GO:0008584

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Name male gonad development
Categary Process
Go Slim No
Go Link GO:0008584
Unique Molecular Interactions 1087
Total Molecular Interactions 1420
Total Single Events 15536
Pain Genes Associated 86

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for male gonad development. They are ordered first by their pain relevance and then by number of times they were reported for male gonad development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
2 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
3 INT113572 Binding of DMRT1 and OPRM1 1 0.01 0 1.9
4 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
5 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
6 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
7 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
8 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
9 INT348380 Binding of Fdps and Lpar5 1 0.07 1.45 1.25
10 INT25026 PLOD1 Regulation of FSHR 4 0.19 0.38 1.15
11 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11
12 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
13 INT30135 S100A9 Positive_regulation of REN 1 0.32 0.32 1
14 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
15 INT137920 Binding of Kdr and Oprm1 1 0.23 0 0.97
16 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
17 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
18 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
19 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91
20 INT48341 Negative_regulation of Pde8a Regulation of Ahsg 1 0.22 0 0.9
21 INT48342 Pde8a Regulation of Ahsg 1 0.24 0 0.9
22 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
23 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
24 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
25 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85
26 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
27 INT97056 Cpz Regulation of Gene_expression of Bcl2l1 1 0.22 0.57 0.83
28 INT33464 Binding of DMRT1 and Penk 1 0.28 0.16 0.81
29 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 0.09 0.61 0.81
30 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
31 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
32 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
33 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
34 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
35 INT39091 Negative_regulation of Penk Positive_regulation of Localization of Ren 1 0.30 0 0.74
36 INT39095 Negative_regulation of Agt Positive_regulation of Localization of Ren 1 0.38 0 0.73
37 INT101675 Bcl2l11 Regulation of Localization of Ggh 1 0.03 0 0.72
38 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
39 INT348396 Binding of LPAR5 and Fdps 1 0.07 0.81 0.69
40 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
41 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
42 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
43 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
44 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
45 INT348381 Fdps Positive_regulation of Lpar5 1 0.07 0.75 0.64
46 INT348399 Fdps Positive_regulation of LPAR5 1 0.08 0.75 0.64
47 INT83800 Aap Regulation of Gene_expression of Bcl2l1 1 0.28 0.58 0.64
48 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
49 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
50 INT35159 FSHR Regulation of PRL 2 0.34 0 0.6
51 INT60537 Gnrh1 Positive_regulation of Localization of FSHR 1 0.00 0.19 0.6
52 INT60538 Gnrh1 Positive_regulation of Localization of LHB 1 0.00 0.19 0.59
53 INT251161 Binding of Trpv1 and Rxfp2 1 0.06 0.18 0.55
54 INT129270 Binding of Wnt4 and Efs 1 0.00 0 0.55
55 INT54584 GNRH1 Positive_regulation of FSHR 3 0.48 2.02 0.54
56 INT330544 Bcl2l11 Negative_regulation of Prkcg 1 0.03 0.38 0.52
57 INT330553 Bcl2l11 Negative_regulation of Camk2a 1 0.01 0.38 0.52
58 INT330541 Bcl2l11 Negative_regulation of Negative_regulation of Prkcg 1 0.03 0.38 0.52
59 INT330545 Bcl2l11 Negative_regulation of Trib3 1 0.00 0.38 0.52
60 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
61 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
62 INT118485 CST3 Regulation of CTSH 1 0.36 0 0.49
63 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
64 INT8317 Fshr Regulation of Localization of LH 1 0.29 0 0.48
65 INT237154 LGALS4 Positive_regulation of KIT 1 0.10 1.99 0.47
66 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
67 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
68 INT113573 Binding of DMRT1 and FAIM3 1 0.04 0 0.47
69 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
70 INT39178 NPL Regulation of FSHR 1 0.03 0 0.46
71 INT20761 INHBA Regulation of Localization of GNRH1 1 0.02 0 0.46
72 INT151456 Binding of KITLG and Insrr 1 0.00 0.21 0.46
73 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
74 INT39142 ras Positive_regulation of REN 1 0.01 1.34 0.45
75 INT116926 Cpox Regulation of AKR1C3 1 0.01 0.28 0.45
76 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
77 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
