GO:0008757

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Name S-adenosylmethionine-dependent methyltransferase activity
Categary Function
Go Slim No
Go Link GO:0008757
Unique Molecular Interactions 30
Total Molecular Interactions 50
Total Single Events 344
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for S-adenosylmethionine-dependent methyltransferase activity. They are ordered first by their pain relevance and then by number of times they were reported for S-adenosylmethionine-dependent methyltransferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16382 Binding of Grin1 and Gnmt 1 0.04 0.17 0.32
2 INT130128 Binding of Ocln and Tjp1 2 0.38 0.98 0.29
3 INT83827 Negative_regulation of Binding of Adrb1 and Pnmt 1 0.02 0 0.1
4 INT83828 Binding of Adrb1 and Pnmt 1 0.01 0 0.1
5 INT265346 Binding of Ocln and Tjp1 7 0.05 1.11 0.09
6 INT66171 Negative_regulation of Adra2a Negative_regulation of Positive_regulation of Pnmt 1 0.38 0 0.08
7 INT205244 Cldn3 Regulation of Gene_expression of Ocln 1 0.04 0.29 0.07
8 INT205229 Cldn2 Regulation of Gene_expression of Ocln 1 0.07 0.29 0.07
9 INT66166 Negative_regulation of Binding of Pnmt and Adra2a 1 0.38 0 0.07
10 INT205233 Cldn5 Regulation of Gene_expression of Ocln 1 0.03 0.28 0.07
11 INT66167 Negative_regulation of Pnmt Negative_regulation of Adra2a 1 0.38 0 0.07
12 INT66172 Binding of Pnmt and Adra2a 1 0.33 0 0.07
13 INT265564 Ocln Regulation of Gene_expression of Cdh5 1 0.01 1.03 0.05
14 INT355224 Phosphorylation of Ocln Negative_regulation of Binding of Tjp2 1 0.06 0.09 0.04
15 INT355219 Phosphorylation of Ocln Positive_regulation of Binding of Tjp2 1 0.07 0.09 0.04
16 INT305875 Pcx Negative_regulation of Binding of Ocln 1 0.03 0.11 0.04
17 INT265347 Binding of Ocln and Tgfbr1 1 0.18 0.06 0.03
18 INT332938 Suv39h1 Positive_regulation of Hist1h3f 1 0.06 0.12 0.03
19 INT265348 Positive_regulation of Binding of Ocln and Tgfbr1 1 0.25 0.06 0.03
20 INT355220 Negative_regulation of Binding of Ocln and Tjp1 1 0.21 0.14 0
21 INT305879 Binding of Ocln and Pcx 1 0.03 0 0
22 INT305881 Positive_regulation of Binding of Ocln and Tjp1 1 0.01 0 0
23 INT245821 Binding of Ppp2r2b and Ocln 1 0.00 0.81 0
24 INT297690 Binding of Fut1 and Ocln 1 0.02 0 0
25 INT355221 Binding of Espn and Ocln 1 0.01 0 0
26 INT245832 VEGFA Positive_regulation of Phosphorylation of Ocln 1 0.04 1.61 0
27 INT245830 VEGFA Regulation of Ocln 1 0.02 0.83 0
28 INT355225 Binding of Ocln and Tjp2 1 0.07 0 0
29 INT355222 Positive_regulation of Binding of Ocln and Tjp1 1 0.18 0 0
30 INT245824 Plg Regulation of Negative_regulation of Ocln 1 0.06 0.57 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for S-adenosylmethionine-dependent methyltransferase activity. They are ordered first by their pain relevance and then by number of times they were reported in S-adenosylmethionine-dependent methyltransferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT18539 Gene_expression of Pnmt 33 0.78 3.08 12.47
2 INT3922 Negative_regulation of Pnmt 29 0.59 3.18 8.96
3 INT23132 Positive_regulation of Pnmt 17 0.67 2.02 6.84
4 INT105284 Gene_expression of Ocln 39 0.78 14.98 5.08
5 INT14455 Transcription of Pnmt 17 0.72 2.13 4.95
6 INT12380 Localization of Pnmt 10 0.80 0.07 4.7
7 INT18538 Regulation of Pnmt 11 0.60 1.03 3.84
