GO:0008631

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Name induction of apoptosis by oxidative stress
Categary Process
Go Slim No
Go Link GO:0008631
Unique Molecular Interactions 203
Total Molecular Interactions 241
Total Single Events 3558
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for induction of apoptosis by oxidative stress. They are ordered first by their pain relevance and then by number of times they were reported for induction of apoptosis by oxidative stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
2 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
3 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
4 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
5 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
6 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
7 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
8 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
9 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
10 INT158144 Binding of Gpx1 and Glyat 2 0.31 0 1.29
11 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
12 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
13 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
14 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
15 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
16 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
17 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
18 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
19 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
20 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
21 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
22 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
23 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
24 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
25 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
26 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
27 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
28 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
29 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
30 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
31 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
32 INT307045 Tmie Negative_regulation of Positive_regulation of Casp3 1 0.01 0.29 0.85
33 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
34 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
35 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81
36 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8
37 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
38 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
39 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
40 INT307044 Tmie Regulation of Casp3 1 0.01 0 0.75
41 INT114860 Negative_regulation of Insrr Positive_regulation of Casp3 1 0.02 0.71 0.73
42 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
43 INT151559 Atp2a1 Negative_regulation of Positive_regulation of CASP3 1 0.06 0.68 0.66
44 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
45 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
46 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
47 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
48 INT11558 POMC Positive_regulation of CASP3 1 0.05 0 0.62
49 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
50 INT114505 Negative_regulation of Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
51 INT114506 Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
52 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
53 INT163376 RYBP Positive_regulation of Gene_expression of Casp3 2 0.01 0.57 0.59
54 INT112399 Olr897-ps Regulation of Gene_expression of Casp3 1 0.03 0 0.54
55 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
56 INT74517 Binding of Casp3 and Cnrip1 1 0.31 0 0.51