78 INT39143 ras Positive_regulation of Gene_expression of REN 1 0.01 1.35 0.45
79 INT252425 Positive_regulation of AR Positive_regulation of Gene_expression of CXCL10 1 0.00 0.9 0.44
80 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
81 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
82 INT142273 KITLG Positive_regulation of Gene_expression of Tnf 1 0.07 0.9 0.43
83 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
84 INT25027 CRH Negative_regulation of Negative_regulation of FSHR 1 0.25 0 0.42
85 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
86 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
87 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42
88 INT76153 Binding of NCOR2 and Negative_regulation of Localization of LHB 1 0.00 0 0.42
89 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
90 INT139047 Negative_regulation of AR Negative_regulation of Positive_regulation of CPOX 1 0.07 0.76 0.4
91 INT148246 Binding of KITLG and Positive_regulation of Kit 1 0.04 0.43 0.38
92 INT117361 Binding of Esr1 and sea 1 0.02 1.38 0.38
93 INT148247 KITLG Positive_regulation of Kit 1 0.03 0.43 0.38
94 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
95 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
96 INT175016 Binding of REN and S100A6 2 0.11 1.13 0.37
97 INT39093 Negative_regulation of Prss12 Positive_regulation of Localization of Ren 1 0.10 0 0.37
98 INT117359 Binding of Esr1 and Wbc1 1 0.00 1.38 0.37
99 INT39094 Negative_regulation of Nts Positive_regulation of Localization of Ren 1 0.16 0 0.37
100 INT39096 Prss12 Negative_regulation of Ren 1 0.12 0 0.37
101 INT60817 Binding of Sstr1 and Bcl2l11 1 0.06 0 0.37
102 INT39092 Agt Negative_regulation of Ren 1 0.39 0 0.37
103 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
104 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35
105 INT187064 ARSD Negative_regulation of CYP19A1 1 0.22 0.7 0.35
106 INT252453 Binding of AR and Adora2b 1 0.05 0 0.35
107 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
108 INT337156 Kdr Positive_regulation of Gtf3a 1 0.01 0.77 0.35
109 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
110 INT12522 Binding of FSHR and POMC 1 0.33 3.89 0.34
111 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
112 INT27848 Calca Positive_regulation of Localization of Ren 1 0.39 0.06 0.34
113 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
114 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33
115 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
116 INT122169 AKR1C3 Regulation of PPARG 1 0.45 0.26 0.33
117 INT75641 AR Positive_regulation of Positive_regulation of EIF2B3 1 0.02 0 0.33
118 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32
119 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.97 0.32
120 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32
121 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
122 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32
123 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
124 INT31044 Gnrh1 Negative_regulation of Localization of FSHR 1 0.04 0 0.32
125 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31
126 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31
127 INT31040 Ghrh Positive_regulation of Localization of FSHR 1 0.05 0 0.31
128 INT28688 Binding of Kng1 and Ctsl1 1 0.15 0 0.31
129 INT99843 Edn3 Negative_regulation of Localization of Ren 1 0.25 0.42 0.31
130 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31
131 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31
132 INT31041 Ghrh Positive_regulation of FSHR 1 0.05 0 0.31
133 INT40219 Ang Negative_regulation of REN 1 0.00 0 0.3
134 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
135 INT156087 Binding of AKR1C3 and Akr1c1 1 0.05 0.31 0.3
136 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
137 INT309156 Esr1 Regulation of Gene_expression of Dlat 1 0.05 1.06 0.3
138 INT156083 Binding of AKR1C2 and AKR1C3 1 0.05 0.31 0.3
139 INT97549 KITLG Negative_regulation of Mc1r 1 0.01 0.15 0.3
140 INT156084 Binding of PTGS2 and AKR1C3 1 0.02 0.31 0.3
141 INT39033 Hrh1 Positive_regulation of Localization of Ren 1 0.00 0.29 0.3
142 INT156082 Binding of PTGS1 and AKR1C3 1 0.01 0.31 0.3
143 INT35080 CRH Negative_regulation of Localization of FSHR 1 0.03 0 0.29
144 INT175017 Negative_regulation of Binding of REN and S100A6 1 0.13 0.45 0.29
145 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
146 INT89895 LHB Positive_regulation of Localization of PRL 1 0.09 0 0.29
147 INT89901 LHB Positive_regulation of Localization of GH1 1 0.03 0 0.29
148 INT89913 LHB Positive_regulation of Localization of POMC 1 0.10 0 0.29
149 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29
150 INT175018 Positive_regulation of Binding of REN and S100A6 1 0.15 0.45 0.29
151 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
152 INT134927 CYP19A1 Positive_regulation of Gene_expression of MME 1 0.30 1.04 0.28
153 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
154 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
