GO:0009408

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Name response to heat
Categary Process
Go Slim No
Go Link GO:0009408
Unique Molecular Interactions 3705
Total Molecular Interactions 5408
Total Single Events 62665
Pain Genes Associated 92

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to heat. They are ordered first by their pain relevance and then by number of times they were reported for response to heat. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36
3 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
4 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
5 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
6 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
7 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
8 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
9 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
10 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
11 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52
12 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
13 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
14 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
15 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
16 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
17 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
18 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
19 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
20 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
21 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
22 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
23 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
24 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
25 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
26 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
27 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76
28 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
29 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
30 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
31 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
32 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
33 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
34 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
35 INT108472 Binding of NOS1 and PNOC 1 0.32 0.64 3.27
36 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
37 INT354207 Igfbp7 Positive_regulation of Accn3 1 0.52 6.55 3.24
38 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
39 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
40 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
41 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
42 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
43 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
44 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
45 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
46 INT30424 Penk Regulation of Localization of Sst 1 0.20 0 3.1
47 INT158752 Binding of TRPV1 and Rvm 1 0.05 1.6 3.1
48 INT158751 Binding of TRPV1 and Pag1 1 0.03 1.59 3.08
49 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
50 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
51 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
52 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
53 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
54 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
55 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
56 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
57 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
58 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
59 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
60 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
61 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
62 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
63 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
64 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
65 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
66 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
67 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69
68 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67
69 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
70 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
71 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58
72 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
73 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
74 INT107812 Nppa Positive_regulation of Localization of Sst 1 0.48 0.54 2.51
75 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
76 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
77 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
78 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
79 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
80 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
81 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
82 INT107165 Binding of Gabrg1 and Trpv1 2 0.01 0.16 2.34
83 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
84 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
85 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
86 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28
87 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
88 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
89 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
90 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
91 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
92 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
93 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
94 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
95 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
96 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
97 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18
98 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
99 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
100 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
101 INT3576 Sst Negative_regulation of Localization of Gh1 6 0.23 0 2.13
102 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
103 INT18593 Binding of Sst and Fdft1 2 0.11 0.08 2.12
104 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
105 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
106 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
107 INT167530 Phax Regulation of Gene_expression of Trpv1 1 0.16 0.86 2.05
108 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
109 INT18355 Penk Positive_regulation of Localization of Sst 1 0.31 0 2.04
110 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
111 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
112 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
113 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
114 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
115 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
116 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
117 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
118 INT13430 Abat Positive_regulation of Localization of Sst 2 0.33 0 1.94
119 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
120 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
121 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
122 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92
123 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
124 INT161079 Mcs18 Negative_regulation of Trpv1 1 0.40 0.82 1.9
125 INT169570 Binding of ROS1 and TRPV1 3 0.33 3.07 1.89
126 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
127 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
128 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
129 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
130 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88
131 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
132 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
133 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
134 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
135 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
136 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
137 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
138 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
139 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84
140 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
141 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
142 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
143 INT149491 PNOC Negative_regulation of Gene_expression of CD14 1 0.40 0.37 1.76
144 INT13979 Gast Positive_regulation of Localization of Sst 3 0.69 0.05 1.75
145 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
146 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75
147 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
148 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
149 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
150 INT31534 Binding of Sst and Oprl1 2 0.16 0.53 1.74
151 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
152 INT182565 Ptger2 Regulation of Trpv1 1 0.25 1.34 1.73
153 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
154 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
155 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
156 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
157 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
158 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
159 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
160 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
161 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
162 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
163 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
164 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
165 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
166 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
167 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
168 INT354210 Binding of Igfbp7 and Accn3 1 0.27 3.91 1.64
169 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
170 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
171 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
172 INT147654 DYT10 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.93 1.62
173 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
174 INT18592 Sst Regulation of Localization of Acot1 2 0.22 0 1.61
175 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
176 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
177 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
178 INT276670 Binding of Trpv1 and Nkx1-1 1 0.07 0.68 1.6
179 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
180 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 1 0.27 0.56 1.58
181 INT107815 Gene_expression of Sst Positive_regulation of Localization of Nppa 1 0.52 0.27 1.57
182 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
183 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
184 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
185 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
186 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
187 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
188 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
189 INT7797 Akr1d1 Regulation of Sst 1 0.02 0 1.54
190 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
191 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
192 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
193 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
194 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
195 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
196 INT42000 Trpv1 Positive_regulation of Cck 1 0.04 0 1.49
197 INT41999 Trpv1 Positive_regulation of Vip 1 0.04 0 1.49
198 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
199 INT116094 Binding of TACR1 and TFF2 1 0.06 0 1.47
200 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to heat. They are ordered first by their pain relevance and then by number of times they were reported in response to heat. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59
4 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
5 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
6 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
7 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42
8 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42
9 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
10 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81
11 INT2649 Regulation of Calca 433 0.62 146.05 330.95
12 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05
13 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
14 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59
15 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
16 INT1005 Localization of Sst 385 0.81 26.31 244.56
17 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
18 INT626 Localization of CALCA 289 0.81 125.39 221.15
19 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
20 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
21 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
22 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
23 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
24 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
25 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
26 INT2541 Binding of Calca 200 0.48 67.14 134.62
27 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4
28 INT5008 Localization of Calca 204 0.81 80.35 125.16
29 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
30 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75
31 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
32 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85
33 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71
34 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37
35 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
36 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
37 INT12082 Localization of IL6 365 0.81 241.78 105.78
38 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76
39 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
40 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03
41 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
42 INT397 Localization of SST 232 0.81 58.05 101.19
43 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
44 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
45 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
46 INT1004 Regulation of Sst 140 0.62 18.52 94.84
47 INT38731 Localization of Trpv1 138 0.81 52.73 90.49
48 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32
49 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
50 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
51 INT4830 Binding of Trpv1 158 0.48 45.11 84.2
52 INT4631 Positive_regulation of Sst 127 0.70 17.37 83.29
53 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98
54 INT2155 Negative_regulation of Sst 111 0.59 16.58 77.74
55 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46
56 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7
57 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23
58 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
59 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
60 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
61 INT6849 Localization of IL1B 229 0.81 112.56 69.63
62 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15
63 INT19511 Localization of Il6 212 0.81 118.17 67.67
64 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
65 INT8347 Gene_expression of SST 181 0.78 104.59 65.45
66 INT7280 Positive_regulation of Localization of Sst 97 0.70 5.64 63.37