57 INT234609 Binding of CASP3 and IMMT 1 0.00 0.5 0.5
58 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
59 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
60 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
61 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
62 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
63 INT307048 Cnr1 Positive_regulation of Casp3 1 0.08 0 0.47
64 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
65 INT161654 Gsr Regulation of Gpx1 1 0.14 0.85 0.42
66 INT168435 Positive_regulation of Binding of GLRX and Gpx1 1 0.05 0.91 0.42
67 INT168434 Binding of GLRX and Gpx1 1 0.04 0.9 0.42
68 INT57236 Casp3 Positive_regulation of Prl 1 0.09 0 0.41
69 INT57235 Casp3 Positive_regulation of Localization of Prl 1 0.15 0 0.4
70 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
71 INT168461 Sult1a1 Positive_regulation of Gpx1 1 0.12 0.83 0.39
72 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
73 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
74 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
75 INT52960 Casp3 Negative_regulation of Positive_regulation of Ltp 1 0.02 0 0.37
76 INT145908 Pdyn Regulation of Positive_regulation of Casp3 1 0.14 0.94 0.37
77 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
78 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
79 INT286708 Negative_regulation of Mapk1 Negative_regulation of Casp3 1 0.12 0 0.31
80 INT166162 Ccr9 Negative_regulation of Positive_regulation of Casp3 1 0.18 1.49 0.28
81 INT148629 Binding of Cat and Casp3 1 0.08 0.09 0.26
82 INT121249 Binding of ANXA5 and CASP3 1 0.36 0.67 0.25
83 INT149713 Binding of Casp3 and Fas 1 0.40 1.09 0.25
84 INT171049 Binding of FAS and Positive_regulation of Gene_expression of CASP3 1 0.04 1.41 0.24
85 INT292554 MAP3K5 Positive_regulation of MAPK8 1 0.08 0 0.23
86 INT292561 MAP3K5 Positive_regulation of Positive_regulation of RAC1 1 0.03 0 0.23
87 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
88 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22
89 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22
90 INT349344 Bdnf Negative_regulation of Casp3 1 0.13 0.96 0.22
91 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22
92 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21
93 INT181675 Positive_regulation of Casp9 Positive_regulation of Casp3 1 0.06 0.51 0.2
94 INT315384 Adcyap1 Negative_regulation of Positive_regulation of Casp3 1 0.02 0.53 0.2
95 INT181677 Casp9 Positive_regulation of Casp3 1 0.06 0.5 0.19
96 INT261387 Nsdhl Negative_regulation of Casp3 1 0.03 1.08 0.19
97 INT51343 Binding of Pomc and Diablo 1 0.25 0 0.19
98 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
99 INT351442 Gria2 Regulation of Gene_expression of Casp3 1 0.01 0 0.18
100 INT275400 Casp3 Positive_regulation of NDRG1 1 0.00 1.36 0.18
101 INT148103 MAPK8 Positive_regulation of STK24 1 0.47 1.82 0.17
102 INT96416 CYC1 Positive_regulation of Casp3 1 0.02 0.96 0.17
103 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
104 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15
105 INT226205 Negative_regulation of Akt1 Positive_regulation of Casp3 1 0.04 0.71 0.14
106 INT252573 Rpe Negative_regulation of Gpx1 1 0.07 2.34 0.13
107 INT275397 Binding of ITIH4 and Casp3 1 0.02 0.64 0.13
108 INT252631 Binding of Casp3 and Tnfrsf1a 1 0.10 0.69 0.13
109 INT275389 Binding of Casp3 and Htatsf1 1 0.00 0.64 0.13
110 INT143661 Abl1 Regulation of Gpx1 1 0.19 0.56 0.12
111 INT321404 Positive_regulation of MAP3K5 Positive_regulation of Gene_expression of SERPINE1 1 0.02 2.2 0.12
112 INT252632 Binding of Casp3 and Tradd 1 0.11 0.68 0.12
113 INT349345 Bdnf Negative_regulation of Positive_regulation of Casp3 1 0.13 1.02 0.12
114 INT201754 CASP8 Positive_regulation of Casp3 1 0.00 0.47 0.12
