GO:0008559

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Name xenobiotic-transporting ATPase activity
Categary Function
Go Slim No
Go Link GO:0008559
Unique Molecular Interactions 45
Total Molecular Interactions 54
Total Single Events 916
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for xenobiotic-transporting ATPase activity. They are ordered first by their pain relevance and then by number of times they were reported for xenobiotic-transporting ATPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT146930 CAP1 Regulation of ABCB1 1 0.29 0.3 2.19
2 INT154439 Ufm1 Positive_regulation of Gene_expression of Abcb1a 1 0.00 0 0.85
3 INT144283 ACP1 Positive_regulation of ABCB1 1 0.63 0.6 0.81
4 INT155220 ABCG2 Positive_regulation of Abcc2 1 0.23 0.54 0.76
5 INT106374 Olr833 Negative_regulation of Abcb1a 1 0.00 0 0.56
6 INT145726 Binding of Abcb1a and Alms1 1 0.32 0.48 0.56
7 INT335514 NR1I2 Regulation of Gene_expression of ABCB1 1 0.66 2.42 0.54
8 INT130312 Ccl4 Negative_regulation of Abcc3 1 0.33 0.28 0.48
9 INT130311 Ccl4 Positive_regulation of Abcc1 1 0.47 0.28 0.47
10 INT146087 Abcb1b Regulation of Binding of Abcb1a 1 0.49 0.09 0.34
11 INT146088 Abcb1b Regulation of Abcb1a 1 0.49 0.09 0.34
12 INT111837 Binding of ABCB1 and SLC22A3 1 0.35 0 0.31
13 INT138721 Abcc1 Regulation of Gene_expression of Abcc4 1 0.50 0 0.31
14 INT133325 Mod2 Negative_regulation of Gene_expression of Abcb1a 1 0.01 0.18 0.31
15 INT95968 OPRD1 Negative_regulation of Gene_expression of ABCB1 1 0.34 0.75 0.21
16 INT262178 Binding of Nr1i2 and Abcb1b 1 0.07 1.68 0.21
17 INT95969 OPRD1 Negative_regulation of ABCB1 1 0.34 0.75 0.21
18 INT112781 Abcc1 Regulation of Abcb1b 1 0.25 0 0.21
19 INT132897 Binding of ABCB1 and Slco1c1 1 0.03 0 0.2
20 INT121382 Casr Positive_regulation of Abcc3 1 0.32 0.25 0.19
21 INT121381 Casr Positive_regulation of Positive_regulation of Abcc3 1 0.30 0.25 0.19
22 INT138426 Abcb1b Regulation of Abcg2 1 0.29 0 0.17
23 INT113867 Binding of ABCB1 and PGP 1 0.46 1 0.16
24 INT137510 Nfkb1 Positive_regulation of Gene_expression of ABCB1 1 0.17 0.59 0.14
25 INT262148 Positive_regulation of Nr1i2 Positive_regulation of Abcb1b 1 0.09 0.69 0.12
26 INT100479 Binding of Abcb1b and Camk1d 1 0.44 0 0.12
27 INT54470 Binding of DNAH8 and ABCB1 1 0.30 0 0.1
28 INT54471 Positive_regulation of Binding of DNAH8 and ABCB1 1 0.29 0 0.1
29 INT99910 Binding of MTX1 and ABCB1 1 0.25 0.09 0.1
30 INT99476 Binding of CYP3A4 and ABCB1 2 0.28 0 0.08
31 INT177294 Binding of ABCB1 and TNFRSF25 1 0.16 0 0.08
32 INT159274 Tsiq1 Positive_regulation of Abcb1a 1 0.00 0.14 0.07
33 INT177295 Binding of CXADR and ABCB1 1 0.30 0 0.05
34 INT177272 Binding of ABCB1 and NR1H4 1 0.02 0 0.04
35 INT241536 Binding of Abcb1b and Abcg2 1 0.10 0.17 0.04
36 INT197713 CNTN2 Positive_regulation of ABCB1 1 0.01 0.34 0
