GO:0008228

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Name opsonization
Categary Process
Go Slim No
Go Link GO:0008228
Unique Molecular Interactions 154
Total Molecular Interactions 281
Total Single Events 3207
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for opsonization. They are ordered first by their pain relevance and then by number of times they were reported for opsonization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
2 INT253863 Binding of LBP and PNP 1 0.13 1.5 1.5
3 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
4 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
5 INT224410 Binding of CRP and CIMT 3 0.42 10.46 1.2
6 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
7 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
8 INT174910 Binding of LBP and IFIH1 1 0.04 1.01 1.01
9 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
10 INT261461 Positive_regulation of Akr1d1 Regulation of Sftpd 1 0.01 0 0.86
11 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83
12 INT261458 Akr1d1 Regulation of Sftpd 1 0.01 0 0.82
13 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
14 INT261447 Sftpd Positive_regulation of Akr1d1 1 0.01 0 0.77
15 INT240729 Binding of CRP and HLA-A 1 0.11 2.18 0.71
16 INT202037 Binding of CRP and URB1 1 0.01 1.26 0.68
17 INT255260 Binding of Cd47 and Tsp1 1 0.20 1.42 0.67
18 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
19 INT329589 Serpina5 Positive_regulation of PTX3 1 0.03 1.52 0.66
20 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
21 INT261457 Sftpd Positive_regulation of Vta1 1 0.10 0 0.63
22 INT327165 RETNLB Regulation of Gene_expression of CRP 1 0.01 2.25 0.59
23 INT316674 Binding of CRP and SFTPD 1 0.16 2.02 0.59
24 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56
25 INT243056 Binding of LBP and Tlr4 1 0.00 1.11 0.55
26 INT106744 Binding of CRP and EGFL7 2 0.07 2.35 0.51
27 INT329587 Binding of PTX3 and HEY1 1 0.00 2.03 0.5
28 INT184405 CRP Positive_regulation of Gene_expression of ASF1A 1 0.03 1.17 0.49
29 INT277063 CRP Positive_regulation of Gene_expression of MMP10 1 0.39 1.53 0.48
30 INT277065 CRP Positive_regulation of Gene_expression of MMP1 1 0.41 1.52 0.47
31 INT261450 Binding of Sftpd and Ptgdr 1 0.08 0.19 0.47
32 INT277064 CRP Positive_regulation of Gene_expression of TIMP1 1 0.15 1.47 0.45
33 INT261451 Sftpd Positive_regulation of Ptgdr 1 0.09 0.05 0.45
34 INT323702 HGF Regulation of Gene_expression of CRP 1 0.01 0.81 0.43
35 INT226070 Binding of CRP and MMP9 1 0.51 1.13 0.42
36 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41
37 INT326303 Binding of CRP and FKBP4 1 0.15 1.22 0.41
38 INT261464 Sftpd Regulation of Regulation of Ptgdr 1 0.08 0.07 0.41
39 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37
40 INT242025 Binding of CRP and CHDH 7 0.18 15.72 0.36
41 INT270789 CRP Negative_regulation of Gene_expression of TNF 1 0.34 0.87 0.36
42 INT277011 CRP Positive_regulation of Gene_expression of F3 1 0.06 1.03 0.32
43 INT238895 Binding of CRP and INS 1 0.00 0.93 0.32
44 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
45 INT194045 Binding of CRP and PM20D2 1 0.01 1.64 0.27
46 INT346196 AMELX Negative_regulation of CRP 1 0.04 0.36 0.26
