GO:0008305

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Name integrin complex
Categary Component
Go Slim No
Go Link GO:0008305
Unique Molecular Interactions 210
Total Molecular Interactions 318
Total Single Events 2263
Pain Genes Associated 28

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for integrin complex. They are ordered first by their pain relevance and then by number of times they were reported for integrin complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT81708 POMC Regulation of Gene_expression of ITGAM 1 0.53 0.72 3.1
2 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
3 INT107268 Binding of ITGAL and NCR3 1 0.01 2.76 2.07
4 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
5 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
6 INT81709 POMC Regulation of Gene_expression of ITGB2 1 0.40 0.34 1.57
7 INT81719 POMC Regulation of Gene_expression of ITGAL 1 0.35 0.34 1.57
8 INT81715 POMC Regulation of ITGB2 1 0.40 0.34 1.55
9 INT81721 POMC Regulation of ITGAM 1 0.39 0.34 1.55
10 INT81714 POMC Regulation of ITGAL 1 0.15 0.34 1.54
11 INT107265 Binding of HLA-DRB1 and ITGAL 1 0.01 1.41 1.1
12 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
13 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
14 INT272984 Il6 Positive_regulation of Gene_expression of Itgam 1 0.24 0.78 0.96
15 INT48381 CSF2 Positive_regulation of ITGAM 2 0.30 0.38 0.95
16 INT81716 ITGAL Regulation of ITGB2 2 0.30 1.24 0.78
17 INT81717 ITGAL Regulation of Gene_expression of ITGAM 1 0.30 0.17 0.78
18 INT81718 ITGAL Regulation of Gene_expression of FCGR3B 1 0.28 0.17 0.78
19 INT81711 ITGAL Regulation of Gene_expression of ITGB2 1 0.30 0.17 0.78
20 INT113546 Binding of FN1 and ITGA3 1 0.03 2.12 0.77
21 INT81713 ITGAL Regulation of ITGAM 1 0.30 0.17 0.77
22 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75
23 INT48386 CSF2 Positive_regulation of Positive_regulation of ITGAM 1 0.16 0.24 0.7
24 INT48385 CSF2 Regulation of Gene_expression of ITGAM 2 0.16 0.29 0.68
25 INT28080 POMC Negative_regulation of Gene_expression of ITGAM 1 0.00 0.16 0.65
26 INT265651 Binding of ITGAL and MYCN 1 0.00 0.46 0.62
27 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57
28 INT266376 Binding of Ager and Itgam 1 0.00 2.31 0.54
29 INT167194 FPR1 Positive_regulation of Gene_expression of ITGAM 1 0.52 0.8 0.53
30 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51
31 INT48382 CSF2 Positive_regulation of Gene_expression of ITGAM 1 0.23 0.25 0.49
32 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
33 INT71178 Binding of ITGB2 and Icam1 1 0.45 1.2 0.47
34 INT187099 Binding of Cd4 and Itga1 1 0.00 1.09 0.46
35 INT102691 RETNLB Positive_regulation of ITGAL 1 0.01 0.45 0.45
36 INT48388 CSF3 Regulation of Gene_expression of ITGAM 1 0.35 0.2 0.44
37 INT48383 CSF2 Regulation of Gene_expression of ITGB2 1 0.11 0.2 0.44
38 INT48389 CSF3 Regulation of Gene_expression of ITGB2 1 0.25 0.2 0.44
