GO:0008509

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Name anion transmembrane transporter activity
Categary Function
Go Slim No
Go Link GO:0008509
Unique Molecular Interactions 74
Total Molecular Interactions 89
Total Single Events 691
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for anion transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported for anion transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
2 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
3 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
4 INT69291 Cftr Positive_regulation of Localization of Slc4a8 1 0.04 0.38 0.51
5 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
6 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
7 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
8 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
9 INT80049 Adcyap1 Positive_regulation of Positive_regulation of Slc4a4 1 0.19 0 0.2
10 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
11 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
12 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
13 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
14 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
15 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
16 INT207350 TBXA2R Regulation of Gene_expression of ABCA1 1 0.10 0 0.17
17 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
18 INT298448 Binding of SLC4A1 and Slc4a3 1 0.39 1.89 0.15
19 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
20 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14
21 INT207360 PTGDS Negative_regulation of Negative_regulation of ABCA1 1 0.25 0 0.14
22 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
23 INT51367 Slc14a2 Positive_regulation of Localization of Slc4a4 1 0.03 0.1 0.14
24 INT207353 ZNF398 Regulation of ABCA1 1 0.00 0 0.14
25 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
26 INT212139 Slc4a3 Positive_regulation of Cl 1 0.07 0 0.12
27 INT72729 Adcyap1 Positive_regulation of Localization of Slc4a4 1 0.23 0 0.12
28 INT212138 Slc4a3 Positive_regulation of Gene_expression of Cl 1 0.07 0 0.12
29 INT293236 IDO1 Regulation of ABCA1 1 0.00 0 0.11
30 INT42224 ABCA1 Positive_regulation of CYBB 1 0.01 0 0.09
31 INT350106 Binding of SLC4A3 and SLC4A1 1 0.13 2.78 0.09
32 INT42225 Binding of ABCA1 and DECR1 1 0.02 0 0.08
33 INT137256 BCL2L11 Regulation of SLC4A1 1 0.24 0.99 0.08
34 INT289258 Binding of ABCA1 and Il6ra 1 0.00 0.33 0.07
35 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
36 INT257511 Regulation of Binding of Slc12a2 and Slc4a4 1 0.02 0.16 0.06
37 INT257510 Binding of Slc12a2 and Slc4a4 1 0.01 0.16 0.06
38 INT293233 IDO1 Positive_regulation of ABCA1 1 0.01 0 0.06
39 INT339583 Binding of ABCA1 and RPE 1 0.03 1.38 0.05
40 INT339587 Positive_regulation of Binding of ABCA1 and RPE 1 0.04 1.38 0.05
41 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05
42 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05
43 INT257513 Regulation of Binding of Slc4a4 and H47 1 0.00 0.08 0.03
44 INT257509 Binding of Slc12a4 and Slc4a4 1 0.00 0.08 0.03
45 INT257512 Binding of Slc4a4 and H47 1 0.00 0.08 0.03
46 INT230136 OSBPL8 Regulation of Binding of ABCA1 1 0.07 0.17 0.03
47 INT244656 Binding of S100B and SLC4A1 1 0.14 1.72 0.03
48 INT207343 Negative_regulation of CPOX Negative_regulation of Gene_expression of ABCA1 1 0.09 0 0.03
49 INT257508 Regulation of Binding of Slc12a4 and Slc4a4 1 0.00 0.08 0.03
50 INT284392 Binding of ABCA1 and Vegfa 1 0.00 0.71 0
51 INT229927 CD59 Negative_regulation of Binding of ABCA1 1 0.01 0 0
52 INT229923 Binding of ABCA1 and C9 1 0.00 0.74 0