47 INT300779 STAT3 Positive_regulation of CRP 1 0.41 0.62 0.26
48 INT300778 STAT3 Positive_regulation of Transcription of CRP 1 0.38 0.62 0.26
49 INT226073 Binding of CRP and SHBG 2 0.10 2.14 0.24
50 INT252356 Binding of THBS1 and Cd47 1 0.00 0.44 0.24
51 INT184404 CRP Regulation of Gene_expression of KRT20 1 0.02 1.21 0.24
52 INT194047 Negative_regulation of Binding of CRP and PM20D2 1 0.02 1.57 0.23
53 INT261455 Sftpd Regulation of Ptgdr 1 0.11 0.09 0.23
54 INT255261 Tsp1 Positive_regulation of Binding of Cd47 1 0.27 0.5 0.23
55 INT306333 Lbp Positive_regulation of Binding of Ly96 1 0.09 0.24 0.22
56 INT182816 EEF1A2 Negative_regulation of CRP 1 0.28 1.84 0.21
57 INT244015 Binding of Cd47 and Magt1 1 0.01 0.08 0.21
58 INT306328 Binding of Lbp and Tlr4 1 0.31 0.23 0.21
59 INT228703 MPO Regulation of Positive_regulation of CRP 1 0.40 1.63 0.2
60 INT264298 NOL3 Negative_regulation of CRP 1 0.39 0.49 0.2
61 INT175464 Hand2 Positive_regulation of Gene_expression of Sftpd 1 0.19 1.05 0.2
62 INT242037 Binding of CRP and SNRNP70 3 0.07 4.62 0.19
63 INT252330 Binding of Cd36 and Cd47 2 0.10 0.72 0.19
64 INT240625 Binding of CRP and Hdlcl1 1 0.01 2.56 0.19
65 INT139302 Binding of CRP and TLR4 1 0.38 1.18 0.19
66 INT261459 Sftpd Negative_regulation of Ldha 1 0.08 0.63 0.18
67 INT228984 CRP Positive_regulation of IL6 2 0.63 0.99 0.17
68 INT306326 Tlr4 Positive_regulation of Localization of Lbp 1 0.30 0.31 0.16
69 INT261460 Binding of Sftpd and Akr1d1 1 0.01 0.43 0.16
70 INT254392 Binding of CRP and GSN 1 0.12 0.33 0.16
71 INT306329 Lbp Regulation of Tlr4 1 0.29 0.32 0.16
72 INT279031 Binding of Sirpa and Cd47 1 0.09 0.77 0.15
73 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14
74 INT343836 Binding of IRF6 and LBP 1 0.02 0.8 0.14
75 INT140648 Binding of CRP and CCL11 1 0.14 0.88 0.13
76 INT261456 Sftpd Positive_regulation of Gene_expression of Th 1 0.10 0.77 0.13
77 INT266681 TRD@ Regulation of CRP 1 0.06 0.5 0.13
78 INT281267 Binding of CRP and TIMP1 1 0.06 0.82 0.13
79 INT323019 Binding of PTX3 and Crp 1 0.06 1.17 0.13
80 INT261448 Sftpd Positive_regulation of Phospho1 1 0.01 0.58 0.12
81 INT261449 Sftpd Positive_regulation of Gene_expression of Phospho1 1 0.01 0.58 0.12
82 INT255514 Binding of CRP and LAIR1 1 0.06 0 0.12
83 INT185162 Binding of CRP and Retn 1 0.13 2.8 0.12
84 INT175463 Sftpd Negative_regulation of Gene_expression of Hand2 1 0.17 0.96 0.11
85 INT229287 BAS Negative_regulation of CRP 1 0.04 0.36 0.11
86 INT281042 Serping1 Regulation of MBL2 1 0.01 0.74 0.11
87 INT192358 CRP Regulation of Positive_regulation of HSPD1 1 0.15 2.46 0.1
88 INT192353 CRP Regulation of CP 1 0.20 2.46 0.1
89 INT306452 Binding of MBL2 and TLR4 1 0.38 0.37 0.1
90 INT279409 Binding of CRP and IGKV2-19 1 0.02 0.4 0.1
91 INT223482 CRP Positive_regulation of GOPC 1 0.08 0.8 0.1
92 INT271343 Binding of CRP and PAPPA 1 0.20 0.86 0.1
93 INT306453 MBL2 Regulation of Binding of TLR4 1 0.48 0.37 0.1
94 INT192352 CRP Regulation of HSPD1 1 0.15 2.46 0.1
95 INT10739 IL3 Positive_regulation of CRP 1 0.18 1.14 0.09
96 INT285423 LBP Positive_regulation of Gene_expression of IRF6 1 0.07 0.19 0.09
97 INT294711 CRP Regulation of CCL2 1 0.12 0 0.09
98 INT294712 CRP Regulation of IL6 1 0.41 0 0.09
99 INT61824 Binding of SERPINH1 and CRP 1 0.24 0.63 0.08
