulation of Hmgb1 1 0.09 1.21 0.23
156 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
157 INT168710 Ifng Regulation of TGFB1 1 0.00 0.3 0.23
158 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
159 INT344833 Binding of Ager and Hmgb1 1 0.08 0.72 0.22
160 INT112596 Tgfb1 Negative_regulation of Negative_regulation of Mptp1 1 0.26 0.72 0.22
161 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
162 INT112595 Tgfb1 Negative_regulation of Gene_expression of Mptp1 1 0.27 0.72 0.22
163 INT146826 Binding of Galr1 and Gtpbp4 1 0.03 0.17 0.22
164 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21
165 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
166 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
167 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21
168 INT114905 TGFB1 Positive_regulation of Transcription of COL7A1 1 0.02 0.08 0.21
169 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
170 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
171 INT92692 Tgfb1 Positive_regulation of Gene_expression of Fn1 1 0.27 0.91 0.2
172 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
173 INT95896 Npy Positive_regulation of Positive_regulation of Gtpbp4 1 0.12 0 0.2
174 INT92693 Tgfb1 Positive_regulation of Fgf2 1 0.32 0.9 0.2
175 INT258289 Hmgb1 Positive_regulation of Tlr2 4 0.48 3.61 0.19
176 INT280260 Tgfb1 Positive_regulation of Cxcr1 1 0.07 1.78 0.19
177 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
178 INT14869 Binding of EGF and TGFB3 1 0.14 0.69 0.19
179 INT324815 Binding of Hmgb1 and Caprin1 1 0.01 0.65 0.19
180 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
181 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
182 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
183 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
184 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
185 INT280261 Tgfb1 Positive_regulation of Gene_expression of Cxcr1 1 0.05 1.81 0.19
186 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
187 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
188 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19
189 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
190 INT323613 Il1 Regulation of Localization of Hmgb1 1 0.10 0.75 0.19
191 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19
192 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18
193 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18
194 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18
195 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
196 INT275802 Hcrt Regulation of Rem1 1 0.20 0.95 0.17
197 INT85334 Agtr2 Regulation of Regulation of Tgfb1 1 0.23 0.68 0.17
198 INT215094 Il6 Positive_regulation of Hmgb1 1 0.18 1.84 0.17
199 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
200 INT245332 ATR Regulation of IL6 1 0.03 0.35 0.17

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of DNA replication. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of DNA replication. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
2 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97
3 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
4 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
5 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
6 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
7 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
8 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
9 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
10 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
11 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
12 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
13 INT21421 Regulation of Gtpbp4 15 0.30 2.7 13.49
14 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
15 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
16 INT67915 Negative_regulation of Gtpbp4 18 0.33 6.31 10.17
17 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
18 INT106056 Gene_expression of Hcrt 77 0.76 35.35 8.16
19 INT81153 Gene_expression of Hcrt 31 0.77 6.04 8.16
20 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
21 INT68434 Gene_expression of Gtpbp4 15 0.54 5.5 7.91
22 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
23 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
24 INT6341 Binding of Gtpbp4 11 0.44 1.54 7.3
25 INT77756 Positive_regulation of GTPBP4 16 0.11 2.6 7.29
26 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
27 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
28 INT185879 Gene_expression of CDC6 9 0.39 5.18 6.46
29 INT103723 Regulation of Positive_regulation of Gtpbp4 5 0.22 1.56 6.35
30 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
31 INT84779 Positive_regulation of Hcrt 9 0.70 1.27 6.21
32 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
33 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
34 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
35 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
