GO:0008585

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Name female gonad development
Categary Process
Go Slim No
Go Link GO:0008585
Unique Molecular Interactions 85
Total Molecular Interactions 119
Total Single Events 920
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for female gonad development. They are ordered first by their pain relevance and then by number of times they were reported for female gonad development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT25026 PLOD1 Regulation of FSHR 4 0.19 0.38 1.15
2 INT280949 Binding of Fst and Inhbe 3 0.01 2.51 1.15
3 INT167819 IFNA1 Positive_regulation of Fst 1 0.39 0 1.07
4 INT146897 Binding of Fst and OR13H1 1 0.01 0 1.05
5 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
6 INT137102 Fst Regulation of Sec22b 1 0.07 0 0.67
7 INT137101 Fst Regulation of Htr1a 1 0.24 0 0.67
8 INT35159 FSHR Regulation of PRL 2 0.34 0 0.6
9 INT60537 Gnrh1 Positive_regulation of Localization of FSHR 1 0.00 0.19 0.6
10 INT144320 Binding of Fst and Rbm39 1 0.04 0 0.59
11 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57
12 INT129270 Binding of Wnt4 and Efs 1 0.00 0 0.55
13 INT54584 GNRH1 Positive_regulation of FSHR 3 0.48 2.02 0.54
14 INT39178 NPL Regulation of FSHR 1 0.03 0 0.46
15 INT25027 CRH Negative_regulation of Negative_regulation of FSHR 1 0.25 0 0.42
16 INT12522 Binding of FSHR and POMC 1 0.33 3.89 0.34
17 INT31044 Gnrh1 Negative_regulation of Localization of FSHR 1 0.04 0 0.32
18 INT31040 Ghrh Positive_regulation of Localization of FSHR 1 0.05 0 0.31
19 INT31041 Ghrh Positive_regulation of FSHR 1 0.05 0 0.31
20 INT35080 CRH Negative_regulation of Localization of FSHR 1 0.03 0 0.29
21 INT44441 GNRH1 Positive_regulation of Localization of FSHR 2 0.15 0.86 0.26
22 INT212568 Fst Regulation of Gene_expression of Il2 1 0.30 0.07 0.24
23 INT89469 Fk Positive_regulation of Gene_expression of Lhcgr 1 0.01 0 0.24
24 INT89470 CGA Regulation of Gene_expression of Lhcgr 1 0.00 0 0.23
25 INT89468 Fk Regulation of Gene_expression of Lhcgr 1 0.01 0 0.23
26 INT35162 GH1 Regulation of FSHR 1 0.17 0 0.21
27 INT35161 FSHR Regulation of LHB 1 0.18 0 0.21
28 INT35153 FSHR Regulation of GHRH 1 0.04 0 0.21
29 INT35156 FSHR Regulation of PGR 1 0.18 0 0.21
30 INT25052 Crh Regulation of FSHR 1 0.08 0 0.19
31 INT25054 Crh Negative_regulation of FSHR 1 0.07 0 0.17
32 INT65677 Binding of CGA and FSHR 2 0.25 0.29 0.16
33 INT350713 MIR219-1 Negative_regulation of Pdgfra 1 0.00 0.4 0.15
34 INT200326 Hdac1 Negative_regulation of Lhcgr 1 0.03 0 0.12
35 INT200318 Hdac1 Negative_regulation of Transcription of Lhcgr 1 0.03 0 0.12
36 INT200346 Hdac2 Negative_regulation of Lhcgr 1 0.04 0 0.12
37 INT200347 Hdac2 Negative_regulation of Transcription of Lhcgr 1 0.04 0 0.12
38 INT284891 FSHR Positive_regulation of Gene_expression of PLOD1 2 0.03 1.32 0.11
39 INT147936 CGA Regulation of Gene_expression of FSHR 1 0.31 0.71 0.1