39 INT51829 Binding of ITGA2B and ANGPTL5 1 0.35 1.08 0.4
40 INT113551 Binding of ITGA3 and VTN 1 0.02 1.03 0.38
41 INT161009 Binding of Cpe and Itgam 1 0.03 0.53 0.37
42 INT161006 Itgam Regulation of Cpb2 1 0.07 0.52 0.37
43 INT161003 Binding of Itgam and Cpb2 1 0.10 0.52 0.37
44 INT161001 Itgam Regulation of Gfap 1 0.13 0.52 0.37
45 INT161002 Binding of Itgam and St13 1 0.11 0.52 0.37
46 INT161008 Itgam Regulation of St13 1 0.08 0.52 0.37
47 INT96158 Itgax Regulation of Gene_expression of H2-D1 1 0.14 0.09 0.35
48 INT206608 Binding of Ecm1 and Itgb5 1 0.02 0.41 0.33
49 INT61266 Nfkb1 Regulation of Gene_expression of Itgam 1 0.23 0.65 0.32
50 INT174658 TNF Positive_regulation of Gene_expression of ITGAM 1 0.16 1.54 0.3
51 INT170128 Binding of ITGAL and ITGB2 2 0.04 1.6 0.28
52 INT164636 Negative_regulation of CSF2 Positive_regulation of ITGAM 1 0.26 0.14 0.25
53 INT210798 Ihh Positive_regulation of Itgbl1 1 0.34 0 0.23
54 INT63420 F2 Positive_regulation of Gene_expression of ITGA2B 1 0.14 0.45 0.23
55 INT210785 Cdkn1c Positive_regulation of Itgbl1 1 0.38 0 0.23
56 INT210794 Timp4 Positive_regulation of Itgbl1 1 0.40 0 0.23
57 INT20403 FPR1 Positive_regulation of Itgax 1 0.02 0.22 0.22
58 INT224454 TNF Positive_regulation of Gene_expression of Itgam 1 0.27 0.35 0.22
59 INT224445 Il1 Positive_regulation of Gene_expression of Itgam 1 0.21 0.35 0.22
60 INT336946 Binding of ITGA4 and VCAM1 1 0.03 2.02 0.21
61 INT125153 IL1B Regulation of ITGB2 1 0.22 0.1 0.2
62 INT236362 Binding of Gfap and Itgam 1 0.23 2.31 0.2
63 INT125154 IL1B Regulation of Gene_expression of ITGB2 1 0.50 0.1 0.2
64 INT125155 IL1B Regulation of ITGAM 1 0.49 0.1 0.2
65 INT51830 Positive_regulation of Binding of ITGA2B and ANGPTL5 1 0.51 0.57 0.2
66 INT51828 Negative_regulation of Binding of ITGA2B and ANGPTL5 1 0.31 0.51 0.2
67 INT125156 IL1B Regulation of Gene_expression of ITGAM 1 0.49 0.1 0.2
68 INT93648 Adp Positive_regulation of ITGA2B 1 0.00 0.79 0.2
69 INT303979 Lep Positive_regulation of ITGB2 1 0.11 0.35 0.2
70 INT182151 ITGAX Positive_regulation of Binding of IFNA1 1 0.05 0.46 0.18
71 INT99013 Binding of Itgb2 and Selp 1 0.16 1.36 0.18
72 INT99006 Regulation of Binding of Selp and Itga1 1 0.06 1.36 0.18
73 INT99012 Binding of Selp and Itga1 1 0.05 1.36 0.18
74 INT182157 ITGAX Positive_regulation of IFNA1 1 0.05 0.46 0.18
75 INT99011 Regulation of Binding of Itgb2 and Selp 1 0.19 1.37 0.18
76 INT182155 DCPS Positive_regulation of Positive_regulation of ITGAX 1 0.04 0.46 0.18
77 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
78 INT314534 Ptger2 Regulation of Gene_expression of Itgam 1 0.02 1 0.17
79 INT277791 Binding of Icam1 and Itgal 1 0.03 0.37 0.17
80 INT67158 Binding of ITGA4 and Vcam1 1 0.00 0.2 0.17
81 INT101725 Binding of ITGA4 and Chrna7 1 0.00 0 0.16
82 INT210782 Ihh Negative_regulation of Itgbl1 1 0.31 0 0.16
83 INT273714 Positive_regulation of Binding of Icam1 and Itgb2 1 0.17 1.46 0.15
