GO:0009055

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Name electron carrier activity
Categary Function
Go Slim No
Go Link GO:0009055
Unique Molecular Interactions 862
Total Molecular Interactions 1100
Total Single Events 10956
Pain Genes Associated 129

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for electron carrier activity. They are ordered first by their pain relevance and then by number of times they were reported for electron carrier activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT349583 Aap Positive_regulation of Gene_expression of Cyp2e1 1 0.18 1.57 3.59
2 INT349584 Binding of Cyp2e1 and Aap 1 0.10 1.56 3.24
3 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84
4 INT349589 Aap Positive_regulation of Cyp2e1 1 0.21 1.84 2.71
5 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2
6 INT53751 Positive_regulation of Cyp2e1 Positive_regulation of RYBP 1 0.14 0.89 1.98
7 INT129903 Nr1i2 Regulation of Cyp3a11 1 0.64 1.26 1.9
8 INT37840 Binding of Cyp27b1 and Oprd1 1 0.01 0 1.73
9 INT92369 Binding of CYP2D6 and RYBP 1 0.25 0.15 1.73
10 INT100784 RYBP Positive_regulation of CYP3A4 1 0.44 0 1.54
11 INT123899 Binding of CYP3A4 and UGT2B7 1 0.52 0 1.46
12 INT29599 Binding of Cyp21a1 and Adarb1 1 0.01 0 1.38
13 INT90221 Binding of CYP2D6 and Cyp1a2 1 0.03 0.09 1.31
14 INT86518 Ass1 Positive_regulation of Hmox2 1 0.03 0.08 1.27
15 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 0.47 0.88 1.26
16 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2
17 INT142075 IL4 Negative_regulation of Binding of IDO1 1 0.02 2.07 1.19
18 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
19 INT264988 Binding of CYP2C19 and CYP3A4 1 0.18 0.72 1.09
20 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
21 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
22 INT28186 CYP2E1 Regulation of Positive_regulation of RYBP 1 0.04 0.33 1.08
23 INT264987 Binding of CYP2C9 and CYP3A4 1 0.19 0.71 1.08
24 INT81583 Cyp3a23/3a1 Positive_regulation of st 1 0.04 0 1.08
25 INT81580 Cyp3a23/3a1 Positive_regulation of Nudt14 1 0.01 0 1.08
26 INT77083 Das Negative_regulation of Cyp2e1 1 0.20 0.59 1.06
27 INT154237 Binding of CYP2D6 and Ugt2b7 1 0.41 0.75 1
28 INT53750 Cyp2e1 Positive_regulation of RYBP 1 0.14 0.44 0.99
29 INT349592 GTF2H5 Negative_regulation of Cyp2c22 1 0.00 0.64 0.98
30 INT119276 Negative_regulation of CYBB Negative_regulation of Positive_regulation of ROS1 1 0.09 1.18 0.97
31 INT119275 Negative_regulation of CYBB Negative_regulation of Gene_expression of ROS1 1 0.09 1.18 0.97
32 INT155985 Nfkb1 Negative_regulation of Gene_expression of Cyp11a1 1 0.10 0.53 0.95
33 INT52806 CYP2E1 Positive_regulation of RYBP 1 0.43 0.24 0.95
34 INT130282 Cyp3a23/3a1 Positive_regulation of Gene_expression of Npy 1 0.15 0 0.94
35 INT68799 Cyp3a62 Negative_regulation of Cyp2d1 1 0.35 0 0.91
36 INT279166 Binding of Cyp3a23/3a1 and Nr3c2 1 0.00 0.61 0.9
37 INT56274 RYBP Negative_regulation of Cyp2e1 1 0.01 0.17 0.9
38 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
39 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
40 INT56273 RYBP Negative_regulation of Cyp1a2 1 0.01 0.17 0.9
41 INT28194 Nppb Positive_regulation of CYP2B6 1 0.50 0.05 0.88
42 INT119274 CYBB Positive_regulation of ROS1 1 0.11 1.11 0.88
