GO:0008209

From wiki-pain
Jump to: navigation, search
Name androgen metabolic process
Categary Process
Go Slim No
Go Link GO:0008209
Unique Molecular Interactions 502
Total Molecular Interactions 629
Total Single Events 6358
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for androgen metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for androgen metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
2 INT33756 Akr1d1 Positive_regulation of Npr1 3 0.01 0 2.05
3 INT33759 Hmmr Positive_regulation of Akr1d1 1 0.00 0 1.58
4 INT7791 Akr1d1 Regulation of Nts 1 0.03 0 1.58
5 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
6 INT7796 Akr1d1 Regulation of Npy 1 0.03 0 1.57
7 INT100784 RYBP Positive_regulation of CYP3A4 1 0.44 0 1.54
8 INT7797 Akr1d1 Regulation of Sst 1 0.02 0 1.54
9 INT123899 Binding of CYP3A4 and UGT2B7 1 0.52 0 1.46
10 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
11 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
12 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
13 INT81097 Akr1d1 Regulation of Localization of Abat 1 0.00 0 1.2
14 INT13203 Oprd1 Negative_regulation of Akr1d1 1 0.01 0 1.18
15 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
16 INT13204 Binding of Npr1 and Akr1d1 1 0.00 0 1.14
17 INT264988 Binding of CYP2C19 and CYP3A4 1 0.18 0.72 1.09
18 INT264987 Binding of CYP2C9 and CYP3A4 1 0.19 0.71 1.08
19 INT97721 Akr1d1 Regulation of Gene_expression of Penk 1 0.00 0 0.98
20 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
21 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
22 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
23 INT80601 Akr1d1 Regulation of Positive_regulation of Fos 1 0.06 0 0.94
24 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
25 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
26 INT7799 Akr1d1 Regulation of Positive_regulation of Ptgdr 1 0.01 0 0.86
27 INT261461 Positive_regulation of Akr1d1 Regulation of Sftpd 1 0.01 0 0.86
28 INT261458 Akr1d1 Regulation of Sftpd 1 0.01 0 0.82
29 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
30 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
31 INT346133 RAMP2 Regulation of ADM 1 0.13 2.06 0.78
32 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77
33 INT261447 Sftpd Positive_regulation of Akr1d1 1 0.01 0 0.77
34 INT82039 Akr1d1 Positive_regulation of Phosphorylation of Ppp1r1b 1 0.02 0 0.74
35 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
36 INT7792 Akr1d1 Regulation of Gene_expression of Npy 1 0.02 0 0.65
37 INT190211 Adm Regulation of MMP12 1 0.29 0 0.65
38 INT261453 Binding of Akr1d1 and Ptgdr 1 0.00 0.56 0.65
39 INT82038 Positive_regulation of Akr1d1 Positive_regulation of Phosphorylation of Ppp1r1b 1 0.02 0 0.64
40 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
41 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
42 INT315334 Binding of CYP3A4 and CDIPT 3 0.04 0.85 0.59
43 INT63161 Akr1d1 Regulation of Gene_expression of Pdyn 1 0.01 0 0.59
44 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
45 INT108441 Adm Positive_regulation of Sst 1 0.40 0 0.54
46 INT54485 Positive_regulation of Akr1d1 Positive_regulation of Gene_expression of Rabep2 1 0.00 0 0.53
47 INT346146 ADM Positive_regulation of Gene_expression of PERP 1 0.02 1.54 0.51
48 INT20580 Drd2 Regulation of Akr1d1 1 0.02 0.26 0.51
49 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
50 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
51 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
52 INT7291 Akr1d1 Regulation of Regulation of Penk 1 0.01 0 0.48
53 INT195192 Akr1d1 Regulation of Msn 1 0.01 0.34 0.47
54 INT141964 Binding of ADM and RAMP1 1 0.30 2.63 0.47