67 INT96622 Localization of Trpv1 110 0.81 59.82 63.25
68 INT10706 Regulation of Il6 150 0.62 93.23 62.34
69 INT6761 Binding of CALCA 100 0.48 26.71 62.05
70 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
71 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
72 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61
73 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87
74 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
75 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
76 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
77 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35
78 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
79 INT49436 Binding of TRPV1 145 0.48 38.35 55.08
80 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
81 INT37219 Gene_expression of TACR1 56 0.78 32.4 54.16
82 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
83 INT4891 Transcription of Calca 81 0.72 35.27 53.75
84 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
85 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
86 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
87 INT5118 Regulation of SST 97 0.62 34.35 51.74
88 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64
89 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
90 INT5098 Negative_regulation of Localization of Sst 70 0.58 3.56 51.17
91 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
92 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
93 INT9210 Regulation of IL6 166 0.62 125.61 49.95
94 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24
95 INT9383 Localization of TRPV1 98 0.81 33.23 46.24
96 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
97 INT98498 Binding of Trpv1 75 0.48 33.67 44.4
98 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
99 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
100 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
101 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
102 INT81251 Gene_expression of Trpv2 78 0.78 28.27 41.76
103 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
104 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
105 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
106 INT4925 Binding of Tacr1 57 0.48 17.39 38.38
107 INT65125 Gene_expression of Tacr1 81 0.77 23.9 38.35
108 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02
109 INT80075 Regulation of Gene_expression of Trpv1 55 0.62 32.42 36.88
110 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
111 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
112 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
113 INT6484 Binding of IL1B 122 0.47 75.84 35.07
114 INT7282 Regulation of Localization of Sst 58 0.62 1.92 34.83
115 INT76531 Transcription of Trpv1 62 0.72 23.69 34.77
116 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69
117 INT692 Negative_regulation of SST 72 0.59 28.68 34.52
118 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28
119 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
120 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
121 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
122 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13
123 INT65698 Localization of CCL2 118 0.81 77.54 32.69
124 INT99610 Localization of MMP9 126 0.79 48.46 32.67
125 INT691 Binding of SST 67 0.48 24.66 32.67
126 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
127 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
128 INT9347 Localization of Il1b 58 0.81 26.13 31.53
129 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
130 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
131 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
132 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72
133 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
134 INT7412 Positive_regulation of SST 71 0.70 24.44 29.48
135 INT86437 Binding of IL6 154 0.48 121.22 29.3
136 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
137 INT98522 Gene_expression of Accn3 68 0.78 26.95 28.6
138 INT116737 Localization of Mif 63 0.81 52.97 28.11
139 INT22499 Regulation of Calca 42 0.62 17.32 28.02
140 INT82882 Localization of Ccl2 61 0.80 41.96 28
141 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19
142 INT7281 Binding of Sst 42 0.48 5.48 26.57
143 INT5966 Localization of Il1a 50 0.78 22.91 26.54
144 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
145 INT95481 Regulation of Gene_expression of TRPV1 48 0.62 29.3 26.28
146 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
147 INT112036 Phosphorylation of Trpv1 51 0.82 18.59 25.6
148 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
149 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
150 INT103320 Positive_regulation of Positive_regulation of Trpv1 44 0.70 27.73 25.28
151 INT92105 Transcription of Trpv1 47 0.71 27.47 25.01
152 INT48766 Regulation of NOS1 73 0.61 37.01 24.59
153 INT9377 Positive_regulation of Positive_regulation of TRPV1 43 0.70 15.81 24.47
154 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
155 INT49172 Regulation of Nos1 43 0.52 27.53 23.66
156 INT100124 Gene_expression of Accn3 38 0.78 30.02 23.63
157 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54
158 INT66026 Gene_expression of Cxcl1 74 0.78 31.87 23.37
159 INT125190 Regulation of Gene_expression of Trpv1 38 0.62 32.57 23.2
160 INT89056 Phosphorylation of Trpv1 46 0.82 13.52 22.16
161 INT693 Negative_regulation of Localization of SST 46 0.59 8.57 21.75
162 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72
163 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
164 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
165 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25
166 INT614 Gene_expression of Cxcl2 29 0.76 25.53 20.8
167 INT51474 Binding of Il6 55 0.48 44.99 20.52
168 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
169 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
170 INT41494 Negative_regulation of Gene_expression of Tacr1 25 0.58 11.73 19.91
171 INT96511 Negative_regulation of Positive_regulation of Trpv1 35 0.59 10.95 19.79
172 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
173 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
174 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
175 INT77902 Negative_regulation of Positive_regulation of TRPV1 30 0.59 9.36 19.2
176 INT91916 Gene_expression of P2rx3 51 0.78 21.2 19.05
177 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
178 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
179 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
180 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
181 INT18457 Transcription of Sst 25 0.69 4.28 18.25
182 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24
183 INT187513 Positive_regulation of Pla2g4a 5 0.62 34.09 18.22
184 INT90937 Negative_regulation of Gene_expression of Trpv1 34 0.59 22.74 18.12
185 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
186 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
187 INT61626 Transcription of IL6 73 0.72 42.04 17.86
188 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85
189 INT7414 Regulation of Localization of SST 31 0.60 4.85 17.46
190 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
191 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
192 INT101501 Phosphorylation of TRPV1 31 0.82 9.26 17.27
193 INT78233 Positive_regulation of P2rx3 36 0.56 21.49 17.25
194 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24
195 INT195831 Phosphorylation of Pla2g4a 15 0.74 34.43 17.14
196 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
197 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86
198 INT15202 Regulation of Tacr1 26 0.60 9.65 16.48
199 INT51576 Positive_regulation of Cxcl1 42 0.69 20.12 16.41
200 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
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