GO:0008656

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Name cysteine-type endopeptidase activator activity involved in apoptotic process
Categary Function
Go Slim No
Go Link GO:0008656
Unique Molecular Interactions 220
Total Molecular Interactions 287
Total Single Events 1585
Pain Genes Associated 20

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cysteine-type endopeptidase activator activity involved in apoptotic process. They are ordered first by their pain relevance and then by number of times they were reported for cysteine-type endopeptidase activator activity involved in apoptotic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT164362 Binding of NLRP1 and VTA1 1 0.15 2.37 4.67
2 INT164365 Positive_regulation of Binding of NLRP1 and VTA1 1 0.14 0.6 1.21
3 INT76199 CASP1 Positive_regulation of CEL 1 0.06 0.32 1.14
4 INT289173 PYCARD Regulation of MFGE8 1 0.05 0 0.96
5 INT164363 Regulation of Binding of NLRP1 and VTA1 1 0.14 0.45 0.86
6 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85
7 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85
8 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
9 INT142057 NLRP1 Regulation of Gene_expression of Fos 1 0.17 0 0.76
10 INT91655 SLC8A1 Negative_regulation of CASP1 1 0.02 0.43 0.75
11 INT216668 Positive_regulation of NLRP1 Regulation of Vta1 1 0.00 0 0.73
12 INT278812 PYCARD Positive_regulation of VTA1 1 0.09 0.11 0.71
13 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
14 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
15 INT179203 NLRP1 Regulation of Gene_expression of TNF 1 0.31 1.73 0.6
16 INT76200 CASP1 Positive_regulation of Gene_expression of PTGS1 1 0.05 0.16 0.54
17 INT126341 Tac1 Regulation of Gene_expression of Tnfrsf10b 1 0.06 0.71 0.52
18 INT5856 Bad Positive_regulation of Gene_expression of Penk 1 0.02 0.37 0.5
19 INT115184 Regulation of CASP1 Positive_regulation of MAPK9 1 0.09 0 0.49
20 INT150391 Binding of MEFV and PYCARD 4 0.14 3 0.48
21 INT115183 CASP1 Positive_regulation of Positive_regulation of MAPK9 1 0.16 0 0.48
22 INT115185 CASP1 Positive_regulation of MAPK9 1 0.15 0 0.48
23 INT338086 PYCARD Positive_regulation of TCEA1 1 0.10 0 0.47
24 INT338083 Binding of LEFTY1 and PYCARD 1 0.02 0 0.46
25 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45
26 INT155086 CASP1 Negative_regulation of DAXX 1 0.21 1.26 0.45
27 INT155085 CASP1 Negative_regulation of CASP8 1 0.29 1.25 0.44
28 INT112800 CASP1 Positive_regulation of Gene_expression of CCL2 1 0.04 0.48 0.43
29 INT228323 PYCARD Positive_regulation of FIG4 1 0.17 0 0.42
30 INT338085 Binding of PYCARD and GOPC 1 0.05 0 0.39
31 INT91656 SLC8A1 Negative_regulation of Positive_regulation of CASP1 1 0.01 0.2 0.38
32 INT278813 Binding of NOVA2 and PYCARD 1 0.13 0 0.38
33 INT91652 Negative_regulation of SLC8A1 Negative_regulation of CASP1 1 0.02 0.21 0.37
34 INT324813 Tlr4 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
35 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
36 INT324827 Hmgb1 Positive_regulation of Bad 1 0.02 0.43 0.36
37 INT179201 NLRP1 Regulation of Gene_expression of IL10 1 0.06 0.77 0.36
38 INT324808 Tlr4 Positive_regulation of Bad 1 0.02 0.43 0.36
39 INT112619 Mapk9 Regulation of Il1b 1 0.16 1.11 0.36
40 INT112620 Mapk9 Regulation of Tnf 1 0.16 1.11 0.36