43 INT37839 Positive_regulation of Binding of Cyp27b1 and Oprd1 1 0.01 0 0.86
44 INT136540 Binding of CYP2C9 and Ugt1a6a 1 0.27 0.81 0.86
45 INT253995 Binding of Cxcl12 and Cyp3a23/3a1 1 0.06 1.28 0.85
46 INT100283 TXN Negative_regulation of Gene_expression of POMC 1 0.54 0.5 0.85
47 INT243678 Binding of GSR and Ugcg 2 0.03 2.84 0.83
48 INT48751 Binding of Nqo1 and Npy 1 0.28 0 0.82
49 INT28185 CYP2B6 Positive_regulation of Positive_regulation of RYBP 1 0.29 0 0.82
50 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
51 INT56275 RYBP Positive_regulation of Negative_regulation of Cyp1a2 1 0.01 0.17 0.81
52 INT102630 Cyp3a62 Negative_regulation of Cyp1a2 1 0.40 0 0.81
53 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81
54 INT92372 CYP2B6 Positive_regulation of Binding of RYBP 1 0.17 0.09 0.81
55 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8
56 INT144449 Plscr1 Positive_regulation of Gene_expression of Nqo1 1 0.15 0.18 0.8
57 INT144451 Napa Positive_regulation of Gene_expression of Nqo1 1 0.07 0.18 0.8
58 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
59 INT130283 Cyp3a23/3a1 Positive_regulation of Transcription of Npy 1 0.10 0 0.79
60 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77
61 INT56272 Cyp2e1 Positive_regulation of Cyp1a2 1 0.52 0.17 0.77
62 INT28187 CYP2B6 Positive_regulation of RYBP 1 0.31 0.35 0.76
63 INT178576 CNTN2 Positive_regulation of DPYD 1 0.05 2.18 0.76
64 INT90959 PPIG Regulation of CYP2C9 1 0.43 0 0.75
65 INT88921 Positive_regulation of CYP2D6 Negative_regulation of ANTXR1 1 0.00 0.8 0.75
66 INT88922 CYP2D6 Negative_regulation of ANTXR1 1 0.00 0.8 0.75
67 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
68 INT218933 Cyp3a23/3a1 Regulation of Alpi 1 0.00 1.07 0.73
69 INT92370 Binding of CYP2B6 and CYP2D6 1 0.21 0 0.73
70 INT38512 Binding of Cyp2c22 and Atp6v1c2 1 0.00 0.17 0.73
71 INT186674 Binding of BGLAP and CYP27A1 1 0.01 1.91 0.71
72 INT28184 Binding of CYP1A2 and CYP2D6 1 0.00 0 0.7
73 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
74 INT26230 Binding of GSR and HTR1D 1 0.12 0.15 0.69
75 INT26231 Binding of GSR and HTR1B 1 0.12 0.15 0.66
76 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
77 INT86519 Binding of Hmox1 and Hmox2 1 0.08 0.1 0.66
78 INT113685 Binding of Cyp3a23/3a1 and Cyp2c11 1 0.35 0 0.65
79 INT76026 Binding of Cyp2e1 and Cyp3a11 1 0.28 0.42 0.64
80 INT135471 Binding of CYP2B6 and UGT2B7 1 0.49 0 0.63
81 INT351276 CYP2D6 Regulation of CYP1A2 1 0.12 0 0.63
82 INT112032 Positive_regulation of Oprm1 Positive_regulation of Pdia3 1 0.44 0.13 0.62
83 INT330984 Negative_regulation of CYP2D6 Positive_regulation of Localization of CYP1A2 1 0.46 0 0.62
84 INT158362 Tnf Positive_regulation of Steap4 1 0.55 1.6 0.61
85 INT149929 Cyp2e1 Positive_regulation of Gene_expression of Ros1 1 0.12 0 0.61
86 INT37555 FDX1 Positive_regulation of Regulation of Avp 1 0.04 0 0.61
87 INT96228 COX5A Regulation of Ak1 1 0.01 0.6 0.6
88 INT52816 Cyp3a23/3a1 Regulation of Localization of LH 1 0.03 0.16 0.6
89 INT315334 Binding of CYP3A4 and CDIPT 3 0.04 0.85 0.59
90 INT43692 Cyp3a23/3a1 Negative_regulation of Gh1 1 0.04 0 0.59
91 INT102670 Cyp2e1 Regulation of RYBP 1 0.01 0 0.58
92 INT5416 Negative_regulation of Penk Positive_regulation of Pdia4 1 0.03 0.09 0.58
93 INT102671 Cyp1a2 Regulation of RYBP 1 0.00 0 0.58
94 INT102666 Cyp2e1 Regulation of Cyp1a2 1 0.20 0 0.58
95 INT172133 IL4 Negative_regulation of Gene_expression of HMOX2 1 0.00 0.81 0.58
96 INT347362 RYBP Regulation of Gene_expression of GSR 1 0.01 0 0.57
97 INT43693 Cyp3a23/3a1 Positive_regulation of Localization of Prl 1 0.10 0 0.57
98 INT148922 Pdia4 Negative_regulation of Tnf 1 0.09 1.01 0.56
99 INT73920 Binding of CCNT1 and CYP2B6 1 0.19 0.17 0.56
100 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55
101 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55
102 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
103 INT147579 Binding of ATF4 and Cyp1a1 1 0.01 0.15 0.54
104 INT123896 CYP2B6 Regulation of UGT2B7 1 0.42 0 0.53
105 INT5417 Penk Positive_regulation of Pdia4 1 0.03 0.09 0.52
106 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
107 INT347369 RYBP Positive_regulation of GSR 1 0.01 0.43 0.51
108 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
109 INT12897 Penk Regulation of Pdia4 1 0.07 0 0.5
110 INT330107 Racgap1 Regulation of Positive_regulation of Nox3 1 0.01 0.87 0.49
111 INT121944 Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.78 0.43 0.49
112 INT145433 Binding of CPOX and HMOX2 1 0.01 0.42 0.49
113 INT340110 MAOB Positive_regulation of Ltp 1 0.02 0.59 0.49
114 INT92803 Binding of CYP1A2 and VKORC1 1 0.31 0.12 0.48
115 INT210160 Binding of TNFRSF8 and TXN 1 0.47 4.16 0.48
116 INT347367 RYBP Negative_regulation of GSR 1 0.01 0.09 0.48
117 INT92804 Positive_regulation of Binding of CYP1A2 and VKORC1 1 0.41 0.12 0.48
118 INT347364 RYBP Regulation of GSR 1 0.01 0.06 0.48
119 INT162329 Tmc1 Negative_regulation of Gene_expression of Ptges2 1 0.03 0.58 0.47
120 INT92801 Binding of CYP2B6 and GRHPR 1 0.03 0.1 0.47
121 INT145436 Binding of HMOX2 and PTGS2 1 0.02 0.41 0.47
122 INT162932 TXNRD1 Negative_regulation of Phosphorylation of AKT1 1 0.14 1.01 0.47
123 INT281982 Cyp3a23/3a1 Negative_regulation of Gene_expression of MDK 1 0.00 0.67 0.47
124 INT330108 Racgap1 Positive_regulation of Cybb 1 0.03 0.86 0.46
125 INT103027 Ptgis Positive_regulation of Nos3 1 0.06 0.42 0.46
126 INT149690 M1 Negative_regulation of CYP2C8 1 0.19 0.05 0.46
127 INT162929 NQO1 Negative_regulation of Phosphorylation of AKT1 1 0.41 1 0.46
128 INT103026 Ptgis Positive_regulation of Ptgs1 1 0.02 0.42 0.46
129 INT218932 Cyp3a23/3a1 Regulation of Gene_expression of Alpi 1 0.00 0.53 0.46
130 INT113113 COX5A Regulation of Gene_expression of MRXS5 1 0.10 0.9 0.45
131 INT123897 Binding of CYP3A4 and SLC35A2 1 0.39 0 0.45
132 INT136749 COX5A Positive_regulation of Gene_expression of SCARB1 1 0.52 0.36 0.45
133 INT262155 Nr5a2 Positive_regulation of Cyp7a1 1 0.07 0.24 0.45
134 INT208910 Ubl4 Regulation of Regulation of FDX1 1 0.01 0.85 0.45
135 INT103028 Calca Positive_regulation of Gene_expression of Ptgis 1 0.17 0.58 0.44
136 INT151637 Binding of Cyp21a1 and Ear11 1 0.01 0 0.44
137 INT342998 DUOX1 Positive_regulation of ROS1 1 0.23 0.25 0.43
138 INT100282 TXN Negative_regulation of Transcription of POMC 1 0.54 0.39 0.43
139 INT115915 AHR Regulation of Gene_expression of CYP2B6 1 0.06 0.36 0.43
140 INT168435 Positive_regulation of Binding of GLRX and Gpx1 1 0.05 0.91 0.42