8 INT28468 Positive_regulation of Transcription of Pnmt 4 0.67 0.63 2.04
9 INT124077 Negative_regulation of Ocln 13 0.57 8.62 1.8
10 INT28478 Regulation of Gene_expression of Pnmt 5 0.44 0 1.41
11 INT105286 Negative_regulation of Gene_expression of Ocln 7 0.31 2.52 1.35
12 INT28469 Positive_regulation of Gene_expression of Pnmt 4 0.49 0.73 1.11
13 INT125904 Positive_regulation of Ocln 6 0.45 2.06 1.06
14 INT47518 Negative_regulation of Positive_regulation of Pnmt 2 0.42 0.32 0.8
15 INT245796 Phosphorylation of Ocln 6 0.33 2.76 0.76
16 INT12379 Regulation of Localization of Pnmt 1 0.17 0 0.69
17 INT159143 Gene_expression of Ocln 14 0.42 5.25 0.57
18 INT158898 Positive_regulation of Gene_expression of Ocln 5 0.22 2.06 0.57
19 INT304633 Positive_regulation of Phosphorylation of Ocln 2 0.28 0.19 0.47
20 INT61822 Negative_regulation of Ocln 8 0.41 5.33 0.45
21 INT159145 Negative_regulation of Gene_expression of Ocln 4 0.32 3.07 0.34
22 INT124076 Binding of Ocln 3 0.37 1.01 0.34
23 INT16380 Positive_regulation of Gnmt 1 0.05 0.25 0.33
24 INT205218 Localization of Ocln 3 0.46 1.71 0.32
25 INT83525 Negative_regulation of Transcription of Pnmt 3 0.57 0 0.27
26 INT217515 Binding of Ocln 7 0.22 2.12 0.25
27 INT83526 Negative_regulation of Gene_expression of Pnmt 1 0.41 0 0.25
28 INT61818 Positive_regulation of Ocln 6 0.23 4.11 0.22
29 INT245799 Protein_catabolism of Ocln 2 0.62 1.78 0.22
30 INT245798 Positive_regulation of Negative_regulation of Ocln 2 0.27 1.9 0.22
31 INT300430 Negative_regulation of Phosphorylation of Ocln 1 0.19 0.43 0.21
32 INT291082 Positive_regulation of Protein_catabolism of Ocln 1 0.31 0.96 0.2
33 INT291080 Negative_regulation of Protein_catabolism of Ocln 1 0.26 0.96 0.2
34 INT130125 Regulation of Ocln 5 0.44 0.87 0.19
35 INT16756 Regulation of Transcription of Pnmt 2 0.39 0.08 0.18
36 INT159142 Regulation of Gene_expression of Ocln 3 0.25 1.36 0.16
37 INT217500 Phosphorylation of Ocln 1 0.24 0.96 0.13
38 INT205210 Transcription of Ocln 2 0.32 0.58 0.11
39 INT159144 Positive_regulation of Gene_expression of Ocln 1 0.27 1.04 0.09
40 INT66162 Positive_regulation of Binding of Pnmt 1 0.49 0 0.08
41 INT61820 Positive_regulation of Negative_regulation of Ocln 1 0.15 1.65 0.08
42 INT66164 Negative_regulation of Binding of Pnmt 1 0.41 0 0.08
43 INT66163 Binding of Pnmt 1 0.36 0 0.08
44 INT217516 Negative_regulation of Phosphorylation of Ocln 1 0.17 0.77 0.07
45 INT217502 Positive_regulation of Phosphorylation of Ocln 1 0.13 0.19 0.06
46 INT303527 Transcription of Ocln 1 0.20 0.35 0.06
47 INT265559 Regulation of Gene_expression of Ocln 2 0.13 1.01 0.04
48 INT355217 Negative_regulation of Binding of Ocln 1 0.27 0.21 0.04
49 INT332918 Localization of Suv39h1 1 0.73 0.11 0.03
50 INT245802 Negative_regulation of Negative_regulation of Ocln 1 0.10 0.89 0.03
51 INT217513 Positive_regulation of Positive_regulation of Ocln 1 0.15 0.66 0.03
52 INT265322 Positive_regulation of Binding of Ocln 3 0.23 0.3 0
53 INT265325 Regulation of Ocln 2 0.18 0.07 0
54 INT265333 Localization of Ocln 2 0.34 0 0
55 INT305873 Regulation of Localization of Ocln 1 0.06 0 0
56 INT265336 Positive_regulation of Localization of Ocln 1 0.23 0 0
57 INT76171 Regulation of Regulation of Pnmt 1 0.19 0 0
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