41 INT179202 NLRP1 Regulation of Gene_expression of IL6 1 0.07 0.77 0.36
42 INT315385 Adcyap1 Positive_regulation of Phosphorylation of Bad 1 0.05 0.44 0.32
43 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32
44 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32
45 INT289178 Regulation of PYCARD Regulation of MFGE8 1 0.05 0 0.32
46 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
47 INT166391 IFI27 Regulation of Gene_expression of CDKN1B 1 0.33 0.41 0.31
48 INT289175 PYCARD Regulation of behavior 1 0.03 0 0.31
49 INT166397 CDKN1B Regulation of Gene_expression of IFI27 1 0.33 0.41 0.31
50 INT334879 CASP1 Regulation of IL1B 1 0.03 1.63 0.31
51 INT242399 Cyp19a1 Negative_regulation of Gene_expression of Bad 1 0.00 1.32 0.31
52 INT29984 Bad Positive_regulation of Localization of Prl 1 0.15 0 0.3
53 INT112797 Positive_regulation of CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.3
54 INT219151 IL18 Positive_regulation of CASP1 1 0.01 1.05 0.3
55 INT289179 PYCARD Regulation of TW 1 0.02 0 0.3
56 INT112795 Positive_regulation of CASP1 Positive_regulation of MAPK8 1 0.02 0.16 0.3
57 INT112799 Positive_regulation of CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.3
58 INT112803 CASP1 Positive_regulation of MAPK8 1 0.02 0.16 0.29
59 INT112805 CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.29
60 INT116595 CASP1 Positive_regulation of IL6 1 0.07 0.46 0.28
61 INT116591 CASP1 Positive_regulation of PTGER2 1 0.01 0.46 0.28
62 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
63 INT172901 Binding of Bad and Bcl2l1 3 0.13 6.51 0.27
64 INT322021 Negative_regulation of CASP1 Positive_regulation of IL1B 1 0.04 0.13 0.26
65 INT292554 MAP3K5 Positive_regulation of MAPK8 1 0.08 0 0.23
66 INT292561 MAP3K5 Positive_regulation of Positive_regulation of RAC1 1 0.03 0 0.23
67 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
68 INT112794 CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.23
69 INT120376 Bad Positive_regulation of Gene_expression of Oxtr 1 0.08 0 0.22
70 INT274584 Binding of PSTPIP1 and PYCARD 1 0.13 1.34 0.22
71 INT289174 PYCARD Positive_regulation of MFGE8 1 0.05 0 0.21
72 INT112798 CASP1 Positive_regulation of CCL2 1 0.02 0.19 0.21
73 INT258456 PYCARD Negative_regulation of Localization of Tms 1 0.02 0.05 0.21
74 INT258455 Tms Negative_regulation of Localization of PYCARD 1 0.02 0.05 0.21
75 INT349668 Binding of HRH1 and PYCARD 1 0.00 0.37 0.21
76 INT91654 Negative_regulation of CASP1 Negative_regulation of IL1B 1 0.46 0.15 0.2
77 INT91653 Negative_regulation of CASP1 Negative_regulation of IL18 1 0.39 0.15 0.2
78 INT315386 Adcyap1 Positive_regulation of Bad 1 0.03 0.52 0.2
79 INT159794 Tnf Positive_regulation of Mapk9 1 0.01 0.42 0.19
80 INT159793 Tnf Positive_regulation of Gene_expression of Mapk9 1 0.01 0.42 0.19
81 INT339336 Binding of NKX3-1 and TAC4 1 0.03 0.08 0.18
82 INT289176 PYCARD Regulation of Localization of MFGE8 1 0.05 0 0.18
83 INT289177 PYCARD Regulation of Gene_expression of TW 1 0.03 0 0.18
84 INT349659 PYCARD Positive_regulation of ADRB2 1 0.06 0.19 0.17
85 INT137647 PYCARD Positive_regulation of NLN 1 0.02 0.08 0.15
86 INT137646 Negative_regulation of PYCARD Positive_regulation of NLN 1 0.02 0.08 0.15
87 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14
88 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
