GO:0008593

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Name regulation of Notch signaling pathway
Categary Process
Go Slim No
Go Link GO:0008593
Unique Molecular Interactions 26
Total Molecular Interactions 47
Total Single Events 113
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of Notch signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for regulation of Notch signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
2 INT333966 Binding of Il6r and Il6st 1 0.01 1.74 1.1
3 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97
4 INT328821 Binding of Il6st and Jak1 1 0.05 0 0.38
5 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
6 INT328824 Binding of Il6st and TYK2 1 0.02 0 0.38
7 INT183444 POSTN Positive_regulation of CUX1 1 0.01 0 0.21
8 INT183443 C7 Positive_regulation of POSTN 1 0.00 0 0.19
9 INT327879 Binding of Itgb1 and Postn 1 0.02 1.05 0.14
10 INT254488 Dtx1 Regulation of Sorbs1 1 0.01 0 0.12
11 INT254490 Dtx1 Regulation of Gopc 1 0.04 0 0.12
12 INT254492 Dtx1 Regulation of Cldn11 1 0.03 0 0.09
13 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08
14 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08
15 INT327871 Binding of Notch1 and Postn 1 0.38 1.42 0.07
16 INT327875 Binding of Col7a1 and Postn 1 0.02 0.58 0.04
17 INT327876 Postn Regulation of Gene_expression of Notch1 1 0.56 0.92 0.03
18 INT327870 Postn Positive_regulation of Gene_expression of Notch1 1 0.37 0.57 0
19 INT327873 Postn Regulation of Notch1 1 0.41 0 0
20 INT311211 Binding of Plec and Postn 1 0.00 0.6 0
21 INT197309 Ascl1 Regulation of Neurod1 1 0.01 0.13 0
22 INT327878 Binding of Egf and Postn 1 0.18 0.37 0
23 INT327872 Binding of Postn and Pkn1 1 0.03 0.21 0
24 INT197314 Hes5 Regulation of Ascl1 1 0.00 0.14 0
25 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
26 INT197307 Ascl1 Regulation of Neurod6 1 0.00 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of Notch signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in regulation of Notch signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT152030 Gene_expression of Postn 10 0.55 8.09 7.08
2 INT89986 Gene_expression of Il6st 5 0.56 2.35 3.15
3 INT17061 Positive_regulation of POSTN 12 0.42 5.33 2.28
4 INT216670 Negative_regulation of Postn 3 0.35 1.54 1.9
5 INT244600 Negative_regulation of POSTN 5 0.18 3.12 1.64
6 INT244735 Gene_expression of Ascl1 12 0.58 2.48 1.54
7 INT253403 Positive_regulation of Il6st 2 0.28 2.07 1.54
8 INT85836 Positive_regulation of Postn 3 0.03 1.81 1.43
9 INT159009 Regulation of Il6st 2 0.18 2 1.41
10 INT228918 Negative_regulation of Gene_expression of Postn 1 0.03 0.44 1.32
11 INT314780 Regulation of Postn 1 0.13 1.53 1.17
12 INT333965 Binding of Il6st 1 0.08 0.9 0.65
13 INT321199 Binding of POSTN 2 0.31 1.94 0.62
14 INT345502 Positive_regulation of Binding of POSTN 1 0.07 0.93 0.62
15 INT183447 Localization of POSTN 1 0.03 0 0.35
16 INT126195 Transcription of Il6st 1 0.39 0.2 0.28
17 INT281972 Gene_expression of POSTN 3 0.65 14.9 0.22
18 INT310471 Regulation of Ascl1 1 0.34 0.19 0.22
19 INT310462 Positive_regulation of Gene_expression of Ascl1 1 0.37 0.52 0.17
20 INT319397 Positive_regulation of Gene_expression of POSTN 2 0.48 4.56 0.16
21 INT254481 Regulation of Dtx1 1 0.04 0 0.16
22 INT310488 Binding of Ascl1 1 0.28 0.25 0.16
23 INT327863 Binding of Postn 1 0.30 1.27 0.14
24 INT299517 Positive_regulation of Gene_expression of Il6st 1 0.06 0.23 0.09
25 INT310484 Positive_regulation of Ascl1 1 0.37 0.47 0.09
26 INT243508 Negative_regulation of Dtx1 1 0.01 0.55 0.06
27 INT253389 Positive_regulation of Positive_regulation of Il6st 1 0.28 0.07 0.05
28 INT321200 Regulation of Gene_expression of POSTN 1 0.38 0.12 0
29 INT84404 Localization of Postn 1 0.00 0 0
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