40 INT12523 Binding of FSHR and LHB 1 0.11 0.98 0.09
41 INT12520 Binding of FSHR and GANAB 1 0.03 0.97 0.09
42 INT222511 Il1a Positive_regulation of Gene_expression of Fst 1 0.01 0.32 0.08
43 INT222431 Tlr4 Positive_regulation of Gene_expression of Fst 1 0.01 0.29 0.06
44 INT222463 Inhba Positive_regulation of Gene_expression of Fst 1 0.01 0 0.05
45 INT222520 Mzb1 Positive_regulation of Gene_expression of Fst 1 0.04 0 0.05
46 INT222476 Gnrh1 Negative_regulation of Gene_expression of Fst 1 0.04 0 0.05
47 INT263431 Trib3 Regulation of Pdgfra 1 0.00 0 0.04
48 INT263428 Abl1 Regulation of Pdgfra 1 0.00 0 0.04
49 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03
50 INT340558 Gene_expression of Fst Positive_regulation of Akt1 1 0.09 0.41 0.03
51 INT350114 Positive_regulation of GNRH1 Positive_regulation of FSHR 1 0.05 0.86 0.03
52 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0
53 INT313597 Binding of BRCA2 and TOX3 1 0.11 0.7 0
54 INT187677 Negative_regulation of FSHR Positive_regulation of DBT 1 0.03 0 0
55 INT350120 FSHR Regulation of CYP19A1 1 0.01 3.02 0
56 INT314742 Binding of RAD51 and Brca2 1 0.06 1.05 0
57 INT290217 Binding of ZFP42 and TRIML2 1 0.31 0.28 0
58 INT234182 Binding of BRCA2 and PALB2 1 0.41 1.43 0
59 INT293982 MYC Negative_regulation of SFRP1 1 0.21 0.62 0
60 INT350117 GNRHR Negative_regulation of Localization of FSHR 1 0.01 1.06 0
61 INT187674 FSHR Positive_regulation of Gene_expression of CYP19A1 1 0.24 0 0
62 INT25051 Crh Negative_regulation of Localization of FSHR 1 0.07 0 0
63 INT350116 FSHR Positive_regulation of Gene_expression of CGA 1 0.01 1.28 0
64 INT284892 AMH Regulation of Localization of FSHR 1 0.01 0.18 0
65 INT356140 Fshb Regulation of FSHR 1 0.04 0.28 0
66 INT44233 Binding of FSHR and TRH 1 0.34 0.9 0
67 INT334917 GNRHR Positive_regulation of Gene_expression of FSHR 1 0.05 0.53 0
68 INT270758 GNRHR Positive_regulation of Localization of FSHR 1 0.08 0.68 0
69 INT260074 Binding of BRCA2 and PTCH1 1 0.40 0.15 0
70 INT176569 Binding of FSHR and Cyp19a1 1 0.04 0.06 0
71 INT290213 Binding of ZFP42 and TRIML1 1 0.36 0.28 0
72 INT295432 FSHR Positive_regulation of PCOS1 1 0.06 1.24 0
73 INT315194 Binding of SFRP1 and Slc10a1 1 0.02 8.85 0
74 INT187669 FSHR Positive_regulation of DBT 1 0.03 0 0
75 INT350122 GNRH1 Negative_regulation of Localization of FSHR 1 0.05 0.99 0
76 INT295572 Binding of Fst and Mstn 1 0.13 0.38 0
77 INT44232 FSHR Regulation of PLOD1 1 0.15 0.9 0
78 INT44229 TRH Regulation of FSHR 1 0.11 0.9 0
79 INT187670 Gene_expression of FSHR Positive_regulation of Gene_expression of CYP19A1 1 0.16 0 0
80 INT44231 Negative_regulation of Binding of FSHR and TRH 1 0.39 0.91 0
81 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0
82 INT214885 Binding of PDGFRA and Atcay 1 0.08 4.05 0
83 INT295431 FSHR Positive_regulation of CGA 1 0.29 0.27 0
84 INT315187 Binding of SFRP1 and COPD 1 0.01 4.47 0