89 INT97517 Binding of PYCARD and Mefv 1 0.07 0.78 0.14
90 INT345146 Binding of Trip6 and Siva1 1 0.02 1.6 0.14
91 INT263321 Akt1 Regulation of Bad 1 0.00 0.74 0.13
92 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
93 INT147357 Mapk9 Positive_regulation of Htr5a 1 0.06 0.76 0.12
94 INT321404 Positive_regulation of MAP3K5 Positive_regulation of Gene_expression of SERPINE1 1 0.02 2.2 0.12
95 INT147362 Mapk9 Positive_regulation of Ddit3 1 0.57 0.76 0.12
96 INT182273 EDN1 Regulation of Gene_expression of BAD 1 0.11 0.73 0.12
97 INT147361 Mapk9 Positive_regulation of Tnfrsf10b 1 0.40 0.76 0.12
98 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
99 INT219152 NLRP3 Positive_regulation of Positive_regulation of CASP1 1 0.02 0.83 0.1
100 INT265889 BAX Regulation of Gene_expression of BAD 1 0.06 1.08 0.1
101 INT277692 Binding of Atp9a and Tnfrsf10b 1 0.00 1.47 0.1
102 INT233858 CHKA Positive_regulation of Gene_expression of CDKN1B 1 0.10 0.17 0.09
103 INT275184 Bad Positive_regulation of Positive_regulation of Bcl2l1 1 0.12 0.62 0.09
104 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
105 INT349660 Binding of INSR and PYCARD 1 0.01 0 0.09
106 INT270833 Binding of CASP1 and Panx1 1 0.02 0.14 0.09
107 INT270830 Panx1 Negative_regulation of CASP1 1 0.03 0.09 0.09
108 INT303124 Binding of Fas and Tnfrsf10b 1 0.09 1.03 0.08
109 INT270832 Negative_regulation of Panx1 Negative_regulation of Gene_expression of CASP1 1 0.03 0.14 0.08
110 INT322020 IL1B Regulation of Negative_regulation of CASP1 1 0.03 0 0.08
111 INT244130 Binding of CASP1 and RNGTT 1 0.07 0.24 0.07
112 INT244131 Binding of RNGTT and NLRP1 1 0.11 0.24 0.07
113 INT150388 Binding of MEFV and SIVA1 1 0.31 0.92 0.07
114 INT345173 Binding of Siva1 and Lpar2 1 0.05 0.75 0.06
115 INT265893 BAD Regulation of FOXO1 1 0.03 1.08 0.06
116 INT302150 MRPL28 Regulation of CDKN1B 1 0.09 0.26 0.06
117 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
118 INT302136 LAMTOR1 Regulation of CDKN1B 1 0.08 0.26 0.06
119 INT257879 Negative_regulation of Eif4e Positive_regulation of Cdkn1b 1 0.28 0.54 0.06
120 INT204079 HP Positive_regulation of Gene_expression of Cdkn1b 1 0.00 0.6 0.05
121 INT302133 IFI27 Regulation of CDKN1B 1 0.11 0.26 0.05
122 INT302130 CDKN1A Regulation of CDKN1B 1 0.04 0.26 0.05
123 INT302141 CDKN1C Regulation of CDKN1B 1 0.09 0.26 0.05
124 INT348523 BCL2L1 Negative_regulation of NLRP1 1 0.01 0.63 0.05
125 INT279902 Binding of GCLM and CARD8 1 0.28 0.82 0.05
126 INT349663 Binding of TFPI and PYCARD 1 0.04 0 0.04
127 INT331153 Akt1 Positive_regulation of Bad 1 0.03 0.92 0.04
128 INT331155 Akt1 Positive_regulation of Binding of Bad 1 0.04 0.93 0.04
129 INT290312 Binding of CASP1 and NCK1 1 0.00 0.29 0.04
130 INT331156 Akt1 Positive_regulation of Phosphorylation of Bad 1 0.02 0.91 0.04
131 INT244129 Binding of RNGTT and NOD1 1 0.11 0 0.04
132 INT266661 AKT1 Regulation of BAD 2 0.10 1.86 0.03
133 INT223826 GSTM1 Negative_regulation of MAP3K5 1 0.02 0.71 0.03
134 INT223824 Binding of GSTM1 and MAP3K5 1 0.02 0.68 0.03
135 INT345281 Binding of CASP1 and Nlrp3 1 0.02 0.31 0.03
136 INT244132 DDB1 Regulation of Transcription of NOD1 1 0.01 0.09 0.03
137 INT349661 PYCARD Positive_regulation of AR 1 0.08 0 0.03
138 INT345282 Binding of CASP1 and Pycard 1 0.01 0.3 0.03
139 INT274573 Positive_regulation of Binding of MEFV and PYCARD 1 0.09 0.06 0.03
140 INT327404 Binding of Xiap and Siva1 1 0.02 1.97 0.03
141 INT303056 Rorb Regulation of Bad 1 0.00 0.52 0.03
142 INT185856 Binding of BAD and BCL2L1 4 0.39 2.73 0
143 INT292454 Binding of BAD and BCL2 2 0.03 1.73 0
144 INT229815 Fos Regulation of Bad 1 0.09 0.31 0
145 INT325154 CDKN1B Negative_regulation of CCNE2 1 0.07 0.1 0
146 INT279798 APAF1 Positive_regulation of CASP3 1 0.01 1 0
147 INT336288 PYCARD Positive_regulation of SMN1 1 0.13 0 0
148 INT292444 BAD Positive_regulation of Phosphorylation of PTK2 1 0.13 0.9 0
149 INT215707 Cdkn2a Negative_regulation of Cdkn1b 1 0.01 0 0
150 INT292447 Negative_regulation of Binding of BAD and BCL2L1 1 0.02 0.81 0
151 INT246217 Cdkn1b Positive_regulation of VEGFA 1 0.03 1.13 0
152 INT185854 BID Positive_regulation of BAD 1 0.39 0.74 0
153 INT285909 AKT1 Regulation of Phosphorylation of Bad 1 0.01 0.4 0
154 INT104070 NLRP1 Positive_regulation of ISYNA1 1 0.10 0 0
155 INT302145 Positive_regulation of AKT1 Positive_regulation of Phosphorylation of BAD 1 0.07 0.9 0
156 INT166237 NLRP1 Positive_regulation of Localization of CD1D 1 0.48 0 0
157 INT325156 CDKN1B Negative_regulation of CDK2 1 0.49 0.11 0
158 INT349666 Binding of AR and PYCARD 1 0.06 0 0
159 INT302137 Binding of BAD and BAK1 1 0.07 0.93 0
160 INT292462 LAMB2 Positive_regulation of BAD 1 0.00 0.7 0
161 INT272867 Binding of NLRP1 and COPD 1 0.00 1.07 0
162 INT335953 Binding of BCL2 and Bad 1 0.14 0.37 0
163 INT279268 CARD8 Positive_regulation of CASP1 1 0.32 0.3 0
164 INT215697 Lamtor1 Negative_regulation of Cdkn1b 1 0.02 0 0
165 INT327970 GOPC Regulation of Gene_expression of BAD 1 0.08 0.6 0
166 INT345152 Binding of Lpar1 and Siva1 1 0.03 0.66 0
167 INT292458 Negative_regulation of Binding of BAD and BCL2 1 0.01 0.81 0
168 INT184952 NLRP1 Negative_regulation of Positive_regulation of MMP9 1 0.12 0.34 0
169 INT292459 Phosphorylation of BAD Negative_regulation of Binding of BCL2L1 1 0.02 0.82 0
170 INT295048 Bad Regulation of RYBP 1 0.00 1.64 0
171 INT292502 Mlph Regulation of Gene_expression of BAD 1 0.01 0.4 0
172 INT175400 RASGRP1 Positive_regulation of MAP3K5 1 0.00 1.2 0
173 INT172908 Binding of Bad and Bax 1 0.01 1.34 0
174 INT215682 Binding of Cdkn1b and Cdk6 1 0.03 0 0
175 INT354115 MIR222 Regulation of Gene_expression of CDKN1B 1 0.07 0.98 0
176 INT329745 AKT1 Negative_regulation of BAD 1 0.03 1.43 0
177 INT292508 Mlph Regulation of Phosphorylation of BAD 1 0.01 1.52 0
178 INT201760 Binding of BCL2L1 and Positive_regulation of Bad 1 0.01 0.3 0
179 INT261122 Binding of Tnfrsf10b and Tnfsf10 1 0.08 0.74 0
180 INT292501 Mlph Positive_regulation of Phosphorylation of BAD 1 0.01 0.39 0
181 INT335951 Binding of Bad and Tgif2lx1 1 0.00 0.37 0
182 INT302172 Binding of BAD and BAX 1 0.06 0.93 0
183 INT292457 PTK2 Regulation of BAD 1 0.03 0.76 0
184 INT215692 Stmn1 Negative_regulation of Cdkn1b 1 0.00 0 0
185 INT201756 CDKN1B Positive_regulation of Localization of Ccnd1 1 0.04 0 0
186 INT215694 Cdkn2b Negative_regulation of Cdkn1b 1 0.01 0 0
187 INT242612 Bcl10 Positive_regulation of Skull19 1 0.01 1.2 0
188 INT201743 Bad Positive_regulation of Positive_regulation of Bax 1 0.00 0.43 0
189 INT302132 Negative_regulation of Binding of BAD and BAK1 1 0.06 0.93 0
190 INT219634 Binding of NLRP1 and Slc22a6 1 0.26 0 0