84 INT281302 Binding of Itgam and Fgg 1 0.00 0.62 0.15
85 INT304169 Il33 Positive_regulation of Gene_expression of Itgam 1 0.02 1.18 0.15
86 INT273717 Binding of Icam1 and Itgb2 1 0.17 1.45 0.15
87 INT128903 Binding of RNASE2 and Itga7 1 0.00 0.08 0.15
88 INT281315 Binding of Gp1bb and Itgam 1 0.00 0.62 0.15
89 INT58187 ITGA1 Positive_regulation of Itga3 1 0.01 1.47 0.14
90 INT327879 Binding of Itgb1 and Postn 1 0.02 1.05 0.14
91 INT327877 Itgb1 Negative_regulation of Gene_expression of Dlk1 1 0.02 0.99 0.13
92 INT173406 Binding of ITGAL and Itgb2 1 0.02 0.41 0.13
93 INT171792 GPER Regulation of Gene_expression of Itga2 1 0.00 0.54 0.12
94 INT271525 ITGB1 Positive_regulation of Gopc 1 0.02 0.57 0.11
95 INT266373 Itgam Positive_regulation of Ager 1 0.01 0.84 0.1
96 INT119454 Regulation of Binding of Itga2b and Gtf3a 1 0.00 0.14 0.1
97 INT119455 Binding of Itga2b and Gtf3a 1 0.00 0.14 0.1
98 INT236318 IGKV2D-38 Positive_regulation of ITGAM 1 0.01 0.13 0.1
99 INT119456 Binding of Itga2b and Fgg 1 0.00 0.14 0.1
100 INT232652 Binding of CD2 and ITGAL 1 0.03 0.28 0.09
101 INT279400 GANAB Regulation of ITGAL 1 0.01 0.75 0.09
102 INT67157 Negative_regulation of Binding of ITGA4 and Vcam1 1 0.00 0.1 0.09
103 INT253300 Itgam Positive_regulation of Gene_expression of Ptprc 1 0.19 0.11 0.09
104 INT216708 Binding of ITGA2B and SELP 1 0.35 0.36 0.09
105 INT216710 Positive_regulation of Binding of ITGA2B and SELP 1 0.48 0.36 0.09
106 INT173371 GPER Regulation of ITGAL 1 0.01 0.23 0.08
107 INT273649 Binding of Vcam1 and Itga1 1 0.01 0.4 0.08
108 INT303999 Lep Positive_regulation of Gene_expression of ITGA2 1 0.06 0.29 0.08
109 INT173376 GPER Regulation of ITGAX 1 0.00 0.23 0.08
110 INT303970 Lep Positive_regulation of Gene_expression of Itga2 1 0.09 0.29 0.08
111 INT267137 ICAM1 Regulation of ITGAL 2 0.12 0.57 0.07
112 INT284501 Positive_regulation of Binding of ICAM1 and ITGAL 1 0.06 0.2 0.07
113 INT231676 Binding of CD47 and ITGA5 1 0.02 0.08 0.07
114 INT284503 Binding of ICAM1 and ITGAM 1 0.05 0.2 0.07
115 INT278441 Lbp Positive_regulation of Gene_expression of ITGAX 1 0.44 1.18 0.07
116 INT20404 Negative_regulation of FPR1 Positive_regulation of Itgax 1 0.02 0.07 0.07
117 INT61386 Binding of ITGA2 and Fgg 1 0.00 0.06 0.06
118 INT89430 Binding of ICAM4 and ITGA4 1 0.05 0.48 0.06
119 INT284504 ITGAL Positive_regulation of Gene_expression of ITGAM 1 0.03 0.2 0.06
120 INT61387 Binding of ITGA2 and Vwf 1 0.01 0.06 0.06
121 INT317416 Binding of FN1 and ITGB1 1 0.47 0.69 0.05
122 INT216712 Binding of ITGA2B and PSMG1 1 0.09 0.18 0.05
123 INT284564 Binding of Itgax and Mthfd1 1 0.08 0.09 0.05
124 INT216706 Positive_regulation of Binding of ITGA2B and PSMG1 1 0.12 0.18 0.05
125 INT254390 Binding of FCGR2A and Itgam 1 0.24 0.63 0.04
126 INT260811 Binding of ITGA4 and ITGAL 1 0.02 0 0.03
127 INT273719 Binding of Itgb2 and Trav6-3 1 0.07 0.47 0.03
128 INT170121 ITGAL Regulation of CD44 1 0.07 1.07 0
129 INT331089 Binding of Cd3e and Itga2 1 0.09 0.2 0
