GO:0009404

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Name toxin metabolic process
Categary Process
Go Slim No
Go Link GO:0009404
Unique Molecular Interactions 33
Total Molecular Interactions 34
Total Single Events 506
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for toxin metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for toxin metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT90221 Binding of CYP2D6 and Cyp1a2 1 0.03 0.09 1.31
2 INT56273 RYBP Negative_regulation of Cyp1a2 1 0.01 0.17 0.9
3 INT56275 RYBP Positive_regulation of Negative_regulation of Cyp1a2 1 0.01 0.17 0.81
4 INT102630 Cyp3a62 Negative_regulation of Cyp1a2 1 0.40 0 0.81
5 INT56272 Cyp2e1 Positive_regulation of Cyp1a2 1 0.52 0.17 0.77
6 INT102671 Cyp1a2 Regulation of RYBP 1 0.00 0 0.58
7 INT102666 Cyp2e1 Regulation of Cyp1a2 1 0.20 0 0.58
8 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
9 INT147579 Binding of ATF4 and Cyp1a1 1 0.01 0.15 0.54
10 INT297689 Atn1 Regulation of Gene_expression of Il6 1 0.02 1.13 0.44
11 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28
12 INT130678 CYP2C9 Regulation of Cyp1a2 1 0.06 0 0.26
13 INT262353 TRIP10 Negative_regulation of Cyp1a2 1 0.03 0.8 0.26
14 INT130663 Cyp1a2 Regulation of Binding of Ugt2b7 1 0.12 0 0.25
15 INT57171 Binding of RYBP and Cyp1a1 1 0.01 0 0.23
16 INT351318 Binding of CYP2C19 and Cyp1a2 1 0.01 0.28 0.22
17 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
18 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
19 INT57170 Binding of Cyp1a1 and Cyp2b1 1 0.39 0 0.13
20 INT297695 Binding of Atn1 and Fut1 1 0.01 0.68 0.12
21 INT134201 Positive_regulation of Binding of AHR and Cyp1a1 1 0.21 0.07 0.1
22 INT134200 Binding of AHR and Cyp1a1 1 0.16 0.07 0.1
23 INT264106 Cyp1a2 Regulation of CYP2D6 1 0.06 0 0.09
24 INT264104 Cyp1a2 Regulation of CYP2C9 1 0.04 0 0.09
25 INT264102 Cyp1a2 Regulation of CYP3A4 1 0.03 0 0.09
26 INT168368 Binding of Cyp1a2 and Cyp2e1 1 0.37 0.08 0.07
27 INT22568 Cyp1a1 Positive_regulation of Tcf21 1 0.04 0 0.06
28 INT22567 Cyp1a2 Positive_regulation of Tcf21 1 0.04 0 0.06
29 INT180372 CYP2A6 Regulation of Cyp1a2 1 0.03 2.02 0.05
30 INT285385 Ass1 Positive_regulation of Transcription of Cyp1a2 1 0.00 0.09 0.03
31 INT275667 Binding of CYP1B1 and GLC3C 1 0.27 0.99 0
32 INT197295 Positive_regulation of Binding of Ahr and Cyp1a1 1 0.20 0 0
33 INT261981 EP400 Negative_regulation of CYP1B1 1 0.01 0.22 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for toxin metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in toxin metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT39914 Negative_regulation of Cyp1a2 44 0.58 10.04 22
2 INT71189 Gene_expression of Cyp1a2 24 0.78 11.39 11.12
3 INT47860 Negative_regulation of Cyp1a2 20 0.57 6.06 10
4 INT17867 Positive_regulation of Cyp1a2 39 0.69 2.58 7.57
5 INT185 Regulation of Cyp1a1 18 0.54 2.71 5.56
6 INT2435 Negative_regulation of Cyp1a1 15 0.58 3.32 5.16
7 INT186 Positive_regulation of Cyp1a1 30 0.70 5 5.02
8 INT49292 Positive_regulation of Cyp1a2 17 0.69 6.16 4.96
9 INT65514 Gene_expression of Cyp1a2 25 0.77 6.12 4.6
10 INT80681 Positive_regulation of Atn1 20 0.49 11.85 3.76
11 INT71199 Positive_regulation of Gene_expression of Cyp1a2 4 0.69 1.41 3.36
12 INT71195 Transcription of Cyp1a2 6 0.53 2.41 3.24
13 INT87822 Binding of Cyp1a2 8 0.47 0.84 2.72
14 INT126498 Positive_regulation of Negative_regulation of Cyp1a2 2 0.41 1.21 2.64
15 INT113081 Negative_regulation of Gene_expression of Cyp1a2 6 0.58 1.68 2.39
16 INT56337 Regulation of Cyp1a2 8 0.27 1.09 2.33
17 INT53390 Negative_regulation of Positive_regulation of Cyp1a2 2 0.35 0 2.03
18 INT297674 Gene_expression of Atn1 11 0.29 6.69 2
19 INT19409 Binding of Cyp1a1 12 0.48 2.58 1.97
20 INT17862 Localization of Cyp1a1 5 0.74 0.34 1.34
21 INT13674 Gene_expression of Cyp1a1 13 0.65 2.22 1.25
22 INT94396 Regulation of Cyp1a2 4 0.60 0.37 1.15
23 INT134955 Positive_regulation of Transcription of Cyp1a2 2 0.38 0.52 1.14
24 INT96873 Gene_expression of CYP1B1 28 0.78 11.81 1.09
25 INT79635 Localization of Cyp1a2 2 0.74 0.26 0.97
26 INT297663 Localization of Atn1 1 0.25 1.84 0.93
27 INT130671 Regulation of Gene_expression of Cyp1a2 2 0.43 1.27 0.87
28 INT96879 Positive_regulation of CYP1B1 14 0.70 5.73 0.78
29 INT77927 Negative_regulation of Gene_expression of Cyp1a2 3 0.42 1.23 0.78
30 INT17868 Localization of Cyp1a2 3 0.75 0.05 0.75
31 INT94193 Transcription of Cyp1a2 4 0.65 1.29 0.74
32 INT17865 Regulation of Positive_regulation of Cyp1a2 2 0.45 0 0.74
33 INT71188 Binding of Cyp1a2 5 0.44 0.58 0.68
34 INT80680 Negative_regulation of Atn1 3 0.42 1.5 0.64
35 INT297672 Positive_regulation of Localization of Atn1 1 0.17 0.94 0.55
36 INT115826 Transcription of Cyp1a1 4 0.52 1.15 0.53
37 INT2438 Regulation of Regulation of Cyp1a1 1 0.27 0 0.52
38 INT27414 Positive_regulation of Negative_regulation of Cyp1a1 1 0.49 0.44 0.41
39 INT115835 Negative_regulation of Positive_regulation of Cyp1a1 2 0.32 1.35 0.36
40 INT84396 Positive_regulation of Positive_regulation of Cyp1a2 2 0.24 0.22 0.34
41 INT273509 Positive_regulation of Gene_expression of Cyp1a2 2 0.14 1.2 0.33
42 INT13676 Negative_regulation of Gene_expression of Cyp1a1 1 0.33 0.1 0.29
43 INT297682 Binding of Atn1 4 0.16 1.58 0.28
44 INT99628 Positive_regulation of Gene_expression of Cyp1a1 4 0.25 1.3 0.27
45 INT52176 Positive_regulation of Binding of Cyp1a1 1 0.44 0 0.26
46 INT96888 Negative_regulation of Gene_expression of CYP1B1 5 0.43 1.13 0.23
47 INT96885 Localization of CYP1B1 4 0.80 2.11 0.23
48 INT115834 Positive_regulation of Transcription of Cyp1a1 2 0.38 0.64 0.23
49 INT96883 Positive_regulation of Gene_expression of CYP1B1 3 0.70 1.24 0.22
50 INT17861 Positive_regulation of Localization of Cyp1a2 2 0.50 0.05 0.21
51 INT96887 Regulation of Gene_expression of CYP1B1 2 0.45 0.9 0.2
52 INT134195 Regulation of Transcription of Cyp1a1 1 0.13 0.14 0.16
53 INT314338 Positive_regulation of Transcription of Cyp1a2 1 0.13 0.38 0.14
54 INT17866 Positive_regulation of Localization of Cyp1a1 1 0.49 0 0.12
55 INT137619 Protein_catabolism of Cyp1a2 1 0.33 0 0.11
56 INT17863 Regulation of Positive_regulation of Cyp1a1 1 0.27 0 0.09
57 INT135458 Negative_regulation of Negative_regulation of Cyp1a2 1 0.35 0.36 0.09
58 INT297667 Protein_catabolism of Atn1 1 0.19 0.36 0.08
59 INT297685 Positive_regulation of Protein_catabolism of Atn1 1 0.13 0.36 0.08
60 INT73220 Regulation of Gene_expression of Cyp1a2 1 0.62 1.01 0.06
61 INT306772 Positive_regulation of Negative_regulation of Cyp1a2 1 0.08 0.06 0.04
62 INT262005 Regulation of CYP1B1 4 0.62 4.52 0
63 INT262004 Negative_regulation of CYP1B1 4 0.59 3.24 0
64 INT262003 Binding of CYP1B1 3 0.48 3.34 0
65 INT303488 Negative_regulation of Positive_regulation of Cyp1a2 1 0.18 0.96 0
66 INT320463 Transcription of CYP1B1 1 0.68 0.14 0
67 INT321525 Transcription of Atn1 1 0.30 0 0
68 INT85223 Regulation of Localization of Cyp1a1 1 0.03 0.1 0
69 INT321520 Regulation of Atn1 1 0.20 0 0
70 INT197269 Regulation of Gene_expression of Cyp1a1 1 0.16 0 0
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