GO:0008366

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Name axon ensheathment
Categary Process
Go Slim No
Go Link GO:0008366
Unique Molecular Interactions 33
Total Molecular Interactions 44
Total Single Events 420
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for axon ensheathment. They are ordered first by their pain relevance and then by number of times they were reported for axon ensheathment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
2 INT154778 Cldn11 Positive_regulation of Eae1 4 0.12 3.24 1.03
3 INT49085 Negative_regulation of MBP Positive_regulation of Eae1 1 0.00 1.51 0.87
4 INT49084 MBP Positive_regulation of Eae1 1 0.00 1.49 0.86
5 INT128945 Binding of MBP and Mog 1 0.01 1.59 0.86
6 INT48304 Positive_regulation of MBP Positive_regulation of PLP1 1 0.10 0.97 0.64
7 INT48303 MBP Positive_regulation of PLP1 1 0.10 0.97 0.64
8 INT153797 NUBPL Negative_regulation of PPARD 1 0.02 0.69 0.64
9 INT139429 LPA Positive_regulation of Negative_regulation of MBP 1 0.00 0.78 0.56
10 INT72345 MBP Positive_regulation of Localization of PRSS1 1 0.00 0.22 0.41
11 INT139683 Binding of Cldn11 and 2410016O06Rik 1 0.02 1.06 0.4
12 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
13 INT159201 Binding of Ppard and Ppara 1 0.01 0.68 0.28
14 INT180245 Binding of Plp1 and Uchl1 1 0.03 0.47 0.27
15 INT180248 Binding of Gad1 and Plp1 1 0.08 0.22 0.21
16 INT254492 Dtx1 Regulation of Cldn11 1 0.03 0 0.09
17 INT312841 Pou3f1 Regulation of Gene_expression of Plp1 1 0.24 0.16 0.09
18 INT312843 Egr2 Regulation of Gene_expression of Plp1 1 0.31 0.16 0.09
19 INT334686 Olig1 Regulation of Plp1 1 0.17 0.55 0.06
20 INT334684 Eae1 Regulation of Plp1 1 0.05 0.5 0.06
21 INT334685 Olig1 Regulation of Gene_expression of Plp1 1 0.17 0.55 0.06
22 INT334688 Eae1 Regulation of Gene_expression of Plp1 1 0.05 0.5 0.06
23 INT302984 MBP Positive_regulation of AHR 1 0.31 0.3 0.06
24 INT106823 Binding of MBP and PAPPA 2 0.17 3.89 0.05
25 INT206846 ESR1 Regulation of Gene_expression of PLP1 1 0.06 1.02 0.05
26 INT206848 PLP1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
27 INT290033 Binding of PPARD and NR1H4 1 0.01 0.39 0
28 INT345168 Binding of Lpar1 and Ppard 1 0.03 0.21 0
29 INT290025 Binding of INS and PPARD 1 0.03 0.47 0
30 INT290030 Binding of PPARD and PPARG 1 0.09 0.38 0
31 INT290023 Binding of PPARD and RXRG 1 0.03 0.39 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for axon ensheathment. They are ordered first by their pain relevance and then by number of times they were reported in axon ensheathment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT541 Positive_regulation of MBP 31 0.67 28.56 12.24
2 INT17741 Gene_expression of MBP 67 0.78 23.67 9.65
3 INT14637 Negative_regulation of MBP 19 0.43 7.06 7.18
4 INT61114 Gene_expression of Ppard 23 0.75 14.98 6.62
5 INT48308 Binding of PLP1 7 0.48 9.59 6.09
6 INT48307 Positive_regulation of PLP1 5 0.66 8.42 5.09
7 INT48246 Gene_expression of PLP1 18 0.64 10.33 4.73
8 INT84891 Gene_expression of PPARD 10 0.78 6.8 3.64
9 INT536 Binding of MBP 17 0.48 6.52 3.56
10 INT102034 Positive_regulation of Ppard 10 0.69 3.97 3.17
11 INT84890 Negative_regulation of PPARD 7 0.59 3.27 3.1
12 INT112758 Binding of Ppard 7 0.37 3.6 2.87
13 INT15555 Localization of PLP1 6 0.60 3.35 2.75