37 INT276759 ABCB1 Regulation of TOP2A 1 0.04 0.61 0
38 INT97565 JUN Positive_regulation of Gene_expression of ABCB1 1 0.45 0.06 0
39 INT177256 SV2A Positive_regulation of ABCB1 1 0.38 0 0
40 INT177287 CXADR Positive_regulation of ABCB1 1 0.39 0 0
41 INT321530 Ubp1 Regulation of Abcb1b 1 0.43 0.06 0
42 INT277863 Binding of ERBB2 and Abcc3 1 0.01 0.28 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for xenobiotic-transporting ATPase activity. They are ordered first by their pain relevance and then by number of times they were reported in xenobiotic-transporting ATPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT90300 Gene_expression of Abcb1a 56 0.78 11.05 22.89
2 INT52457 Gene_expression of ABCB1 129 0.78 38.68 19.88
3 INT73362 Negative_regulation of Abcb1a 46 0.59 8.78 17.81
4 INT83682 Positive_regulation of Abcb1a 22 0.68 3.3 15.6
5 INT7776 Gene_expression of Abcb1b 63 0.75 21.35 14.92
6 INT102731 Regulation of ABCB1 29 0.62 5.36 11.67
7 INT54473 Binding of ABCB1 30 0.48 8.65 10.38
8 INT13467 Positive_regulation of ABCB1 36 0.68 9.68 8.95
9 INT82839 Negative_regulation of ABCB1 61 0.59 16.09 8.83
10 INT80981 Regulation of Abcb1a 19 0.62 1.86 7.2
11 INT54617 Positive_regulation of Gene_expression of Abcb1b 22 0.67 9.8 5.34
12 INT96198 Positive_regulation of Gene_expression of ABCB1 25 0.68 5.89 5.15
13 INT119909 Binding of Abcb1a 10 0.36 0.76 5.07
14 INT110202 Positive_regulation of Gene_expression of Abcb1a 13 0.67 2.08 5.01
15 INT130300 Gene_expression of Abcc3 14 0.70 5.34 4.96
16 INT56122 Positive_regulation of Abcc3 7 0.47 2.25 4.9
17 INT106131 Negative_regulation of Abcc3 8 0.58 3.17 4.86
18 INT60957 Negative_regulation of Abcb1b 18 0.57 6 4.73
19 INT80983 Regulation of Abcb1b 16 0.60 1.95 4.32
20 INT117828 Regulation of Gene_expression of Abcb1b 7 0.60 1.8 3.76
21 INT122448 Regulation of Gene_expression of ABCB1 13 0.62 3.67 3.5
22 INT95971 Negative_regulation of Gene_expression of ABCB1 7 0.58 5.61 3.34
23 INT70563 Localization of ABCB1 14 0.78 2.03 3.09
24 INT119238 Positive_regulation of Positive_regulation of Abcb1a 5 0.40 1.14 3.09
25 INT147159 Regulation of Gene_expression of Abcc3 4 0.55 2.96 2.97
26 INT131124 Localization of Abcc3 4 0.75 0.48 2.73
27 INT145270 Gene_expression of ABCG2 19 0.75 7.87 2.69
28 INT90299 Negative_regulation of Gene_expression of Abcb1a 4 0.43 0.54 2.65
29 INT40315 Gene_expression of Abcc1 10 0.76 5.66 2.53
30 INT118114 Negative_regulation of ABCG2 5 0.57 2.52 2.47
31 INT135396 Regulation of Gene_expression of Abcb1a 7 0.60 0.69 2.28
32 INT145274 Positive_regulation of ABCG2 5 0.67 3.46 2.24
33 INT60956 Binding of Abcb1b 8 0.47 2.49 2.09
34 INT112779 Positive_regulation of Abcc1 2 0.50 0.63 1.95
35 INT115665 Transcription of ABCB1 9 0.71 3.69 1.91
36 INT78352 Localization of Abcb1a 4 0.68 1.44 1.52
37 INT145273 Transcription of ABCG2 2 0.69 1.72 1.25