115 INT315391 IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
116 INT143662 Rere Regulation of Gpx1 1 0.69 0.56 0.12
117 INT315390 Positive_regulation of IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
118 INT142961 Binding of Nfkb1 and Casp3 1 0.00 1.02 0.11
119 INT234062 Nes Positive_regulation of Casp3 1 0.18 0.08 0.11
120 INT188358 Binding of Csf2 and Positive_regulation of Jak2 1 0.34 0.19 0.11
121 INT169340 Binding of UGT8 and Jak2 1 0.36 0.15 0.11
122 INT51346 Binding of Vtn and Diablo 1 0.02 0 0.1
123 INT148102 AGT Positive_regulation of Gene_expression of STK24 1 0.37 0.96 0.1
124 INT285023 Casp3 Negative_regulation of Casp7 1 0.07 0.44 0.1
125 INT242480 Ciapin1 Positive_regulation of Gene_expression of Jak2 1 0.27 1.05 0.07
126 INT203849 Ass1 Positive_regulation of Casp3 1 0.00 0.71 0.07
127 INT200807 Jak2 Positive_regulation of Mvd 1 0.18 3.46 0.06
128 INT175966 Kctd1 Negative_regulation of Positive_regulation of CASP3 1 0.09 0.82 0.06
129 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
130 INT302129 BAX Regulation of Positive_regulation of CASP3 1 0.02 0.69 0.06
131 INT344254 Binding of PARP1 and CASP3 1 0.06 0.94 0.06
132 INT211347 Binding of Sigmar1 and Positive_regulation of Casp3 1 0.12 0.92 0.06
133 INT208432 Sms Negative_regulation of Negative_regulation of Gpx1 1 0.14 0.61 0.05
134 INT208433 Sms Positive_regulation of Gene_expression of Gpx1 1 0.25 0.53 0.05
135 INT302162 CASP8 Positive_regulation of CASP3 2 0.01 2.07 0.04
136 INT242411 Mch Positive_regulation of Casp3 1 0.09 0.15 0.04
137 INT234379 BAX Positive_regulation of CASP3 1 0.04 1.16 0.04
138 INT302983 Fadd Positive_regulation of Casp3 1 0.15 1.13 0.04
139 INT347414 Tlr4 Negative_regulation of Gpx1 1 0.01 0.36 0.04
140 INT242413 Regulation of Mch Positive_regulation of Casp3 1 0.05 0.16 0.04
141 INT267217 Gene_expression of Hspb8 Negative_regulation of Positive_regulation of Casp3 1 0.14 2.8 0.04
142 INT322358 Binding of Parp1 and Casp3 1 0.05 1.08 0.04
143 INT200821 Binding of Jak2 and Mvd 1 0.14 0.68 0.04
144 INT252767 CAT Regulation of Gpx1 1 0.00 0.25 0.04
145 INT193778 ITIH4 Positive_regulation of CASP3 1 0.03 0.98 0.03
146 INT200813 Jak2 Positive_regulation of Akt1 1 0.26 1.46 0.03
147 INT253578 Csnk2a2 Negative_regulation of Jak2 1 0.09 0 0.03
148 INT253573 Binding of Jak2 and Pik3r1 1 0.06 0 0.03
149 INT200816 Jak2 Positive_regulation of Binding of Mvd 1 0.19 1.51 0.03
150 INT223826 GSTM1 Negative_regulation of MAP3K5 1 0.02 0.71 0.03
151 INT223824 Binding of GSTM1 and MAP3K5 1 0.02 0.68 0.03
152 INT175946 RSF1 Positive_regulation of Positive_regulation of CASP3 1 0.01 0.41 0.03
153 INT172897 Negative_regulation of Lox Positive_regulation of Positive_regulation of Casp3 1 0.04 1.19 0.03
154 INT200810 Jak2 Positive_regulation of Src 1 0.29 1.46 0.03
155 INT172910 Lox Positive_regulation of Positive_regulation of Casp3 1 0.03 1.19 0.03
156 INT249597 Jak2 Positive_regulation of Phosphorylation of Stat1 1 0.20 0.13 0.03
157 INT253575 Binding of Jak2 and Pik3r2 1 0.00 0 0.03
158 INT200815 Binding of Epo and Jak2 1 0.36 0.98 0.03
159 INT345350 Casp3 Positive_regulation of Prkcd 1 0.05 0.79 0.03
160 INT200822 Akt1 Regulation of Jak2 1 0.25 1.48 0.03
161 INT327981 CASP9 Positive_regulation of CASP3 2 0.29 1.34 0
162 INT286268 Binding of GSR and Gpx1 2 0.02 0 0
163 INT277693 Stat6 Positive_regulation of Positive_regulation of Casp3 1 0.01 1.01 0
164 INT333772 Positive_regulation of Casp3 Positive_regulation of Gga3 1 0.05 0.5 0
165 INT348532 TP63 Positive_regulation of CASP3 1 0.04 0.55 0
166 INT247847 Narfl Positive_regulation of Positive_regulation of Casp3 1 0.02 0.79 0
167 INT279798 APAF1 Positive_regulation of CASP3 1 0.01 1 0
168 INT333696 Tpsg1 Positive_regulation of Casp3 1 0.08 3.18 0
169 INT340502 Agtr1a Negative_regulation of Phosphorylation of Jak2 1 0.12 2.32 0
