GO:0009008

From wiki-pain
Jump to: navigation, search
Name DNA-methyltransferase activity
Categary Function
Go Slim No
Go Link GO:0009008
Unique Molecular Interactions 24
Total Molecular Interactions 30
Total Single Events 190
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA-methyltransferase activity. They are ordered first by their pain relevance and then by number of times they were reported for DNA-methyltransferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73116 TYMS Negative_regulation of DNMT3B 1 0.24 0 1.6
2 INT73115 TYMS Negative_regulation of Positive_regulation of DNMT3B 1 0.24 0 1.6
3 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
4 INT150793 ZNF398 Negative_regulation of Gene_expression of DNMT1 1 0.07 0.46 0.48
5 INT285718 Binding of DNMT3B and Lbp 1 0.08 0.33 0.33
6 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25
7 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
8 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
9 INT254770 Regulation of Binding of DNMT1 and Igh-Dex 1 0.00 0 0.22
10 INT254771 Binding of DNMT1 and Igh-Dex 1 0.00 0 0.19
11 INT228610 Binding of DNMT3B and ASPRV1 1 0.02 0 0.05
12 INT241268 DNMT3B Positive_regulation of Gene_expression of DNMT1 1 0.19 0.67 0
13 INT284918 RUNX1T1 Regulation of DNMT1 1 0.21 1.09 0
14 INT241266 DNMT3B Positive_regulation of Gene_expression of GOPC 1 0.05 0.68 0
15 INT241264 DNMT1 Positive_regulation of Gene_expression of DNMT3B 1 0.19 0.67 0
16 INT241257 DNMT3B Positive_regulation of OPCML 1 0.35 0.68 0
17 INT241259 DNMT3B Positive_regulation of GOPC 1 0.05 0.68 0
18 INT253331 Binding of DNMT3B and SP140 1 0.04 0.17 0
19 INT241265 DNMT1 Positive_regulation of OPCML 1 0.31 0.68 0
20 INT241269 DNMT1 Positive_regulation of Gene_expression of GOPC 1 0.04 0.68 0
21 INT191135 Binding of DNMT3A and DNMT3B 1 0.09 0 0
22 INT241254 DNMT1 Positive_regulation of GOPC 1 0.04 0.68 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA-methyltransferase activity. They are ordered first by their pain relevance and then by number of times they were reported in DNA-methyltransferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73117 Positive_regulation of DNMT3B 20 0.47 10.31 5.31
2 INT103350 Gene_expression of DNMT1 15 0.67 9.77 3.83
3 INT136106 Gene_expression of DNMT3B 30 0.58 8.43 3.7
4 INT121531 Negative_regulation of DNMT3B 13 0.36 3.46 3.05
5 INT133038 Binding of DNMT3B 26 0.40 5.97 2.83
6 INT157500 Localization of DNMT3B 12 0.73 2.21 1.38
7 INT46336 Regulation of DNMT3B 12 0.53 4.91 1.25
8 INT322088 Regulation of Regulation of DNMT3B 1 0.03 2.74 1.12
9 INT285716 Negative_regulation of Gene_expression of DNMT3B 1 0.21 0.96 0.96
10 INT201859 Positive_regulation of Gene_expression of DNMT1 4 0.60 6.43 0.75
11 INT241287 Positive_regulation of Gene_expression of DNMT3B 3 0.40 1.21 0.57
12 INT146400 Positive_regulation of DNMT1 4 0.45 0.91 0.43
13 INT254763 Localization of DNMT1 1 0.05 0.2 0.29
14 INT284938 Regulation of DNMT1 2 0.22 1.17 0.24
15 INT191163 Transcription of DNMT3B 4 0.50 0.46 0.13
16 INT258077 Negative_regulation of Gene_expression of DNMT1 2 0.30 1.27 0.12
17 INT258063 Negative_regulation of DNMT1 3 0.28 1.36 0.11
18 INT254762 Positive_regulation of Positive_regulation of DNMT1 1 0.04 0 0.09
19 INT292609 Negative_regulation of Positive_regulation of DNMT3B 1 0.22 1.3 0.07
20 INT284977 Binding of DNMT1 3 0.17 0.86 0
21 INT284945 Protein_catabolism of DNMT1 2 0.32 0.47 0
22 INT191157 Negative_regulation of Transcription of DNMT3B 1 0.19 0.06 0
23 INT185991 Regulation of Gene_expression of DNMT3B 1 0.37 0 0
24 INT284993 Positive_regulation of Protein_catabolism of DNMT1 1 0.22 0.26 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox