GO:0009409

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Name response to cold
Categary Process
Go Slim No
Go Link GO:0009409
Unique Molecular Interactions 2190
Total Molecular Interactions 3287
Total Single Events 35337
Pain Genes Associated 49

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to cold. They are ordered first by their pain relevance and then by number of times they were reported for response to cold. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
2 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87
3 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44
4 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
5 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
6 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39
7 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29
8 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
9 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
10 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
11 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
12 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
13 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
14 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
15 INT26677 Penk Regulation of Localization of Trh 5 0.50 0 3.05
16 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
17 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
18 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
19 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
20 INT137230 Trh Regulation of Gene_expression of Oprd1 1 0.01 1.62 2.75
21 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
22 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
23 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
24 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
25 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69
26 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
27 INT318998 IFNA1 Positive_regulation of Localization of CXCL10 1 0.15 2.09 2.39
28 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
29 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
30 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
31 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
32 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
33 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
34 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
35 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
36 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
37 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
38 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
39 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
40 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
41 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
42 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
43 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
44 INT283050 Binding of Gad2 and Trpm8 1 0.23 2.02 1.93
45 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
46 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
47 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
48 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
49 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
50 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
51 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
52 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
53 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
54 INT26676 Pomc Regulation of Localization of Trh 3 0.14 0 1.73
55 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
56 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
57 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
58 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
59 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
60 INT32839 Binding of Trh and Penk 2 0.42 0 1.63
61 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
62 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
63 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54
64 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
65 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
66 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
67 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
68 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
69 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
70 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
71 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
72 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
73 INT154685 Syt17 Positive_regulation of Trpa1 1 0.32 0.71 1.4
74 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
75 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
76 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
77 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
78 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
79 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
80 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35
81 INT33988 TRH Regulation of Localization of IGKV1D-39 1 0.12 0.47 1.35
82 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
83 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
84 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
85 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
86 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
87 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
88 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3
89 INT201942 DPP4 Negative_regulation of CXCL10 1 0.33 0.9 1.3
90 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29
91 INT162482 Binding of Agt and Vta1 1 0.23 0 1.27
92 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
93 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
94 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
95 INT69562 Positive_regulation of AP2M1 Positive_regulation of Regulation of Adrb3 1 0.01 0.19 1.24
96 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
97 INT71443 CSAD Positive_regulation of Gene_expression of Fos 1 0.58 0.81 1.23
98 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
99 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
100 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22
101 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
102 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
103 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
104 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
105 INT109380 Binding of Adarb1 and Fos 1 0.02 0.38 1.19
106 INT73075 Adarb1 Regulation of Fos 1 0.01 0.07 1.18
107 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16
108 INT105240 POMC Positive_regulation of Gene_expression of CXCL10 1 0.07 1.18 1.16
109 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
110 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
111 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12
112 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
113 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
114 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
115 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12
116 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
117 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
118 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
119 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
120 INT143941 Il1f5 Negative_regulation of Gene_expression of Fos 1 0.00 1.03 1.11
121 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
122 INT102421 POMC Regulation of Gene_expression of Fos 1 0.12 0.34 1.11
123 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
124 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
125 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
126 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
127 INT25036 TRH Regulation of Prl 4 0.27 1.75 1.09
128 INT7927 Penk Regulation of Trh 2 0.26 0.66 1.09
129 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
130 INT17414 TRH Positive_regulation of Prl 4 0.47 0 1.07
131 INT132701 Adarb1 Negative_regulation of Gene_expression of Fos 1 0.01 0.73 1.07
132 INT100564 CRX Positive_regulation of Fos 1 0.04 0.89 1.06
133 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
134 INT57509 Trh Negative_regulation of Adarb1 1 0.02 0.22 1.05
135 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
136 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
137 INT214875 Ap3d1 Negative_regulation of Gene_expression of Fos 1 0.00 0.39 1.04
138 INT146518 Tmem132a Positive_regulation of Gene_expression of Fos 1 0.68 0.06 1.04
139 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
140 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
141 INT203178 IL18 Positive_regulation of Gene_expression of Lts1 1 0.01 1.98 1.02
