GO:0008270

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Name zinc ion binding
Categary Function
Go Slim No
Go Link GO:0008270
Unique Molecular Interactions 6437
Total Molecular Interactions 8405
Total Single Events 74727
Pain Genes Associated 716

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for zinc ion binding. They are ordered first by their pain relevance and then by number of times they were reported for zinc ion binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6
2 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
3 INT269444 Binding of RAB5A and HHIP 1 0.04 0 5.79
4 INT51497 Cck Negative_regulation of Localization of Trim13 1 0.34 0 4.53
5 INT32444 Binding of Cpe and Pomc 2 0.22 0 4.47
6 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06
7 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
8 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
9 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
10 INT73071 Binding of Cpe and Insrr 3 0.01 0.33 3.38
11 INT215943 Binding of Mmp14 and Timp2 1 0.21 1.59 3.33
12 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29
13 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23
14 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
15 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19
16 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
17 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
18 INT94204 NCOR2 Regulation of Gene_expression of SP5 1 0.02 2.15 3.12
19 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
20 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08
21 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
22 INT123451 Binding of YY1 and Adra2a 1 0.37 0 2.98
23 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
24 INT42728 Binding of PRLR and Cpe 1 0.00 0 2.91
25 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
26 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
27 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
28 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
29 INT91350 Binding of Pla2g4a and RYBP 1 0.00 1.15 2.65
30 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
31 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
32 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
33 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54
34 INT170038 Gtf3a Regulation of Gene_expression of DRGX 1 0.00 1.36 2.46
35 INT231968 Binding of Cpn1 and Rvm 1 0.11 1.57 2.45
36 INT231970 Binding of Cpn1 and Pag1 1 0.07 1.56 2.44
37 INT135867 Zfp821 Positive_regulation of Positive_regulation of Chrne 1 0.01 0 2.44
38 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
39 INT255317 Binding of Dpep1 and Nav1 1 0.01 0 2.42
40 INT56726 Cpe Negative_regulation of Pomc 1 0.07 0 2.41
41 INT153728 RYBP Positive_regulation of Gpt 3 0.03 2.01 2.36
42 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
43 INT231971 Binding of Cpn1 and Shbdp1 1 0.04 1.39 2.26
44 INT231967 Binding of Psmd1 and Cpn1 1 0.06 1.39 2.25
45 INT231969 Binding of Cfp and Cpn1 1 0.05 1.38 2.25
46 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
47 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
48 INT255318 Binding of Dpep1 and Nrcam 1 0.00 0 2.16
49 INT39108 Binding of PDYN and YY1 2 0.50 0.44 2.14
50 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13
51 INT45376 Binding of Cpe and Mme 1 0.07 0.32 2.13
52 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13
53 INT66157 Binding of ALB and BDP1 1 0.11 0 2.13
54 INT135868 Zfp821 Positive_regulation of Binding of ACAA1 1 0.00 0 2.11
55 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
56 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06
57 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
58 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
59 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
60 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
61 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
62 INT53751 Positive_regulation of Cyp2e1 Positive_regulation of RYBP 1 0.14 0.89 1.98
63 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
64 INT69556 Slc7a11 Regulation of Cpe 2 0.06 0.46 1.95
65 INT73072 Negative_regulation of Binding of Cpe and Insrr 1 0.00 0 1.94
66 INT60867 Binding of G2e3 and Gpm6a 2 0.01 0.1 1.93
67 INT68272 Binding of Oprd1 and G2e3 1 0.00 0.11 1.93
68 INT227493 Binding of TCEA1 and SIRT2 1 0.01 1.55 1.93
69 INT116815 Binding of Pias1 and Ppbp 1 0.36 0.86 1.92
70 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
71 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
72 INT129903 Nr1i2 Regulation of Cyp3a11 1 0.64 1.26 1.9
73 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
74 INT243043 Binding of Mmp9 and Timp1 1 0.05 0.25 1.86
75 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
76 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82
77 INT119917 Zfp821 Positive_regulation of Positive_regulation of Oprd1 1 0.01 0 1.82
78 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
79 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
80 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
81 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
82 INT167320 Binding of CPE and OPRM1 1 0.14 0.63 1.77
83 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
84 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
85 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73
86 INT92369 Binding of CYP2D6 and RYBP 1 0.25 0.15 1.73
87 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
88 INT282398 Binding of Mefv and Nlrp3 1 0.40 6.8 1.72
89 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
90 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71
91 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71
92 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
93 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
94 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
95 INT62065 Binding of YY1 and Penk 3 0.14 0 1.69
96 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67