170 INT157755 Tmx1 Regulation of Positive_regulation of Casp3 1 0.15 0 0
171 INT253366 Il6 Positive_regulation of Phosphorylation of Jak2 1 0.31 0.2 0
172 INT277691 Cdkn1a Negative_regulation of Positive_regulation of Casp3 1 0.00 1.01 0
173 INT349220 Binding of CASP3 and CD8A 1 0.00 0.18 0
174 INT186096 EGF Regulation of Positive_regulation of CASP3 1 0.01 0.28 0
175 INT333771 Casp3 Positive_regulation of Gga3 1 0.05 0.5 0
176 INT200819 Epo Positive_regulation of Gene_expression of Jak2 1 0.49 0.91 0
177 INT155123 Binding of Gpx1 and Cat 1 0.04 0.05 0
178 INT327982 PNLIP Regulation of Gene_expression of CASP3 1 0.13 0.58 0
179 INT167401 Ros1 Positive_regulation of CASP3 1 0.15 0.71 0
180 INT226042 Binding of Casp1 and Casp3 1 0.02 0.73 0
181 INT155124 Positive_regulation of Binding of Gpx1 and Cat 1 0.05 0.05 0
182 INT175400 RASGRP1 Positive_regulation of MAP3K5 1 0.00 1.2 0
183 INT268633 Mpz Positive_regulation of Positive_regulation of Casp3 1 0.14 0 0
184 INT157754 Tmx1 Regulation of Gene_expression of Casp3 1 0.15 0 0
185 INT336036 Positive_regulation of CASP9 Positive_regulation of CASP3 1 0.05 0.75 0
186 INT229809 Fos Regulation of Casp3 1 0.06 0.32 0
187 INT265460 CSPG4 Negative_regulation of Positive_regulation of CASP3 1 0.06 0.27 0
188 INT322365 TNF Positive_regulation of Positive_regulation of Casp3 1 0.01 1.54 0
189 INT247888 Narfl Positive_regulation of CASP3 1 0.00 0.77 0
190 INT333698 Gene_expression of Hr Negative_regulation of Casp3 1 0.14 0.73 0
191 INT351596 Regulation of Binding of GSR and Gpx1 1 0.02 0 0
192 INT201755 ROS1 Positive_regulation of Casp3 1 0.00 1.4 0
193 INT241535 Abl1 Regulation of Positive_regulation of Jak2 1 0.10 0.53 0
194 INT263335 Olfm4 Regulation of Regulation of Casp3 1 0.00 0.33 0
195 INT319170 Casp3 Regulation of Hdac1 1 0.01 0.27 0
196 INT327979 Positive_regulation of CASP9 Positive_regulation of Gene_expression of CASP3 1 0.07 0.78 0
197 INT348535 CASP10 Positive_regulation of CASP3 1 0.03 0.3 0
198 INT277694 Cdkn1a Positive_regulation of Positive_regulation of Casp3 1 0.00 1.01 0
199 INT242159 Wnt2 Positive_regulation of Localization of Casp3 1 0.05 0.25 0
200 INT206963 Lipg Regulation of Gpx1 1 0.00 0.5 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for induction of apoptosis by oxidative stress. They are ordered first by their pain relevance and then by number of times they were reported in induction of apoptosis by oxidative stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
2 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
3 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
4 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
5 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
6 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
7 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
8 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38
9 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
10 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
11 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
12 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
13 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
14 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
15 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07
16 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
17 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2
18 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
19 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
20 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77
21 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
22 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
23 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
24 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83
