GO:0009083

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Name branched chain family amino acid catabolic process
Categary Process
Go Slim No
Go Link GO:0009083
Unique Molecular Interactions 47
Total Molecular Interactions 60
Total Single Events 343
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for branched chain family amino acid catabolic process. They are ordered first by their pain relevance and then by number of times they were reported for branched chain family amino acid catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT80053 Negative_regulation of Binding of ACAT1 and NA 1 0.01 0.25 0.45
2 INT80052 Binding of ACAT1 and NA 1 0.01 0.24 0.44
3 INT17059 Binding of DLD and Oxt 1 0.03 0.22 0.41
4 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27
5 INT323147 Binding of CA2 and DBT 1 0.01 0.17 0.26
6 INT341779 DBT Positive_regulation of PRKCA 1 0.02 0 0.22
7 INT341778 DBT Positive_regulation of MAP2K6 1 0.00 0 0.21
8 INT323174 DBT Positive_regulation of Phosphorylation of Akt1 1 0.01 0 0.21
9 INT328310 DBT Positive_regulation of Localization of GH1 1 0.00 0 0.19
10 INT175596 Binding of ACAT1 and HGF 1 0.01 1.58 0.18
11 INT316249 DBT Regulation of TRPM8 1 0.08 1.28 0.15
12 INT323149 Positive_regulation of DBT Regulation of CA2 1 0.01 0 0.13
13 INT323151 DBT Regulation of CA2 1 0.01 0 0.13
14 INT127156 HSD17B10 Regulation of Acaa2 1 0.02 0 0.12
15 INT270667 Binding of Bcat1 and Prh1 1 0.01 0.89 0.12
16 INT341775 DBT Regulation of Binding of ESR1 1 0.02 0.1 0.11
17 INT76965 Mpo Negative_regulation of DLD 1 0.26 0.91 0.07
18 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05
19 INT310321 DLD Negative_regulation of COQ10A 1 0.01 0.06 0.05
20 INT187672 Binding of DBT and SCN5A 1 0.00 0.2 0
21 INT187677 Negative_regulation of FSHR Positive_regulation of DBT 1 0.03 0 0
22 INT285996 Binding of ACAT1 and IL1RL1 1 0.00 0 0
23 INT187675 DBT Positive_regulation of Gene_expression of LEP 1 0.04 0.27 0
24 INT276607 Binding of DBT and PSMD1 1 0.00 0.08 0
25 INT276606 Binding of DBT and IL33 1 0.01 0 0
26 INT191166 Regulation of DBT Positive_regulation of PGR 1 0.01 0 0
27 INT187667 DBT Positive_regulation of Localization of LEP 1 0.05 0.55 0
28 INT299373 Binding of DBT and ENOPH1 1 0.00 0.24 0
29 INT191169 DBT Positive_regulation of PGR 1 0.02 0 0
30 INT191170 DBT Positive_regulation of Positive_regulation of PGR 1 0.02 0 0
31 INT321124 Binding of DBT and IgG 1 0.00 0.44 0
32 INT354106 Binding of BCAT1 and PTH 1 0.04 0 0
33 INT191168 DBT Negative_regulation of ESR1 1 0.02 0 0
34 INT327198 DBT Positive_regulation of Gene_expression of ESRRA 1 0.00 0.42 0
35 INT176919 Binding of DLD and Bpifa2 1 0.00 0.08 0
36 INT321105 Binding of DBT and F5 1 0.00 1.69 0
37 INT316250 Negative_regulation of DBT Negative_regulation of Gene_expression of TRPM8 1 0.11 1.06 0
38 INT187669 FSHR Positive_regulation of DBT 1 0.03 0 0
39 INT273772 BCKDHA Positive_regulation of Positive_regulation of NARFL 1 0.03 1.21 0
40 INT354105 BCAT1 Regulation of PTH 1 0.07 0.48 0
41 INT191172 DBT Positive_regulation of Regulation of ESR1 1 0.02 0 0
42 INT191167 DBT Positive_regulation of Localization of ESR1 1 0.03 0 0
43 INT191173 Regulation of DBT Negative_regulation of ESR1 1 0.01 0 0
44 INT321100 Binding of DBT and RNY4 1 0.01 0.44 0
45 INT185654 DBT Negative_regulation of AR 1 0.02 0.09 0
46 INT176920 DLD Positive_regulation of Binding of Bpifa2 1 0.00 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for branched chain family amino acid catabolic process. They are ordered first by their pain relevance and then by number of times they were reported in branched chain family amino acid catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT38556 Gene_expression of DBT 47 0.50 12.52 5.6
2 INT17056 Gene_expression of DLD 37 0.57 13.15 5.47
3 INT94095 Negative_regulation of BCAT1 9 0.49 0.97 4.91
4 INT12796 Binding of DLD 20 0.36 6.71 3.02
5 INT7142 Positive_regulation of DLD 22 0.60 7.69 2.76
6 INT53447 Negative_regulation of DLD 17 0.54 12.9 2.48
7 INT76633 Regulation of BCAT1 2 0.04 0.79 1.61
8 INT76596 Gene_expression of BCAT1 5 0.58 0.73 1.32
9 INT105425 Binding of BCAT1 5 0.42 0.78 1.17
10 INT69421 Positive_regulation of ACAT1 5 0.23 1.56 1.08
11 INT107653 Gene_expression of ACAT1 9 0.60 4.74 1.03
12 INT175280 Binding of DBT 19 0.08 6.37 0.98
13 INT38557 Positive_regulation of Gene_expression of DBT 8 0.37 2.05 0.92
14 INT61613 Regulation of DLD 6 0.34 2.96 0.92
15 INT94094 Localization of BCAT1 2 0.63 0 0.9
16 INT38558 Positive_regulation of DBT 9 0.31 1.59 0.86
17 INT187709 Regulation of Gene_expression of DBT 3 0.04 0.63 0.8
18 INT129900 Negative_regulation of Binding of BCAT1 1 0.38 0 0.78
19 INT48909 Localization of DLD 9 0.63 3.37 0.75
20 INT187712 Negative_regulation of DBT 11 0.19 2.99 0.65
21 INT55594 Negative_regulation of Positive_regulation of DLD 1 0.02 0.62 0.53
22 INT69420 Positive_regulation of Positive_regulation of ACAT1 1 0.23 0.17 0.45
23 INT187716 Positive_regulation of Positive_regulation of DBT 2 0.08 0 0.34
24 INT108298 Regulation of BCKDHA 3 0.22 1.17 0.33
25 INT175209 Regulation of DBT 9 0.12 2.03 0.2
26 INT108300 Positive_regulation of BCKDHA 3 0.39 1.74 0.18
27 INT128120 Transcription of DLD 1 0.67 0 0.18
28 INT43708 Negative_regulation of Binding of DLD 1 0.35 0.17 0.17
29 INT108299 Negative_regulation of BCKDHA 1 0.36 0.59 0.16
30 INT83129 Protein_catabolism of DLD 1 0.02 0 0.12
31 INT270632 Binding of Bcat1 1 0.34 0.88 0.12
32 INT242263 Regulation of ACAT1 4 0.09 0.66 0.1
33 INT127149 Gene_expression of HSD17B10 3 0.58 2.06 0.09
34 INT137756 Regulation of Negative_regulation of DLD 1 0.02 0.09 0.09
35 INT242264 Binding of ACAT1 3 0.12 1.05 0.06
36 INT244341 Regulation of Binding of DLD 1 0.30 0.19 0.06
37 INT242265 Negative_regulation of Gene_expression of ACAT1 3 0.14 0 0.04
38 INT127148 Negative_regulation of HSD17B10 1 0.04 0.19 0.04
39 INT196407 Binding of HSD17B10 2 0.21 0.58 0.03
40 INT187731 Negative_regulation of Gene_expression of DBT 1 0.09 0.3 0.03
41 INT39570 Localization of ACAT1 2 0.75 0.44 0
42 INT199987 Negative_regulation of Binding of DBT 2 0.04 0.07 0
43 INT276615 Negative_regulation of Localization of DBT 1 0.08 0.28 0
44 INT208223 Transcription of BCAT1 1 0.12 0.3 0
45 INT286001 Phosphorylation of ACAT1 1 0.09 0 0
46 INT286003 Negative_regulation of ACAT1 1 0.05 0 0
47 INT217416 Positive_regulation of Positive_regulation of DLD 1 0.42 0.19 0
48 INT354107 Positive_regulation of BCAT1 1 0.05 0.15 0
49 INT221520 Negative_regulation of Gene_expression of DLD 1 0.04 0.27 0
50 INT132990 Positive_regulation of Binding of BCKDHA 1 0.18 0.17 0
51 INT276614 Localization of DBT 1 0.16 0.53 0
52 INT312976 Protein_catabolism of ACAT1 1 0.02 0.46 0
53 INT285999 Transcription of ACAT1 1 0.08 0 0
54 INT132991 Binding of BCKDHA 1 0.16 0.17 0
55 INT286000 Positive_regulation of Phosphorylation of ACAT1 1 0.06 0 0
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