GO:0008235

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Name metalloexopeptidase activity
Categary Function
Go Slim No
Go Link GO:0008235
Unique Molecular Interactions 28
Total Molecular Interactions 39
Total Single Events 93
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for metalloexopeptidase activity. They are ordered first by their pain relevance and then by number of times they were reported for metalloexopeptidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT255317 Binding of Dpep1 and Nav1 1 0.01 0 2.42
2 INT255318 Binding of Dpep1 and Nrcam 1 0.00 0 2.16
3 INT14626 Binding of Dpep1 and Pax3 1 0.01 0 0.87
4 INT255324 Negative_regulation of Binding of Dpep1 and 2E 1 0.02 0 0.73
5 INT255325 Binding of Dpep1 and 2E 1 0.02 0 0.73
6 INT163946 Binding of ERAP1 and Il23r 1 0.23 0.56 0.72
7 INT160711 Binding of KIR3DL1 and ERAP1 1 0.15 0.71 0.71
8 INT255319 Binding of Dpep1 and Kcnq2 1 0.01 0 0.6
9 INT255320 Binding of Dpep1 and Kcnq3 1 0.01 0 0.6
10 INT255326 Binding of Dpep1 and AIS 1 0.00 0 0.6
11 INT224724 Gm2458 Negative_regulation of Metap2 1 0.02 1.57 0.57
12 INT348177 Binding of HLA-B and ERAP1 1 0.14 0.92 0.49
13 INT14062 Binding of POMC and RNPEP 1 0.01 0 0.33
14 INT255322 Binding of Dpep1 and Csnk2b 1 0.01 0 0.29
15 INT255316 Csnk2b Regulation of Binding of Dpep1 1 0.01 0 0.22
16 INT220243 IL1RN Negative_regulation of Gene_expression of DPEP1 1 0.20 0.22 0.19
17 INT318306 Binding of DPEP1 and NLRP3 1 0.03 1.77 0.15
18 INT54095 ERAP1 Regulation of Protein_catabolism of Fgg 1 0.00 0 0.09
19 INT220244 IL1B Regulation of Gene_expression of DPEP1 1 0.17 0 0.08
20 INT220241 IL1RN Regulation of Gene_expression of DPEP1 1 0.24 0 0.08
21 INT220238 IL1RN Regulation of Protein_catabolism of DPEP1 1 0.14 0 0.08
22 INT220247 IL1B Regulation of Protein_catabolism of DPEP1 1 0.10 0 0.08
23 INT270835 Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1 1 0.04 0.08 0.07
24 INT342358 Binding of Irs1 and Erap1 1 0.37 0 0
25 INT342367 Binding of Erap1 and OSBPL1A 1 0.39 0 0
26 INT159710 Binding of Tap1 and ERAP1 1 0.04 0.11 0
27 INT152402 Binding of Il1a and ERAP1 1 0.00 0.06 0
28 INT307418 Binding of Cybb and Metap2 1 0.01 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for metalloexopeptidase activity. They are ordered first by their pain relevance and then by number of times they were reported in metalloexopeptidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT224723 Negative_regulation of Metap2 1 0.33 11.14 3.76
2 INT14625 Binding of Dpep1 2 0.02 0 3.36
3 INT159709 Binding of ERAP1 12 0.47 3.42 2.91
4 INT161121 Binding of Erap1 2 0.48 1.99 1.99
5 INT176609 Gene_expression of Dpep1 8 0.03 2.37 1.07
6 INT220249 Gene_expression of DPEP1 1 0.40 0.99 0.95
7 INT255304 Regulation of Binding of Dpep1 1 0.02 0 0.95
8 INT46483 Localization of Dpep1 4 0.06 1.58 0.88
9 INT45645 Negative_regulation of Erap1 2 0.11 0.07 0.77
10 INT145747 Regulation of ERAP1 1 0.25 0.19 0.76
11 INT14063 Gene_expression of RNPEP 1 0.04 0 0.66
12 INT255306 Positive_regulation of Dpep1 1 0.02 0 0.61
13 INT154643 Negative_regulation of ERAP1 1 0.11 0.69 0.58
14 INT255308 Negative_regulation of Binding of Dpep1 1 0.02 0 0.46
15 INT220254 Positive_regulation of Gene_expression of DPEP1 1 0.22 0.56 0.44
16 INT36120 Positive_regulation of RNPEP 1 0.25 0 0.33
17 INT227514 Regulation of Dpep1 1 0.02 0.06 0.3
18 INT62619 Positive_regulation of Negative_regulation of Erap1 1 0.05 0 0.27
19 INT69801 Positive_regulation of DPEP1 3 0.49 0.89 0.23
20 INT220251 Regulation of DPEP1 1 0.12 0.33 0.15
21 INT342327 Positive_regulation of Erap1 1 0.43 1.1 0.13
22 INT220259 Protein_catabolism of DPEP1 1 0.34 0 0.11
23 INT69802 Binding of DPEP1 1 0.02 0 0.09
24 INT220263 Negative_regulation of DPEP1 1 0.22 0.28 0.09
25 INT4418 Positive_regulation of ERAP1 4 0.45 1.21 0.08
26 INT224720 Binding of Metap2 1 0.20 0.38 0.07
27 INT270815 Localization of DPEP1 1 0.06 0.08 0.07
28 INT270819 Positive_regulation of Localization of DPEP1 1 0.04 0.08 0.07
29 INT220258 Negative_regulation of Gene_expression of DPEP1 1 0.22 0 0.03
30 INT159707 Gene_expression of ERAP1 4 0.66 0.69 0
31 INT342328 Regulation of Erap1 1 0.25 0 0
32 INT163945 Positive_regulation of Gene_expression of ERAP1 1 0.26 0.09 0
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