85 INT260072 Binding of BRCA2 and FANCC 1 0.37 0.63 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for female gonad development. They are ordered first by their pain relevance and then by number of times they were reported in female gonad development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1644 Regulation of FSHR 77 0.55 15.62 21.49
2 INT912 Localization of FSHR 91 0.79 23.61 15.58
3 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33
4 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04
5 INT65277 Negative_regulation of Fst 20 0.43 4.61 11.83
6 INT1647 Negative_regulation of FSHR 54 0.45 13.44 8.87
7 INT70572 Gene_expression of Fst 33 0.78 5.22 8.24
8 INT60931 Negative_regulation of Fst 15 0.57 5.44 7.21
9 INT86060 Positive_regulation of Fst 13 0.64 3.04 6.33
10 INT924 Regulation of Localization of FSHR 15 0.45 1.4 5.07
11 INT65276 Gene_expression of Fst 12 0.65 4.99 5.05
12 INT923 Positive_regulation of Localization of FSHR 14 0.43 2.48 4.96
13 INT1646 Negative_regulation of Localization of FSHR 17 0.58 7.36 3.46
14 INT33237 Regulation of Fst 10 0.39 1.3 3
15 INT163580 Positive_regulation of Fst 4 0.19 2.85 2.17
16 INT138316 Regulation of Fst 5 0.44 1.15 1.99
17 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
18 INT33496 Positive_regulation of Gene_expression of FSHR 14 0.46 6.05 1.66
19 INT280933 Binding of Fst 4 0.12 3.53 1.63
20 INT89467 Gene_expression of Lhcgr 9 0.36 1.59 1.62
21 INT7033 Binding of FSHR 19 0.37 6.66 1.52
22 INT1641 Positive_regulation of Negative_regulation of FSHR 3 0.41 1.7 1.43
23 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
24 INT25032 Negative_regulation of Gene_expression of FSHR 11 0.39 1.99 1.2
25 INT122347 Transcription of Hsd3b1 1 0.52 0 0.99
26 INT47039 Regulation of SFRP1 14 0.62 7.44 0.92
27 INT280942 Localization of Fst 2 0.22 2.13 0.91
28 INT35299 Regulation of Positive_regulation of FSHR 1 0.05 0 0.91
29 INT119102 Gene_expression of PDGFRA 13 0.75 11.99 0.81
30 INT147433 Gene_expression of BRCA2 7 0.62 7.02 0.79
31 INT25030 Negative_regulation of Negative_regulation of FSHR 2 0.25 0 0.79
32 INT34892 Transcription of FSHR 2 0.27 0.08 0.68
33 INT156967 Localization of Fst 2 0.66 0.1 0.66
34 INT156968 Negative_regulation of Localization of Fst 1 0.37 0.1 0.64
35 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63
36 INT349703 Positive_regulation of Transcription of Fst 1 0.46 0.14 0.53
37 INT349725 Transcription of Fst 1 0.63 0.13 0.53
38 INT34890 Regulation of Transcription of FSHR 1 0.17 0 0.52
39 INT135366 Localization of SFRP1 4 0.75 1.82 0.47
40 INT122348 Regulation of Hsd3b1 1 0.60 0 0.46
41 INT89465 Positive_regulation of Gene_expression of Lhcgr 4 0.24 1.03 0.41
42 INT117096 Gene_expression of Wnt4 2 0.67 4.68 0.38
43 INT317694 Negative_regulation of Localization of Fst 1 0.12 0.79 0.36
44 INT288541 Negative_regulation of Gene_expression of Fst 2 0.23 1.18 0.34
45 INT349714 Binding of Fst 1 0.34 0.19 0.32
46 INT156411 Gene_expression of Pdgfra 8 0.75 5.5 0.3