130 INT236306 IGKV2D-38 Regulation of ITGAM 1 0.02 0.5 0
131 INT314537 Il10 Positive_regulation of Gene_expression of Itgam 1 0.21 1.23 0
132 INT335705 Binding of ITGA4 and Calr 1 0.01 0.43 0
133 INT32195 Itga7 Negative_regulation of Mbp 1 0.04 0.32 0
134 INT281314 Positive_regulation of Stx2 Positive_regulation of Gene_expression of Itgam 1 0.08 0.21 0
135 INT233267 Hoxa10 Regulation of Itgb3 1 0.15 0.14 0
136 INT170119 PECAM1 Regulation of Positive_regulation of ITGAL 1 0.01 1.07 0
137 INT170124 ITGAM Regulation of ITGB2 1 0.04 1.07 0
138 INT314971 Binding of ITGAX and Lbr 1 0.05 0.07 0
139 INT162508 Binding of ITGA2B and ITPR1 1 0.02 0.05 0
140 INT315069 ITGB4 Regulation of MT1X 1 0.27 0.52 0
141 INT170120 PECAM1 Regulation of ITGAM 1 0.00 1.07 0
142 INT79649 RIMS3 Regulation of Positive_regulation of ITGAL 1 0.00 0 0
143 INT170123 ITGAL Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0
144 INT331088 Binding of Itga2 and Klrb1c 1 0.11 0.2 0
145 INT344229 Itgam Regulation of Transcription of Tlr4 1 0.03 0.06 0
146 INT70320 Negative_regulation of B4GALNT1 Negative_regulation of Positive_regulation of ITGB2 1 0.03 0 0
147 INT301095 Binding of ITGAL and CHDH 1 0.00 0.71 0
148 INT344220 Itgam Regulation of Transcription of Tlr2 1 0.03 0.06 0
149 INT170125 ITGAM Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0
150 INT165438 PTAFR Positive_regulation of Gene_expression of ITGAM 1 0.45 0 0
151 INT170126 PECAM1 Regulation of ITGB2 1 0.01 1.07 0
152 INT170116 ITGAM Regulation of CD44 1 0.07 1.07 0
153 INT273720 Binding of Cd28 and Itgb2 1 0.10 0 0
154 INT315071 ITGB4 Regulation of Gene_expression of PAR4 1 0.35 0.53 0
155 INT191933 Itgam Positive_regulation of Cpox 1 0.07 0.36 0
156 INT233270 Meis1 Regulation of Gene_expression of Itgb3 1 0.47 0 0
157 INT170114 ITGAM Regulation of Positive_regulation of ITGAL 1 0.04 1.07 0
158 INT77596 Binding of ITGA1 and VCAM1 1 0.10 0 0
159 INT275972 Binding of Itga2 and Gp6 1 0.05 0 0
160 INT170115 PECAM1 Regulation of ITGAL 1 0.00 1.07 0
161 INT331090 Binding of Ctsl and Itga2 1 0.10 0.2 0
162 INT77595 ITGA1 Positive_regulation of Binding of VCAM1 1 0.14 0 0
163 INT210416 ITGA4 Negative_regulation of CYP2D6 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for integrin complex. They are ordered first by their pain relevance and then by number of times they were reported in integrin complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78
2 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26
3 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34
4 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3
5 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16
6 INT64792 Positive_regulation of Gene_expression of ITGAM 39 0.69 23.21 6.71
7 INT10917 Positive_regulation of ITGAM 31 0.67 16.39 6.69
8 INT60700 Gene_expression of Itgax 93 0.71 51.89 6.57
9 INT61417 Gene_expression of ITGAL 36 0.75 29.62 6.15