25 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
26 INT98178 Localization of Casp3 32 0.65 21.01 7.77
27 INT102814 Negative_regulation of CASP3 46 0.43 28.54 6.94
28 INT102749 Positive_regulation of Positive_regulation of CASP3 32 0.67 26.07 6.93
29 INT108585 Positive_regulation of Gene_expression of CASP3 35 0.70 28.37 6.45
30 INT57232 Binding of Casp3 22 0.36 9.42 6.2
31 INT134544 Negative_regulation of Positive_regulation of CASP3 23 0.57 18.48 5.95
32 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
33 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
34 INT88805 Protein_catabolism of CASP3 24 0.86 18.38 3.7
35 INT97126 Regulation of CASP3 9 0.40 8.15 3.6
36 INT53584 Regulation of Gpx1 19 0.62 14.38 3.48
37 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
38 INT90289 Positive_regulation of Gene_expression of Gpx1 10 0.17 8.07 3.05
39 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74
40 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
41 INT131112 Phosphorylation of Casp3 7 0.63 4.1 2.46
42 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
43 INT31118 Localization of Casp3 17 0.73 11.55 2.3
44 INT108589 Negative_regulation of Gene_expression of CASP3 13 0.57 10.52 2.14
45 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12
46 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
47 INT94848 Negative_regulation of Gene_expression of Gpx1 11 0.30 4.91 1.7
48 INT148804 Binding of Diablo 3 0.47 4.37 1.67
49 INT102532 Protein_catabolism of Casp3 24 0.64 16.78 1.64
50 INT67869 Transcription of Gpx1 3 0.68 0.67 1.56
51 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
52 INT106749 Negative_regulation of Negative_regulation of Casp3 6 0.34 5.12 1.48
53 INT140843 Regulation of Phosphorylation of Casp3 1 0.25 0.37 1.44
54 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
55 INT171690 Transcription of Casp3 8 0.55 2.62 1.36
56 INT97943 Positive_regulation of Protein_catabolism of Casp3 7 0.28 7.4 1.35
57 INT102845 Localization of CASP3 7 0.81 2.81 1.06
58 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04
59 INT89887 Regulation of Gene_expression of Gpx1 3 0.32 0.8 1.02
60 INT31117 Binding of Casp3 14 0.23 5.27 0.93
61 INT169336 Binding of Jak2 2 0.42 1.31 0.93
62 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
63 INT116141 Localization of Diablo 2 0.78 2.04 0.89
64 INT184027 Phosphorylation of Jak2 6 0.82 2.58 0.87
65 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
66 INT131105 Positive_regulation of Negative_regulation of Casp3 3 0.29 3.15 0.84
67 INT237408 Positive_regulation of Positive_regulation of Jak2 1 0.28 1.56 0.79
68 INT181667 Regulation of Regulation of Casp3 1 0.22 1.7 0.77
69 INT168432 Negative_regulation of Positive_regulation of Gpx1 4 0.40 2.89 0.75
70 INT129490 Negative_regulation of Protein_catabolism of Casp3 4 0.22 3.91 0.71
71 INT351454 Regulation of Transcription of Casp3 1 0.02 0.51 0.67
72 INT131976 Positive_regulation of Protein_catabolism of CASP3 4 0.49 3.76 0.64
73 INT148230 Positive_regulation of Regulation of Gpx1 1 0.31 0.58 0.6
74 INT242061 Positive_regulation of Negative_regulation of Casp3 3 0.09 1.7 0.58
75 INT181673 Negative_regulation of Transcription of Casp3 3 0.34 0.61 0.55
76 INT184062 Binding of Jak2 5 0.37 3.13 0.47
77 INT129144 Regulation of Localization of Casp3 1 0.26 0.84 0.44
78 INT153436 Positive_regulation of Localization of Casp3 3 0.49 2.12 0.43
79 INT205890 Transcription of Jak2 1 0.41 0.22 0.43
80 INT132496 Regulation of Gene_expression of CASP3 6 0.20 4.59 0.42
81 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41
82 INT155293 Positive_regulation of Protein_catabolism of Casp3 3 0.45 1.7 0.4
83 INT107462 Localization of Jak2 2 0.60 0.78 0.4
84 INT229697 Negative_regulation of Phosphorylation of Jak2 1 0.15 0.54 0.39
85 INT321424 Positive_regulation of MAP3K5 1 0.18 6.64 0.37
86 INT200786 Positive_regulation of Gene_expression of Jak2 9 0.69 6.03 0.35
87 INT205910 Negative_regulation of Positive_regulation of Jak2 1 0.33 0.26 0.35
88 INT165916 Negative_regulation of Localization of Casp3 2 0.41 2.41 0.34
89 INT137586 Binding of Gpx1 8 0.23 2.76 0.29
90 INT116703 Negative_regulation of Negative_regulation of Gpx1 3 0.18 0.81 0.28
91 INT148104 Gene_expression of STK24 1 0.77 2.85 0.28
92 INT148105 Positive_regulation of Gene_expression of STK24 1 0.69 2.86 0.28
93 INT159320 Negative_regulation of Protein_catabolism of CASP3 1 0.21 0.59 0.27
94 INT321428 Positive_regulation of Positive_regulation of MAP3K5 1 0.13 4.65 0.25
95 INT141820 Positive_regulation of Binding of Casp3 1 0.12 0.55 0.24
96 INT195018 Regulation of Negative_regulation of Casp3 1 0.21 0.48 0.2
97 INT274775 Regulation of Positive_regulation of Gpx1 1 0.04 0.76 0.2
98 INT328811 Negative_regulation of Localization of Jak2 1 0.34 0.13 0.17
99 INT200802 Regulation of Jak2 5 0.61 2.86 0.16
100 INT178607 Binding of CASP3 5 0.19 1.06 0.16
101 INT177568 Localization of Gpx1 5 0.49 1.82 0.16
102 INT123522 Phosphorylation of Casp3 3 0.80 1.36 0.14
103 INT143657 Phosphorylation of Gpx1 1 0.82 0.97 0.14
104 INT143658 Regulation of Phosphorylation of Gpx1 1 0.45 0.97 0.14
105 INT143659 Positive_regulation of Phosphorylation of Gpx1 1 0.50 0.98 0.14
106 INT314341 Positive_regulation of Localization of Gpx1 1 0.08 0.82 0.13
107 INT226041 Positive_regulation of Binding of Casp3 1 0.12 0.82 0.12
108 INT278143 Positive_regulation of Negative_regulation of Jak2 1 0.16 0.54 0.11
109 INT190821 Positive_regulation of Negative_regulation of CASP3 1 0.06 0.51 0.1
110 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09
111 INT252568 Negative_regulation of Regulation of Gpx1 1 0.08 1.11 0.09
112 INT51338 Binding of Diablo 1 0.24 0 0.09
113 INT171688 Positive_regulation of Transcription of Casp3 3 0.28 1.16 0.08
114 INT184018 Negative_regulation of Protein_catabolism of Jak2 1 0.36 1.76 0.08
115 INT184023 Protein_catabolism of Jak2 1 0.61 1.75 0.08
116 INT288609 Regulation of Regulation of Casp3 1 0.05 0.69 0.07
117 INT333205 Negative_regulation of Protein_catabolism of Casp3 1 0.04 0.6 0.05
118 INT265483 Phosphorylation of CASP3 1 0.22 0.25 0.04
119 INT215417 Gene_expression of MAP3K5 4 0.23 0.59 0
120 INT213908 Negative_regulation of MAP3K5 2 0.41 0.87 0
121 INT243797 Transcription of CASP3 2 0.09 0.82 0
122 INT348502 Regulation of Negative_regulation of CASP3 1 0.09 0.38 0
123 INT304140 Regulation of Negative_regulation of Casp3 1 0.05 0.67 0
124 INT239147 Regulation of Binding of Gpx1 1 0.28 0.53 0
125 INT237443 Positive_regulation of Phosphorylation of Casp3 1 0.39 0.09 0
126 INT159172 Negative_regulation of Negative_regulation of Casp3 1 0.09 0.07 0
127 INT268724 Positive_regulation of Negative_regulation of Gpx1 1 0.04 0.13 0
128 INT202420 Transcription of Jak2 1 0.56 0.91 0
129 INT166505 Positive_regulation of Diablo 1 0.30 0.06 0
130 INT338700 Positive_regulation of Diablo 1 0.45 1.18 0
131 INT252739 Localization of MAP3K5 1 0.19 0.74 0
132 INT166506 Positive_regulation of Localization of Diablo 1 0.67 0.06 0
133 INT166504 Localization of Diablo 1 0.78 0.06 0
134 INT335757 Positive_regulation of Positive_regulation of Gpx1 1 0.07 0.66 0
135 INT228785 Positive_regulation of Transcription of Casp3 1 0.17 0.06 0
136 INT347402 Negative_regulation of Binding of Gpx1 1 0.05 0 0
137 INT242155 Negative_regulation of Localization of Casp3 1 0.04 0.25 0
138 INT228792 Transcription of Casp3 1 0.24 0.05 0
139 INT208466 Positive_regulation of Localization of CASP3 1 0.01 0.98 0
140 INT166507 Negative_regulation of Localization of Diablo 1 0.42 0.06 0
141 INT351593 Positive_regulation of Binding of Gpx1 1 0.08 0 0
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