191 INT193341 auditory Positive_regulation of CASP8AP2 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cysteine-type endopeptidase activator activity involved in apoptotic process. They are ordered first by their pain relevance and then by number of times they were reported in cysteine-type endopeptidase activator activity involved in apoptotic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT151758 Gene_expression of PYCARD 91 0.63 14.54 24.27
2 INT164366 Localization of NLRP1 26 0.71 5.9 16.54
3 INT145425 Positive_regulation of NLRP1 19 0.47 6.93 12.09
4 INT71174 Gene_expression of CASP1 44 0.75 30.3 9.37
5 INT97516 Binding of PYCARD 46 0.36 7.06 7.85
6 INT1766 Negative_regulation of PYCARD 25 0.37 6.54 6.76
7 INT13385 Gene_expression of Bad 60 0.76 41.86 6.52
8 INT13406 Negative_regulation of CASP1 25 0.57 10.61 6.36
9 INT137052 Positive_regulation of PYCARD 30 0.43 4.72 6.17
10 INT17641 Gene_expression of NLRP1 33 0.73 8.85 6.02
11 INT81049 Positive_regulation of CASP1 44 0.67 19.97 5.69
12 INT166765 Localization of PYCARD 21 0.70 3.89 5.66
13 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
14 INT108919 Positive_regulation of Mapk9 9 0.34 3.55 4.74
15 INT133231 Regulation of PYCARD 18 0.39 5.02 4.44
16 INT33229 Gene_expression of Bad 9 0.70 6.95 4.15
17 INT51654 Regulation of Bad 21 0.40 12.18 4.06
18 INT104480 Phosphorylation of Mapk9 8 0.80 6.59 3.62
19 INT125622 Regulation of NLRP1 7 0.44 1.84 3.62
20 INT3437 Negative_regulation of Bad 5 0.48 1.66 2.99
21 INT162792 Gene_expression of NOD1 19 0.71 6.11 2.71
22 INT257950 Regulation of Localization of NLRP1 3 0.08 0.27 2.6
23 INT29983 Localization of Bad 5 0.28 4.44 2.52
24 INT99548 Positive_regulation of Gene_expression of CDKN1B 12 0.67 6.79 2.5
25 INT164367 Negative_regulation of Localization of NLRP1 3 0.34 1.43 2.5
26 INT108333 Phosphorylation of BAD 43 0.68 33.77 2.45
27 INT111038 Gene_expression of Cdkn1b 23 0.75 25.35 2.22
28 INT95592 Positive_regulation of Gene_expression of CASP1 15 0.48 13.06 2.1
29 INT172874 Phosphorylation of Bad 31 0.80 27.46 2.07
30 INT142056 Binding of NLRP1 7 0.47 1.7 2.02
31 INT108921 Negative_regulation of Positive_regulation of Mapk9 3 0.25 1.8 1.99
32 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96
33 INT71173 Negative_regulation of Gene_expression of CASP1 5 0.36 3.17 1.84
34 INT43143 Binding of Bad 8 0.21 5.12 1.81
35 INT104478 Positive_regulation of Mapk9 5 0.67 5.56 1.81
36 INT104479 Negative_regulation of Mapk9 3 0.37 2.83 1.69
37 INT93427 Negative_regulation of Bad 4 0.02 2.5 1.63
38 INT142678 Positive_regulation of Phosphorylation of Mapk9 4 0.51 2.1 1.6
39 INT5855 Positive_regulation of Bad 12 0.61 12.26 1.56
40 INT119835 Positive_regulation of Gene_expression of BAD 6 0.44 7.66 1.51
41 INT216666 Positive_regulation of Localization of NLRP1 2 0.09 0.5 1.49
42 INT142676 Phosphorylation of Mapk9 5 0.61 1.48 1.48
43 INT18495 Regulation of Bad 6 0.19 4.79 1.45
44 INT95338 Positive_regulation of Positive_regulation of CASP1 9 0.49 4.61 1.43
45 INT126334 Gene_expression of Tnfrsf10b 8 0.58 8.68 1.42
46 INT119830 Gene_expression of BAD 24 0.50 20.05 1.41
47 INT159784 Gene_expression of Mapk9 8 0.61 6.28 1.37
48 INT142679 Negative_regulation of Phosphorylation of Mapk9 1 0.17 0.51 1.37
49 INT90226 Gene_expression of Mapk9 3 0.65 1.94 1.34