38 INT147162 Positive_regulation of Abcb1b 13 0.57 7.29 1.15
39 INT131127 Localization of ABCG2 1 0.02 0.26 1.03
40 INT130748 Negative_regulation of Localization of ABCB1 2 0.42 0.71 1.02
41 INT130301 Positive_regulation of Gene_expression of Abcc3 2 0.63 0.52 1
42 INT130297 Positive_regulation of Gene_expression of Abcc1 3 0.56 1.06 0.97
43 INT145271 Positive_regulation of Gene_expression of ABCG2 5 0.49 3.97 0.9
44 INT135398 Transcription of Abcb1a 2 0.55 1.53 0.89
45 INT135399 Regulation of Positive_regulation of Abcb1a 1 0.49 0 0.73
46 INT135397 Positive_regulation of Regulation of Abcb1a 1 0.37 0 0.71
47 INT147160 Transcription of Abcc3 2 0.42 0.95 0.66
48 INT133322 Positive_regulation of Localization of Abcb1a 1 0.14 0.41 0.44
49 INT133324 Negative_regulation of Localization of Abcb1a 1 0.12 0.41 0.44
50 INT199422 Positive_regulation of Negative_regulation of ABCB1 2 0.49 1.28 0.4
51 INT80980 Regulation of Regulation of Abcb1a 1 0.45 0 0.32
52 INT80982 Regulation of Regulation of Abcb1b 1 0.60 0 0.32
53 INT126674 Binding of ABCG2 1 0.36 0.1 0.28
54 INT307279 Positive_regulation of Localization of ABCB1 1 0.05 0 0.25
55 INT143805 Positive_regulation of Negative_regulation of Abcc3 1 0.37 0 0.25
56 INT164327 Regulation of Gene_expression of ABCG2 1 0.04 0.34 0.22
57 INT250673 Negative_regulation of Gene_expression of Abcb1b 2 0.42 1.66 0.19
58 INT83679 Positive_regulation of Binding of ABCB1 1 0.67 0 0.16
59 INT246624 Binding of Abcc3 2 0.00 0.59 0.15
60 INT134255 Localization of Abcb1b 1 0.78 0 0.13
61 INT295162 Transcription of Abcb1b 4 0.59 1.69 0.11
62 INT285348 Negative_regulation of Negative_regulation of Abcb1a 1 0.28 0.28 0.11
63 INT60955 Positive_regulation of Negative_regulation of Abcb1b 1 0.30 0.23 0.1
64 INT139832 Regulation of Negative_regulation of ABCB1 1 0.44 0 0.08
65 INT321528 Positive_regulation of Transcription of Abcb1b 1 0.41 0.21 0.04
66 INT311750 Positive_regulation of Positive_regulation of ABCB1 1 0.68 0.13 0.03
67 INT115664 Positive_regulation of Transcription of ABCB1 3 0.37 0.54 0
68 INT104184 Negative_regulation of Negative_regulation of ABCB1 2 0.38 0 0
69 INT165323 Negative_regulation of Transcription of ABCB1 2 0.58 0.62 0
70 INT250679 Regulation of Positive_regulation of Abcb1b 1 0.26 0.47 0
71 INT311749 Regulation of Binding of ABCB1 1 0.44 0 0
72 INT321523 Negative_regulation of Binding of Abcb1b 1 0.35 0 0
73 INT252201 Phosphorylation of ABCB1 1 0.61 0 0
74 INT256747 Regulation of ABCG2 1 0.01 0.25 0
75 INT256250 Negative_regulation of Regulation of Abcc3 1 0.20 0.68 0
76 INT187890 Negative_regulation of Abcc1 1 0.25 0.06 0
77 INT63497 Protein_catabolism of ABCB1 1 0.24 0.22 0
78 INT256253 Regulation of Abcc3 1 0.21 0.68 0
79 INT321527 Regulation of Transcription of Abcb1b 1 0.51 0.14 0
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