GO:0008484

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Name sulfuric ester hydrolase activity
Categary Function
Go Slim No
Go Link GO:0008484
Unique Molecular Interactions 43
Total Molecular Interactions 47
Total Single Events 417
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sulfuric ester hydrolase activity. They are ordered first by their pain relevance and then by number of times they were reported for sulfuric ester hydrolase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
2 INT124742 ARSA Positive_regulation of Localization of CSF2 1 0.10 0.15 0.91
3 INT124743 ARSA Negative_regulation of PTGER2 1 0.03 0.15 0.85
4 INT124744 ARSA Negative_regulation of Gene_expression of PTGER2 1 0.03 0.15 0.85
5 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
6 INT125543 Arsa Negative_regulation of Phosphorylation of Nfkbia 1 0.00 0.52 0.68
7 INT94075 ARSA Negative_regulation of Gene_expression of IL4 1 0.28 0.26 0.62
8 INT125546 Arsa Negative_regulation of Gene_expression of PTGS2 1 0.00 0.53 0.58
9 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
10 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
11 INT248135 Binding of IDS and ACCS 1 0.09 1.12 0.51
12 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
13 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
14 INT273893 ARSA Positive_regulation of HSD11B1 1 0.00 0.61 0.4
15 INT94073 ARSA Negative_regulation of Transcription of IL4 1 0.20 0.16 0.31
16 INT94076 ARSA Negative_regulation of Gene_expression of IL2 1 0.13 0.09 0.3
17 INT94072 ARSA Regulation of Gene_expression of IL2 1 0.07 0.09 0.29
18 INT94074 ARSA Regulation of Gene_expression of IK 1 0.01 0.06 0.27
19 INT264569 Binding of STS and ATF7IP 1 0.03 0.15 0.25
20 INT257844 STS Positive_regulation of Negative_regulation of CST7 1 0.01 0.24 0.19
21 INT208459 Galns Negative_regulation of Negative_regulation of BCAN 1 0.01 0.44 0.13
22 INT277890 Binding of Ids and Tas2r111-ps2 1 0.08 0.5 0.09
23 INT277889 Regulation of Binding of Ids and Tas2r111-ps2 1 0.09 0.5 0.09
24 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09
25 INT264568 Binding of STS and CYP1A2 1 0.20 0.18 0.06
26 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05
27 INT248134 IDS Positive_regulation of CHDH 1 0.08 1.52 0.05
28 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05
29 INT191590 Binding of AMBP and Arsb 1 0.00 1.82 0.04
30 INT290727 Binding of Prdm6 and Arsi 1 0.01 0.17 0.04
31 INT220909 GNS Negative_regulation of Gene_expression of MMP13 1 0.00 0 0.03
32 INT220910 GNS Negative_regulation of MMP1 1 0.01 0 0.03
33 INT220914 GNS Negative_regulation of Phosphorylation of MAPK8 1 0.00 0.05 0.03
34 INT220915 GNS Negative_regulation of MMP13 1 0.00 0 0.03
35 INT220912 GNS Negative_regulation of Phosphorylation of JUN 1 0.00 0 0
36 INT277892 IDS Regulation of Ids 1 0.18 0.41 0
37 INT106380 ARSA Regulation of Gene_expression of BAX 1 0.06 0.12 0
38 INT190902 Binding of HBN1 and Arsb 1 0.00 1.88 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for sulfuric ester hydrolase activity. They are ordered first by their pain relevance and then by number of times they were reported in sulfuric ester hydrolase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT105993 Gene_expression of IDS 26 0.78 10.83 2.41
2 INT3798 Negative_regulation of GNS 5 0.26 3.18 2.21
3 INT59194 Gene_expression of STS 18 0.59 6.74 1.89
4 INT227663 Localization of IDS 14 0.63 7.64 1.85
5 INT227660 Negative_regulation of Localization of IDS 2 0.23 3.81 1.57
6 INT302658 Binding of ARSA 1 0.07 0.92 1.53
7 INT113423 Binding of GNS 3 0.18 1.66 1.16
8 INT43295 Regulation of Arsa 1 0.43 0 1.15
9 INT105991 Negative_regulation of IDS 12 0.38 6.31 1.04
10 INT200462 Binding of IDS 13 0.31 4.95 1
11 INT217744 Positive_regulation of GNS 4 0.24 1.39 1
12 INT82687 Gene_expression of Arsi 4 0.57 2.6 0.97
13 INT99289 Localization of STS 8 0.79 6.5 0.92
14 INT35367 Gene_expression of Galns 4 0.61 0.45 0.89
