GO:0009403

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Name toxin biosynthetic process
Categary Process
Go Slim No
Go Link GO:0009403
Unique Molecular Interactions 33
Total Molecular Interactions 37
Total Single Events 457
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for toxin biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for toxin biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT90221 Binding of CYP2D6 and Cyp1a2 1 0.03 0.09 1.31
2 INT56273 RYBP Negative_regulation of Cyp1a2 1 0.01 0.17 0.9
3 INT56275 RYBP Positive_regulation of Negative_regulation of Cyp1a2 1 0.01 0.17 0.81
4 INT102630 Cyp3a62 Negative_regulation of Cyp1a2 1 0.40 0 0.81
5 INT56272 Cyp2e1 Positive_regulation of Cyp1a2 1 0.52 0.17 0.77
6 INT28184 Binding of CYP1A2 and CYP2D6 1 0.00 0 0.7
7 INT351276 CYP2D6 Regulation of CYP1A2 1 0.12 0 0.63
8 INT330984 Negative_regulation of CYP2D6 Positive_regulation of Localization of CYP1A2 1 0.46 0 0.62
9 INT102671 Cyp1a2 Regulation of RYBP 1 0.00 0 0.58
10 INT102666 Cyp2e1 Regulation of Cyp1a2 1 0.20 0 0.58
11 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
12 INT92803 Binding of CYP1A2 and VKORC1 1 0.31 0.12 0.48
13 INT92804 Positive_regulation of Binding of CYP1A2 and VKORC1 1 0.41 0.12 0.48
14 INT130678 CYP2C9 Regulation of Cyp1a2 1 0.06 0 0.26
15 INT262353 TRIP10 Negative_regulation of Cyp1a2 1 0.03 0.8 0.26
16 INT162501 NEUROD1 Regulation of CYP1A2 2 0.22 0.09 0.25
17 INT130663 Cyp1a2 Regulation of Binding of Ugt2b7 1 0.12 0 0.25
18 INT351318 Binding of CYP2C19 and Cyp1a2 1 0.01 0.28 0.22
19 INT264106 Cyp1a2 Regulation of CYP2D6 1 0.06 0 0.09
20 INT162507 Gtf3a Regulation of CYP1A2 1 0.00 0.09 0.09
21 INT264104 Cyp1a2 Regulation of CYP2C9 1 0.04 0 0.09
22 INT264102 Cyp1a2 Regulation of CYP3A4 1 0.03 0 0.09
23 INT168368 Binding of Cyp1a2 and Cyp2e1 1 0.37 0.08 0.07
24 INT22567 Cyp1a2 Positive_regulation of Tcf21 1 0.04 0 0.06
25 INT345925 IL6 Negative_regulation of Gene_expression of CYP1A2 1 0.13 0.18 0.06
26 INT264568 Binding of STS and CYP1A2 1 0.20 0.18 0.06
27 INT180372 CYP2A6 Regulation of Cyp1a2 1 0.03 2.02 0.05
28 INT285385 Ass1 Positive_regulation of Transcription of Cyp1a2 1 0.00 0.09 0.03
29 INT20322 Binding of CYP1A2 and CYP26A1 1 0.00 0 0
30 INT20326 Binding of CYP1A2 and CYP21A2 1 0.01 0 0
31 INT53286 Binding of CYP1A2 and OPN1LW 1 0.03 0 0
32 INT157283 CYP1A2 Positive_regulation of Gm7100 1 0.00 0 0
33 INT95055 Binding of CYP1A2 and TXNRD1 1 0.04 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for toxin biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in toxin biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT39914 Negative_regulation of Cyp1a2 44 0.58 10.04 22
2 INT50404 Negative_regulation of CYP1A2 49 0.59 8.61 17.35
3 INT71189 Gene_expression of Cyp1a2 24 0.78 11.39 11.12
4 INT22210 Gene_expression of CYP1A2 45 0.78 4.95 10.66
5 INT47860 Negative_regulation of Cyp1a2 20 0.57 6.06 10
6 INT17867 Positive_regulation of Cyp1a2 39 0.69 2.58 7.57
7 INT20331 Positive_regulation of CYP1A2 31 0.69 8.6 5.92
8 INT68899 Binding of CYP1A2 19 0.48 2.33 5.73
9 INT49292 Positive_regulation of Cyp1a2 17 0.69 6.16 4.96
10 INT55419 Regulation of CYP1A2 19 0.62 5.3 4.75
11 INT65514 Gene_expression of Cyp1a2 25 0.77 6.12 4.6
12 INT71199 Positive_regulation of Gene_expression of Cyp1a2 4 0.69 1.41 3.36
13 INT71195 Transcription of Cyp1a2 6 0.53 2.41 3.24
14 INT87822 Binding of Cyp1a2 8 0.47 0.84 2.72
15 INT126498 Positive_regulation of Negative_regulation of Cyp1a2 2 0.41 1.21 2.64
16 INT113081 Negative_regulation of Gene_expression of Cyp1a2 6 0.58 1.68 2.39
17 INT56337 Regulation of Cyp1a2 8 0.27 1.09 2.33
18 INT20332 Positive_regulation of Positive_regulation of CYP1A2 4 0.69 0.68 2.17
19 INT53390 Negative_regulation of Positive_regulation of Cyp1a2 2 0.35 0 2.03
20 INT65424 Positive_regulation of Gene_expression of CYP1A2 6 0.70 2.01 2.01
21 INT94396 Regulation of Cyp1a2 4 0.60 0.37 1.15
22 INT134955 Positive_regulation of Transcription of Cyp1a2 2 0.38 0.52 1.14
23 INT79635 Localization of Cyp1a2 2 0.74 0.26 0.97
24 INT130671 Regulation of Gene_expression of Cyp1a2 2 0.43 1.27 0.87
25 INT77927 Negative_regulation of Gene_expression of Cyp1a2 3 0.42 1.23 0.78
26 INT157282 Localization of CYP1A2 5 0.75 0.54 0.76
27 INT17868 Localization of Cyp1a2 3 0.75 0.05 0.75
28 INT94193 Transcription of Cyp1a2 4 0.65 1.29 0.74
29 INT17865 Regulation of Positive_regulation of Cyp1a2 2 0.45 0 0.74
30 INT331008 Positive_regulation of Localization of CYP1A2 1 0.42 0.06 0.7
31 INT351280 Negative_regulation of Negative_regulation of CYP1A2 1 0.27 0.53 0.69
32 INT71188 Binding of Cyp1a2 5 0.44 0.58 0.68
33 INT84396 Positive_regulation of Positive_regulation of Cyp1a2 2 0.24 0.22 0.34
34 INT273509 Positive_regulation of Gene_expression of Cyp1a2 2 0.14 1.2 0.33
35 INT144387 Positive_regulation of Negative_regulation of CYP1A2 2 0.39 0.64 0.28
36 INT17861 Positive_regulation of Localization of Cyp1a2 2 0.50 0.05 0.21
37 INT344068 Negative_regulation of Binding of CYP1A2 1 0.15 0.05 0.17
38 INT314338 Positive_regulation of Transcription of Cyp1a2 1 0.13 0.38 0.14
39 INT231567 Negative_regulation of Gene_expression of CYP1A2 2 0.36 0.06 0.13
40 INT162937 Regulation of Regulation of CYP1A2 1 0.45 0 0.12
41 INT162936 Regulation of Gene_expression of CYP1A2 1 0.45 0 0.12
42 INT137619 Protein_catabolism of Cyp1a2 1 0.33 0 0.11
43 INT135458 Negative_regulation of Negative_regulation of Cyp1a2 1 0.35 0.36 0.09
44 INT274055 Protein_catabolism of CYP1A2 1 0.47 0 0.06
45 INT73220 Regulation of Gene_expression of Cyp1a2 1 0.62 1.01 0.06
46 INT306772 Positive_regulation of Negative_regulation of Cyp1a2 1 0.08 0.06 0.04
47 INT303488 Negative_regulation of Positive_regulation of Cyp1a2 1 0.18 0.96 0
48 INT83244 Regulation of Positive_regulation of CYP1A2 1 0.43 1.18 0
49 INT158582 Negative_regulation of Positive_regulation of CYP1A2 1 0.41 0 0
50 INT167110 Regulation of Binding of CYP1A2 1 0.45 0 0
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