55 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
56 INT123897 Binding of CYP3A4 and SLC35A2 1 0.39 0 0.45
57 INT108440 Adm Regulation of Localization of Sst 1 0.41 0 0.45
58 INT48038 Adm Regulation of Calca 1 0.31 0.14 0.42
59 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42
60 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
61 INT346151 Binding of ADM and GPER 1 0.01 0.99 0.41
62 INT123898 CYP3A4 Regulation of UGT2B7 1 0.22 0 0.41
63 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
64 INT346150 Binding of ADM and FN1 1 0.10 0.93 0.39
65 INT346140 Positive_regulation of Binding of ADM and MMRN1 1 0.04 0.93 0.39
66 INT346139 Binding of ADM and MMRN1 1 0.03 0.93 0.39
67 INT346135 Positive_regulation of Binding of ADM and FN1 1 0.13 0.93 0.39
68 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
69 INT117361 Binding of Esr1 and sea 1 0.02 1.38 0.38
70 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
71 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
72 INT117359 Binding of Esr1 and Wbc1 1 0.00 1.38 0.37
73 INT187064 ARSD Negative_regulation of CYP19A1 1 0.22 0.7 0.35
74 INT346145 Binding of ADM and TPX2 1 0.01 1.05 0.35
75 INT291555 Binding of ESR1 and Dlat 1 0.01 0.6 0.35
76 INT261462 Akr1d1 Positive_regulation of Hrasls 1 0.00 0.3 0.33
77 INT291554 Binding of ESR1 and St8sia2 1 0.01 0.49 0.33
78 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.97 0.32
79 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
80 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31
81 INT148342 Hsd17b6 Negative_regulation of Oxt 1 0.21 0.37 0.31
82 INT242399 Cyp19a1 Negative_regulation of Gene_expression of Bad 1 0.00 1.32 0.31
83 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
84 INT309156 Esr1 Regulation of Gene_expression of Dlat 1 0.05 1.06 0.3
85 INT132984 CYP3A4 Positive_regulation of Gene_expression of PPP4C 1 0.44 0 0.3
86 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
87 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
88 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
89 INT134927 CYP19A1 Positive_regulation of Gene_expression of MME 1 0.30 1.04 0.28
90 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
91 INT134930 MME Positive_regulation of Gene_expression of CYP19A1 1 0.30 1.04 0.28
92 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
93 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
94 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27
95 INT51858 Akr1d1 Positive_regulation of Phosphorylation of Creb1 1 0.01 0 0.27
96 INT282501 Negative_regulation of Cyp19a1 Negative_regulation of Gene_expression of Aaiq4 1 0.01 0.6 0.27
97 INT64290 Akr1d1 Regulation of Penk 1 0.00 0 0.26
98 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
99 INT78780 Binding of Calca and Adm 1 0.32 0.07 0.26
100 INT78781 Binding of Adm and Calca 1 0.01 0.07 0.26
101 INT262227 Nr1h4 Regulation of Transcription of CYP3A4 1 0.08 0.12 0.26
102 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26
103 INT272997 Binding of CYP3A4 and IL33 1 0.03 0 0.25
104 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25
105 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
106 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25
107 INT182349 Binding of Ms4a1 and Esr1 1 0.04 1.26 0.25
108 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24
109 INT262229 Binding of CYP3A4 and Casr 1 0.03 0.37 0.24
110 INT85011 ADM Regulation of CALCRL 1 0.06 0 0.24
111 INT309160 Binding of Esr1 and Edc4 1 0.03 0.34 0.24
112 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
113 INT64291 Akr1d1 Regulation of Slc3a1 1 0.01 0 0.23
114 INT346134 ADM Regulation of Gene_expression of MMRN1 1 0.04 1.29 0.23
115 INT64289 Slc3a1 Regulation of Akr1d1 1 0.01 0 0.23