141 INT168434 Binding of GLRX and Gpx1 1 0.04 0.9 0.42
142 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
143 INT17726 Positive_regulation of Binding of AKR1A1 and Aldh2 1 0.11 0.35 0.41
144 INT123898 CYP3A4 Regulation of UGT2B7 1 0.22 0 0.41
145 INT320810 Protein_catabolism of COL1A2 Positive_regulation of Localization of CYP27A1 1 0.04 1.05 0.4
146 INT61660 Binding of CHAT and CYP21A2 1 0.00 0 0.4
147 INT17725 Binding of AKR1A1 and Aldh2 1 0.08 0.35 0.4
148 INT262186 Nr0b2 Positive_regulation of Negative_regulation of Cyp7a1 1 0.12 0.28 0.4
149 INT262205 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.33 0.11 0.38
150 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36
151 INT69468 CYP2B6 Positive_regulation of Localization of CYP3A 1 0.25 0 0.36
152 INT69467 CYP2E1 Positive_regulation of Localization of CYP3A 1 0.30 0 0.36
153 INT69469 CYP2E1 Positive_regulation of CYP2B6 1 0.36 0 0.36
154 INT187064 ARSD Negative_regulation of CYP19A1 1 0.22 0.7 0.35
155 INT159903 Binding of CYP2C8 and CYP2C9 1 0.42 0.22 0.35
156 INT105768 Binding of Nos1 and Nqo1 1 0.00 0.26 0.34
157 INT183780 INS Negative_regulation of Gene_expression of CYBB 1 0.02 1.74 0.34
158 INT144448 Nqo1 Regulation of Nos1 1 0.11 0.09 0.34
159 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34
160 INT144450 Regulation of Nqo1 Regulation of Nos1 1 0.11 0.1 0.34
161 INT51480 Gtpc Positive_regulation of Pdia4 1 0.04 0 0.34
162 INT37554 Avp Regulation of FDX1 1 0.01 0 0.34
163 INT37553 Crh Regulation of FDX1 1 0.03 0 0.34
164 INT241742 Negative_regulation of Sdhb Regulation of Rapgef5 1 0.02 0.39 0.33
165 INT83348 GSR Negative_regulation of JUND 1 0.20 0.72 0.33
166 INT83347 GSR Negative_regulation of NFKB1 1 0.25 0.72 0.33
167 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
168 INT263090 Negative_regulation of Binding of FDX1 and LH 1 0.02 0.95 0.32
169 INT263091 Binding of FDX1 and LH 1 0.02 0.95 0.32
170 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.97 0.32
171 INT235971 Positive_regulation of Binding of Nqo1 and NMO-IgG 1 0.00 1.86 0.32
172 INT78064 Cyp3a23/3a1 Regulation of Localization of Il6 1 0.08 0.07 0.32
173 INT241740 Sdhb Regulation of Rapgef5 1 0.02 0.34 0.32
174 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31
175 INT336936 Binding of GSR and Nr3c2 1 0.06 2.29 0.31
176 INT147445 Pscs Positive_regulation of Gene_expression of CYBB 1 0.02 0.33 0.31
177 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
178 INT294115 IDO1 Positive_regulation of PTGER2 1 0.02 0.36 0.31
179 INT269064 Il6 Positive_regulation of Gene_expression of Cybb 1 0.75 0.79 0.31
180 INT187603 Binding of Ptgis and Ppara 1 0.00 0.26 0.31
181 INT26235 Binding of GSR and Htr1a 1 0.12 0.09 0.31
182 INT241739 Sdhb Regulation of Adora2b 1 0.04 0.63 0.31
183 INT207355 ZNF398 Regulation of CYP27A1 1 0.00 0 0.31
184 INT242399 Cyp19a1 Negative_regulation of Gene_expression of Bad 1 0.00 1.32 0.31
185 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
186 INT139044 AKR1B1 Regulation of Gene_expression of PTGS2 1 0.09 0.37 0.3
187 INT66243 KNG1 Positive_regulation of Ptgis 1 0.01 0 0.3
188 INT132984 CYP3A4 Positive_regulation of Gene_expression of PPP4C 1 0.44 0 0.3
189 INT55269 Cp Negative_regulation of Cyb5a 1 0.01 0.54 0.3