155 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
156 INT337162 Binding of Kdr and Iqgap1 1 0.32 0.98 0.28
157 INT134930 MME Positive_regulation of Gene_expression of CYP19A1 1 0.30 1.04 0.28
158 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
159 INT172901 Binding of Bad and Bcl2l1 3 0.13 6.51 0.27
160 INT288497 Binding of Tlr7 and Tlr9 1 0.21 0.97 0.27
161 INT191497 Binding of REN and NLRP3 1 0.02 0.55 0.27
162 INT137167 Binding of IFNG and TLR3 1 0.24 0.32 0.27
163 INT131357 Agtr2 Regulation of Ren 1 0.04 0.88 0.27
164 INT44441 GNRH1 Positive_regulation of Localization of FSHR 2 0.15 0.86 0.26
165 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
166 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
167 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
168 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
169 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
170 INT156587 Hst1 Negative_regulation of Gene_expression of Cpox 1 0.15 0.82 0.26
171 INT156589 Hst1 Negative_regulation of Mpo 1 0.41 0.95 0.26
172 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26
173 INT223042 AR Positive_regulation of ADCY1 1 0.01 0.41 0.25
174 INT317773 Positive_regulation of GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
175 INT317775 GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
176 INT118418 Gata1 Positive_regulation of Transcription of Tac2 1 0.61 0.77 0.25
177 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
178 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25
179 INT182349 Binding of Ms4a1 and Esr1 1 0.04 1.26 0.25
180 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
181 INT118419 Binding of Gata1 and Tac2 1 0.31 0.7 0.24
182 INT257776 Phosphorylation of AR Positive_regulation of Localization of TAB2 1 0.26 0.38 0.24
183 INT252427 IGKV2D-29 Regulation of Gene_expression of AR 1 0.02 0 0.24
184 INT309160 Binding of Esr1 and Edc4 1 0.03 0.34 0.24
185 INT8303 Fshr Regulation of Localization of Gnrh1 1 0.16 0 0.24
186 INT89469 Fk Positive_regulation of Gene_expression of Lhcgr 1 0.01 0 0.24
187 INT8299 Fshr Regulation of Grp 1 0.10 0 0.23
188 INT14642 PENK Positive_regulation of REN 1 0.72 0.19 0.23
189 INT139046 Negative_regulation of AR Negative_regulation of Phosphorylation of DYT10 1 0.33 0.34 0.23
190 INT139050 Negative_regulation of AR Negative_regulation of Phosphorylation of PRKCB 1 0.02 0.34 0.23
191 INT14643 PENK Positive_regulation of Positive_regulation of REN 1 0.48 0.19 0.23
192 INT8321 Fshr Regulation of Grpr 1 0.09 0 0.23
193 INT139045 Negative_regulation of AR Negative_regulation of CPOX 1 0.07 0.34 0.23
194 INT139048 Negative_regulation of AR Negative_regulation of Positive_regulation of TRAF3IP2 1 0.02 0.34 0.23
195 INT8322 Fshr Regulation of Rgn 1 0.01 0 0.23
196 INT139049 Negative_regulation of AR Negative_regulation of Positive_regulation of DYT10 1 0.33 0.34 0.23
197 INT323436 VEGFA Regulation of Kdr 1 0.03 0.77 0.23
198 INT284433 Kdm5d Regulation of KITLG 1 0.00 0.57 0.23
199 INT89470 CGA Regulation of Gene_expression of Lhcgr 1 0.00 0 0.23
200 INT89468 Fk Regulation of Gene_expression of Lhcgr 1 0.01 0 0.23

Single Events

The table below shows the top 100 pain related interactions that have been reported for male gonad development. They are ordered first by their pain relevance and then by number of times they were reported in male gonad development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
2 INT46 Localization of Ren 233 0.81 46.15 62.44
3 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56
4 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
5 INT654 Localization of REN 250 0.81 75.12 47.86
6 INT375 Positive_regulation of REN 293 0.70 152.46 47.55
7 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
8 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
9 INT49 Negative_regulation of Ren 129 0.59 37.48 35.62
10 INT1116 Regulation of Ren 103 0.62 27.66 33.26
11 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
12 INT50 Negative_regulation of Localization of Ren 87 0.59 14.94 30.22
13 INT660 Negative_regulation of REN 194 0.59 82.06 29.46
14 INT37296 Binding of Esr1 117 0.43 62.51 27.33
15 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
16 INT2140 Regulation of REN 104 0.62 28.24 24.49
17 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
18 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39
19 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21
20 INT1644 Regulation of FSHR 77 0.55 15.62 21.49
21 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
22 INT5372 Localization of LHB 55 0.68 9.47 19
23 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
24 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26
25 INT48 Positive_regulation of Localization of Ren 69 0.70 12.47 18.03
26 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
27 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
28 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
29 INT653 Negative_regulation of Localization of REN 67 0.59 20.33 16.7
30 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