50 INT154081 Negative_regulation of Localization of Bad 2 0.16 2.06 1.31
51 INT160009 Transcription of CDKN1B 2 0.67 1.43 1.29
52 INT228328 Positive_regulation of Gene_expression of PYCARD 7 0.34 0.27 1.23
53 INT114220 Negative_regulation of Gene_expression of Cdkn1b 4 0.33 4.11 1.23
54 INT267652 Negative_regulation of Gene_expression of PYCARD 6 0.37 2.35 1.22
55 INT7817 Binding of CASP1 7 0.19 1.26 1.13
56 INT160008 Positive_regulation of Transcription of CDKN1B 1 0.49 0.98 1.1
57 INT128496 Regulation of CASP1 5 0.38 3.4 1.09
58 INT111036 Positive_regulation of Cdkn1b 16 0.45 9 1.06
59 INT111037 Positive_regulation of Gene_expression of Cdkn1b 5 0.39 11.17 1.06
60 INT140054 Negative_regulation of Mapk9 3 0.25 1.9 1.05
61 INT91658 Localization of CASP1 5 0.77 0.89 1.04
62 INT160012 Regulation of Gene_expression of CDKN1B 2 0.44 1.17 1.04
63 INT108340 Negative_regulation of Phosphorylation of BAD 11 0.49 8.29 1.02
64 INT307280 Regulation of Gene_expression of PYCARD 2 0.39 0.27 1.02
65 INT159668 Positive_regulation of Bad 8 0.45 6.32 0.89
66 INT108341 Positive_regulation of BAD 8 0.42 8.75 0.85
67 INT196583 Regulation of Phosphorylation of Mapk9 1 0.37 0.5 0.85
68 INT133767 Transcription of Bad 2 0.57 1.72 0.84
69 INT104482 Positive_regulation of Phosphorylation of Mapk9 2 0.49 1.55 0.84
70 INT228326 Positive_regulation of Localization of PYCARD 3 0.41 0 0.8
71 INT275180 Positive_regulation of Phosphorylation of Bad 4 0.40 3.79 0.77
72 INT84726 Gene_expression of NKX3-1 4 0.75 2.1 0.75
73 INT201628 Positive_regulation of Gene_expression of Bad 12 0.68 13.86 0.72
74 INT128497 Regulation of Gene_expression of CASP1 4 0.38 2.02 0.72
75 INT104488 Negative_regulation of Phosphorylation of Mapk9 1 0.41 1.03 0.72
76 INT285480 Transcription of Tnfrsf10b 1 0.02 3.68 0.69
77 INT153802 Positive_regulation of Localization of BAD 1 0.30 0.64 0.66
78 INT153799 Localization of BAD 1 0.45 0.63 0.66
79 INT331152 Positive_regulation of Localization of Bad 1 0.19 1.35 0.64
80 INT244153 Positive_regulation of Gene_expression of NOD1 1 0.46 1.36 0.63
81 INT331150 Negative_regulation of Gene_expression of Bad 1 0.10 1.33 0.63
82 INT244161 Positive_regulation of NOD1 4 0.64 1.83 0.62
83 INT241621 Regulation of Cdkn1b 2 0.06 0.36 0.62
84 INT113850 Negative_regulation of Cdkn1b 4 0.42 3.45 0.6
85 INT104483 Positive_regulation of Positive_regulation of Mapk9 1 0.49 0.75 0.56
86 INT108339 Positive_regulation of Phosphorylation of BAD 6 0.58 3.95 0.55
87 INT162791 Regulation of NOD1 2 0.13 0.58 0.55
88 INT150000 Positive_regulation of Positive_regulation of BAD 2 0.14 3.1 0.55
89 INT120358 Positive_regulation of Positive_regulation of CDKN1B 2 0.49 1.26 0.55
90 INT104484 Regulation of Mapk9 1 0.12 0.73 0.55
91 INT172876 Positive_regulation of Tnfrsf10b 3 0.03 3.66 0.54
92 INT179205 Regulation of Gene_expression of NLRP1 1 0.18 2.8 0.54
93 INT91661 Negative_regulation of Positive_regulation of CASP1 2 0.41 0.35 0.5
94 INT181281 Localization of NKX3-1 1 0.12 0.3 0.5
95 INT142871 Negative_regulation of Gene_expression of Bad 7 0.51 6.52 0.49
96 INT159667 Negative_regulation of Positive_regulation of Bad 4 0.20 3.13 0.48
97 INT115195 Negative_regulation of Localization of CASP1 1 0.16 0 0.48
98 INT105886 Phosphorylation of Bad 3 0.23 2.15 0.47