116 INT63198 POMC Positive_regulation of ESR1 1 0.14 0.3 0.23
117 INT115729 Binding of CYP3A7 and CYP3A4 1 0.44 0.05 0.23
118 INT78782 Binding of Adm and Adm 1 0.01 0.07 0.23
119 INT346143 ADM Regulation of Gene_expression of TPX2 1 0.02 1.29 0.23
120 INT270135 Binding of ESR1 and RALA 1 0.11 0.37 0.22
121 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
122 INT318039 CDIPT Positive_regulation of CYP3A4 1 0.06 0.06 0.2
123 INT145140 Negative_regulation of CPOX Negative_regulation of Gene_expression of CYP19A1 1 0.13 0.47 0.2
124 INT308645 Binding of Esr1 and Itpr3 1 0.00 0 0.2
125 INT262224 Sfn Negative_regulation of Transcription of CYP3A4 1 0.06 0.58 0.2
126 INT90772 Binding of AKR1C4 and AKR1C1 1 0.39 0.08 0.2
127 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
128 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19
129 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19
130 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
131 INT197618 Binding of Esr1 and Ppt1 1 0.01 0 0.18
132 INT52306 Nr3c1 Negative_regulation of Transcription of Penk 1 0.26 0 0.18
133 INT330986 CYP2C9 Positive_regulation of Gene_expression of CYP3A4 1 0.39 0 0.18
134 INT173932 Binding of Esr1 and Il6 1 0.03 0.11 0.18
135 INT151895 Binding of CYP3A4 and GBE1 1 0.01 0.24 0.18
136 INT172254 Binding of ADM and TAS2R14 1 0.02 0 0.17
137 INT19042 ESR1 Positive_regulation of GGT5 1 0.03 0.6 0.17
138 INT19045 ESR1 Positive_regulation of Salpa1 1 0.02 0.6 0.17
139 INT85828 CYP3A4 Negative_regulation of CYP2D6 1 0.47 0.06 0.16
140 INT261460 Binding of Sftpd and Akr1d1 1 0.01 0.43 0.16
141 INT151894 NR1I2 Positive_regulation of CYP3A4 1 0.19 0.23 0.16
142 INT309154 Esr1 Positive_regulation of Gsdmc 1 0.01 0.44 0.15
143 INT273561 Binding of CYP1A1 and CYP3A4 1 0.02 0.12 0.15
144 INT309155 Negative_regulation of Esr1 Positive_regulation of Gsdmc 1 0.01 0.45 0.15
145 INT172245 Binding of ADM and NCOR2 1 0.01 0 0.15
146 INT172236 Binding of ADM and APLNR 1 0.06 0 0.14
147 INT181752 Binding of CPOX and ESR1 1 0.02 0.89 0.14
148 INT105913 Adm Negative_regulation of Adm 1 0.01 0 0.14
149 INT262231 Sfn Negative_regulation of Gene_expression of CYP3A4 1 0.06 0.26 0.14
150 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14
151 INT262232 Nr1i2 Positive_regulation of Gene_expression of CYP3A4 1 0.17 0.26 0.14
152 INT343027 Binding of CYP3A4 and Azi1 1 0.02 0.75 0.14
153 INT72029 Binding of ADM and IAPP 1 0.12 0.26 0.13
154 INT297312 Esr1 Positive_regulation of Scap 1 0.00 1.58 0.13
155 INT262228 Nr1i2 Positive_regulation of Transcription of CYP3A4 1 0.17 0.27 0.13
156 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13
157 INT86429 Binding of Hspb1 and Esr1 1 0.19 0.26 0.13
158 INT262226 Positive_regulation of Nr1i2 Positive_regulation of CYP3A4 1 0.17 0.68 0.12
159 INT236588 Binding of Esr1 and Ins1 1 0.05 0.73 0.12
160 INT341827 Binding of ESR1 and TNC 1 0.14 0.63 0.11
161 INT97081 CYP3A4 Regulation of HAGH 1 0.02 0 0.11
162 INT341775 DBT Regulation of Binding of ESR1 1 0.02 0.1 0.11
163 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11
164 INT220114 Tnfrsf1a Positive_regulation of Esr1 1 0.14 1.14 0.1
165 INT206856 Binding of Adm and Calcrl 1 0.04 1.76 0.1
166 INT179343 Adm Positive_regulation of Pscs 1 0.33 0.51 0.1
167 INT155221 Binding of CYP3A4 and PNPLA4 1 0.09 0 0.1
168 INT237819 Binding of Esr1 and soc 1 0.04 0 0.1
169 INT279407 Binding of ESR1 and IGKV2-19 1 0.02 0.4 0.1
170 INT125000 Binding of Esr1 and Tas2r108 1 0.04 0.33 0.1
171 INT237812 Esr1 Positive_regulation of Positive_regulation of soc 1 0.05 0.6 0.1
172 INT201747 Itpr3 Positive_regulation of Localization of Esr1 2 0.03 1.19 0.09