14 INT102033 Negative_regulation of Ppard 5 0.37 4.14 2.48
15 INT8466 Binding of Plp1 5 0.48 5.07 2.29
16 INT3151 Localization of MBP 27 0.80 7.58 2.28
17 INT14488 Regulation of MBP 5 0.25 5.17 2.25
18 INT101516 Positive_regulation of PPARD 8 0.49 4.75 2.19
19 INT44320 Positive_regulation of Cldn11 5 0.39 2.95 1.81
20 INT194242 Positive_regulation of Gene_expression of MBP 9 0.45 4.1 1.71
21 INT95056 Positive_regulation of Gene_expression of Ppard 5 0.52 3.84 1.6
22 INT84889 Positive_regulation of Gene_expression of PPARD 4 0.70 2.94 1.49
23 INT84888 Binding of PPARD 5 0.48 2.82 1.45
24 INT302990 Protein_catabolism of MBP 5 0.88 3.75 1.42
25 INT132495 Negative_regulation of Gene_expression of Ppard 4 0.44 2.64 1.28
26 INT48687 Gene_expression of Plp1 7 0.54 3.51 1.03
27 INT112759 Negative_regulation of Binding of Ppard 2 0.39 2.08 0.99
28 INT254471 Gene_expression of Cldn11 1 0.49 0.8 0.96
29 INT120485 Positive_regulation of Plp1 1 0.33 2.2 0.9
30 INT204825 Negative_regulation of Plp1 3 0.33 2.96 0.87
31 INT84892 Negative_regulation of Gene_expression of PPARD 2 0.43 1.85 0.83
32 INT194239 Regulation of Gene_expression of MBP 4 0.40 0.48 0.78
33 INT48305 Positive_regulation of Positive_regulation of MBP 1 0.10 0.98 0.73
34 INT48306 Positive_regulation of Positive_regulation of PLP1 1 0.42 0.97 0.64
35 INT139677 Localization of Cldn11 3 0.59 1.42 0.58
36 INT139431 Positive_regulation of Negative_regulation of MBP 1 0.01 0.77 0.55
37 INT154775 Binding of Cldn11 1 0.36 1.92 0.51
38 INT101515 Negative_regulation of Positive_regulation of PPARD 2 0.35 0.68 0.47
39 INT84893 Negative_regulation of Binding of PPARD 1 0.43 0.5 0.46
40 INT44319 Positive_regulation of Positive_regulation of Cldn11 1 0.39 0.12 0.46
41 INT132946 Negative_regulation of Positive_regulation of Ppard 1 0.42 0.09 0.44
42 INT204851 Transcription of Plp1 1 0.40 1.38 0.42
43 INT180234 Negative_regulation of Gene_expression of Plp1 1 0.08 1.54 0.42
44 INT135835 Positive_regulation of Gene_expression of PLP1 1 0.21 2.44 0.41
45 INT245361 Regulation of Plp1 1 0.35 1.15 0.38
46 INT94304 Negative_regulation of Gene_expression of PLP1 2 0.20 1.02 0.36
47 INT94305 Negative_regulation of PLP1 1 0.03 4.28 0.35
48 INT144419 Regulation of Ppard 1 0.24 0.91 0.3
49 INT61115 Localization of Ppard 2 0.66 1.99 0.28
50 INT254476 Negative_regulation of Cldn11 1 0.43 0.59 0.28
51 INT254487 Regulation of Negative_regulation of Cldn11 1 0.33 0.6 0.28
52 INT159198 Positive_regulation of Binding of Ppard 1 0.34 0.68 0.28
53 INT349070 Positive_regulation of Binding of MBP 1 0.25 0.91 0.26
54 INT14636 Transcription of MBP 2 0.54 0.47 0.23
55 INT14635 Negative_regulation of Transcription of MBP 1 0.02 0.47 0.23
56 INT154776 Regulation of Cldn11 2 0.33 0.4 0.22
57 INT216361 Negative_regulation of Gene_expression of MBP 3 0.43 0.9 0.19
58 INT254477 Negative_regulation of Gene_expression of Cldn11 1 0.31 0.46 0.15
59 INT186516 Regulation of PPARD 1 0.15 1.12 0.11
60 INT48686 Localization of Plp1 7 0.07 0.71 0.09
61 INT254483 Regulation of Gene_expression of Cldn11 1 0.33 0 0.09
62 INT223571 Localization of PPARD 1 0.73 0.39 0.06
63 INT206882 Regulation of PLP1 1 0.13 0.84 0.04
64 INT252396 Transcription of PLP1 1 0.03 0.05 0
65 INT302993 Negative_regulation of Localization of MBP 1 0.37 0.08 0
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