GO:0008511

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Name sodium:potassium:chloride symporter activity
Categary Function
Go Slim No
Go Link GO:0008511
Unique Molecular Interactions 14
Total Molecular Interactions 19
Total Single Events 287
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sodium:potassium:chloride symporter activity. They are ordered first by their pain relevance and then by number of times they were reported for sodium:potassium:chloride symporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58
2 INT322812 Binding of SLC12A1 and MOCOS 1 0.00 1.69 1.49
3 INT247924 Slc12a5 Regulation of Gene_expression of Slc12a2 1 0.25 1.43 1.23
4 INT247925 Slc12a2 Regulation of Cl 1 0.01 1.44 1.23
5 INT244396 Binding of Cl and Slc12a2 1 0.03 0.88 0.76
6 INT157063 SLC12A1 Negative_regulation of CALCRL 1 0.00 0.34 0.73
7 INT322810 SLC12A1 Regulation of Binding of GRIA1 1 0.00 0.39 0.36
8 INT239790 SLC12A5 Regulation of SLC12A2 1 0.11 0.08 0.13
9 INT50079 Binding of NPPA and SLC12A1 1 0.01 0.42 0.07
10 INT257511 Regulation of Binding of Slc12a2 and Slc4a4 1 0.02 0.16 0.06
11 INT257510 Binding of Slc12a2 and Slc4a4 1 0.01 0.16 0.06
12 INT324343 SLC12A1 Regulation of Scr 1 0.00 0.25 0
13 INT212413 SLC12A1 Regulation of PRKAB1 1 0.00 0 0
14 INT324340 Binding of SLC12A1 and Scr 1 0.00 1.42 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for sodium:potassium:chloride symporter activity. They are ordered first by their pain relevance and then by number of times they were reported in sodium:potassium:chloride symporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT100115 Gene_expression of Slc12a2 34 0.76 39.15 15.69
2 INT91360 Negative_regulation of Slc12a2 16 0.54 10.46 12.89
3 INT127009 Positive_regulation of Phosphorylation of Slc12a2 5 0.70 5.3 9.9
4 INT127010 Phosphorylation of Slc12a2 6 0.82 4.68 9.66
5 INT62014 Negative_regulation of Slc12a2 17 0.49 12.85 8.99
6 INT138889 Positive_regulation of Slc12a2 23 0.65 18.53 8.85
7 INT127008 Positive_regulation of Slc12a2 2 0.70 4.73 7.61
8 INT94356 Regulation of Slc12a2 11 0.58 12.8 6.59
9 INT146488 Gene_expression of Slc12a2 16 0.73 4.63 5.11
10 INT244386 Positive_regulation of Gene_expression of Slc12a2 10 0.58 18.39 4.5
11 INT118644 Regulation of Slc12a2 5 0.45 2.43 3.6
12 INT244385 Phosphorylation of Slc12a2 12 0.77 4.67 2.74
13 INT138891 Regulation of Gene_expression of Slc12a2 5 0.58 4.83 2.64
14 INT127007 Positive_regulation of Positive_regulation of Slc12a2 2 0.70 1.42 2.46
15 INT247918 Positive_regulation of Positive_regulation of Slc12a2 1 0.39 2.55 1.86
16 INT210693 Positive_regulation of Gene_expression of Slc12a2 5 0.46 1.3 1.77
17 INT244392 Binding of Slc12a2 3 0.35 2.05 1.68
18 INT24863 Negative_regulation of SLC12A2 12 0.44 1.85 1.61
19 INT117710 Binding of Slc12a2 4 0.19 0.13 1.48
20 INT244393 Positive_regulation of Phosphorylation of Slc12a2 1 0.65 1.92 1.12
21 INT127004 Regulation of Phosphorylation of Slc12a2 1 0.54 0.35 1.1
22 INT149656 Negative_regulation of Gene_expression of Slc12a2 3 0.38 2.36 1.02
23 INT160022 Transcription of Slc12a2 2 0.53 0.75 0.97
24 INT11225 Positive_regulation of SLC12A2 3 0.45 1.1 0.6
25 INT50084 Positive_regulation of SLC12A1 4 0.03 1.11 0.57
26 INT160019 Regulation of Transcription of Slc12a2 1 0.26 0.41 0.46
27 INT328606 Regulation of Regulation of Slc12a2 1 0.10 0 0.42
28 INT24862 Negative_regulation of Negative_regulation of SLC12A2 1 0.23 0 0.33
29 INT100114 Localization of Slc12a2 3 0.73 2.02 0.31
30 INT244383 Transcription of Slc12a2 2 0.67 0.82 0.29
31 INT239793 Localization of SLC12A2 1 0.57 0.14 0.28
32 INT50948 Gene_expression of SLC12A2 6 0.59 4.55 0.22
33 INT244389 Negative_regulation of Positive_regulation of Slc12a2 1 0.40 0.4 0.2
34 INT50083 Binding of SLC12A1 2 0.01 1.01 0.15
35 INT50082 Positive_regulation of Binding of SLC12A1 1 0.02 0.3 0.15
36 INT165954 Gene_expression of SLC12A1 3 0.55 1.32 0.1
37 INT292542 Localization of Slc12a2 1 0.66 0 0.07
38 INT293109 Positive_regulation of Transcription of Slc12a2 1 0.10 0.35 0.05
39 INT239797 Regulation of SLC12A2 1 0.34 0.1 0.04
40 INT293100 Regulation of Positive_regulation of Slc12a2 1 0.08 0.19 0
41 INT338257 Negative_regulation of SLC12A1 1 0.01 0.38 0
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