100 INT271354 MPO Regulation of Gene_expression of CRP 1 0.16 1.74 0.08
101 INT271351 MPO Positive_regulation of CRP 1 0.07 1.69 0.08
102 INT299493 IL6 Positive_regulation of CRP 1 0.55 0.16 0.08
103 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
104 INT337572 TREM1 Regulation of CRP 1 0.05 0.99 0.07
105 INT332305 Binding of CRP and Ccl2 1 0.15 0.86 0.06
106 INT213261 TNF Positive_regulation of CRP 1 0.24 1.59 0.06
107 INT255512 Binding of COL5A2 and CRP 1 0.01 0 0.06
108 INT279406 Binding of CRP and MTRF1 1 0.02 0.23 0.05
109 INT306006 Binding of CD14 and LBP 1 0.06 0.63 0.04
110 INT170668 GOPC Regulation of CRP 1 0.07 0.32 0.04
111 INT240623 Binding of CRP and Apob 1 0.01 0.52 0.04
112 INT279536 Binding of C1QC and CRP 1 0.01 0.59 0.04
113 INT279531 Binding of LPA and MBL2 1 0.02 0.54 0.04
114 INT319120 CRP Positive_regulation of Gene_expression of SERPINE1 1 0.70 0.54 0.04
115 INT313508 Binding of ALOX12 and CRP 1 0.06 0.44 0.03
116 INT278291 Binding of CRP and DBP 1 0.12 1.57 0.03
117 INT262994 Binding of CRP and HSD11B1 1 0.15 3.02 0.03
118 INT278290 Binding of CRP and PADI4 1 0.11 1.2 0.03
119 INT192354 Binding of CRP and HSPD1 1 0.12 1.28 0
120 INT218260 Binding of CRP and HIST2H4A 1 0.03 1.93 0
121 INT97562 Sftpd Regulation of Gene_expression of Fos 1 0.13 0 0
122 INT308583 Binding of CRP and PLA2G7 1 0.28 1.23 0
123 INT265951 Clas4 Negative_regulation of CRP 1 0.01 0.57 0
124 INT353910 Binding of CRP and UROD 1 0.06 0.34 0
125 INT242034 Positive_regulation of Binding of CRP and CHDH 1 0.18 2.08 0
126 INT192356 Binding of CP and CRP 1 0.16 4.35 0
127 INT339708 MBL2 Regulation of MAP3K2 1 0.00 0.1 0
128 INT313499 Binding of ALOX5AP and CRP 1 0.07 0.45 0
129 INT218259 Binding of CRP and SEPT5 1 0.04 0.33 0
130 INT242022 Negative_regulation of Binding of CRP and CIMT 1 0.33 1.01 0
131 INT97563 Sftpd Positive_regulation of Gene_expression of Fos 1 0.22 0 0
132 INT279535 Binding of C1QC and MBL2 1 0.01 2.79 0
133 INT279530 MBL2 Positive_regulation of Positive_regulation of C3 1 0.26 1.71 0
134 INT242040 Negative_regulation of CRP Regulation of CHDH 1 0.17 0.58 0
135 INT97561 Sftpd Regulation of Fos 1 0.13 0 0
136 INT265952 Clas4 Regulation of Negative_regulation of CRP 1 0.01 0.57 0
137 INT242024 CRP Regulation of CIMT 1 0.24 0.44 0
138 INT279539 Binding of CFD and MBL2 1 0.09 0.08 0
139 INT242032 Binding of CRP and RS1 1 0.01 1.92 0
140 INT285427 LBP Positive_regulation of Localization of IL8 1 0.10 0.19 0
141 INT291623 Binding of CRP and CSTA 1 0.03 0.38 0
142 INT339704 MBL2 Regulation of SGK2 1 0.06 0.1 0
143 INT155552 Binding of FANCB and LBP 1 0.39 0.06 0
144 INT242036 CRP Regulation of CHDH 1 0.18 1.57 0
145 INT218258 Binding of CRP and HIST1H1B 1 0.05 0.61 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for opsonization. They are ordered first by their pain relevance and then by number of times they were reported in opsonization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03
2 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74
3 INT9664 Binding of LBP 127 0.48 94.9 63.42
4 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33
5 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23
6 INT78251 Positive_regulation of LBP 38 0.69 39.98 26.73