36 INT60585 Regulation of TP53 59 0.59 54.55 5.21
37 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
38 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
39 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
40 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
41 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
42 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
43 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
44 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15
45 INT215085 Positive_regulation of Gene_expression of Hmgb1 17 0.63 16.81 4.13
46 INT74203 Positive_regulation of Positive_regulation of Gtpbp4 6 0.50 0.33 4.13
47 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
48 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4
49 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
50 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
51 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
52 INT93463 Localization of Hcrt 13 0.78 1.58 3.51
53 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
54 INT106057 Negative_regulation of Hcrt 27 0.57 15.5 3.47
55 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
56 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
57 INT88748 Binding of Hcrt 7 0.47 0 3.22
58 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
59 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
60 INT8103 Binding of TP53 46 0.44 40.2 2.96
61 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
62 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
63 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
64 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
65 INT113638 Negative_regulation of Hcrt 5 0.57 0.9 2.63
66 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
67 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
68 INT55952 Transcription of TP53 16 0.61 12.14 2.36
69 INT110139 Positive_regulation of Hcrt 7 0.67 2.14 2.26
70 INT81154 Gene_expression of HCRT 10 0.75 5.32 2.22
71 INT106055 Negative_regulation of Gene_expression of Hcrt 15 0.46 5.64 2.09
72 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
73 INT81152 Regulation of Hcrt 6 0.45 1.27 2.08
74 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
75 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
76 INT65855 Localization of TP53 18 0.76 17.08 1.89
77 INT68435 Regulation of Gene_expression of Gtpbp4 4 0.34 0.96 1.89
78 INT9297 Localization of Gtpbp4 4 0.17 0.88 1.89
79 INT306836 Negative_regulation of Gene_expression of CDC6 1 0.19 1.28 1.88
80 INT57618 Binding of GTPBP4 9 0.43 1.61 1.87
81 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
82 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
83 INT253755 Regulation of Hmgb1 7 0.55 6.23 1.8
84 INT4188 Binding of NF2 7 0.46 3.52 1.79
85 INT117585 Regulation of Hcrt 10 0.56 6.16 1.77
86 INT96823 Positive_regulation of Positive_regulation of GTPBP4 3 0.05 0.41 1.67
87 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
88 INT140621 Localization of Hcrt 7 0.73 2.6 1.64
89 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
90 INT151954 Positive_regulation of HCRT 2 0.67 1.79 1.56
91 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
92 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
93 INT306875 Localization of CDC6 1 0.34 1.51 1.52
94 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
95 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
96 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
97 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
98 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
99 INT172953 Binding of Trp53 33 0.37 20.76 1.41
100 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
101 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
102 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
103 INT151955 Regulation of HCRT 1 0.12 1.2 1.39
104 INT145221 Binding of Tp53 10 0.37 8.59 1.37
105 INT128019 Transcription of Hcrt 3 0.41 0.12 1.34
106 INT79099 Negative_regulation of Positive_regulation of Gtpbp4 4 0.20 0.06 1.31
107 INT219492 Negative_regulation of CDC6 2 0.20 1.74 1.31
108 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
109 INT57619 Gene_expression of GTPBP4 3 0.04 0.22 1.2
110 INT174156 Localization of Trp53 16 0.72 13.52 1.18
111 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
112 INT93168 Gene_expression of Ttf1 24 0.63 17.18 1.14
113 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
114 INT81440 Regulation of GTPBP4 3 0.02 0.09 1.1
115 INT113635 Positive_regulation of Localization of Hcrt 1 0.49 0.51 1.06
116 INT215077 Negative_regulation of Positive_regulation of Hmgb1 3 0.42 5.09 1.05
117 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
118 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
119 INT132833 Positive_regulation of Gene_expression of Hcrt 4 0.55 3.1 1.01
120 INT86798 Positive_regulation of Binding of Gtpbp4 1 0.29 0 1.01
121 INT306847 Positive_regulation of Gene_expression of CDC6 1 0.23 0.16 0.99