97 INT61675 Binding of Gpm6a and Man2a2 1 0.00 0.08 1.67
98 INT276672 Binding of Prkcg and Nav1 1 0.16 0.18 1.67
99 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
100 INT276680 Binding of Prkcg and Nkx1-1 1 0.05 0.18 1.66
101 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
102 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
103 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66
104 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
105 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65
106 INT119918 Zfp821 Positive_regulation of Binding of ACAA1 1 0.00 0 1.64
107 INT45816 Binding of Car2 and Gabrg1 2 0.28 0.15 1.63
108 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
109 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
110 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
111 INT107965 Binding of HLA-B and Mefv 2 0.34 3.91 1.61
112 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
113 INT32937 Binding of Pgrmc1 and Dtnb 1 0.20 0 1.61
114 INT167200 Gtf3a Regulation of Gene_expression of Ngf 1 0.08 1.47 1.6
115 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
116 INT342993 PHEX Regulation of Protein_catabolism of SFTPA1 1 0.00 2.84 1.58
117 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 1 0.27 0.56 1.58
118 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
119 INT168611 Binding of Mmp9 and Ndor1 1 0.29 0.41 1.57
120 INT26985 Cpe Negative_regulation of Localization of Ins1 1 0.02 0 1.57
121 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
122 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
123 INT130839 Gfap Positive_regulation of S100B 1 0.51 1.9 1.56
124 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56
125 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
126 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55
127 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
128 INT276671 Prkcg Positive_regulation of Nav1 1 0.23 0.21 1.55
129 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
130 INT100784 RYBP Positive_regulation of CYP3A4 1 0.44 0 1.54
131 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54
132 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53
133 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
134 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
135 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
136 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
137 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
138 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5
139 INT166676 Binding of PRKCA and UGT1A6 1 0.30 0 1.5
140 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49
141 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
142 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
143 INT44504 Mt1a Positive_regulation of Prl 1 0.37 0 1.48
144 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
145 INT30042 Binding of YY1 and Gnrhr 1 0.18 0 1.47
146 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
147 INT161865 Mors1 Positive_regulation of Prkcg 1 0.00 0.12 1.47
148 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
149 INT150392 Binding of MEFV and PSTPIP1 2 0.51 10.49 1.44
150 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
151 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
152 INT111760 Dio1 Positive_regulation of Binding of Cpe 1 0.04 0.34 1.44
153 INT111761 Positive_regulation of Binding of Cpe and Insrr 1 0.01 0.33 1.43
154 INT111756 Dio1 Positive_regulation of Cpe 1 0.04 0.34 1.42
155 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
156 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
157 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
158 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
159 INT43814 Binding of Cpe and Oprm1 1 0.08 0 1.41
160 INT154114 PENK Positive_regulation of YY1 1 0.50 0.06 1.41
161 INT154113 POMC Positive_regulation of YY1 1 0.70 0.06 1.41
162 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
163 INT79745 Gtf3a Positive_regulation of Positive_regulation of Sst 1 0.09 0 1.4
164 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
165 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
166 INT162105 Nr4a3 Regulation of ACPT-I 1 0.10 0.26 1.38
167 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
168 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
169 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
170 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
171 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
172 INT54490 Npepo Positive_regulation of Gene_expression of Pdyn 1 0.06 0 1.35
173 INT140532 Gtf3a Positive_regulation of DYT10 1 0.12 1.83 1.34
174 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
175 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
176 INT131888 gr Positive_regulation of Gene_expression of Prkcg 1 0.00 0 1.32
177 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32
178 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
179 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
180 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
181 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
182 INT27425 Mtr Positive_regulation of Gene_expression of Il1f5 1 0.06 0 1.3
183 INT18659 Plat Regulation of ZC3H12D 1 0.02 0.1 1.29
184 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
185 INT121802 DEAF1 Negative_regulation of HTR1A 1 0.46 0.88 1.29
186 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
187 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
188 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
189 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
190 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
191 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
192 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
193 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
194 INT73398 Binding of Pnoc and Nr1d2 1 0.10 0 1.27
195 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