7 INT100861 Binding of CRP 179 0.48 175.2 26.45
8 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9
9 INT9088 Negative_regulation of LBP 48 0.58 33.06 25.89
10 INT23257 Regulation of CRP 127 0.62 100.05 21.87
11 INT106745 Localization of CRP 65 0.81 66.44 15.21
12 INT57000 Localization of LBP 21 0.78 11.01 10.01
13 INT32624 Regulation of LBP 15 0.60 11.48 8.71
14 INT73234 Positive_regulation of Lbp 13 0.69 12.55 8.57
15 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58
16 INT135319 Positive_regulation of Positive_regulation of CRP 20 0.50 26.45 5.61
17 INT139803 Gene_expression of PTX3 22 0.75 26.21 5.07
18 INT11106 Gene_expression of Lbp 10 0.67 10.29 4.52
19 INT104221 Regulation of Gene_expression of CRP 30 0.45 20.01 4.07
20 INT11107 Binding of Lbp 12 0.42 4.42 3.41
21 INT175449 Gene_expression of Sftpd 30 0.55 25.7 3.15
22 INT139805 Positive_regulation of PTX3 15 0.70 14.84 2.71
23 INT204124 Transcription of CRP 14 0.69 20.79 2.71
24 INT175458 Positive_regulation of Gene_expression of Sftpd 1 0.49 17.86 2.36
25 INT228889 Protein_catabolism of LBP 4 0.77 5.14 2.13
26 INT97558 Gene_expression of Sftpd 6 0.47 3.35 2.07
27 INT166311 Positive_regulation of Gene_expression of LBP 7 0.49 4.15 1.81
28 INT203541 Regulation of Binding of LBP 1 0.39 1.96 1.79
29 INT162636 Localization of PTX3 8 0.78 9.73 1.77
30 INT35242 Negative_regulation of MBL2 17 0.48 12.53 1.73
31 INT323018 Regulation of PTX3 1 0.27 6.86 1.59
32 INT247102 Binding of MBL2 16 0.38 14.18 1.54
33 INT279572 Gene_expression of MBL2 27 0.64 20.88 1.51
34 INT279019 Gene_expression of Cd47 3 0.56 1.43 1.31
35 INT171576 Phosphorylation of CRP 6 0.80 5.55 1.22
36 INT139804 Binding of PTX3 6 0.48 7.42 1.21
37 INT175462 Positive_regulation of Sftpd 1 0.49 6.62 1.04
38 INT261436 Binding of Sftpd 1 0.29 0.18 1.02
39 INT158064 Negative_regulation of Gene_expression of LBP 1 0.41 1.54 0.97
40 INT341431 Regulation of Positive_regulation of LBP 1 0.24 1.14 0.96
41 INT160599 Regulation of Gene_expression of LBP 2 0.44 1.23 0.92
42 INT252313 Positive_regulation of Cd47 4 0.22 3.95 0.87
43 INT220161 Negative_regulation of Binding of LBP 2 0.43 1.35 0.87
44 INT351306 Positive_regulation of Localization of LBP 1 0.47 1.82 0.82
45 INT154792 Regulation of Regulation of LBP 1 0.26 0.5 0.81
46 INT154793 Regulation of Localization of LBP 1 0.44 0.5 0.81
47 INT162635 Positive_regulation of Localization of PTX3 2 0.49 4.86 0.78
48 INT184415 Regulation of Positive_regulation of CRP 3 0.43 4.32 0.77
49 INT329588 Positive_regulation of Regulation of PTX3 1 0.47 1.85 0.74
50 INT279202 Positive_regulation of Localization of CRP 3 0.69 2.45 0.72
51 INT288907 Negative_regulation of Gene_expression of PTX3 1 0.41 1.15 0.63
52 INT204123 Positive_regulation of Transcription of CRP 5 0.49 8.11 0.57
53 INT270790 Negative_regulation of Binding of CRP 5 0.42 2.9 0.55
54 INT231736 Regulation of Transcription of CRP 1 0.45 1.46 0.54
55 INT281033 Regulation of MBL2 6 0.34 4.96 0.52
56 INT204119 Negative_regulation of Transcription of CRP 2 0.36 2.57 0.52
57 INT243960 Binding of Cd47 2 0.18 1.06 0.51
58 INT300578 Negative_regulation of Cd47 1 0.24 0.17 0.44
59 INT288903 Positive_regulation of Gene_expression of PTX3 2 0.67 1.47 0.43
60 INT300586 Negative_regulation of Gene_expression of Cd47 1 0.33 0.25 0.43
