GO:0008285

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Name negative regulation of cell proliferation
Categary Process
Go Slim No
Go Link GO:0008285
Unique Molecular Interactions 8694
Total Molecular Interactions 12109
Total Single Events 94353
Pain Genes Associated 412

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cell proliferation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of cell proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
2 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
3 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
4 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
5 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
6 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
7 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
8 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
9 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
10 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
11 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
12 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
13 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
14 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
15 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
16 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18
17 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16
18 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
19 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
20 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
21 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
22 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63
23 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
24 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
25 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
26 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
27 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
28 INT215943 Binding of Mmp14 and Timp2 1 0.21 1.59 3.33
29 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
30 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
31 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
32 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08
33 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
34 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
35 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
36 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
37 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
38 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
39 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
40 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
41 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
42 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
43 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
44 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
45 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
46 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
47 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
48 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
49 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
50 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
51 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
52 INT67905 Binding of Spn and Fosl1 1 0.24 2.1 2.54
53 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
54 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
55 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
56 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
57 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
58 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
59 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
60 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
61 INT88730 Binding of OPRM1 and Mop3 1 0.00 0 2.34
62 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 0.00 0.08 2.31
63 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
64 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
65 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
66 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
67 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
68 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2
69 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
70 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
71 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
72 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
73 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
74 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
75 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
76 INT1315 Pomc Positive_regulation of Localization of Gnrhr 3 0.38 0.16 2.16
77 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13
78 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
79 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
80 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
81 INT51198 Positive_regulation of Binding of OPRM1 and PDYN 2 0.18 0.3 2.08
82 INT51199 Binding of OPRM1 and PDYN 2 0.13 0.3 2.08
83 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
84 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
85 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
86 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
87 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01
88 INT35502 Ghrh Positive_regulation of Localization of Gnrhr 7 0.57 0.18 2
89 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
90 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
91 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
92 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
93 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
94 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
95 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
96 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
97 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
98 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94
99 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
100 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
101 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
102 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
103 INT113572 Binding of DMRT1 and OPRM1 1 0.01 0 1.9
104 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
105 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
106 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
107 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
108 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
109 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
110 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
111 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
112 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
113 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
114 INT167319 Binding of OPRM1 and PCSK2 1 0.22 0.63 1.77
115 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
116 INT167320 Binding of CPE and OPRM1 1 0.14 0.63 1.77
117 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
118 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
119 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
120 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
121 INT157524 Binding of GRM5 and OPRM1 1 0.36 0 1.74
122 INT57249 GNRH1 Regulation of Regulation of CGA 1 0.20 0 1.74
123 INT37840 Binding of Cyp27b1 and Oprd1 1 0.01 0 1.73
124 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
125 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
126 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
127 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
128 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
129 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
130 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
131 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
132 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
133 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
134 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66
135 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
136 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
137 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
138 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
139 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
140 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65
141 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
142 INT134742 Binding of OPRM1 and SV2A 1 0.33 0.18 1.64
143 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64
144 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
145 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
146 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
147 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
148 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
149 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
150 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
151 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
152 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
153 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
154 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
155 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
156 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
157 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
158 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
159 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
160 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
161 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
162 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
163 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
164 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
165 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
166 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
167 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
168 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
169 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
170 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
171 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
172 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
173 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
174 INT260897 CRH Positive_regulation of Localization of IL8 1 0.24 0.09 1.51
175 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
176 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
177 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
178 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
179 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5
180 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
181 INT64628 Binding of Oxt and Gal 2 0.29 0.29 1.49
182 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49
183 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
184 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
185 INT14375 Gal Positive_regulation of Localization of Prl 1 0.77 0 1.48
186 INT155497 Oprk1 Negative_regulation of Tenc1 1 0.08 0.34 1.48
187 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
188 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
189 INT30042 Binding of YY1 and Gnrhr 1 0.18 0 1.47
190 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
191 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
192 INT165450 Gal Regulation of Ceacam3 1 0.41 0.06 1.47
193 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
194 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
195 INT141676 OPRM1 Positive_regulation of Ltp 1 0.04 0 1.46
196 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
197 INT141675 OPRM1 Positive_regulation of Negative_regulation of Ltp 1 0.04 0 1.46
198 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
199 INT12691 SST Negative_regulation of Localization of POMC 3 0.24 1.24 1.45
200 INT1314 Pomc Regulation of Localization of Gnrhr 2 0.16 0.14 1.45