196 INT124099 Binding of GGT5 and RYBP 1 0.00 0.34 1.26
197 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
198 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
199 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
200 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25

Single Events

The table below shows the top 100 pain related interactions that have been reported for zinc ion binding. They are ordered first by their pain relevance and then by number of times they were reported in zinc ion binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
2 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
3 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64
4 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
5 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
6 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
7 INT4822 Localization of Ca2 417 0.80 99.57 96.45
8 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35
9 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
10 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
11 INT6437 Binding of YY1 154 0.47 26.3 90.46
12 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
13 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
14 INT22967 Positive_regulation of RYBP 94 0.56 37.04 85.92
15 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71
16 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
17 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
18 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
19 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
20 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
21 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16
22 INT8962 Gene_expression of Cpe 110 0.71 39.67 71.67
23 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
24 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
25 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
26 INT7134 Localization of KNG1 127 0.79 65.73 67.97
27 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
28 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01
29 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
30 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
31 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89
32 INT546 Binding of ALB 311 0.48 85.98 60.14
33 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16
34 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74
35 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
36 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72
37 INT18883 Negative_regulation of RYBP 53 0.56 21.14 57.52
38 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01
39 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
40 INT1486 Negative_regulation of Cpe 85 0.59 28.78 54.08
41 INT48642 Positive_regulation of TCEA1 92 0.70 24.59 53.64
42 INT1032 Regulation of Ca2 202 0.52 54.91 53.03
43 INT1487 Regulation of Cpe 68 0.62 10.24 52.91
44 INT122041 Binding of Ppara 308 0.48 189.17 51.48
45 INT5957 Positive_regulation of Cpe 65 0.69 21.07 51.22
46 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47
47 INT117598 Regulation of ACR 118 0.26 41.25 48.01
48 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
49 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06
50 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9
51 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76
52 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49
53 INT4656 Localization of RYBP 49 0.77 5.28 46.21
54 INT20492 Gene_expression of MMP12 89 0.76 81.36 46.12
55 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97
56 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
57 INT17561 Localization of Car2 303 0.79 60.95 44.52
58 INT5214 Localization of Cpe 49 0.73 13.3 44.36
59 INT935 Localization of Gtf3a 124 0.70 35.72 43.3
60 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02
61 INT613 Gene_expression of Alb 268 0.78 149.84 42.78
62 INT11180 Binding of RYBP 52 0.46 13.86 42.53
63 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
64 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78
65 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74
66 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
67 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75
68 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
69 INT163134 Gene_expression of ACR 78 0.65 30.39 38.48
70 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37
71 INT18774 Gene_expression of RYBP 67 0.65 47.66 37.59
72 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
73 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
74 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49
75 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45
76 INT12029 Gene_expression of Car1 143 0.67 29.69 36.39
77 INT64436 Gene_expression of P2rx1 93 0.78 32.69 36.12
78 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
79 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
80 INT103094 Binding of PPARA 308 0.47 177.26 34.75
81 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
82 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67
83 INT12161 Positive_regulation of P2rx2 70 0.69 34.22 34.4
84 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
85 INT223416 Gene_expression of Trhde 2 0.48 64.16 34.21
86 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05
87 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
88 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81
89 INT2699 Binding of Cpe 40 0.48 7.07 33.64
90 INT5489 Localization of CA2 172 0.80 39.46 33.56
91 INT234 Binding of Alb 151 0.48 52.34 32.97
92 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9
93 INT99610 Localization of MMP9 126 0.79 48.46 32.67
94 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
95 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
96 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23
97 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
98 INT70776 Positive_regulation of P2rx1 62 0.62 32.55 30.75