190 INT281970 Cyp3a23/3a1 Negative_regulation of Gene_expression of Tie1 1 0.00 0.46 0.3
191 INT118239 Binding of CCKAR and CYP2B6 1 0.32 0.19 0.29
192 INT59684 Binding of Gmfb and Cyp2c6 1 0.00 0 0.29
193 INT137683 Positive_regulation of Binding of Cyp27b1 and Prkca 1 0.03 0 0.29
194 INT137684 Binding of Cyp27b1 and Prkca 1 0.02 0 0.29
195 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28
196 INT134927 CYP19A1 Positive_regulation of Gene_expression of MME 1 0.30 1.04 0.28
197 INT218934 Cyp3a23/3a1 Negative_regulation of Ephb1 1 0.01 0.95 0.28
198 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28
199 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
200 INT5935 Por Regulation of Oprm1 1 0.19 0.51 0.28

Single Events

The table below shows the top 100 pain related interactions that have been reported for electron carrier activity. They are ordered first by their pain relevance and then by number of times they were reported in electron carrier activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91
2 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51
3 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39
4 INT56870 Gene_expression of CYP2D6 87 0.78 8.83 37.53
5 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27
6 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83
7 INT20307 Positive_regulation of Cyp2e1 70 0.70 23.59 32.49
8 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16
9 INT16814 Negative_regulation of COX5A 74 0.57 33.72 28.63
10 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27
11 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6
12 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6
13 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21
14 INT39914 Negative_regulation of Cyp1a2 44 0.58 10.04 22
15 INT47859 Negative_regulation of Cyp2e1 41 0.59 16.92 21.72
16 INT8765 Positive_regulation of Cyp3a23/3a1 63 0.67 22.28 20.39
17 INT20305 Gene_expression of Cyp2e1 53 0.78 19.75 19.54
18 INT68347 Negative_regulation of Cyp2d4 34 0.58 7.62 18.35
19 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26
20 INT14111 Positive_regulation of Cyp2c22 41 0.67 7.24 17.88
21 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79
22 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45
23 INT50404 Negative_regulation of CYP1A2 49 0.59 8.61 17.35
24 INT134298 Gene_expression of Ptges2 96 0.54 56.52 17.19
25 INT20336 Positive_regulation of CYP2E1 48 0.70 19.26 15.66
26 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39
27 INT32706 Gene_expression of Cyp3a23/3a1 51 0.65 19.48 15.06
28 INT9904 Gene_expression of CYP2E1 64 0.78 13.11 14.65
29 INT39507 Positive_regulation of TXNRD1 37 0.68 12.47 14.25
30 INT19408 Negative_regulation of Cyp2c22 37 0.59 6.23 14.22
31 INT53747 Positive_regulation of Cyp2e1 34 0.70 29.03 13.39
32 INT18191 Negative_regulation of Cyp3a23/3a1 48 0.57 10.21 13.38
33 INT28014 Localization of Cyp3a23/3a1 34 0.77 9.8 12.96
34 INT635 Negative_regulation of MAOB 51 0.59 24.5 12.66
35 INT116433 Gene_expression of CYBB 93 0.70 50.44 11.91
36 INT10798 Positive_regulation of CYP2D6 24 0.56 5.82 11.31
37 INT3845 Gene_expression of GSR 79 0.76 44.69 11.19
38 INT71189 Gene_expression of Cyp1a2 24 0.78 11.39 11.12