99 INT167975 Negative_regulation of Gene_expression of Mapk9 2 0.02 1.18 0.47
100 INT149999 Negative_regulation of Gene_expression of BAD 4 0.13 5.46 0.45
101 INT333195 Negative_regulation of Gene_expression of NLRP1 1 0.06 0.32 0.44
102 INT84724 Negative_regulation of Gene_expression of NKX3-1 1 0.41 0.43 0.44
103 INT172869 Positive_regulation of Gene_expression of Tnfrsf10b 3 0.08 3.88 0.4
104 INT91665 Positive_regulation of Localization of CASP1 2 0.48 0.27 0.4
105 INT94933 Positive_regulation of Gene_expression of Bcl10 1 0.01 1.74 0.38
106 INT294539 Binding of BAD 3 0.36 2.35 0.37
107 INT321424 Positive_regulation of MAP3K5 1 0.18 6.64 0.37
108 INT30049 Gene_expression of Bcl10 4 0.51 2.36 0.35
109 INT349671 Phosphorylation of PYCARD 1 0.33 0 0.35
110 INT342161 Positive_regulation of Gene_expression of Mapk9 1 0.09 0.63 0.35
111 INT204065 Regulation of Gene_expression of Cdkn1b 1 0.06 3.49 0.34
112 INT129153 Phosphorylation of CDKN1B 2 0.61 1.41 0.33
113 INT192983 Regulation of Regulation of Bad 1 0.01 0.3 0.33
114 INT228331 Positive_regulation of Negative_regulation of PYCARD 1 0.34 0 0.32
115 INT150396 Gene_expression of SIVA1 1 0.75 2.34 0.32
116 INT244143 Positive_regulation of Positive_regulation of NOD1 1 0.46 0.68 0.31
117 INT244171 Negative_regulation of NOD1 3 0.47 0 0.28
118 INT193357 Gene_expression of CASP8AP2 3 0.65 1 0.28
119 INT302274 Negative_regulation of Positive_regulation of BAD 1 0.13 1.31 0.27
120 INT135807 Positive_regulation of Negative_regulation of Bad 1 0.35 0.24 0.27
121 INT321428 Positive_regulation of Positive_regulation of MAP3K5 1 0.13 4.65 0.25
122 INT307281 Regulation of Regulation of PYCARD 1 0.30 0 0.24
123 INT338089 Negative_regulation of Regulation of PYCARD 1 0.35 0 0.24
124 INT318992 Localization of NOD1 1 0.11 1.1 0.23
125 INT154934 Negative_regulation of Positive_regulation of Mapk9 1 0.35 0.41 0.23
126 INT140059 Localization of Mapk9 1 0.28 0.61 0.23
127 INT233869 Binding of CDKN1B 2 0.47 0.46 0.22
128 INT179889 Negative_regulation of CDKN1B 4 0.57 1.71 0.21
129 INT222271 Transcription of NOD1 2 0.66 0.32 0.21
130 INT219633 Transcription of NLRP1 2 0.65 0.88 0.21
131 INT306296 Regulation of CDKN1B 1 0.19 0.46 0.21
132 INT172861 Negative_regulation of Tnfrsf10b 1 0.04 1.21 0.21
133 INT117107 Localization of Tnfrsf10b 1 0.68 0.17 0.2
134 INT117108 Regulation of Localization of Tnfrsf10b 1 0.26 0.17 0.2
135 INT117109 Regulation of Tnfrsf10b 1 0.44 0.17 0.2
136 INT206970 Negative_regulation of BAD 3 0.22 3.3 0.19
137 INT339342 Binding of NKX3-1 1 0.04 0.08 0.18
138 INT184993 Negative_regulation of NLRP1 7 0.41 2.1 0.17
139 INT201637 Regulation of Gene_expression of Bad 4 0.23 2.99 0.17
140 INT242278 Localization of SIVA1 1 0.01 1.07 0.17
141 INT242277 Positive_regulation of SIVA1 1 0.01 1.08 0.17
142 INT165361 Positive_regulation of APAF1 4 0.39 4.8 0.16
143 INT201689 Protein_catabolism of CDKN1B 3 0.96 0.7 0.16
144 INT273054 Positive_regulation of Binding of Bad 2 0.14 2.66 0.16
145 INT257863 Positive_regulation of Protein_catabolism of Cdkn1b 1 0.45 0.43 0.14
146 INT257865 Negative_regulation of Protein_catabolism of Cdkn1b 1 0.42 0.43 0.14
147 INT257858 Protein_catabolism of Cdkn1b 1 0.64 0.43 0.14
148 INT161613 Regulation of Phosphorylation of BAD 3 0.11 2.36 0.13
149 INT153486 Positive_regulation of Gene_expression of Bad 1 0.62 0.74 0.13