99 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46
100 INT2229 Positive_regulation of Man2a2 50 0.69 7.47 30.33
101 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06
102 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
103 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65
104 INT18489 Binding of Man2a2 59 0.48 11.27 29.38
105 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
106 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
107 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
108 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43
109 INT3076 Regulation of KNG1 52 0.60 20.39 27.89
110 INT6717 Negative_regulation of YY1 45 0.57 15.35 27.8
111 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71
112 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
113 INT37296 Binding of Esr1 117 0.43 62.51 27.33
114 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
115 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98
116 INT3167 Binding of KNG1 48 0.48 23.26 26.77
117 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7
118 INT5232 Negative_regulation of Enpep 56 0.57 3.25 26.7
119 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67
120 INT111081 Gene_expression of CA1 19 0.75 51.09 26.64
121 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
122 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4
123 INT20462 Binding of ESR1 210 0.44 102.7 26.34
124 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
125 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68
126 INT140193 Gene_expression of Mmp3 58 0.71 49.65 25.4
127 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
128 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03
129 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
130 INT93717 Gene_expression of Mmp3 85 0.78 33.95 24.89
131 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
132 INT6385 Regulation of Man2a2 48 0.61 7.8 24.68
133 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
134 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06
135 INT16431 Localization of Lnpep 62 0.70 6.28 23.94
136 INT34487 Localization of MMP2 56 0.81 31.41 23.61
137 INT13145 Positive_regulation of Car1 60 0.70 16.32 23.23
138 INT18884 Regulation of RYBP 25 0.38 11.43 23.2
139 INT87607 Positive_regulation of Prkcc 25 0.69 6.06 22.78
140 INT310853 Positive_regulation of Gene_expression of Trhde 1 0.43 42.95 22.75
141 INT17962 Regulation of Car2 124 0.41 33.98 22.71
142 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
143 INT7678 Localization of Alb 142 0.81 80.93 22.49
144 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
145 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19
146 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86
147 INT7573 Positive_regulation of Nr3c2 38 0.67 20 21.84
148 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
149 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72
150 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6
151 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
152 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
153 INT170313 Gene_expression of Mmp1a 50 0.65 38.53 21.36
154 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31
155 INT112427 Positive_regulation of P2rx4 27 0.68 26.29 21.31
156 INT43226 Gene_expression of Hivep3 75 0.71 30.53 21.14
157 INT117527 Binding of Prkca 25 0.48 6.43 21.05
158 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
159 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
160 INT5096 Positive_regulation of Gtf3a 79 0.60 42.26 20.62
161 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
162 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41
163 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18
164 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09
165 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86
166 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
167 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
168 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4
169 INT12031 Negative_regulation of Car1 44 0.59 20.46 19.36
170 INT3359 Regulation of YY1 32 0.60 8.19 19.2
171 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
172 INT14546 Positive_regulation of Localization of Ca2 93 0.67 31.09 18.72
173 INT16110 Positive_regulation of ZC3H12D 30 0.46 6.27 18.72
174 INT7474 Gene_expression of Man2a2 38 0.67 3.31 18.42
175 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35
176 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08
177 INT23635 Positive_regulation of MMP12 31 0.59 28.19 17.95
178 INT132997 Localization of Mmp9 59 0.80 45.9 17.61
179 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53
180 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
181 INT8037 Negative_regulation of Man2a2 39 0.42 5.15 17.44
182 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
183 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1
184 INT49379 Localization of MMP12 26 0.77 13.07 16.93
185 INT65211 Binding of Prkcg 38 0.48 14.75 16.92
186 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
187 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
188 INT258328 Gene_expression of Aicda 76 0.71 58.29 16.86
189 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
190 INT197375 Gene_expression of Car1 84 0.65 16.46 16.45
191 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43
192 INT99898 Gene_expression of Mmp14 37 0.56 28.54 16.39
193 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26
194 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18
195 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17
196 INT1261 Localization of Adh1 63 0.81 19.36 16.09
197 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98
198 INT13400 Negative_regulation of Enpep 30 0.50 4.23 15.86
199 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
200 INT79458 Localization of Prkca 30 0.81 11.13 15.78
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