31 INT912 Localization of FSHR 91 0.79 23.61 15.58
32 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33
33 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
34 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
35 INT655 Positive_regulation of Localization of REN 86 0.70 32.41 13.56
36 INT2038 Localization of Esr1 104 0.79 40.12 13.27
37 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
38 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04
39 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
40 INT481 Regulation of Localization of Ren 37 0.62 5.95 11.61
41 INT661 Gene_expression of REN 100 0.78 48.21 11.36
42 INT9946 Regulation of Localization of LHB 27 0.52 2.47 11.08
43 INT1180 Gene_expression of Ren 63 0.77 27.33 10.51
44 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
45 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09
46 INT92493 Gene_expression of Fdps 19 0.75 11.28 10.08
47 INT1372 Regulation of Localization of REN 50 0.62 5.76 9.81
48 INT1648 Regulation of LHB 21 0.61 3.32 9.6
49 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
50 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
51 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21
52 INT10597 Gene_expression of Cyp19a1 27 0.78 7.48 9.11
53 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95
54 INT35366 Binding of AR 87 0.47 30.52 8.9
55 INT1647 Negative_regulation of FSHR 54 0.45 13.44 8.87
56 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
57 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
58 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34
59 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
60 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
61 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
62 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
63 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
64 INT83531 Gene_expression of KITLG 54 0.65 26 7.07
65 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
66 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
67 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
68 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
69 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
70 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
71 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
72 INT677 Positive_regulation of CST3 20 0.67 17.47 6
73 INT135760 Regulation of Gene_expression of Cyp19a1 2 0.62 1.15 5.81
74 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
75 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
76 INT2613 Negative_regulation of Positive_regulation of Ren 16 0.59 8.2 5.62
77 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
78 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37
79 INT213741 Gene_expression of Kdr 60 0.75 44.24 5.35
80 INT145929 Regulation of Bax 20 0.60 18.12 5.35
81 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32
82 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
83 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16
84 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
85 INT924 Regulation of Localization of FSHR 15 0.45 1.4 5.07
86 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
87 INT99091 Regulation of AR 70 0.45 31.68 5.05
88 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
89 INT923 Positive_regulation of Localization of FSHR 14 0.43 2.48 4.96
90 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
91 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
92 INT5205 Localization of AR 43 0.80 12.87 4.63
93 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
94 INT9729 Negative_regulation of LHB 14 0.42 1.86 4.63
95 INT37139 Negative_regulation of Fdps 9 0.38 4.33 4.46
96 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
97 INT3097 Binding of Ren 12 0.48 3.15 4.4
98 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33
99 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
100 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28
101 INT83798 Negative_regulation of Gene_expression of Bcl2l1 28 0.58 20.26 4.21
102 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
103 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
104 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
105 INT75688 Binding of KITLG 24 0.30 11.73 4.06
106 INT83796 Regulation of Gene_expression of Bcl2l1 10 0.61 7.85 4.05
107 INT11370 Positive_regulation of LHB 15 0.28 5.45 4.01
108 INT123752 Regulation of Bax 19 0.60 16.45 4
109 INT108086 Negative_regulation of AKR1C3 17 0.58 7.7 3.99
110 INT112692 Localization of Bax 31 0.80 20.97 3.98
111 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95
112 INT95423 Negative_regulation of Bcl2l1 26 0.41 21.66 3.81
113 INT99889 Transcription of SRD5A1 5 0.71 1.45 3.74
114 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
115 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
116 INT20461 Binding of Esr1 34 0.48 9.58 3.66
117 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61
118 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56