173 INT264085 CYP2C19 Regulation of CYP3A4 1 0.02 0 0.09
174 INT220394 MRXS5 Positive_regulation of Gene_expression of CYP19A1 1 0.00 0.89 0.09
175 INT308662 Binding of Esr1 and Fdft1 1 0.00 0.05 0.09
176 INT232559 Map3k1 Positive_regulation of Esr1 1 0.19 0.26 0.09
177 INT261396 Nsdhl Positive_regulation of Transcription of Esr1 1 0.02 2.1 0.09
178 INT341776 ESR1 Positive_regulation of Gene_expression of SLC6A3 1 0.06 0.08 0.09
179 INT177296 Binding of CXADR and CYP3A4 1 0.30 0 0.09
180 INT232557 Erbb2 Positive_regulation of Esr1 1 0.23 0.26 0.09
181 INT285070 CCL16 Positive_regulation of Gene_expression of CYP19A1 1 0.02 0.69 0.09
182 INT220412 Cpox Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.9 0.09
183 INT264102 Cyp1a2 Regulation of CYP3A4 1 0.03 0 0.09
184 INT264105 Cyp2e1 Regulation of CYP3A4 1 0.02 0 0.09
185 INT52836 ESR1 Positive_regulation of HSD17B7 1 0.43 0.41 0.09
186 INT99476 Binding of CYP3A4 and ABCB1 2 0.28 0 0.08
187 INT245642 Nr3c1 Regulation of Gene_expression of Hpse 1 0.05 1.33 0.08
188 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
189 INT192863 Binding of Ddit3 and Esr1 1 0.09 0.67 0.08
190 INT192860 Binding of Calr and Esr1 1 0.06 0.67 0.08
191 INT192865 Binding of Esr1 and Pdia3 1 0.07 0.67 0.08
192 INT192862 Binding of Esr1 and Hspa5 1 0.08 0.68 0.08
193 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
194 INT346136 ADM Positive_regulation of ICAM1 1 0.20 0.92 0.08
195 INT100127 ADM Positive_regulation of PRL 1 0.28 0.51 0.08
196 INT177265 Binding of CYP3A4 and NR1H4 1 0.03 0 0.08
197 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
198 INT199973 ESR1 Negative_regulation of EEF1B2P2 1 0.01 0.46 0.08
199 INT261262 AIS Negative_regulation of Cyp19a1 1 0.01 0.2 0.08
200 INT346147 ADM Positive_regulation of Gene_expression of VCAM1 1 0.19 0.91 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for androgen metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in androgen metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
2 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
3 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51
4 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
5 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
6 INT7787 Positive_regulation of Akr1d1 52 0.66 3.55 31.71
7 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27
8 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6
9 INT37296 Binding of Esr1 117 0.43 62.51 27.33
10 INT20462 Binding of ESR1 210 0.44 102.7 26.34
11 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
12 INT20575 Gene_expression of Akr1d1 48 0.57 6.2 22.5
13 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21
14 INT7920 Binding of Akr1d1 26 0.27 3.64 19.73
15 INT34569 Regulation of Akr1d1 26 0.24 3.06 18.37
16 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26
17 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
18 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45
19 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
20 INT92354 Localization of ESR1 77 0.75 33.04 15.51
21 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
22 INT11034 Negative_regulation of Akr1d1 23 0.18 3.43 14.84
23 INT2038 Localization of Esr1 104 0.79 40.12 13.27
24 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
25 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
26 INT10597 Gene_expression of Cyp19a1 27 0.78 7.48 9.11
27 INT20579 Transcription of Akr1d1 9 0.04 2.91 8.37
28 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34
29 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
30 INT63057 Regulation of CYP3A4 31 0.61 5.75 6.92
31 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
32 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
33 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25
34 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13
35 INT50572 Localization of Akr1d1 14 0.59 0.51 5.87
36 INT135760 Regulation of Gene_expression of Cyp19a1 2 0.62 1.15 5.81
37 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
38 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
39 INT52814 Negative_regulation of Nr3c1 9 0.57 5.69 5.41
40 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38
41 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37
42 INT78393 Gene_expression of Adm 16 0.78 8.4 4.92
43 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
44 INT26754 Positive_regulation of Positive_regulation of Akr1d1 8 0.05 0.28 4.75
45 INT114718 Positive_regulation of Gene_expression of CYP3A4 17 0.49 4.69 4.69
46 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
47 INT70756 Gene_expression of Adm 28 0.77 13.33 4.22
48 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
49 INT49712 Regulation of Nr3c1 10 0.28 5.65 4.06
50 INT158593 Negative_regulation of Negative_regulation of CYP3A4 5 0.43 1.16 4.01
51 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
52 INT20461 Binding of Esr1 34 0.48 9.58 3.66
53 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56
54 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
55 INT122511 Negative_regulation of Binding of Akr1d1 1 0.04 0.14 3.29
56 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
57 INT116376 Transcription of Cyp19a1 2 0.40 0.74 3.04
58 INT100785 Protein_catabolism of CYP3A4 7 1.00 0.76 3.01
59 INT133809 Negative_regulation of Gene_expression of CYP19A1 9 0.43 7.67 2.99
60 INT113277 Positive_regulation of Gene_expression of CYP19A1 13 0.69 10.23 2.97
61 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
62 INT76875 Positive_regulation of Adm 12 0.58 3.36 2.72
63 INT155216 Negative_regulation of Gene_expression of CYP3A4 9 0.56 3.81 2.71
64 INT174727 Positive_regulation of Positive_regulation of ESR1 14 0.44 6.3 2.7
65 INT77250 Positive_regulation of Gene_expression of Nr3c1 4 0.44 3.32 2.64
66 INT50571 Regulation of Gene_expression of Akr1d1 3 0.33 0.33 2.4
67 INT122709 Localization of CYP3A4 16 0.75 5.41 2.38
68 INT8484 Localization of Nr3c1 8 0.53 3.12 2.32
69 INT250727 Negative_regulation of ADM 3 0.38 8.32 2.26
70 INT71048 Transcription of CYP19A1 11 0.72 8.74 2.24
71 INT111113 Binding of CYP19A1 15 0.36 9.17 2.12
72 INT20578 Positive_regulation of Gene_expression of Akr1d1 5 0.22 0.26 2.1
73 INT99039 Negative_regulation of Gene_expression of Nr3c1 2 0.37 1.96 2.08
74 INT342803 Positive_regulation of Transcription of Cyp19a1 1 0.30 0.33 2.08
75 INT117898 Positive_regulation of Protein_catabolism of CYP3A4 1 0.67 0 2.08
76 INT149263 Regulation of Negative_regulation of CYP3A4 4 0.44 1 2.03
77 INT141968 Positive_regulation of ADM 12 0.65 11.19 2
78 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
79 INT81347 Regulation of Cyp19a1 7 0.40 2.1 1.94
80 INT135313 Regulation of Gene_expression of Nr3c1 3 0.39 3.44 1.94
81 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92
82 INT52305 Binding of Nr3c1 7 0.15 3.95 1.9
83 INT218959 Negative_regulation of Protein_catabolism of ESR1 3 0.37 0.97 1.9
84 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
85 INT102449 Binding of ADM 12 0.33 5.85 1.73
86 INT35937 Negative_regulation of Positive_regulation of Akr1d1 2 0.40 0 1.72
87 INT73616 Positive_regulation of Localization of Akr1d1 2 0.07 0 1.68
88 INT96971 Positive_regulation of Gene_expression of Esr1 6 0.46 2.27 1.67
89 INT10596 Positive_regulation of Cyp19a1 10 0.42 2.08 1.62
90 INT222089 Positive_regulation of Localization of Esr1 19 0.49 8.73 1.58