39 INT10384 Positive_regulation of Nqo1 62 0.70 14.27 11.08
40 INT62580 Gene_expression of Cyp2e1 31 0.78 15.4 11.08
41 INT83886 Negative_regulation of HMOX2 27 0.43 11.69 10.78
42 INT22210 Gene_expression of CYP1A2 45 0.78 4.95 10.66
43 INT84077 Gene_expression of Hmox2 18 0.77 6.41 10.66
44 INT41627 Gene_expression of Nqo1 33 0.65 4.58 10.48
45 INT55418 Regulation of CYP2D6 29 0.61 1.83 10.21
46 INT19132 Gene_expression of CYP27A1 83 0.75 34.31 10.17
47 INT47860 Negative_regulation of Cyp1a2 20 0.57 6.06 10
48 INT68372 Regulation of CYP2C9 28 0.62 5.64 9.53
49 INT53746 Regulation of Cyp2e1 11 0.62 3.82 9.52
50 INT3846 Positive_regulation of GSR 60 0.50 35.16 9.37
51 INT57665 Negative_regulation of Cyp2e1 35 0.59 8.05 9.29
52 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28
53 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21
54 INT10597 Gene_expression of Cyp19a1 27 0.78 7.48 9.11
55 INT107087 Positive_regulation of Gene_expression of Cyp2e1 20 0.70 8.89 9.04
56 INT66819 Binding of CYP2C9 41 0.48 8.23 8.76
57 INT140411 Gene_expression of Nqo1 45 0.60 62.35 8.7
58 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34
59 INT61599 Positive_regulation of CYP2C9 43 0.69 11.1 8.33
60 INT5114 Gene_expression of Ptgis 41 0.50 21.43 8.1
61 INT22056 Positive_regulation of CYBB 88 0.68 32.13 7.95
62 INT173808 Positive_regulation of CYP27A1 35 0.68 23.7 7.87
63 INT96724 Gene_expression of Cyp3a11 10 0.77 4.82 7.76
64 INT13675 Gene_expression of Cyp2c22 23 0.39 4.52 7.71
65 INT17867 Positive_regulation of Cyp1a2 39 0.69 2.58 7.57
66 INT57922 Gene_expression of CYP2C9 65 0.78 22.24 7.53
67 INT22834 Negative_regulation of CYP21A2 28 0.58 23.07 7.13
68 INT116428 Gene_expression of Cybb 68 0.76 35.81 7.07
69 INT78404 Gene_expression of COX5A 24 0.75 9.73 7.07
70 INT63057 Regulation of CYP3A4 31 0.61 5.75 6.92
71 INT76025 Positive_regulation of Cyp3a11 20 0.69 5.88 6.91
72 INT18759 Positive_regulation of Gene_expression of CYP2E1 22 0.70 5.02 6.84
73 INT17145 Binding of Cyp2c22 19 0.42 1.39 6.8
74 INT140170 Binding of Nqo1 24 0.38 36.16 6.79
75 INT17143 Regulation of Cyp2c22 18 0.60 3.02 6.7
76 INT16720 Negative_regulation of Xdh 35 0.59 14 6.67
77 INT9818 Positive_regulation of Pdia4 12 0.34 0.67 6.65
78 INT2039 Regulation of CYP2B6 30 0.60 7.75 6.43
79 INT142082 Positive_regulation of IDO1 17 0.60 9.46 6.33
80 INT73382 Regulation of Nqo1 13 0.58 1.58 6.16
81 INT142904 Negative_regulation of Ptges2 14 0.47 9.49 6.15
82 INT43415 Gene_expression of CYP4A11 11 0.56 7.65 5.94
83 INT20331 Positive_regulation of CYP1A2 31 0.69 8.6 5.92
84 INT135760 Regulation of Gene_expression of Cyp19a1 2 0.62 1.15 5.81
85 INT28015 Regulation of Cyp3a23/3a1 19 0.40 6.32 5.79
86 INT68899 Binding of CYP1A2 19 0.48 2.33 5.73
87 INT84704 Positive_regulation of Nqo1 18 0.70 18.64 5.65
88 INT162328 Regulation of Ptges2 21 0.19 12.07 5.56
89 INT185 Regulation of Cyp1a1 18 0.54 2.71 5.56
90 INT12183 Negative_regulation of Cyp2d1 11 0.58 3.11 5.49
91 INT62579 Negative_regulation of Gene_expression of Cyp2e1 8 0.59 2.95 5.48
92 INT116434 Positive_regulation of Gene_expression of CYBB 27 0.62 16.24 5.42
93 INT18772 Positive_regulation of Gene_expression of CYP2B6 14 0.49 2.93 5.4
94 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37