122 INT21109 Phosphorylation of Gtpbp4 2 0.22 0.28 0.97
123 INT215078 Negative_regulation of Gene_expression of Hmgb1 4 0.41 4.3 0.96
124 INT184992 Positive_regulation of CDC6 2 0.28 0.7 0.96
125 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
126 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
127 INT306882 Transcription of CDC6 1 0.24 0.57 0.92
128 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
129 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
130 INT127709 Positive_regulation of Gene_expression of Hcrt 3 0.45 0.55 0.84
131 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
132 INT225221 Negative_regulation of Nf2 1 0.57 18.06 0.83
133 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
134 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
135 INT102262 Localization of NF2 1 0.14 0.6 0.79
136 INT125627 Gene_expression of TTF1 11 0.78 12.68 0.78
137 INT14871 Binding of TGFB3 3 0.13 1.2 0.78
138 INT190522 Regulation of Gene_expression of Hmgb1 1 0.39 1.47 0.77
139 INT291617 Negative_regulation of Transcription of TGFB1 2 0.15 0.61 0.76
140 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
141 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
142 INT90790 Regulation of Localization of Tgfb1 2 0.29 0.46 0.75
143 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
144 INT99281 Negative_regulation of HCRT 3 0.57 2.26 0.71
145 INT337046 Positive_regulation of Binding of Tgfb1 1 0.30 1.1 0.69
146 INT121302 Positive_regulation of Localization of Tgfb1 5 0.07 1.91 0.67
147 INT114909 Negative_regulation of Localization of TGFB1 5 0.36 1.37 0.66
148 INT103237 Regulation of Localization of Gtpbp4 2 0.03 0.19 0.64
149 INT111891 Regulation of Transcription of Tgfb1 1 0.04 0.68 0.64
150 INT202848 Gene_expression of Nf2 5 0.59 4.93 0.63
151 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
152 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
153 INT114910 Negative_regulation of Positive_regulation of TGFB1 3 0.34 0.92 0.6
154 INT173891 Positive_regulation of Phosphorylation of TGFB1 4 0.49 2 0.59
155 INT138140 Protein_catabolism of Tgfb1 2 0.09 0.87 0.59
156 INT91896 Negative_regulation of Gene_expression of Gtpbp4 2 0.13 1.33 0.58
157 INT291268 Gene_expression of Atr 1 0.06 1.48 0.57
158 INT213651 Binding of HCRT 2 0.36 1.08 0.56
159 INT109643 Localization of HCRT 2 0.78 0 0.55
160 INT69683 Positive_regulation of Transcription of Tgfb1 1 0.67 0 0.53
161 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
162 INT215070 Regulation of Localization of Hmgb1 4 0.26 2.23 0.49
163 INT82266 Transcription of Hcrt 4 0.68 2.77 0.46
164 INT129285 Negative_regulation of Localization of Hcrt 1 0.57 0 0.45
165 INT352592 Positive_regulation of Negative_regulation of Hmgb1 1 0.44 1.31 0.42
166 INT160053 Gene_expression of INPPL1 1 0.55 0.6 0.42
167 INT27659 Localization of TGFB3 3 0.29 0.52 0.4
168 INT160456 Positive_regulation of Localization of Gtpbp4 1 0.03 0.19 0.4
169 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
170 INT127710 Negative_regulation of Gene_expression of Hcrt 2 0.39 0.34 0.37
171 INT88897 Regulation of Binding of Hcrt 1 0.60 0 0.37
172 INT125628 Negative_regulation of Gene_expression of TTF1 1 0.43 1.63 0.36
173 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
174 INT69680 Positive_regulation of Positive_regulation of Tgfb1 3 0.67 1.04 0.35
175 INT258283 Positive_regulation of Positive_regulation of Hmgb1 3 0.44 3.1 0.3
176 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
177 INT331591 Transcription of Hmgb1 1 0.28 0.92 0.3
178 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
179 INT245337 Gene_expression of ATR 3 0.27 2.06 0.29
180 INT14873 Positive_regulation of Gene_expression of TGFB3 2 0.25 1.14 0.29
181 INT258092 Regulation of Gene_expression of Hcrt 2 0.44 2.6 0.29
182 INT225219 Positive_regulation of Gene_expression of Nf2 1 0.43 1.27 0.27
183 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
184 INT91549 Regulation of Binding of GTPBP4 1 0.05 0.09 0.26
185 INT184987 Regulation of CDC6 2 0.12 0.27 0.25
186 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
187 INT165096 Positive_regulation of Binding of GTPBP4 1 0.11 0 0.25
188 INT251228 Phosphorylation of Tgfb1 4 0.15 1.18 0.24
189 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
190 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
191 INT299545 Positive_regulation of Binding of TGFB1 2 0.06 1.08 0.22
192 INT147840 Gene_expression of Tgfb3 1 0.03 0 0.22
193 INT147841 Positive_regulation of Gene_expression of Tgfb3 1 0.02 0 0.22
194 INT61823 Positive_regulation of TGFB3 2 0.01 1.64 0.2
195 INT258096 Binding of Hcrt 5 0.36 3.2 0.18
196 INT85330 Positive_regulation of Regulation of Tgfb1 1 0.41 0.67 0.17
197 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
198 INT122201 Binding of Tgfb1 1 0.16 0.17 0.17
199 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
200 INT105012 Negative_regulation of Atr 1 0.34 0.35 0.16
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