119 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53
120 INT1646 Negative_regulation of Localization of FSHR 17 0.58 7.36 3.46
121 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
122 INT127111 Regulation of Inhba 5 0.60 2.85 3.28
123 INT4479 Negative_regulation of Positive_regulation of REN 17 0.56 6.1 3.27
124 INT33463 Binding of DMRT1 3 0.31 0.16 3.27
125 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
126 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
127 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
128 INT86245 Positive_regulation of Bcl2l1 15 0.46 12.67 3.11
129 INT34977 Gene_expression of Hmga2 11 0.76 12.39 3.07
130 INT116376 Transcription of Cyp19a1 2 0.40 0.74 3.04
131 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01
132 INT111820 Positive_regulation of Fdps 10 0.42 10.63 3.01
133 INT105884 Binding of Bcl2 19 0.35 15.67 3
134 INT1177 Positive_regulation of Positive_regulation of Ren 16 0.70 6.11 3
135 INT133809 Negative_regulation of Gene_expression of CYP19A1 9 0.43 7.67 2.99
136 INT113277 Positive_regulation of Gene_expression of CYP19A1 13 0.69 10.23 2.97
137 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96
138 INT99574 Positive_regulation of KITLG 10 0.39 6.74 2.96
139 INT11371 Positive_regulation of Localization of LHB 8 0.47 1.4 2.93
140 INT16015 Negative_regulation of Localization of LHB 10 0.37 2.95 2.9
141 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89
142 INT4147 Gene_expression of LHB 8 0.49 3.94 2.88
143 INT179867 Localization of Fdps 7 0.63 3.62 2.86
144 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
145 INT24279 Gene_expression of INSL3 11 0.75 12.46 2.8
146 INT78146 Gene_expression of AKR1C3 24 0.77 5.71 2.77
147 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71
148 INT156016 Binding of BCL2L1 10 0.36 7.42 2.64
149 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
150 INT1815 Positive_regulation of Negative_regulation of Ren 6 0.47 1.32 2.54
151 INT185927 Positive_regulation of Positive_regulation of AR 12 0.34 6.35 2.5
152 INT127108 Gene_expression of Inhba 12 0.65 3.21 2.48
153 INT1178 Positive_regulation of Gene_expression of Ren 16 0.60 7.71 2.41
154 INT86147 Positive_regulation of Inhba 8 0.63 1.94 2.39
155 INT27835 Regulation of Positive_regulation of Ren 10 0.44 2.27 2.38
156 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
157 INT126473 Regulation of KITLG 5 0.14 7.86 2.34
158 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
159 INT134626 Positive_regulation of Gene_expression of Kdr 20 0.63 14.63 2.29
160 INT184932 Binding of Sry 1 0.31 2.57 2.28
161 INT97748 Positive_regulation of BCL2L1 12 0.67 9.83 2.26
162 INT640 Regulation of CST3 9 0.60 4.04 2.26
163 INT4588 Positive_regulation of Regulation of Ren 4 0.47 1.24 2.26
164 INT91836 Negative_regulation of Gene_expression of BCL2L1 9 0.49 8.59 2.25
165 INT71048 Transcription of CYP19A1 11 0.72 8.74 2.24
166 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
167 INT83799 Phosphorylation of Bcl2l1 8 0.82 7.86 2.23
168 INT102752 Positive_regulation of Gene_expression of BCL2L1 14 0.67 13.8 2.19
169 INT85085 Positive_regulation of KIT 36 0.53 30.08 2.17
170 INT3533 Binding of REN 24 0.37 10.84 2.16
171 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15
172 INT111113 Binding of CYP19A1 15 0.36 9.17 2.12
173 INT27989 Positive_regulation of Gene_expression of REN 18 0.55 12.69 2.11
174 INT154970 Localization of Bax 15 0.74 11.12 2.11
175 INT342803 Positive_regulation of Transcription of Cyp19a1 1 0.30 0.33 2.08
176 INT101645 Regulation of Gene_expression of Bcl2l1 8 0.36 5.27 2.05
177 INT342815 Positive_regulation of Transcription of SRD5A1 1 0.49 0.33 2.04
178 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
179 INT98836 Transcription of Bax 6 0.69 5.04 1.96
180 INT149761 Negative_regulation of MAS1 5 0.29 1.91 1.95
181 INT81347 Regulation of Cyp19a1 7 0.40 2.1 1.94
182 INT228129 Negative_regulation of Bcl2l11 10 0.58 11.08 1.93
183 INT107905 Gene_expression of BCL2L11 9 0.75 7.58 1.92
184 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92
185 INT134442 Transcription of Bax 14 0.67 7.6 1.9
186 INT17399 Positive_regulation of Positive_regulation of REN 13 0.69 7.05 1.9
187 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
188 INT153684 Negative_regulation of Bcl2l11 3 0.31 1.19 1.89
189 INT14500 Positive_regulation of Gene_expression of CST3 9 0.67 7.46 1.87
190 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
191 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
192 INT68857 Positive_regulation of Rxfp2 5 0.34 1.51 1.86
193 INT134443 Binding of Bax 10 0.47 5.62 1.84
194 INT104912 Gene_expression of Acvr2a 8 0.63 4.48 1.81
195 INT162725 Binding of Kdr 13 0.42 8.86 1.79
196 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
197 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
198 INT64378 Gene_expression of DMRT1 9 0.54 1.72 1.71
199 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7
200 INT314189 Positive_regulation of Phosphorylation of Nr5a1 1 0.02 2.16 1.7
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