95 INT23952 Gene_expression of Cyp2d4 18 0.78 4.76 5.31
96 INT53184 Negative_regulation of CYP27A1 46 0.57 16.04 5.28
97 INT65135 Binding of CYP2C19 17 0.48 1.82 5.2
98 INT230829 Localization of Cyp2d4 3 0.63 0.61 5.18
99 INT2435 Negative_regulation of Cyp1a1 15 0.58 3.32 5.16
100 INT19934 Negative_regulation of Ptgis 18 0.32 6.18 5.03
101 INT186 Positive_regulation of Cyp1a1 30 0.70 5 5.02
102 INT134297 Positive_regulation of Gene_expression of Ptges2 22 0.41 13.12 4.97
103 INT49292 Positive_regulation of Cyp1a2 17 0.69 6.16 4.96
104 INT131152 Gene_expression of Cr1l 17 0.75 10.83 4.88
105 INT191343 Gene_expression of IDO1 23 0.55 11.3 4.81
106 INT110549 Negative_regulation of CYP2C8 15 0.59 0.54 4.78
107 INT55419 Regulation of CYP1A2 19 0.62 5.3 4.75
108 INT62291 Gene_expression of PTGES2 14 0.68 8.34 4.75
109 INT100772 Negative_regulation of TXNRD1 10 0.41 3.47 4.74
110 INT95538 Localization of CYP2D6 21 0.81 5.69 4.73
111 INT61245 Positive_regulation of Cyp2b2 9 0.64 0.41 4.7
112 INT114718 Positive_regulation of Gene_expression of CYP3A4 17 0.49 4.69 4.69
113 INT65514 Gene_expression of Cyp1a2 25 0.77 6.12 4.6
114 INT65881 Gene_expression of CYP2C19 21 0.76 1.19 4.57
115 INT200218 Localization of SDHD 1 0.69 48.58 4.57
116 INT140199 Positive_regulation of Gene_expression of Cyp3a23/3a1 9 0.45 4.91 4.56
117 INT59041 Negative_regulation of CYP2E1 17 0.59 5.47 4.51
118 INT20121 Negative_regulation of CYBB 34 0.54 15.5 4.44
119 INT35765 Gene_expression of TXNRD1 47 0.56 9.16 4.43
120 INT52088 Binding of Cyp2e1 8 0.48 2.5 4.43
121 INT35599 Negative_regulation of Nqo1 25 0.54 4.6 4.42
122 INT45725 Binding of Pdia3 8 0.47 3.61 4.42
123 INT86516 Positive_regulation of Hmox2 6 0.69 3.22 4.39
124 INT60188 Positive_regulation of Cyp2d4 10 0.70 1.04 4.35
125 INT100262 Positive_regulation of Positive_regulation of Cyp2e1 7 0.50 2.39 4.31
126 INT35744 Binding of MAOB 13 0.46 7.52 4.26
127 INT138698 Gene_expression of Txn1 15 0.77 11.71 4.24
128 INT108823 Binding of COX5A 8 0.47 4.06 4.14
129 INT180338 Binding of Cyp2d4 12 0.47 6.87 4.09
130 INT93911 Regulation of COX5A 11 0.60 4.94 4.05
131 INT84703 Negative_regulation of Nqo1 8 0.38 7.1 4.05
132 INT138701 Positive_regulation of Gene_expression of Txn1 10 0.50 9.16 4.03
133 INT33951 Regulation of TXNRD1 18 0.51 6.97 4.02
134 INT158593 Negative_regulation of Negative_regulation of CYP3A4 5 0.43 1.16 4.01
135 INT83887 Gene_expression of HMOX2 10 0.77 7.99 3.85
136 INT22223 Positive_regulation of Xdh 18 0.67 5.87 3.84
137 INT66242 Gene_expression of Ptgis 15 0.64 6.73 3.84
138 INT20303 Regulation of Cyp2e1 11 0.61 2.46 3.84
139 INT6956 Gene_expression of PTGIS 29 0.76 12.1 3.8
140 INT134296 Positive_regulation of Ptges2 20 0.19 14.85 3.8
141 INT79096 Binding of Cyp2e1 12 0.48 4.41 3.8
142 INT26233 Binding of GSR 45 0.46 18.22 3.74
143 INT112 Gene_expression of Pdia3 11 0.74 0.18 3.74
144 INT99889 Transcription of SRD5A1 5 0.71 1.45 3.74
145 INT53395 Positive_regulation of Cyp2c6 6 0.70 0.07 3.73
146 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
147 INT80892 Negative_regulation of Hmox2 10 0.55 4.76 3.64
148 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61
149 INT9295 Regulation of MAOB 12 0.56 3.32 3.6
150 INT55516 Gene_expression of Cyp2d1 5 0.60 0.83 3.58