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cell proliferation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of cell proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
3 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
5 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
6 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36
7 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
8 INT6852 Localization of TNF 883 0.81 705.95 270.84
9 INT10832 Gene_expression of IL8 1050 0.78 698.72 270
10 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
11 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
12 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
13 INT6481 Binding of TNF 624 0.48 510.2 214.82
14 INT767 Localization of Gnrhr 565 0.80 106.68 214.57
15 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
16 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
17 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
18 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
19 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28
20 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
21 INT9660 Regulation of TNF 363 0.62 312.94 139.99
22 INT4658 Binding of OPRM1 188 0.48 25.96 136.24
23 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
24 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
25 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
26 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
27 INT7395 Localization of GNRH1 399 0.81 62.88 117.68
28 INT12339 Localization of IL8 437 0.81 251.87 117.39
29 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
30 INT12082 Localization of IL6 365 0.81 241.78 105.78
31 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
32 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62
33 INT397 Localization of SST 232 0.81 58.05 101.19
34 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
35 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
36 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37
37 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
38 INT10166 Localization of Tnf 237 0.81 153.95 88.64
39 INT8650 Gene_expression of Gal 152 0.78 61.97 81.72
40 INT1309 Positive_regulation of Localization of Gnrhr 152 0.69 24.25 81.56
41 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57
42 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64
43 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
44 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
45 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
46 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
47 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
48 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
49 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
50 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
51 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34
52 INT6849 Localization of IL1B 229 0.81 112.56 69.63
53 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
54 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
55 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
56 INT19511 Localization of Il6 212 0.81 118.17 67.67
57 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
58 INT8347 Gene_expression of SST 181 0.78 104.59 65.45
59 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
60 INT11937 Localization of Il6 228 0.81 139.83 64.39
61 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
62 INT10706 Regulation of Il6 150 0.62 93.23 62.34
63 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
64 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
65 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
66 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
67 INT770 Regulation of Localization of Gnrhr 127 0.61 17.91 58.23
68 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
69 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
70 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
71 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66
72 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
73 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
74 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
75 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
76 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
77 INT69484 Positive_regulation of Gene_expression of OPRM1 75 0.70 12.86 52.27
78 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
79 INT5118 Regulation of SST 97 0.62 34.35 51.74
80 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
81 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
82 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
83 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
84 INT9210 Regulation of IL6 166 0.62 125.61 49.95
85 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
86 INT51163 Gene_expression of Gal 119 0.78 67.48 49.23
87 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
88 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
89 INT1564 Localization of OPRM1 41 0.80 8.03 44.67
90 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
91 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
92 INT13354 Transcription of TNF 108 0.72 85.81 42.32
93 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08
94 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97
95 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
96 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56
97 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
98 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
99 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
100 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
101 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
102 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46
103 INT11854 Gene_expression of Il1rl1 57 0.77 30.19 38.25
104 INT43507 Gene_expression of Gabbr1 79 0.78 28.53 38.22
105 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
106 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
107 INT5039 Positive_regulation of Gal 67 0.68 27.97 37.36
108 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2
109 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
110 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
111 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
112 INT77407 Regulation of Gene_expression of OPRM1 51 0.62 12.58 35.75
113 INT13501 Binding of Drd2 65 0.48 23.76 35.6
114 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54
115 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
116 INT6484 Binding of IL1B 122 0.47 75.84 35.07
117 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93
118 INT692 Negative_regulation of SST 72 0.59 28.68 34.52
119 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
120 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
121 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
122 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03
123 INT5868 Positive_regulation of GNRH1 122 0.69 20.96 32.8
124 INT691 Binding of SST 67 0.48 24.66 32.67
125 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
126 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
127 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
128 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17
129 INT9655 Regulation of Il6 98 0.62 70.92 31.95
130 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
131 INT35406 Localization of Tnf 94 0.81 64.63 31.65
132 INT9347 Localization of Il1b 58 0.81 26.13 31.53
133 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
134 INT47764 Binding of Jun 106 0.48 22.62 31.39
135 INT7396 Regulation of Localization of GNRH1 81 0.62 6.57 31.31
136 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
137 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
138 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
139 INT1158 Regulation of Agt 106 0.61 29.4 30.29
140 INT69483 Transcription of OPRM1 45 0.72 7.31 30.22
141 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21
142 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
143 INT7397 Negative_regulation of Localization of GNRH1 86 0.59 15.45 29.78
144 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
145 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
146 INT7412 Positive_regulation of SST 71 0.70 24.44 29.48
147 INT86437 Binding of IL6 154 0.48 121.22 29.3
148 INT49431 Phosphorylation of OPRM1 31 0.82 2.2 29.09
149 INT4868 Gene_expression of GAL 75 0.78 22.23 29.02
150 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
151 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
152 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81
153 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
154 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71
155 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51
156 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
157 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
158 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
159 INT5966 Localization of Il1a 50 0.78 22.91 26.54
160 INT3559 Negative_regulation of Localization of Gnrhr 73 0.58 18.89 26.41
161 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
162 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
163 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85
164 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
165 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
166 INT7394 Positive_regulation of Localization of GNRH1 67 0.69 7.22 25.29
167 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
168 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
169 INT5199 Gene_expression of Fosl1 44 0.78 8.66 24.8
170 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
171 INT12484 Binding of Drd2 45 0.48 15.17 24.72
172 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71
173 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
174 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
175 INT10835 Regulation of IL8 79 0.49 53.04 24.14
176 INT8518 Localization of Ifng 53 0.81 36.68 24.13
177 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
178 INT5131 Gene_expression of GNRH1 109 0.78 28.79 23.94
179 INT63419 Gene_expression of PTGES 109 0.77 40.83 23.67
180 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
181 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54
182 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
183 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
184 INT48081 Localization of Il1b 46 0.80 21.59 22.4
185 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
186 INT7715 Regulation of Drd2 35 0.62 10.79 22.3
187 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24
188 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
189 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
190 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
191 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
192 INT693 Negative_regulation of Localization of SST 46 0.59 8.57 21.75
193 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
194 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
195 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
196 INT5040 Regulation of Gal 42 0.60 12.72 21.18
197 INT117527 Binding of Prkca 25 0.48 6.43 21.05
198 INT97798 Localization of IRF6 86 0.73 33.27 20.94
199 INT52106 Negative_regulation of Localization of IL8 57 0.52 22.81 20.8
200 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
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