53 INT296954 NRIP1 Negative_regulation of Gene_expression of UCP1 1 0.30 1.05 0
54 INT284372 Binding of ABCA1 and AMT 1 0.00 0 0
55 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0
56 INT297056 Binding of ABCA1 and Oas1b 1 0.00 0.13 0
57 INT117795 ABCA1 Regulation of GHRL 1 0.00 0 0
58 INT284393 Positive_regulation of Binding of ABCA1 and Vegfa 1 0.00 0.36 0
59 INT326085 Prkaca Regulation of Phosphorylation of ABCA1 1 0.02 0.44 0
60 INT181121 SLC4A1 Regulation of Cks1b 1 0.00 0.42 0
61 INT229981 Binding of ABCA1 and Cdca3 1 0.00 0.74 0
62 INT301178 UCP2 Negative_regulation of ROS1 1 0.29 1.41 0
63 INT144760 Binding of ABCA1 and Insr 1 0.00 0 0
64 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0
65 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
66 INT307283 Binding of ABCA1 and PMP2 1 0.00 0 0
67 INT326084 Prkaca Positive_regulation of Phosphorylation of ABCA1 1 0.06 0.44 0
68 INT217396 Binding of Abca1 and App 1 0.26 0.83 0
69 INT344712 Nr1h3 Regulation of Abca1 1 0.03 1.68 0
70 INT51366 Slc14a2 Regulation of Localization of Slc4a4 1 0.02 0 0
71 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0
72 INT301177 Gene_expression of UCP2 Positive_regulation of Gene_expression of ROS1 1 0.32 0.98 0
73 INT283461 Binding of IL2 and SLC4A2 1 0.01 0.98 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for anion transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported in anion transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11509 Localization of Slc4a4 66 0.67 2.34 19.05
2 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
3 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
4 INT17207 Positive_regulation of Localization of Slc4a4 18 0.58 0.09 6.02
5 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
6 INT48994 Localization of Slc4a8 17 0.46 3.29 4.69
7 INT9758 Positive_regulation of Slc4a4 13 0.40 0.26 4.37
8 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
9 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
10 INT48219 Gene_expression of SLC4A1 34 0.75 33.18 2.84
11 INT106286 Gene_expression of UCP2 15 0.77 7.24 2.78
12 INT30608 Regulation of Localization of Slc4a4 6 0.38 0.1 2.58
13 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
14 INT149125 Gene_expression of Slc4a3 25 0.78 3.45 2.41
15 INT30607 Negative_regulation of Localization of Slc4a4 9 0.37 1.48 1.88
16 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
17 INT283506 Gene_expression of SLC4A2 7 0.47 4 1.4
18 INT113858 Positive_regulation of SLC4A1 6 0.49 3.44 1.22
19 INT9757 Regulation of Slc4a4 3 0.23 0.31 1.17
20 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
21 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
22 INT190089 Binding of Abca1 5 0.36 2.21 0.83
23 INT283501 Positive_regulation of Gene_expression of SLC4A2 1 0.19 1.66 0.73
24 INT17206 Regulation of Positive_regulation of Slc4a4 1 0.23 0 0.7
25 INT283516 Localization of SLC4A2 1 0.21 0.8 0.69
26 INT164627 Positive_regulation of Gene_expression of ABCA1 9 0.61 3.95 0.67
27 INT277710 Regulation of Localization of ABCA1 1 0.04 1.73 0.56
28 INT38363 Negative_regulation of Slc4a4 4 0.36 0.09 0.5
29 INT283518 Negative_regulation of Gene_expression of SLC4A2 1 0.16 0.87 0.48
30 INT167468 Regulation of Gene_expression of ABCA1 5 0.52 0.08 0.43
31 INT209180 Transcription of ABCA1 4 0.47 1.09 0.39
32 INT345322 Regulation of Transcription of ABCA1 1 0.01 0 0.39
33 INT70449 Binding of SLC4A1 5 0.36 5.1 0.38
34 INT95693 Negative_regulation of SLC4A1 4 0.41 2.46 0.38
35 INT167122 Protein_catabolism of ABCA1 3 0.02 0.27 0.37
36 INT239295 Positive_regulation of Abca1 3 0.30 2.18 0.32
37 INT283504 Negative_regulation of Localization of SLC4A2 1 0.11 0.41 0.32