10 INT53684 Negative_regulation of Gene_expression of ITGAM 23 0.59 14.36 5.66
11 INT10919 Positive_regulation of ITGB2 25 0.67 13.75 5.45
12 INT15173 Positive_regulation of Gene_expression of Itgam 59 0.49 21.89 5.43
13 INT56364 Regulation of Gene_expression of ITGAM 19 0.61 9.82 5.09
14 INT61252 Negative_regulation of Gene_expression of Itgam 38 0.54 16.48 5.01
15 INT49405 Gene_expression of Itgal 40 0.75 27.3 4.8
16 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
17 INT87322 Binding of ITGAL 23 0.47 15.73 4.68
18 INT57338 Gene_expression of ITGAX 31 0.75 24.62 4.39
19 INT51831 Negative_regulation of ITGA2B 20 0.57 10.59 3.91
20 INT70326 Positive_regulation of Gene_expression of ITGB2 24 0.67 15.42 3.86
21 INT33739 Gene_expression of ITGA2B 25 0.75 8.19 3.6
22 INT61259 Negative_regulation of Itgam 16 0.47 11.11 3.27
23 INT53683 Negative_regulation of Gene_expression of ITGB2 10 0.57 9.11 3.2
24 INT67333 Negative_regulation of ITGB2 10 0.41 6.92 3.06
25 INT15178 Positive_regulation of Positive_regulation of ITGAM 7 0.56 2.51 2.86
26 INT171117 Binding of Itgam 35 0.36 14.87 2.76
27 INT48391 Negative_regulation of Positive_regulation of ITGAM 5 0.43 3.13 2.46
28 INT88586 Positive_regulation of Itga7 4 0.67 0.89 2.36
29 INT61418 Positive_regulation of ITGAL 24 0.14 12.86 2.3
30 INT20991 Regulation of ITGAM 9 0.45 5.46 2.27
31 INT87323 Binding of ITGB2 16 0.47 9.91 2.24
32 INT67332 Negative_regulation of ITGA4 8 0.51 7.95 2.14
33 INT50676 Regulation of ITGA4 2 0.07 0.6 2.13
34 INT61262 Negative_regulation of Positive_regulation of Itgam 5 0.57 4.25 1.95
35 INT94117 Regulation of Gene_expression of Itgam 13 0.36 5.9 1.87
36 INT83627 Localization of ITGAM 7 0.78 7.26 1.83
37 INT210709 Regulation of Itgam 8 0.28 9.21 1.76
38 INT20992 Regulation of ITGB2 11 0.37 9.04 1.73
39 INT168602 Negative_regulation of Itgb1 3 0.21 1.29 1.73
40 INT6598 Gene_expression of ITGA2 9 0.46 4.88 1.72
41 INT12942 Regulation of ITGAL 8 0.35 3.29 1.57
42 INT99298 Positive_regulation of ITGA3 6 0.06 2.94 1.54
43 INT49404 Binding of Itgal 11 0.36 9.16 1.53
44 INT33133 Positive_regulation of ITGA2B 13 0.67 4.09 1.44
45 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
46 INT152885 Localization of Itgam 16 0.73 7.62 1.43
47 INT168683 Localization of ITGA4 2 0.12 0.61 1.4
48 INT168685 Regulation of Localization of ITGA4 1 0.07 0.61 1.4
49 INT56365 Regulation of Gene_expression of ITGB2 5 0.60 3.87 1.36
50 INT55476 Negative_regulation of ITGA2 8 0.55 3.55 1.33
51 INT114010 Gene_expression of Itga7 3 0.75 1.69 1.32
52 INT247903 Localization of ITGA1 1 0.06 5.69 1.32
53 INT79840 Binding of Itga2b 4 0.16 2.51 1.28
54 INT20397 Positive_regulation of Itgax 12 0.46 6.48 1.19
55 INT182168 Localization of ITGAX 3 0.73 2.71 1.17
56 INT6599 Binding of ITGA2 4 0.35 3.6 1.16
57 INT72599 Negative_regulation of Gene_expression of ITGA2 2 0.09 1.3 1.15
58 INT56492 Positive_regulation of ITGAX 2 0.49 2.95 1.14
59 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12