47 INT25047 Positive_regulation of Regulation of FSHR 3 0.31 0.92 0.29
48 INT173223 Negative_regulation of BRCA2 7 0.54 6.79 0.25
49 INT156410 Positive_regulation of Pdgfra 3 0.08 1.51 0.25
50 INT89466 Regulation of Gene_expression of Lhcgr 1 0.29 0 0.25
51 INT7977 Regulation of Gene_expression of FSHR 4 0.44 0.79 0.24
52 INT19359 Binding of BRCA2 5 0.47 2.63 0.19
53 INT159231 Positive_regulation of PDGFRA 3 0.47 2.39 0.18
54 INT89690 Binding of Brca2 2 0.37 1.8 0.18
55 INT7036 Negative_regulation of Regulation of FSHR 2 0.29 0.14 0.17
56 INT151741 Regulation of PDGFRA 2 0.44 0.78 0.16
57 INT222654 Regulation of Gene_expression of Fst 1 0.09 0 0.15
58 INT89691 Regulation of Brca2 1 0.23 0.56 0.13
59 INT106498 Positive_regulation of Lhcgr 2 0.08 0.41 0.12
60 INT210482 Regulation of Regulation of FSHR 1 0.03 0.07 0.12
61 INT200267 Transcription of Lhcgr 1 0.09 0 0.12
62 INT151342 Positive_regulation of Positive_regulation of FSHR 5 0.20 1.79 0.11
63 INT136182 Negative_regulation of PDGFRA 3 0.43 2.43 0.08
64 INT232713 Binding of PDGFRA 1 0.35 1.43 0.08
65 INT234186 Localization of BRCA2 2 0.69 1.48 0.07
66 INT206866 Positive_regulation of SFRP1 7 0.51 3.97 0.05
67 INT287913 Positive_regulation of Gene_expression of SFRP1 2 0.25 2.12 0.05
68 INT222593 Negative_regulation of Gene_expression of Fst 1 0.07 0 0.05
69 INT340535 Positive_regulation of Gene_expression of Fst 1 0.26 0.4 0.03
70 INT340540 Regulation of Gene_expression of Fst 1 0.17 0.42 0.03
71 INT226288 Negative_regulation of SFRP1 6 0.43 4.45 0
72 INT222613 Positive_regulation of Gene_expression of Fst 4 0.42 0.25 0
73 INT167536 Positive_regulation of BRCA2 2 0.49 0.29 0
74 INT234191 Positive_regulation of Localization of BRCA2 1 0.46 0.68 0
75 INT314708 Gene_expression of Brca2 1 0.41 1.75 0
76 INT223183 Positive_regulation of Lhcgr 1 0.09 0.2 0
77 INT318007 Regulation of Lhcgr 1 0.40 0.63 0
78 INT352608 Binding of Pdgfra 1 0.27 0.7 0
79 INT314707 Regulation of Transcription of Brca2 1 0.27 0.56 0
80 INT176565 Protein_catabolism of FSHR 1 0.26 0.13 0
81 INT132329 Regulation of Negative_regulation of FSHR 1 0.13 0.17 0
82 INT295427 Localization of PDGFRA 1 0.40 1.04 0
83 INT315189 Binding of SFRP1 1 0.15 2.96 0
84 INT226287 Regulation of Gene_expression of SFRP1 1 0.38 0.37 0
85 INT314705 Transcription of Brca2 1 0.42 0.56 0
86 INT352609 Positive_regulation of Gene_expression of Pdgfra 1 0.58 1.18 0
87 INT205585 Regulation of Wnt4 1 0.45 0.7 0
88 INT205578 Negative_regulation of Wnt4 1 0.43 1.69 0
89 INT173224 Regulation of BRCA2 1 0.21 1.3 0
90 INT200836 Transcription of Pdgfra 1 0.30 0.26 0
91 INT226286 Negative_regulation of Gene_expression of SFRP1 1 0.31 0.7 0
92 INT290240 Binding of ZFP42 1 0.31 0.28 0
93 INT205581 Regulation of Negative_regulation of Wnt4 1 0.27 0.7 0
94 INT294017 Negative_regulation of Localization of SFRP1 1 0.32 0.47 0
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