38 INT149126 Regulation of Gene_expression of Slc4a3 1 0.62 0.16 0.3
39 INT212132 Negative_regulation of Slc4a3 1 0.43 1.17 0.3
40 INT120711 Regulation of Localization of Slc4a8 1 0.16 0 0.29
41 INT120708 Positive_regulation of Localization of Slc4a8 1 0.40 0.27 0.29
42 INT239279 Regulation of Gene_expression of Abca1 2 0.44 2.42 0.26
43 INT344685 Positive_regulation of Binding of Abca1 1 0.12 0.76 0.26
44 INT284385 Positive_regulation of Localization of ABCA1 2 0.02 0.22 0.25
45 INT69288 Negative_regulation of Localization of Slc4a8 1 0.03 0.14 0.24
46 INT212127 Positive_regulation of Gene_expression of Slc4a3 1 0.50 0.93 0.23
47 INT239287 Transcription of Abca1 1 0.32 1.87 0.21
48 INT283503 Binding of SLC4A2 3 0.09 3.39 0.19
49 INT300227 Positive_regulation of Binding of ABCA1 1 0.41 1.85 0.19
50 INT277709 Regulation of Binding of ABCA1 1 0.04 0.52 0.19
51 INT216426 Regulation of UCP2 4 0.09 2.68 0.18
52 INT239308 Positive_regulation of Transcription of Abca1 1 0.28 0.67 0.18
53 INT212136 Positive_regulation of Slc4a3 1 0.70 0.54 0.17
54 INT217387 Regulation of Abca1 3 0.27 2.01 0.15
55 INT131227 Negative_regulation of Positive_regulation of Slc4a4 1 0.32 0 0.15
56 INT212135 Localization of Slc4a3 2 0.73 0.35 0.13
57 INT212129 Transcription of Slc4a3 1 0.69 0.07 0.13
58 INT125557 Regulation of SLC4A1 1 0.45 0.09 0.12
59 INT252846 Localization of SLC4A1 2 0.73 1.08 0.09
60 INT296984 Positive_regulation of UCP1 1 0.42 5.95 0.09
61 INT42227 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0 0.09
62 INT42226 Positive_regulation of Positive_regulation of ABCA1 1 0.02 0 0.09
63 INT19117 Gene_expression of Slc4a4 1 0.52 0.09 0.08
64 INT262061 Negative_regulation of Gene_expression of Abca1 1 0.19 0.68 0.08
65 INT188168 Binding of Slc4a3 4 0.47 1.06 0.07
66 INT212126 Gene_expression of Slc4a4 7 0.55 0.19 0.06
67 INT239296 Negative_regulation of Abca1 3 0.26 3.83 0.04
68 INT301189 Binding of UCP2 1 0.37 1.39 0.04
69 INT216428 Negative_regulation of UCP2 2 0.43 3.37 0.03
70 INT253595 Localization of Abca1 2 0.37 0.35 0.03
71 INT216430 Positive_regulation of UCP2 4 0.50 3.15 0
72 INT212137 Transcription of Slc4a4 1 0.55 0 0
73 INT326077 Positive_regulation of Transcription of ABCA1 1 0.41 0.22 0
74 INT326076 Phosphorylation of ABCA1 1 0.73 0.66 0
75 INT301185 Positive_regulation of Gene_expression of UCP2 1 0.69 2.73 0
76 INT301186 Regulation of Positive_regulation of UCP2 1 0.45 1.05 0
77 INT212133 Positive_regulation of Slc4a4 1 0.40 0 0
78 INT296964 Positive_regulation of Gene_expression of UCP1 1 0.31 2.01 0
79 INT301183 Regulation of Gene_expression of UCP2 1 0.61 0.59 0
80 INT216427 Negative_regulation of Positive_regulation of UCP2 1 0.06 1.07 0
81 INT301190 Positive_regulation of Binding of UCP2 1 0.50 0.89 0
82 INT296991 Positive_regulation of Binding of UCP1 1 0.31 1.13 0
83 INT296981 Gene_expression of UCP1 1 0.47 3.96 0
84 INT296975 Positive_regulation of Transcription of UCP1 1 0.28 1.77 0
85 INT212134 Regulation of Slc4a3 1 0.62 0.34 0
86 INT296965 Transcription of UCP1 1 0.33 1.75 0
87 INT293098 Transcription of Slc4a4 1 0.15 0.32 0
88 INT326083 Positive_regulation of Phosphorylation of ABCA1 1 0.61 0.66 0
89 INT296980 Positive_regulation of Positive_regulation of UCP1 1 0.28 0.61 0
90 INT257489 Positive_regulation of Gene_expression of Slc4a4 1 0.03 0 0
91 INT301182 Negative_regulation of Gene_expression of UCP2 1 0.58 0.88 0
92 INT296986 Binding of UCP1 1 0.23 1.13 0
93 INT283497 Negative_regulation of SLC4A2 1 0.14 0.95 0
94 INT301184 Localization of UCP2 1 0.74 0.12 0
95 INT216429 Positive_regulation of Positive_regulation of UCP2 1 0.10 1.06 0
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