91 INT49448 Positive_regulation of Positive_regulation of Nr3c1 1 0.38 0 1.55
92 INT7578 Transcription of Nr3c1 5 0.32 0.43 1.47
93 INT61553 Positive_regulation of Regulation of Akr1d1 1 0.05 0 1.46
94 INT127889 Regulation of Gene_expression of CYP19A1 11 0.62 6.7 1.41
95 INT118988 Negative_regulation of Adm 3 0.10 1.05 1.41
96 INT102228 Localization of Adm 9 0.69 1.58 1.34
97 INT169743 Regulation of Positive_regulation of Adm 1 0.37 0.38 1.32
98 INT252389 Negative_regulation of Gene_expression of ADM 2 0.38 4.78 1.3
99 INT117897 Negative_regulation of Protein_catabolism of CYP3A4 1 0.55 0 1.28
100 INT8511 Localization of Esr1 6 0.80 3.27 1.26
101 INT48037 Regulation of Adm 8 0.44 3.96 1.24
102 INT128752 Negative_regulation of Localization of Esr1 11 0.43 4.8 1.23
103 INT141969 Positive_regulation of Gene_expression of ADM 4 0.57 4.07 1.2
104 INT824 Negative_regulation of Negative_regulation of ESR1 3 0.42 1.53 1.18
105 INT81757 Regulation of Gene_expression of Adm 6 0.44 2.86 1.16
106 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
107 INT20576 Negative_regulation of Gene_expression of Akr1d1 2 0.03 0.23 1.13
108 INT150838 Positive_regulation of Gene_expression of Adm 4 0.06 1.98 1.11
109 INT81945 Negative_regulation of Binding of Esr1 3 0.32 0.55 1.06
110 INT168395 Transcription of Cyp19a1 2 0.51 2.5 1.06
111 INT168397 Gene_expression of Cyp19a1 2 0.06 1.77 1.06
112 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
113 INT108347 Regulation of Adm 5 0.26 2.55 1.04
114 INT125541 Transcription of CYP3A4 7 0.69 2.14 1.02
115 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98
116 INT168398 Localization of Cyp19a1 1 0.08 0.89 0.97
117 INT154468 Negative_regulation of Transcription of ESR1 3 0.29 1.14 0.96
118 INT173747 Regulation of Positive_regulation of Esr1 4 0.37 4.85 0.95
119 INT82533 Regulation of Positive_regulation of Akr1d1 1 0.08 0 0.94
120 INT236576 Positive_regulation of Binding of Esr1 3 0.41 2.39 0.92
121 INT154465 Negative_regulation of Transcription of Esr1 1 0.05 0 0.92
122 INT225094 Localization of ADM 5 0.63 3.89 0.91
123 INT128755 Protein_catabolism of Esr1 10 0.57 4.61 0.9
124 INT248304 Positive_regulation of Localization of Nr3c1 2 0.10 1.39 0.87
125 INT118987 Localization of Adm 4 0.50 0.34 0.84
126 INT73914 Negative_regulation of Transcription of Esr1 3 0.39 0.75 0.84
127 INT174728 Positive_regulation of Transcription of ESR1 10 0.47 3.3 0.83
128 INT125092 Negative_regulation of Binding of ESR1 8 0.42 4.15 0.82
129 INT33818 Positive_regulation of Negative_regulation of Esr1 3 0.40 0.98 0.82
130 INT79344 Binding of Cyp19a1 4 0.33 0.61 0.8
131 INT54353 Regulation of Transcription of Akr1d1 1 0.03 0.08 0.74
132 INT161778 Regulation of Gene_expression of Esr1 13 0.51 9.46 0.73
133 INT92082 Regulation of Binding of ESR1 5 0.45 2.41 0.73
134 INT239494 Regulation of Localization of Esr1 4 0.19 1.15 0.72
135 INT161339 Localization of Cyp19a1 1 0.73 1.32 0.71
136 INT73917 Regulation of Transcription of Esr1 4 0.25 1.5 0.7
137 INT20577 Negative_regulation of Transcription of Akr1d1 1 0.02 0.23 0.66
138 INT191177 Regulation of Localization of ESR1 7 0.42 2.04 0.64
139 INT9836 Negative_regulation of Negative_regulation of Esr1 3 0.29 0.95 0.63
140 INT7576 Positive_regulation of Transcription of Nr3c1 1 0.19 0.3 0.62
141 INT116247 Positive_regulation of Localization of Adm 1 0.04 0.17 0.62
142 INT96323 Regulation of Transcription of Nr3c1 1 0.20 0 0.59
143 INT171105 Positive_regulation of Positive_regulation of CYP19A1 5 0.39 4.02 0.58
144 INT173748 Phosphorylation of Esr1 11 0.77 5.7 0.55
145 INT353896 Negative_regulation of Phosphorylation of Cyp19a1 1 0.22 0.47 0.55
146 INT353893 Phosphorylation of Cyp19a1 1 0.31 0.46 0.55