60 INT70329 Positive_regulation of Positive_regulation of ITGB2 3 0.67 0 1.06
61 INT60699 Negative_regulation of Gene_expression of Itgax 5 0.39 1.94 1.05
62 INT67156 Binding of ITGA4 6 0.14 2.63 1.03
63 INT71732 Negative_regulation of ITGAM 3 0.41 2 1
64 INT78014 Negative_regulation of ITGA5 1 0.01 1.71 0.98
65 INT126416 Gene_expression of Itga1 1 0.02 0.89 0.98
66 INT49406 Positive_regulation of Itgal 7 0.43 8.58 0.95
67 INT87329 Positive_regulation of Gene_expression of Itgax 15 0.64 10.85 0.93
68 INT81723 Regulation of Gene_expression of ITGAL 2 0.32 0.2 0.92
69 INT178803 Gene_expression of Itgb2 10 0.44 5.13 0.87
70 INT115964 Negative_regulation of ITGAL 7 0.34 3.76 0.86
71 INT113672 Positive_regulation of Gene_expression of ITGB1 3 0.49 1.4 0.86
72 INT58186 Gene_expression of ITGA1 10 0.25 3 0.84
73 INT58184 Gene_expression of Itga3 9 0.38 6.58 0.81
74 INT82803 Positive_regulation of Gene_expression of ITGA4 4 0.57 1.57 0.81
75 INT87321 Binding of ITGAX 4 0.47 3.72 0.8
76 INT115613 Regulation of Gene_expression of ITGA2B 3 0.44 1.43 0.8
77 INT117043 Gene_expression of Itga1 4 0.37 3.3 0.77
78 INT186135 Negative_regulation of Binding of ITGAL 5 0.34 3.27 0.74
79 INT33733 Binding of ITGA2B 12 0.36 3.86 0.71
80 INT82808 Positive_regulation of ITGA4 7 0.44 5.19 0.71
81 INT137204 Localization of Itgax 6 0.70 3.86 0.67
82 INT15171 Positive_regulation of Positive_regulation of Itgam 4 0.49 1.13 0.64
83 INT77147 Positive_regulation of Itgb5 1 0.39 0.17 0.62
84 INT102695 Localization of ITGAL 2 0.73 1.26 0.61
85 INT99000 Binding of Itga1 3 0.06 2.26 0.59
86 INT341563 Positive_regulation of ITGB4 1 0.38 2.58 0.59
87 INT20396 Negative_regulation of Positive_regulation of Itgax 4 0.22 1.01 0.57
88 INT72598 Positive_regulation of ITGA2 4 0.47 1.16 0.56
89 INT63357 Negative_regulation of Gene_expression of ITGAL 3 0.33 1.88 0.56
90 INT61945 Negative_regulation of Positive_regulation of ITGB2 3 0.41 1.35 0.56
91 INT154123 Regulation of Itga7 1 0.44 0.17 0.56
92 INT154125 Regulation of Gene_expression of Itga7 1 0.44 0.17 0.56
93 INT253299 Positive_regulation of Localization of Itgam 4 0.29 3.04 0.55
94 INT118891 Transcription of Itga2 1 0.03 0 0.54
95 INT98997 Negative_regulation of Itga1 2 0.07 2.05 0.53
96 INT145225 Transcription of ITGB1 1 0.10 0.1 0.52
97 INT133729 Positive_regulation of Gene_expression of ITGAL 8 0.49 2.96 0.48
98 INT79841 Binding of ITGAM 6 0.47 1.37 0.47
99 INT6603 Gene_expression of ITGA3 10 0.29 7.88 0.46
100 INT83273 Gene_expression of Itga2b 4 0.34 6.95 0.46
101 INT96152 Regulation of Gene_expression of Itgax 2 0.41 1.15 0.46
102 INT264200 Positive_regulation of Gene_expression of ITGAX 4 0.19 1.55 0.44
103 INT33737 Negative_regulation of Binding of ITGA2B 3 0.41 0.29 0.44
104 INT63424 Negative_regulation of Gene_expression of ITGA2B 2 0.57 0.9 0.42
105 INT100768 Binding of Itga1 1 0.13 1.37 0.4
106 INT277788 Negative_regulation of Gene_expression of Itgal 4 0.29 2.05 0.39