151 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56
152 INT134694 Binding of CYP27A1 10 0.47 5.61 3.56
153 INT69943 Regulation of Gene_expression of Nqo1 3 0.26 0.98 3.56
154 INT14110 Positive_regulation of Positive_regulation of Cyp2c22 6 0.67 1.45 3.45
155 INT180591 Protein_catabolism of CYP27A1 18 0.56 8.46 3.44
156 INT91070 Regulation of GSR 27 0.59 16.64 3.42
157 INT4545 Negative_regulation of Nox1 15 0.53 10.08 3.4
158 INT155983 Gene_expression of Cyp11a1 7 0.58 2.6 3.38
159 INT71199 Positive_regulation of Gene_expression of Cyp1a2 4 0.69 1.41 3.36
160 INT172852 Localization of Cyct 28 0.78 21.42 3.34
161 INT8764 Positive_regulation of Positive_regulation of Cyp3a23/3a1 5 0.45 1.62 3.33
162 INT71195 Transcription of Cyp1a2 6 0.53 2.41 3.24
163 INT69564 Binding of Cyp3a23/3a1 11 0.34 4.67 3.2
164 INT139355 Regulation of Gene_expression of Ptges2 11 0.17 6.37 3.19
165 INT18744 Localization of Nqo1 7 0.69 1.06 3.19
166 INT76024 Negative_regulation of Cyp3a11 7 0.53 2.96 3.16
167 INT53388 Negative_regulation of Cyp2c11 18 0.53 2.66 3.11
168 INT116376 Transcription of Cyp19a1 2 0.40 0.74 3.04
169 INT24309 Binding of Sdhb 2 0.36 0.98 3.03
170 INT162835 Positive_regulation of Cybb 38 0.68 16.09 3.02
171 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01
172 INT100785 Protein_catabolism of CYP3A4 7 1.00 0.76 3.01
173 INT133809 Negative_regulation of Gene_expression of CYP19A1 9 0.43 7.67 2.99
174 INT83351 Positive_regulation of Gene_expression of GSR 15 0.64 12.03 2.97
175 INT113277 Positive_regulation of Gene_expression of CYP19A1 13 0.69 10.23 2.97
176 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96
177 INT145710 Localization of CYP2C9 9 0.75 1.66 2.89
178 INT14902 Negative_regulation of XDH 38 0.55 24.19 2.86
179 INT28934 Negative_regulation of Gene_expression of Cyp2c22 9 0.12 2.15 2.86
180 INT22194 Gene_expression of Xdh 20 0.75 10.03 2.83
181 INT39908 Gene_expression of Cyp27b1 16 0.69 4.8 2.83
182 INT89229 Positive_regulation of Gene_expression of Nqo1 2 0.06 0.1 2.81
183 INT52084 Localization of Cyp2e1 6 0.71 1.99 2.79
184 INT22212 Gene_expression of CYP1A1 34 0.76 10.11 2.77
185 INT60339 Gene_expression of CYP21A2 8 0.66 4.04 2.77
186 INT90960 Positive_regulation of Gene_expression of CYP2D6 9 0.50 2.06 2.76
187 INT87822 Binding of Cyp1a2 8 0.47 0.84 2.72
188 INT155216 Negative_regulation of Gene_expression of CYP3A4 9 0.56 3.81 2.71
189 INT57957 Localization of TXNRD1 14 0.64 4.01 2.7
190 INT207366 Negative_regulation of Gene_expression of CYP27A1 11 0.44 4.82 2.67
191 INT172853 Positive_regulation of Localization of Cyct 14 0.67 10.48 2.65
192 INT126498 Positive_regulation of Negative_regulation of Cyp1a2 2 0.41 1.21 2.64
193 INT93207 Negative_regulation of Cyp4a3 11 0.36 4.32 2.63
194 INT86517 Positive_regulation of Gene_expression of Hmox2 1 0.69 0.14 2.63
195 INT91349 Negative_regulation of Binding of Pdia3 1 0.57 1.12 2.59
196 INT20304 Transcription of Cyp2e1 11 0.70 2.5 2.57
197 INT133747 Positive_regulation of COX5A 5 0.49 1.9 2.57
198 INT145126 Positive_regulation of GLRX 5 0.12 4.55 2.53
199 INT139354 Negative_regulation of Gene_expression of Ptges2 11 0.23 4.28 2.51
200 INT92545 Regulation of Hmox2 1 0.15 1.09 2.5
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