150 INT172857 Binding of Bad 2 0.36 2.86 0.12
151 INT244135 Positive_regulation of Negative_regulation of NLRP1 1 0.44 0 0.12
152 INT140057 Negative_regulation of Negative_regulation of Mapk9 1 0.15 0.31 0.12
153 INT140051 Negative_regulation of Localization of Mapk9 1 0.20 0.31 0.11
154 INT261118 Binding of Tnfrsf10b 3 0.07 4.03 0.1
155 INT162014 Protein_catabolism of Bad 1 0.76 0.29 0.1
156 INT233868 Localization of CDKN1B 2 0.73 0.37 0.09
157 INT190553 Regulation of Siva1 2 0.16 1.05 0.09
158 INT275179 Localization of Bad 2 0.69 0.66 0.09
159 INT165362 Gene_expression of APAF1 5 0.50 4.37 0.08
160 INT327394 Binding of Siva1 2 0.04 2.62 0.08
161 INT244155 Transcription of CARD8 1 0.36 0.05 0.08
162 INT165363 Positive_regulation of Positive_regulation of APAF1 1 0.28 1.12 0.08
163 INT178419 Regulation of Mapk9 1 0.09 0.76 0.08
164 INT233871 Negative_regulation of Protein_catabolism of CDKN1B 1 0.57 0.27 0.08
165 INT193813 Positive_regulation of Phosphorylation of APAF1 1 0.08 0.41 0.07
166 INT193808 Phosphorylation of APAF1 1 0.13 0.4 0.07
167 INT206969 Regulation of BAD 8 0.15 5.32 0.05
168 INT349674 Regulation of Positive_regulation of PYCARD 2 0.11 0.34 0.05
169 INT354591 Negative_regulation of Positive_regulation of PYCARD 1 0.05 0.34 0.05
170 INT244175 Gene_expression of CARD8 2 0.53 1.19 0.04
171 INT307913 Negative_regulation of Binding of PYCARD 1 0.37 0 0.04
172 INT274594 Positive_regulation of Binding of PYCARD 1 0.09 0.07 0.03
173 INT244158 Regulation of Gene_expression of NOD1 1 0.56 0 0.03
174 INT150397 Binding of SIVA1 1 0.36 0.46 0.03
175 INT215417 Gene_expression of MAP3K5 4 0.23 0.59 0
176 INT310236 Binding of APAF1 3 0.09 2.67 0
177 INT213908 Negative_regulation of MAP3K5 2 0.41 0.87 0
178 INT308398 Positive_regulation of Gene_expression of APAF1 2 0.39 1.8 0
179 INT292467 Regulation of Gene_expression of BAD 2 0.11 1.38 0
180 INT219631 Negative_regulation of Negative_regulation of NLRP1 1 0.27 0 0
181 INT190021 Negative_regulation of Gene_expression of Bcl10 1 0.32 0.77 0
182 INT325178 Regulation of Positive_regulation of CDKN1B 1 0.44 0.05 0
183 INT325180 Negative_regulation of Gene_expression of CDKN1B 1 0.57 0.25 0
184 INT193356 Phosphorylation of CASP8AP2 1 0.06 0.08 0
185 INT219630 Positive_regulation of Gene_expression of NLRP1 1 0.32 0 0
186 INT242531 Negative_regulation of Bcl10 1 0.02 1.09 0
187 INT343496 Negative_regulation of Gene_expression of NOD1 1 0.12 0 0
188 INT204070 Negative_regulation of Positive_regulation of Cdkn1b 1 0.05 0.47 0
189 INT244166 Negative_regulation of CARD8 1 0.29 0.37 0
190 INT279271 Positive_regulation of CARD8 1 0.33 0.3 0
191 INT193359 Positive_regulation of CASP8AP2 1 0.04 0.09 0
192 INT246216 Localization of Cdkn1b 1 0.42 0.22 0
193 INT175515 Regulation of Phosphorylation of Bad 1 0.08 1.69 0
194 INT244136 Transcription of CASP1 1 0.39 0.5 0
195 INT330030 Positive_regulation of Regulation of Bad 1 0.21 0.71 0
196 INT191676 Regulation of Gene_expression of Tnfrsf10b 1 0.02 1.34 0
197 INT270821 Regulation of Positive_regulation of CASP1 1 0.03 0 0
198 INT343493 Protein_catabolism of NOD1 1 0.25 0 0
199 INT246212 Positive_regulation of Positive_regulation of Cdkn1b 1 0.39 1.12 0
200 INT252739 Localization of MAP3K5 1 0.19 0.74 0
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