107 INT63422 Positive_regulation of Gene_expression of ITGA2B 4 0.67 1.11 0.39
108 INT192858 Phosphorylation of Itgam 4 0.47 1.71 0.38
109 INT126827 Negative_regulation of Itgax 4 0.57 2.06 0.36
110 INT79260 Negative_regulation of Itgal 2 0.37 2.11 0.33
111 INT119073 Negative_regulation of ITGB1 1 0.01 0.1 0.33
112 INT239861 Gene_expression of Itga2 5 0.65 1.32 0.32
113 INT91820 Regulation of ITGA2B 3 0.44 2.03 0.32
114 INT98999 Regulation of Itga1 2 0.21 1.9 0.32
115 INT219181 Negative_regulation of ITGA1 1 0.05 1.34 0.32
116 INT206605 Binding of Itgb5 1 0.11 0.41 0.32
117 INT316852 Positive_regulation of ITGA1 1 0.01 0.44 0.31
118 INT140187 Positive_regulation of Itga2 1 0.18 0.34 0.3
119 INT58185 Binding of Itga3 1 0.12 2.79 0.3
120 INT236352 Positive_regulation of Binding of Itgam 4 0.36 2.92 0.29
121 INT114900 Negative_regulation of Positive_regulation of ITGAL 1 0.01 1.32 0.29
122 INT239863 Negative_regulation of Gene_expression of Itga2 1 0.03 0.8 0.29
123 INT171788 Positive_regulation of Binding of Itga2 1 0.02 0.94 0.28
124 INT171790 Regulation of Binding of Itga2 1 0.01 0.93 0.28
125 INT99005 Positive_regulation of Itgb2 8 0.39 6.36 0.27
126 INT98996 Regulation of Itgb2 2 0.25 2.09 0.27
127 INT171789 Binding of Itga2 1 0.02 0.92 0.27
128 INT91496 Binding of Itgax 4 0.34 2.14 0.26
129 INT119451 Negative_regulation of Itga2b 1 0.04 0.35 0.26
130 INT12940 Positive_regulation of Transcription of ITGAL 1 0.02 0.09 0.26
131 INT12941 Transcription of ITGAL 1 0.03 0.09 0.26
132 INT152888 Transcription of Itgam 4 0.44 1.29 0.25
133 INT125780 Negative_regulation of Itgb3 2 0.39 0.66 0.25
134 INT264201 Negative_regulation of Gene_expression of ITGAX 1 0.16 1.29 0.25
135 INT317818 Regulation of ITGA2 4 0.23 1.18 0.24
136 INT185234 Transcription of Itgax 1 0.66 4.83 0.24
137 INT61416 Positive_regulation of Positive_regulation of ITGAL 4 0.11 0.85 0.23
138 INT79259 Regulation of Itgal 4 0.40 2.94 0.23
139 INT117808 Positive_regulation of Gene_expression of Itgal 3 0.10 2.12 0.23
140 INT6604 Binding of ITGA3 3 0.14 3.37 0.22
141 INT100770 Negative_regulation of Itga1 1 0.11 0.71 0.22
142 INT64369 Negative_regulation of Binding of ITGA2 1 0.06 0.07 0.21
143 INT225973 Binding of Itgb1 2 0.08 1.1 0.2
144 INT245860 Gene_expression of Itgb1 8 0.42 5.37 0.19
145 INT91278 Positive_regulation of Itgb3 4 0.31 1.73 0.19
146 INT114943 Gene_expression of Itgb5 2 0.04 0.09 0.19
147 INT114944 Regulation of Gene_expression of Itgb5 1 0.02 0 0.19
148 INT355260 Positive_regulation of Phosphorylation of Itgam 1 0.09 1.03 0.18
149 INT233246 Localization of Itgb3 3 0.54 0.25 0.17
150 INT239859 Protein_catabolism of Itgb3 1 0.64 0.25 0.17
151 INT131467 Binding of Itga7 1 0.35 0.09 0.17
152 INT83274 Negative_regulation of Gene_expression of Itga2b 2 0.11 1.71 0.16
153 INT189311 Gene_expression of ITGB4 2 0.41 0.53 0.16
154 INT80386 Positive_regulation of Negative_regulation of ITGA2B 1 0.49 0.2 0.16
155 INT99002 Positive_regulation of Itga1 1 0.08 1.4 0.16
156 INT235724 Localization of Itgal 2 0.07 0.94 0.15
157 INT344816 Regulation of Gene_expression of Itgb2 1 0.07 0.56 0.15
158 INT188592 Regulation of ITGAX 1 0.60 0 0.15
159 INT216725 Negative_regulation of Positive_regulation of ITGA2B 1 0.41 0 0.15
160 INT288159 Regulation of Gene_expression of Itgal 1 0.15 1.16 0.14
161 INT279236 Localization of ITGB2 1 0.17 0.43 0.14
162 INT117042 Localization of Itga1 1 0.15 0.54 0.14
163 INT6600 Negative_regulation of Gene_expression of ITGA3 1 0.22 2.96 0.13
164 INT58183 Negative_regulation of Itga3 1 0.18 1.2 0.13
165 INT91498 Positive_regulation of Itga2b 1 0.22 0.49 0.13
166 INT222042 Localization of ITGB1 3 0.29 0.72 0.12
167 INT267140 Positive_regulation of Localization of ITGAM 2 0.25 2.06 0.12
168 INT32309 Regulation of Itga7 1 0.12 0.37 0.12
169 INT54841 Regulation of Positive_regulation of ITGB2 1 0.26 0.34 0.12
170 INT264193 Regulation of Gene_expression of ITGAX 1 0.17 0.41 0.12
171 INT115521 Gene_expression of Itga2 1 0.04 0.62 0.12
172 INT233217 Gene_expression of Itgb3 16 0.75 0.98 0.11
173 INT273704 Binding of Itgb2 3 0.20 2.59 0.1
174 INT115520 Regulation of Itga2 2 0.01 0.46 0.1
175 INT189315 Protein_catabolism of ITGA1 1 0.33 0 0.1
176 INT32194 Positive_regulation of Itga7 1 0.05 0.38 0.1
177 INT286266 Positive_regulation of Regulation of ITGB2 1 0.07 1.33 0.1
178 INT189317 Protein_catabolism of ITGA4 1 0.28 0 0.1
179 INT117809 Positive_regulation of Positive_regulation of Itgal 1 0.04 0.84 0.09
180 INT233253 Regulation of Gene_expression of Itgb3 1 0.41 0.34 0.09
181 INT181461 Regulation of Transcription of ITGAM 1 0.09 1.49 0.08
182 INT334511 Positive_regulation of Transcription of ITGB2 1 0.02 1.48 0.08
183 INT273698 Positive_regulation of Positive_regulation of Itgb2 1 0.39 0.22 0.08
184 INT334515 Transcription of ITGB2 1 0.02 1.47 0.08
185 INT181460 Transcription of ITGAM 1 0.17 1.4 0.08
186 INT67155 Negative_regulation of Binding of ITGA4 1 0.01 0.1 0.08
187 INT33742 Protein_catabolism of ITGA2B 1 0.51 0 0.07
188 INT185230 Regulation of Itgax 1 0.56 3.32 0.07
189 INT171141 Positive_regulation of Itga1 1 0.02 0.41 0.07
190 INT200602 Positive_regulation of Gene_expression of Itga2b 1 0.04 1.21 0.07
191 INT277786 Negative_regulation of Binding of Itgal 1 0.29 0.22 0.07
192 INT72601 Gene_expression of ITGA5 3 0.32 0.51 0.06
193 INT200608 Regulation of Gene_expression of Itga2b 1 0.04 1.03 0.05
194 INT83483 Regulation of Regulation of ITGAL 2 0.01 0.3 0.04
195 INT341556 Binding of ITGB4 1 0.18 0 0.04
196 INT219663 Binding of Itgb3 1 0.08 1.18 0.03
197 INT264551 Positive_regulation of Binding of ITGA1 1 0.03 0.05 0.03
198 INT264546 Binding of ITGA1 1 0.02 0.05 0.03
199 INT233234 Negative_regulation of Gene_expression of Itgb3 3 0.29 0.65 0
200 INT33132 Positive_regulation of Positive_regulation of ITGA2B 2 0.49 0.3 0
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