GO:0008253

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Name 5'-nucleotidase activity
Categary Function
Go Slim No
Go Link GO:0008253
Unique Molecular Interactions 46
Total Molecular Interactions 87
Total Single Events 391
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for 5'-nucleotidase activity. They are ordered first by their pain relevance and then by number of times they were reported for 5'-nucleotidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT283426 Binding of Lcn2 and Nt5e 1 0.08 5.8 1.24
2 INT164722 Avp Regulation of NT5C 1 0.06 0.88 1.15
3 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07
4 INT287132 Binding of NT5E and Comt 1 0.03 0.11 0.73
5 INT164721 Binding of NT5C and Acot1 1 0.04 0.45 0.65
6 INT164723 Binding of Avp and NT5C 1 0.07 0.45 0.65
7 INT150965 NT5C2 Positive_regulation of PRKG1 1 0.04 0.07 0.62
8 INT311256 Nt5e Positive_regulation of Positive_regulation of Adora1 1 0.49 0.19 0.54
9 INT287131 Negative_regulation of Binding of NT5E and Comt 1 0.03 0.06 0.23
10 INT283429 Nt5e Regulation of Gene_expression of Cxcr1 1 0.00 0.22 0.2
11 INT21576 NT5C3 Negative_regulation of Gene_expression of TIMP1 1 0.03 0.25 0.2
12 INT21578 NT5C3 Regulation of Gene_expression of IL4I1 1 0.01 0.24 0.19
13 INT299725 AFP Positive_regulation of Positive_regulation of ACPP 1 0.00 0.78 0.17
14 INT283428 Negative_regulation of Binding of Lcn2 and Nt5e 1 0.06 1.09 0.15
15 INT311255 Binding of Gpi1 and Nt5e 1 0.05 0.16 0.13
16 INT48595 NT5C3 Positive_regulation of CA2 1 0.01 0 0.13
17 INT48594 NT5C3 Positive_regulation of NA 1 0.00 0 0.13
18 INT287130 Positive_regulation of Binding of NT5E and Comt 1 0.04 0 0.12
19 INT62775 Regulation of Binding of NT5E and OPRK1 1 0.03 0 0.1
20 INT62776 Binding of NT5E and OPRK1 1 0.02 0 0.1
21 INT283427 Lcn2 Positive_regulation of Nt5e 1 0.08 0.21 0.09
22 INT283425 Lcn2 Positive_regulation of Gene_expression of Nt5e 1 0.07 0.13 0.07
23 INT283433 Nt5e Positive_regulation of Localization of IL8 1 0.01 0.21 0.07
24 INT225730 Car2 Positive_regulation of Entpd3 1 0.01 0.06 0.04
25 INT228285 Binding of Ptprc and Nt5e 1 0.06 0.25 0
26 INT228286 Binding of Cd14 and Nt5e 1 0.20 0.25 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for 5'-nucleotidase activity. They are ordered first by their pain relevance and then by number of times they were reported in 5'-nucleotidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT19391 Gene_expression of Nt5e 44 0.72 13.99 5.14
2 INT62784 Gene_expression of NT5E 46 0.65 15.95 3.72
3 INT89026 Positive_regulation of Nt5e 12 0.49 7.25 2.67
4 INT57115 Negative_regulation of NT5E 8 0.57 4.35 2.03
5 INT48035 Positive_regulation of NT5C2 5 0.67 2.42 1.91
6 INT48596 Positive_regulation of NT5C3 3 0.45 0.53 1.79
7 INT222031 Localization of Nt5e 16 0.75 3.1 1.73
8 INT241733 Negative_regulation of Nt5e 4 0.40 2.84 1.58
9 INT164720 Positive_regulation of Localization of NT5C 1 0.06 0.87 1.39
10 INT96420 Positive_regulation of NT5E 9 0.49 3.7 1.38
11 INT155036 Localization of NT5E 6 0.73 4.1 1.35
12 INT341885 Positive_regulation of Localization of NT5C3 1 0.49 0.41 1.07
13 INT231528 Localization of NT5C3 2 0.73 1.78 1.06
14 INT283402 Binding of Nt5e 10 0.30 2.53 0.85
15 INT287128 Protein_catabolism of NT5E 2 0.11 0.64 0.76
16 INT225744 Gene_expression of Entpd3 1 0.13 0.82 0.75
17 INT294133 Regulation of Gene_expression of NT5E 4 0.12 1.36 0.71
18 INT164717 Localization of NT5C 1 0.09 0.43 0.69
19 INT150966 Positive_regulation of Positive_regulation of NT5C2 1 0.49 0.07 0.63
20 INT25162 Positive_regulation of ACPP 7 0.41 4.51 0.62
21 INT164718 Regulation of NT5C 3 0.19 1.36 0.62
22 INT247550 Positive_regulation of Gene_expression of Nt5e 5 0.56 3.21 0.61
23 INT155035 Binding of NT5E 3 0.36 1.78 0.61
24 INT164719 Regulation of Regulation of NT5C 1 0.03 0.44 0.58
25 INT251661 Phosphorylation of NT5E 2 0.21 1.59 0.46
26 INT96419 Positive_regulation of Gene_expression of NT5E 3 0.49 1.46 0.41
27 INT206749 Gene_expression of ACPP 4 0.40 2.61 0.37
28 INT287129 Regulation of NT5E 3 0.12 1.02 0.32
29 INT37869 Regulation of ACPP 3 0.34 3.03 0.31
30 INT354743 Gene_expression of NT5C 1 0.20 1.72 0.25
31 INT283403 Phosphorylation of Nt5e 2 0.67 0.23 0.21
32 INT294138 Positive_regulation of Localization of NT5E 1 0.14 0.41 0.21
33 INT294141 Regulation of Localization of NT5E 1 0.12 0.42 0.21
34 INT283404 Positive_regulation of Phosphorylation of Nt5e 1 0.07 0.23 0.21
35 INT247566 Transcription of Nt5e 3 0.17 1.73 0.19
36 INT21580 Negative_regulation of NT5C3 1 0.04 0.23 0.19
37 INT163493 Localization of ACPP 2 0.41 1.8 0.11
38 INT62762 Negative_regulation of ACPP 1 0.01 0.51 0.09
39 INT247554 Negative_regulation of Negative_regulation of Nt5e 1 0.10 1.85 0.08
40 INT354744 Binding of NT5C 1 0.10 0.29 0.08
41 INT247552 Regulation of Nt5e 1 0.05 2.07 0.07
42 INT283401 Positive_regulation of Binding of Nt5e 1 0.06 0.41 0.04
43 INT172322 Negative_regulation of Gene_expression of Nt5e 1 0.41 1.03 0.04
44 INT283409 Positive_regulation of Transcription of Nt5e 1 0.07 0.06 0.03
45 INT283405 Positive_regulation of Localization of Nt5e 1 0.07 0 0
46 INT311251 Protein_catabolism of Nt5e 1 0.53 0 0
47 INT283398 Negative_regulation of Binding of Nt5e 1 0.05 0.46 0
48 INT303640 Gene_expression of NT5C3 1 0.07 0.73 0
49 INT329193 Regulation of Binding of NT5E 1 0.07 0.67 0
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