147 INT74101 Negative_regulation of Adm 3 0.06 1.2 0.53
148 INT173744 Positive_regulation of Positive_regulation of Esr1 10 0.43 7.05 0.52
149 INT346181 Regulation of Gene_expression of ADM 1 0.35 1.67 0.52
150 INT199410 Negative_regulation of Binding of CYP3A4 4 0.43 0.96 0.5
151 INT190899 Negative_regulation of Phosphorylation of ESR1 3 0.33 1.01 0.49
152 INT61552 Regulation of Binding of Akr1d1 1 0.06 0 0.49
153 INT137556 Negative_regulation of Cyp19a1 3 0.35 1.53 0.48
154 INT71046 Localization of CYP19A1 2 0.78 1.38 0.48
155 INT290850 Regulation of Positive_regulation of Nr3c1 1 0.12 0.75 0.47
156 INT240710 Positive_regulation of Regulation of Esr1 1 0.09 1.34 0.47
157 INT116387 Binding of Adm 6 0.47 1 0.46
158 INT206484 Localization of Shh 2 0.75 1.14 0.46
159 INT187717 Regulation of Negative_regulation of CYP19A1 11 0.42 2.85 0.45
160 INT127890 Positive_regulation of Negative_regulation of CYP19A1 6 0.50 1.41 0.45
161 INT135131 Regulation of Gene_expression of CYP3A4 8 0.59 4.32 0.44
162 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
163 INT71561 Positive_regulation of Gene_expression of Adm 4 0.61 2.67 0.43
164 INT52815 Regulation of Negative_regulation of Nr3c1 1 0.08 0.05 0.43
165 INT207726 Regulation of ADM 4 0.40 2.14 0.42
166 INT84915 Negative_regulation of Gene_expression of Cyp19a1 2 0.15 1.29 0.42
167 INT174725 Positive_regulation of Localization of ESR1 8 0.47 2.45 0.41
168 INT199409 Positive_regulation of Negative_regulation of CYP3A4 7 0.50 2.54 0.41
169 INT346173 Negative_regulation of Positive_regulation of ADM 1 0.38 1.02 0.39
170 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
171 INT268930 Regulation of Regulation of Esr1 2 0.41 0.48 0.38
172 INT284683 Binding of Hsd17b6 1 0.03 0.64 0.38
173 INT181122 Positive_regulation of Gene_expression of Cyp19a1 1 0.02 0.68 0.36
174 INT178630 Positive_regulation of Negative_regulation of ESR1 2 0.04 0.64 0.35
175 INT150839 Regulation of Gene_expression of Adm 1 0.04 0.89 0.35
176 INT34570 Regulation of Regulation of Akr1d1 1 0.01 0 0.35
177 INT236580 Regulation of Binding of Esr1 4 0.39 1.1 0.34
178 INT155222 Positive_regulation of Transcription of CYP3A4 2 0.50 0.13 0.34
179 INT176586 Positive_regulation of Binding of ESR1 11 0.41 4.64 0.33
180 INT209323 Positive_regulation of Transcription of CYP19A1 5 0.32 4.22 0.33
181 INT183916 Negative_regulation of Binding of Esr1 1 0.06 0.91 0.32
182 INT192845 Negative_regulation of Positive_regulation of Esr1 2 0.35 1.15 0.31
183 INT73915 Negative_regulation of Negative_regulation of Esr1 1 0.40 0.06 0.31
184 INT158581 Negative_regulation of Positive_regulation of CYP3A4 7 0.43 1.83 0.29
185 INT153772 Negative_regulation of Localization of ESR1 7 0.54 4.42 0.27
186 INT78997 Negative_regulation of AKR1C4 2 0.57 0.23 0.27
187 INT51857 Positive_regulation of Phosphorylation of Akr1d1 1 0.01 0 0.27
188 INT51854 Phosphorylation of Akr1d1 1 0.02 0 0.27
189 INT282487 Regulation of Negative_regulation of Cyp19a1 1 0.22 0.6 0.27
190 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
191 INT102450 Positive_regulation of Binding of ADM 1 0.29 0 0.24
192 INT122601 Transcription of Adm 1 0.29 0.73 0.24
193 INT122603 Positive_regulation of Transcription of Adm 1 0.26 0.74 0.24
194 INT150837 Positive_regulation of Regulation of Adm 1 0.06 0.64 0.23
195 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
196 INT96972 Positive_regulation of Binding of Esr1 4 0.22 1.35 0.21
197 INT102227 Protein_catabolism of Adm 1 0.30 0 0.21
198 INT90773 Binding of AKR1C4 2 0.36 0.52 0.2
199 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
200 INT186021 Positive_regulation of Positive_regulation of Esr1 1 0.08 0 0.19
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox