GO:0008327

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Name methyl-CpG binding
Categary Function
Go Slim No
Go Link GO:0008327
Unique Molecular Interactions 38
Total Molecular Interactions 42
Total Single Events 526
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for methyl-CpG binding. They are ordered first by their pain relevance and then by number of times they were reported for methyl-CpG binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
2 INT135361 Prr14 Positive_regulation of Mecp2 1 0.24 0.15 0.64
3 INT135363 Mecp2 Positive_regulation of Mbd1 1 0.50 0.15 0.64
4 INT804 Aap Negative_regulation of MBD2 1 0.01 0 0.57
5 INT247265 Mecp2 Regulation of Fos 1 0.25 0.38 0.52
6 INT135360 Binding of Mecp2 and Aadac 1 0.03 0.19 0.51
7 INT1066 Gm5720 Positive_regulation of MBD2 1 0.00 0.73 0.42
8 INT280479 Binding of Mecp2 and Sin3a 1 0.00 1.54 0.35
9 INT47600 Ccno Regulation of MBD2 1 0.00 0.22 0.24
10 INT280475 Binding of Bdnf and Mecp2 1 0.11 0.92 0.22
11 INT280478 Mecp2 Negative_regulation of Gene_expression of Bdnf 1 0.13 0.94 0.22
12 INT280487 Negative_regulation of Binding of Mecp2 and Sin3a 1 0.00 0.77 0.18
13 INT318969 Mecp2 Regulation of Gene_expression of Bdnf 1 0.17 0.28 0.17
14 INT87092 Binding of PPP4C and MBD2 1 0.05 0 0.16
15 INT247266 Binding of Mecp2 and Fos 1 0.30 0.18 0.13
16 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13
17 INT286683 Gopc Positive_regulation of MBD2 1 0.01 1.07 0.11
18 INT247264 Mecp2 Positive_regulation of Gtf2i 1 0.02 0 0.08
19 INT248209 Camk2a Positive_regulation of Phosphorylation of Mecp2 1 0.52 0 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for methyl-CpG binding. They are ordered first by their pain relevance and then by number of times they were reported in methyl-CpG binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT152 Negative_regulation of MBD2 31 0.38 3.95 11.31
2 INT29988 Gene_expression of Mecp2 27 0.78 5.45 9.47
3 INT113 Positive_regulation of MBD2 33 0.49 6.76 7.49
4 INT144539 Phosphorylation of Mecp2 3 0.82 6.18 6.2
5 INT135359 Positive_regulation of Mecp2 4 0.70 4.35 6.05
6 INT318967 Gene_expression of Mecp2 9 0.77 11.52 3.55
7 INT38374 Regulation of MBD2 8 0.10 0.72 2.09
8 INT144541 Negative_regulation of Gene_expression of Mecp2 3 0.42 1.43 1.9
9 INT247261 Negative_regulation of Mecp2 1 0.42 1.71 1.78
10 INT144538 Regulation of Phosphorylation of Mecp2 2 0.45 1.87 1.77
11 INT135355 Binding of Mecp2 4 0.37 0.83 1.72
12 INT144542 Positive_regulation of Phosphorylation of Mecp2 2 0.68 1.43 1.5
13 INT318963 Positive_regulation of Mecp2 5 0.50 1.78 1.49
14 INT247263 Regulation of Mecp2 4 0.60 1.31 1.32
15 INT280467 Negative_regulation of Mecp2 5 0.59 3.33 1.21
16 INT22946 Gene_expression of MBD2 4 0.25 0.26 0.98
17 INT247262 Negative_regulation of Positive_regulation of Mecp2 1 0.42 0.85 0.8
18 INT318962 Negative_regulation of Gene_expression of Mecp2 2 0.43 0.5 0.7
19 INT183395 Localization of Mecp2 4 0.75 1.76 0.69
20 INT280463 Binding of Mecp2 3 0.37 4 0.63
21 INT247256 Negative_regulation of Phosphorylation of Mecp2 1 0.57 0.63 0.52
22 INT8053 Regulation of Negative_regulation of MBD2 1 0.16 0 0.5
23 INT247259 Positive_regulation of Gene_expression of Mecp2 1 0.68 0.13 0.46
24 INT280468 Positive_regulation of Localization of Mecp2 3 0.50 1.76 0.45
25 INT318964 Negative_regulation of Localization of Mecp2 1 0.43 0.53 0.43
26 INT280462 Positive_regulation of Phosphorylation of Mecp2 1 0.12 1.69 0.37
27 INT135356 Positive_regulation of Binding of Mecp2 1 0.50 0.1 0.36
28 INT338882 Regulation of Regulation of Mecp2 1 0.24 0.56 0.29
29 INT248208 Phosphorylation of Mecp2 3 0.82 1.17 0.26
30 INT247260 Regulation of Gene_expression of Mecp2 1 0.60 0.06 0.21
31 INT41148 Binding of MBD2 1 0.18 0 0.17
32 INT46899 Negative_regulation of Positive_regulation of MBD2 1 0.00 0 0.1
33 INT27567 Positive_regulation of Gene_expression of MBD2 1 0.01 0 0.09
34 INT47659 Localization of MBD2 2 0.70 0.72 0.08
35 INT120535 Positive_regulation of Negative_regulation of MBD2 1 0.01 0.22 0.07
36 INT320943 Negative_regulation of Phosphorylation of Mecp2 1 0.43 0.33 0
37 INT320939 Transcription of Mecp2 1 0.69 0.2 0
38 INT328132 Regulation of Mecp2 1 0.40 1 0
39 INT320952 Regulation of Gene_expression of Mecp2 1 0.45 0.87 0
40 INT320949 Negative_regulation of Binding of Mecp2 1 0.43 0.21 0
41 INT320950 Positive_regulation of Gene_expression of Mecp2 1 0.50 1.24 0
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