15 INT104298 Negative_regulation of ARSA 2 0.28 0.56 0.89
16 INT71614 Localization of GNS 3 0.78 1.49 0.84
17 INT176467 Gene_expression of Arsa 1 0.58 2.62 0.83
18 INT96649 Gene_expression of ARSA 5 0.65 2.82 0.8
19 INT302660 Positive_regulation of Gene_expression of ARSA 1 0.10 0.88 0.77
20 INT99290 Positive_regulation of STS 16 0.43 6.96 0.75
21 INT38828 Negative_regulation of STS 14 0.44 7.27 0.68
22 INT125542 Phosphorylation of Arsa 1 0.02 0.52 0.67
23 INT217743 Gene_expression of GNS 3 0.32 1.37 0.65
24 INT217719 Positive_regulation of IDS 19 0.40 3.93 0.63
25 INT170284 Gene_expression of Arsb 9 0.65 9.12 0.63
26 INT182792 Regulation of STS 4 0.47 2.91 0.61
27 INT203748 Binding of STS 8 0.41 0.83 0.53
28 INT217723 Regulation of IDS 15 0.25 2.12 0.49
29 INT104297 Regulation of ARSA 1 0.18 1.05 0.49
30 INT277886 Localization of Ids 3 0.73 1.09 0.48
31 INT302661 Negative_regulation of Negative_regulation of ARSA 1 0.08 0.13 0.44
32 INT340829 Positive_regulation of Arsi 1 0.02 1.76 0.39
33 INT302663 Positive_regulation of ARSA 1 0.10 0.36 0.38
34 INT67899 Localization of Arsi 1 0.60 0.28 0.38
35 INT340830 Binding of Arsi 1 0.01 1.66 0.37
36 INT190900 Binding of Arsb 5 0.35 17.18 0.35
37 INT105992 Positive_regulation of Gene_expression of IDS 4 0.69 0.84 0.35
38 INT217745 Positive_regulation of Protein_catabolism of GNS 1 0.01 0.34 0.33
39 INT217741 Positive_regulation of Localization of GNS 1 0.01 0.34 0.33
40 INT217740 Protein_catabolism of GNS 1 0.01 0.34 0.32
41 INT75172 Protein_catabolism of Galns 3 0.45 0.66 0.3
42 INT42095 Positive_regulation of Galns 2 0.04 0.57 0.29
43 INT310681 Negative_regulation of ARSB 1 0.56 6.95 0.29
44 INT277882 Gene_expression of Ids 5 0.71 1.6 0.26
45 INT277878 Binding of Ids 4 0.34 0.8 0.24
46 INT345359 Positive_regulation of Ids 1 0.50 0.27 0.24
47 INT20296 Localization of Galns 1 0.02 0.3 0.23
48 INT170285 Positive_regulation of Gene_expression of Arsb 1 0.40 0.65 0.21
49 INT302669 Regulation of Positive_regulation of STS 1 0.34 0.99 0.2
50 INT182865 Localization of ARSA 1 0.24 1.27 0.15
51 INT310677 Localization of ARSB 1 0.71 5.72 0.14
52 INT153233 Negative_regulation of Ids 5 0.40 2.1 0.12
53 INT244122 Negative_regulation of Arsa 1 0.42 0 0.12
54 INT310680 Gene_expression of ARSB 1 0.64 6.28 0.12
55 INT277879 Positive_regulation of Gene_expression of Ids 3 0.44 0.14 0.11
56 INT3649 Positive_regulation of Arsa 1 0.50 0 0.1
57 INT345357 Protein_catabolism of Ids 1 0.57 0.2 0.09
58 INT28796 Binding of Galns 1 0.03 0.07 0.07
59 INT113424 Regulation of GNS 1 0.00 0.17 0.07
60 INT345361 Positive_regulation of Positive_regulation of Ids 1 0.44 0.41 0.06
61 INT223371 Protein_catabolism of IDS 2 0.48 0.23 0.04
62 INT318627 Regulation of Arsb 1 0.17 2.74 0.04
63 INT248136 Negative_regulation of Protein_catabolism of IDS 1 0.23 0.09 0.04
64 INT310683 Protein_catabolism of ARSB 1 0.73 1.85 0.04
65 INT310682 Regulation of ARSB 1 0.43 0.98 0.04
66 INT310679 Positive_regulation of ARSB 1 0.39 2.36 0.04
67 INT319126 Negative_regulation of Gene_expression of STS 7 0.07 0.83 0.03
68 INT348454 Transcription of STS 1 0.05 0.73 0.03
69 INT190901 Negative_regulation of Arsb 2 0.19 2.67 0
70 INT271151 Transcription of IDS 1 0.54 0.06 0
71 INT320099 Protein_catabolism of STS 1 0.68 1.84 0
72 INT210810 Positive_regulation of Positive_regulation of STS 1 0.19 0 0
73 INT345360 Regulation of Gene_expression of Ids 1 0.39 0 0
74 INT227666 Negative_regulation of Gene_expression of IDS 1 0.04 0.25 0
75 INT318626 Positive_regulation of Arsb 1 0.32 2.1 0
76 INT227662 Positive_regulation of Positive_regulation of IDS 1 0.04 0.2 0
77 INT246181 Regulation of Regulation of IDS 1 0.01 0.09 0
78 INT318625 Localization of Arsb 1 0.52 2.04 0
79 INT227669 Positive_regulation of Localization of IDS 1 0.04 0.15 0
80 INT348448 Positive_regulation of Gene_expression of STS 1 0.04 0.61 0
81 INT220940 Phosphorylation of GNS 1 0.01 0 0
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