61 INT350630 Negative_regulation of Gene_expression of Cd47 1 0.20 0.8 0.37
62 INT161608 Negative_regulation of PTX3 2 0.32 1.36 0.36
63 INT350627 Gene_expression of Cd47 1 0.28 0.79 0.36
64 INT175456 Regulation of Gene_expression of Sftpd 1 0.32 1.92 0.34
65 INT306469 Negative_regulation of Gene_expression of MBL2 1 0.40 1.72 0.29
66 INT300582 Regulation of Gene_expression of Cd47 1 0.25 0.13 0.28
67 INT135025 Regulation of Gene_expression of Lbp 1 0.44 2.22 0.28
68 INT265901 Regulation of Localization of CRP 1 0.30 2 0.27
69 INT242028 Negative_regulation of Negative_regulation of CRP 3 0.43 2.39 0.24
70 INT194049 Positive_regulation of Binding of CRP 3 0.48 4.48 0.24
71 INT188242 Negative_regulation of Positive_regulation of CRP 4 0.23 3.94 0.22
72 INT261438 Negative_regulation of Sftpd 1 0.30 0.1 0.21
73 INT306468 Positive_regulation of Gene_expression of MBL2 7 0.47 4.3 0.17
74 INT306317 Localization of Lbp 1 0.53 0.31 0.16
75 INT306309 Positive_regulation of Localization of Lbp 1 0.33 0.32 0.16
76 INT329446 Positive_regulation of Phosphorylation of CRP 1 0.29 0.44 0.16
77 INT175453 Binding of Sftpd 2 0.23 2.04 0.15
78 INT355774 Negative_regulation of Regulation of CRP 1 0.15 0.64 0.15
79 INT240125 Positive_regulation of Negative_regulation of CRP 2 0.37 1.04 0.14
80 INT175445 Transcription of Sftpd 1 0.51 1.78 0.12
81 INT341341 Regulation of Gene_expression of MBL2 1 0.18 0.58 0.1
82 INT322065 Localization of MBL2 1 0.56 1.34 0.1
83 INT153771 Negative_regulation of Localization of CRP 3 0.38 0.99 0.09
84 INT279580 Positive_regulation of Binding of MBL2 4 0.48 2.15 0.08
85 INT220332 Transcription of LBP 2 0.50 2.2 0.08
86 INT135023 Negative_regulation of Positive_regulation of Lbp 1 0.29 0.97 0.08
87 INT220337 Negative_regulation of Negative_regulation of LBP 1 0.35 0.35 0.08
88 INT135021 Regulation of Positive_regulation of Lbp 1 0.31 0.98 0.08
89 INT335179 Negative_regulation of Sftpd 1 0.21 2.61 0.06
90 INT261445 Regulation of Sftpd 1 0.10 0.69 0.05
91 INT322696 Localization of Sftpd 1 0.09 0.62 0.05
92 INT306467 Transcription of MBL2 1 0.44 0.7 0.05
93 INT135030 Regulation of Lbp 2 0.45 0.63 0.04
94 INT174491 Positive_regulation of Regulation of CRP 2 0.22 0.9 0.04
95 INT322697 Positive_regulation of Gene_expression of Sftpd 1 0.07 1.22 0.04
96 INT323016 Positive_regulation of Positive_regulation of PTX3 1 0.45 1.41 0.04
97 INT336900 Positive_regulation of Sftpd 1 0.01 1.39 0.03
98 INT175446 Negative_regulation of Positive_regulation of Sftpd 1 0.26 0.43 0.03
99 INT351620 Protein_catabolism of CRP 1 0.88 0 0.03
100 INT351621 Negative_regulation of Protein_catabolism of CRP 1 0.38 0 0.03
101 INT306473 Negative_regulation of Binding of MBL2 1 0.36 0.07 0.03
102 INT279576 Positive_regulation of MBL2 4 0.38 4.1 0
103 INT137124 Negative_regulation of Lbp 2 0.37 0 0
104 INT323017 Regulation of Gene_expression of PTX3 1 0.44 4.31 0
105 INT134805 Positive_regulation of Positive_regulation of LBP 1 0.45 0.15 0
106 INT97559 Negative_regulation of Gene_expression of Sftpd 1 0.28 0 0
107 INT242027 Regulation of Regulation of CRP 1 0.27 0 0
108 INT175441 Positive_regulation of Positive_regulation of Sftpd 1 0.33 0.31 0
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