GO:0008201

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Name heparin binding
Categary Function
Go Slim No
Go Link GO:0008201
Unique Molecular Interactions 2910
Total Molecular Interactions 4334
Total Single Events 36933
Pain Genes Associated 159

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for heparin binding. They are ordered first by their pain relevance and then by number of times they were reported for heparin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
2 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
3 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
4 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
5 INT150632 Ea1 Negative_regulation of Mpo 1 0.17 1.55 2.9
6 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
7 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
8 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
9 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
10 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
11 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
12 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
13 INT182200 Binding of CXCR5 and CXCL13 1 0.37 2.89 2.07
14 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
15 INT334532 Sema3a Negative_regulation of Gene_expression of Nrp1 1 0.19 7.58 2
16 INT14991 SFTPA1 Positive_regulation of Localization of MPO 1 0.11 1.65 1.92
17 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
18 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
19 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
20 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
21 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
22 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
23 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
24 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
25 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
26 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
27 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
28 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
29 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
30 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
31 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
32 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
33 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53
34 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
35 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
36 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
37 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
38 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
39 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
40 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
41 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27
42 INT343949 SERPINE2 Positive_regulation of Positive_regulation of Slco1c1 1 0.00 0.59 1.27
43 INT219686 Binding of CEL and COPD 1 0.12 11.35 1.26
44 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26
45 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
46 INT132465 Ltf Positive_regulation of Nos1 1 0.35 0.05 1.24
47 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
48 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
49 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
50 INT62019 CSF2 Regulation of ELANE 1 0.03 0.47 1.21
51 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
52 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
53 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14
54 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14
55 INT76199 CASP1 Positive_regulation of CEL 1 0.06 0.32 1.14
56 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
57 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
58 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
59 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
60 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
61 INT343950 SERPINE2 Positive_regulation of Slco1c1 1 0.00 1.63 1.07
62 INT150784 ZNF398 Positive_regulation of Localization of THBS3 1 0.07 1.02 1.07
63 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
64 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
65 INT116777 Psma5 Positive_regulation of Binding of Fn1 1 0.01 1.24 1.06
66 INT312097 ELANE Regulation of ALOX5 1 0.08 1.75 1.05
67 INT145906 Elane Regulation of Transcription of Oprm1 1 0.10 0.14 1.04
68 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04
69 INT132464 Ltf Negative_regulation of Positive_regulation of Nos1 1 0.33 0 1.03
70 INT106706 POMC Negative_regulation of Binding of FN1 1 0.19 0.79 1.02
71 INT144661 Dnm1 Negative_regulation of Binding of Hbegf 1 0.24 0 1.01
72 INT101317 Binding of Selplg and Selp 1 0.02 3.72 1.01
73 INT112163 Calca Positive_regulation of Mpo 1 0.49 1.23 1
74 INT147506 Binding of Ncam1 and Gtf3a 1 0.03 0.88 0.99
75 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 0.30 0.38 0.99
76 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98
77 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98
78 INT73680 KNG1 Positive_regulation of ALB 1 0.51 0.38 0.98
79 INT62017 ELANE Positive_regulation of Localization of ACOT1 1 0.05 0.35 0.98
80 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97
81 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97
82 INT303690 KNG1 Positive_regulation of CPOX 1 0.01 0.76 0.96
83 INT66714 Negative_regulation of Binding of BDKRB1 and KNG1 1 0.13 0.22 0.96
84 INT272984 Il6 Positive_regulation of Gene_expression of Itgam 1 0.24 0.78 0.96
85 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
86 INT135585 CSF2 Regulation of CCL2 1 0.13 2.51 0.95
87 INT182207 Binding of CXCR2 and CXCL13 1 0.42 1.26 0.95
88 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
89 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
90 INT182210 Binding of CXCR4 and CXCL13 1 0.32 1.25 0.95
91 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
92 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
93 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
94 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
95 INT182189 Binding of CXCL1 and CXCL13 1 0.14 1.24 0.93
96 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
97 INT182209 Binding of CXCL12 and CXCL13 1 0.30 1.24 0.93
98 INT182196 Binding of IL8 and CXCL13 1 0.27 1.24 0.93
99 INT182204 Binding of CXCL5 and CXCL13 1 0.30 1.24 0.93
100 INT13193 FPR1 Positive_regulation of ELANE 3 0.44 1.22 0.92
101 INT129003 Ccl2 Positive_regulation of ANTXRL 1 0.00 0.68 0.92
102 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
103 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
104 INT159993 App Regulation of Gene_expression of Bace1 1 0.46 0.32 0.92
105 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
106 INT156989 LPA Positive_regulation of Gene_expression of EFNB1 1 0.00 0.91 0.92
107 INT13282 Fgf2 Regulation of Ngf 1 0.66 0.21 0.91
108 INT66334 Fgf2 Regulation of Fgf1 1 0.37 0.17 0.9
109 INT13280 Ngf Regulation of Fgf2 1 0.48 0.2 0.9
110 INT84369 Ngf Positive_regulation of KNG1 1 0.04 0.29 0.89
111 INT325807 CXCL13 Positive_regulation of CISH 1 0.16 3.65 0.89
112 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
113 INT96008 Binding of KNG1 and EBP 1 0.01 0.15 0.88
114 INT96010 KNG1 Positive_regulation of Binding of MTG1 1 0.32 0.15 0.88
115 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
116 INT96009 KNG1 Positive_regulation of MTG1 1 0.32 0.15 0.88
117 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
118 INT97738 Mdk Positive_regulation of Mapk3 1 0.08 0.66 0.87
119 INT66333 Fgf2 Negative_regulation of Positive_regulation of Npy 1 0.20 0.17 0.85
120 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85
121 INT107698 FN1 Positive_regulation of Gene_expression of CPOX 1 0.13 0.26 0.84
122 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
123 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
124 INT302379 Crp Positive_regulation of Gene_expression of Ccl2 1 0.10 4.58 0.84
125 INT183175 Binding of FGF2 and NUDT6 1 0.07 1.07 0.84
126 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83
127 INT32441 POMC Positive_regulation of ELANE 1 0.13 0.09 0.83
128 INT48384 CSF2 Regulation of Gene_expression of SELL 1 0.17 0.4 0.83
129 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
130 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
131 INT225690 KNG1 Positive_regulation of TRPV1 1 0.42 0.7 0.83
132 INT48380 CSF3 Regulation of Gene_expression of SELL 1 0.41 0.4 0.83
133 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
134 INT46084 Binding of SELL and Penk 1 0.02 0.06 0.83
135 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
136 INT193322 KNG1 Positive_regulation of Prh1 1 0.00 0.51 0.83
137 INT46076 Binding of MET and SELL 1 0.39 0.06 0.83
138 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
139 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
140 INT19299 ANG Regulation of AVP 1 0.25 0 0.82
141 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
142 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
143 INT90381 Binding of GH1 and LAMC2 1 0.34 0.05 0.81
144 INT99578 Binding of CEL and Kit 1 0.04 1.07 0.81
145 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
146 INT110726 Binding of ALB and LTF 1 0.01 0 0.81
147 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 0.01 1.2 0.79
148 INT127383 Neo1 Regulation of Localization of Mpo 1 0.14 0.7 0.79
149 INT21233 Ngf Regulation of Fgf1 1 0.46 0.09 0.79
150 INT150636 Binding of KNG1 and CD177 1 0.10 0.37 0.79
151 INT140920 Btnl2 Negative_regulation of Itgam 1 0.02 0.88 0.79
152 INT239671 Binding of Ccl2 and Gtf3a 1 0.02 1.34 0.79
153 INT16507 Binding of LPA and Crp 1 0.00 0.78 0.78
154 INT117604 AKR1C1 Negative_regulation of Positive_regulation of Mpo 1 0.00 1.45 0.78
155 INT16494 Binding of LPA and Serpinf2 1 0.00 0.78 0.78
156 INT351364 LPA Positive_regulation of Trpv1 1 0.02 1.15 0.78
157 INT16492 Positive_regulation of Binding of LPA and Serpinf2 1 0.00 0.78 0.78
158 INT16506 Positive_regulation of Binding of LPA and Crp 1 0.00 0.78 0.78
159 INT16498 Binding of ADRA1D and LPA 1 0.10 0.78 0.78
160 INT16497 Positive_regulation of Binding of ADRA1D and LPA 1 0.10 0.78 0.78
161 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
162 INT113546 Binding of FN1 and ITGA3 1 0.03 2.12 0.77
163 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
164 INT147913 Phosphorylation of Camk2a Positive_regulation of Binding of Lpl 1 0.10 0 0.77
165 INT149495 PNOC Negative_regulation of CCL2 1 0.11 0.16 0.77
166 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
167 INT129415 KNG1 Positive_regulation of Trpv1 1 0.05 0.39 0.76
168 INT113549 Binding of VTN and alphavbeta3 integrin receptor 1 0.09 2.05 0.76
169 INT123556 Shfm1 Regulation of Mpo 1 0.09 0.88 0.76
170 INT107028 KNG1 Regulation of Des 1 0.01 1.7 0.76
171 INT158607 Ns5atp9 Positive_regulation of Mpo 1 0.35 1.85 0.75
172 INT332699 Binding of KNG1 and TRGC1 1 0.16 3.37 0.75
173 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
174 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
175 INT4917 Binding of Pcolce and Tac2 1 0.03 0 0.74
176 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
177 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74
178 INT170992 Binding of FN1 and MMRN1 3 0.01 2.13 0.73
179 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
180 INT312101 ELANE Regulation of ALOX5AP 1 0.21 1.11 0.73
181 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
182 INT177359 Serpinc1 Positive_regulation of CSRP1 1 0.00 0.97 0.72
183 INT48387 CSF2 Positive_regulation of SELL 1 0.18 0.24 0.71
184 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
185 INT120017 CCL2 Positive_regulation of CCL3 1 0.01 0.99 0.7
186 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
187 INT120035 CCL2 Positive_regulation of Prap1 1 0.00 0.99 0.7
188 INT260832 Binding of NRP2 and Nrp1 1 0.00 2.32 0.7
189 INT95148 CEL Regulation of IL1B 1 0.24 0.88 0.7
190 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
191 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
192 INT121458 KNG1 Positive_regulation of Localization of Trpv1 1 0.16 0.43 0.69
193 INT126779 Binding of Serpinc1 and F8 1 0.00 1.52 0.69
194 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
195 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
196 INT126781 Binding of F10 and Serpinc1 1 0.00 1.51 0.69
197 INT351367 LPA Regulation of Trpv1 1 0.01 0.83 0.69
198 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
199 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
200 INT130717 Binding of OPRM1 and Positive_regulation of Localization of CCL2 1 0.00 0.72 0.68

Single Events

The table below shows the top 100 pain related interactions that have been reported for heparin binding. They are ordered first by their pain relevance and then by number of times they were reported in heparin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
3 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
4 INT65500 Gene_expression of App 605 0.78 429.94 98.31
5 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
6 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47
7 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
8 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
9 INT7134 Localization of KNG1 127 0.79 65.73 67.97
10 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
11 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
12 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74
13 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
14 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
15 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
16 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
17 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57
18 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03
19 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
20 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72
21 INT65698 Localization of CCL2 118 0.81 77.54 32.69
22 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
23 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
24 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
25 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23
26 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
27 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26
28 INT9650 Gene_expression of LPA 141 0.75 104.57 29
29 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
30 INT82882 Localization of Ccl2 61 0.80 41.96 28
31 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94
32 INT3076 Regulation of KNG1 52 0.60 20.39 27.89
33 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
34 INT3167 Binding of KNG1 48 0.48 23.26 26.77
35 INT2609 Localization of ELANE 111 0.81 50.22 26.63
36 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42
37 INT66025 Gene_expression of Itgam 61 0.78 31.26 26.08
38 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
39 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
40 INT49141 Gene_expression of Selp 157 0.78 85.22 24.78
41 INT58301 Positive_regulation of Mpo 87 0.70 80.19 23.99
42 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
43 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58
44 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
45 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09
46 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79
47 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
48 INT11625 Localization of App 98 0.78 55.46 20.86
49 INT78901 Localization of CCL5 67 0.78 40.79 20.59
50 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48
51 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
52 INT16794 Binding of App 103 0.48 64.87 19.79
53 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
54 INT6993 Negative_regulation of Mpo 72 0.59 61.83 19.51
55 INT65502 Regulation of App 77 0.62 52.05 19.44
56 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99
57 INT18672 Gene_expression of Ncam1 54 0.78 36.64 18.79
58 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
59 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
60 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
61 INT61519 Gene_expression of Mpo 112 0.78 89.29 18.22
62 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
63 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
64 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85
65 INT2216 Gene_expression of SELL 92 0.77 59.29 17.71
66 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
67 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
68 INT66023 Positive_regulation of Gene_expression of Itgam 25 0.64 12.65 16.56
69 INT98647 Positive_regulation of Mdk 65 0.59 32.93 15.67
70 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12
71 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
72 INT54052 Gene_expression of App 33 0.78 25.08 14.7
73 INT5904 Localization of MPO 62 0.81 36.37 14.64
74 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49
75 INT11069 Positive_regulation of Pf4 35 0.68 27.7 13.96
76 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89
77 INT20066 Gene_expression of Mdk 38 0.76 21.41 13.4
78 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87
79 INT71510 Positive_regulation of Selp 47 0.68 30.43 12.8
80 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
81 INT29745 Binding of APP 47 0.48 26.49 12.4
82 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38
83 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
84 INT4460 Regulation of Mpo 44 0.62 31.16 12.11
85 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09
86 INT182240 Gene_expression of CXCL13 25 0.59 22.77 11.96
87 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93
88 INT5649 Negative_regulation of Positive_regulation of Mpo 31 0.59 26.62 11.92
89 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9
90 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64
91 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48
92 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47
93 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15
94 INT14962 Gene_expression of Pf4 27 0.76 22.48 10.88
95 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83
96 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
97 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3
98 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
99 INT32344 Localization of LTF 30 0.80 15.28 10.09
100 INT29740 Gene_expression of ANG 55 0.78 24.53 9.86
101 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83
102 INT82829 Gene_expression of COMP 104 0.78 57 9.81
103 INT106200 Binding of Ccl2 22 0.42 16.7 9.75
104 INT12563 Localization of Mpo 33 0.81 20.99 9.58
105 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
106 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45
107 INT41569 Regulation of APP 32 0.62 17.15 9.4
108 INT140224 Localization of Ccl2 32 0.72 26.91 9.39
109 INT68133 Localization of Fgf2 36 0.81 15.37 9.14
110 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1
111 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08
112 INT38173 Gene_expression of Ang 40 0.75 32.63 8.86
113 INT108098 Positive_regulation of Itgam 19 0.70 8.09 8.86
114 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83
115 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82
116 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51
117 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35
118 INT127378 Localization of Mpo 21 0.78 26.36 8.28
119 INT56223 Positive_regulation of MPO 35 0.70 43 8.2
120 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
121 INT92680 Gene_expression of Fgf2 59 0.77 28.11 8.12
122 INT51458 Negative_regulation of Gene_expression of Selp 29 0.57 12.64 8.1
123 INT15725 Positive_regulation of Fn1 17 0.67 14.93 8.03
124 INT26551 Positive_regulation of Gene_expression of KNG1 19 0.67 11.05 7.98
125 INT67424 Positive_regulation of Gene_expression of Selp 36 0.68 17.08 7.95
126 INT153814 Localization of LPA 19 0.65 18.25 7.68
127 INT76892 Gene_expression of FGFR1 45 0.69 23.6 7.56
128 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
129 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
130 INT56031 Positive_regulation of App 25 0.69 13.46 7.37
131 INT14732 Positive_regulation of FN1 46 0.69 31.17 7.33
132 INT30777 Negative_regulation of SELL 20 0.56 18.05 7.32
133 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25
134 INT47994 Negative_regulation of Lipg 45 0.50 27.19 7.24
135 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
136 INT82881 Regulation of Ccl2 19 0.57 15.29 7.19
137 INT63169 Positive_regulation of Gene_expression of Selp 35 0.69 21.95 7.16
138 INT2605 Regulation of ELANE 39 0.61 18.22 7.11
139 INT152030 Gene_expression of Postn 10 0.55 8.09 7.08
140 INT197493 Localization of Apoe 61 0.79 27.48 7.06
141 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06
142 INT76120 Gene_expression of Ptprc 102 0.59 30.42 7.02
143 INT16722 Negative_regulation of MPO 25 0.59 18.55 6.99
144 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
145 INT50669 Negative_regulation of Ptn 15 0.58 5.56 6.88
146 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84
147 INT181348 Localization of Ccl5 24 0.65 19.55 6.8
148 INT245173 Gene_expression of MDK 81 0.49 51.08 6.78
149 INT81493 Transcription of CCL2 20 0.65 13.63 6.78
150 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
151 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
152 INT133889 Gene_expression of Adamts1 78 0.76 48.05 6.58
153 INT120895 Binding of CCL2 22 0.37 15.86 6.55
154 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51
155 INT6052 Gene_expression of Ptn 12 0.78 8.4 6.5
156 INT64052 Positive_regulation of FGFR1 26 0.52 28.47 6.36
157 INT2925 Positive_regulation of Positive_regulation of Mpo 21 0.70 16.76 6.36
158 INT63170 Positive_regulation of Selp 27 0.68 24.1 6.3
159 INT92504 Negative_regulation of Ccl2 17 0.43 8.98 6.29
160 INT82828 Positive_regulation of COMP 45 0.61 35.12 6.2
161 INT64689 Positive_regulation of Gene_expression of Fgf2 30 0.70 12.05 6.2
162 INT39047 Gene_expression of PGF 34 0.78 17.48 6
163 INT116420 Localization of Elane 16 0.14 7.8 6
164 INT19941 Negative_regulation of Pf4 13 0.42 10.35 5.97
165 INT63042 Binding of Apoe 59 0.48 31.23 5.88
166 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
167 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
168 INT131378 Negative_regulation of FN1 20 0.35 33.98 5.85
169 INT236839 Positive_regulation of CXCL13 14 0.44 19.27 5.81
170 INT36921 Regulation of Mdk 14 0.26 6.49 5.8
171 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
172 INT52904 Positive_regulation of LTF 21 0.67 15.58 5.78
173 INT10147 Gene_expression of Serpinc1 28 0.76 17.73 5.77
174 INT12157 Positive_regulation of SELL 16 0.67 14.54 5.74
175 INT21647 Negative_regulation of Positive_regulation of KNG1 11 0.43 5.54 5.73
176 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68
177 INT13170 Gene_expression of Comp 25 0.74 8.68 5.62
178 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
179 INT83290 Regulation of Gene_expression of Ccl2 8 0.59 9.06 5.56
180 INT63507 Gene_expression of SERPINE2 8 0.70 8.35 5.56
181 INT85075 Phosphorylation of Mdk 22 0.61 10.29 5.55
182 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5
183 INT81326 Positive_regulation of Gene_expression of Ang 17 0.67 18.5 5.46
184 INT5903 Negative_regulation of Localization of MPO 10 0.59 5.71 5.45
185 INT15173 Positive_regulation of Gene_expression of Itgam 59 0.49 21.89 5.43
186 INT140223 Regulation of Ccl2 15 0.45 13.1 5.41
187 INT19768 Negative_regulation of LAMC2 11 0.57 10.54 5.32
188 INT107173 Phosphorylation of App 20 0.82 12.64 5.3
189 INT49801 Positive_regulation of SELP 21 0.48 21.34 5.25
190 INT10100 Binding of ELANE 22 0.47 15.32 5.19
191 INT92679 Positive_regulation of Fgf2 13 0.69 11.43 5.18
192 INT97905 Positive_regulation of FGF2 33 0.70 26.74 5.17
193 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
194 INT181363 Regulation of Ccl5 16 0.46 13.65 5.09
195 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
196 INT61252 Negative_regulation of Gene_expression of Itgam 38 0.54 16.48 5.01
197 INT20200 Positive_regulation of Serpinc1 25 0.68 17.08 4.98
198 INT181362 Negative_regulation of Ccl5 21 0.40 15.63 4.96
199 INT161220 Binding of Ccl2 17 0.46 17.63 4.94
200 INT23245 Positive_regulation of Gene_expression of CEL 19 0.69 14.81 4.92
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