142 INT134384 Trpa1 Negative_regulation of Gene_expression of Trpm8 1 0.47 1.21 1.02
143 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
144 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
145 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
146 INT143177 Apcs Negative_regulation of Gene_expression of Fos 1 0.02 0.36 1.01
147 INT25155 TRH Positive_regulation of PRL 2 0.50 0.4 1
148 INT11251 Negative_regulation of Cck Positive_regulation of Fos 2 0.48 0 1
149 INT166625 Acer3 Positive_regulation of Trpa1 1 0.01 1.91 1
150 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
151 INT71319 Binding of Penk and Fos 3 0.40 0.15 0.99
152 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
153 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
154 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 0.05 0 0.99
155 INT94206 SP5 Regulation of Gene_expression of FOS 1 0.22 0.7 0.98
156 INT307100 Trpv1 Regulation of Binding of Trpa1 1 0.31 1.81 0.97
157 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
158 INT307103 Trpa1 Regulation of Binding of Trpv1 1 0.31 1.81 0.97
159 INT281375 Il1r1 Negative_regulation of Gene_expression of Fos 1 0.47 0.61 0.97
160 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
161 INT281380 Fos Negative_regulation of Gene_expression of FSCN1 1 0.07 0.4 0.96
162 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
163 INT155044 Negative_regulation of Ceacam3 Negative_regulation of Gene_expression of Fos 1 0.61 0 0.95
164 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
165 INT155043 Vta1 Regulation of Gene_expression of Fos 1 0.08 0 0.95
166 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
167 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
168 INT149389 Olfr1241 Positive_regulation of Trpa1 1 0.02 0.31 0.94
169 INT80601 Akr1d1 Regulation of Positive_regulation of Fos 1 0.06 0 0.94
170 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94
171 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
172 INT48148 Fos Positive_regulation of Gene_expression of Pdyn 1 0.21 0 0.94
173 INT186568 Hpcl1 Regulation of Gene_expression of Fos 1 0.22 0.07 0.94
174 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
175 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
176 INT281377 FSCN1 Positive_regulation of Gene_expression of Fos 1 0.08 0.49 0.93
177 INT89514 Pnoc Regulation of Gene_expression of Fos 1 0.47 0.98 0.93
178 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
179 INT143578 Olr404 Negative_regulation of Positive_regulation of Fos 1 0.01 0.39 0.93
180 INT221916 RPS3AP18 Negative_regulation of Positive_regulation of Trpa1 1 0.00 0.75 0.93
181 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
182 INT86350 Negative_regulation of Adarb1 Negative_regulation of Positive_regulation of Fos 1 0.04 0.8 0.92
183 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
184 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92
185 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
186 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
187 INT32840 Regulation of Binding of Trh and Penk 1 0.26 0 0.91
188 INT66536 Il1a Regulation of Gene_expression of Fos 1 0.59 0 0.91
189 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91
190 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
191 INT166221 Negative_regulation of Gls Negative_regulation of Gene_expression of Fos 1 0.50 0.37 0.9
192 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
193 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
194 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
195 INT164677 Ngf Positive_regulation of Gene_expression of Fos 1 0.52 0.08 0.89
196 INT149391 Trpa1 Positive_regulation of Positive_regulation of Olfr1241 1 0.03 0.26 0.88
197 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
198 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
199 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
200 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to cold. They are ordered first by their pain relevance and then by number of times they were reported in response to cold. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
3 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
4 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
5 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
6 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
7 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
8 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
9 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
10 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
11 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
12 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
13 INT12082 Localization of IL6 365 0.81 241.78 105.78
14 INT5587 Regulation of Fos 191 0.62 40.81 99.7
15 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
16 INT339 Regulation of Trh 156 0.62 39.27 83.55
17 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
18 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
19 INT403 Localization of Trh 241 0.81 28.55 81.45
20 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65
21 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9
22 INT1376 Binding of Trh 121 0.48 20 69.86
23 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83
24 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
25 INT19511 Localization of Il6 212 0.81 118.17 67.67
26 INT10706 Regulation of Il6 150 0.62 93.23 62.34
27 INT109431 Gene_expression of Trpa1 123 0.78 51.84 59.98
28 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
29 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
30 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74
31 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
32 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
33 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
34 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
35 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
36 INT9210 Regulation of IL6 166 0.62 125.61 49.95
37 INT2323 Gene_expression of Trh 146 0.78 29.92 49.5
38 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24
39 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14
40 INT121416 Gene_expression of Trpm8 101 0.78 52.7 47.85
41 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
42 INT989 Negative_regulation of Trh 90 0.59 15.45 43.63
43 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
44 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
45 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
46 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
47 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
48 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
49 INT6053 Transcription of Fos 107 0.72 20.97 31.88
50 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
51 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
52 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
53 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
54 INT117632 Gene_expression of Trpm8 99 0.78 29.41 30.9
55 INT6058 Localization of Fos 73 0.81 16.7 30.84
56 INT1158 Regulation of Agt 106 0.61 29.4 30.29
57 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
58 INT86437 Binding of IL6 154 0.48 121.22 29.3
59 INT149387 Negative_regulation of Trpa1 55 0.59 21.91 28.31
60 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9
61 INT127499 Positive_regulation of TRPA1 72 0.70 21.7 26.86
62 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
63 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95
64 INT117600 Positive_regulation of Trpm8 65 0.70 31.96 24.46
65 INT61665 Phosphorylation of Trh 53 0.79 2.26 23.9
66 INT127500 Gene_expression of TRPA1 79 0.78 24.58 23.3
67 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23
68 INT101592 Gene_expression of TRPM8 82 0.78 70.61 22.89
69 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
70 INT1327 Regulation of Localization of Trh 45 0.62 6.05 22.09
71 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05
72 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
73 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
74 INT5586 Binding of Fos 47 0.48 12.7 21.33
75 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
76 INT51474 Binding of Il6 55 0.48 44.99 20.52
77 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
78 INT91916 Gene_expression of P2rx3 51 0.78 21.2 19.05
79 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
80 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42
81 INT61626 Transcription of IL6 73 0.72 42.04 17.86
82 INT14419 Negative_regulation of Localization of Trh 40 0.59 2.04 17.42
83 INT78233 Positive_regulation of P2rx3 36 0.56 21.49 17.25
84 INT111416 Positive_regulation of Trpm8 65 0.70 14.62 17.13
85 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
86 INT134596 Regulation of Trpa1 32 0.62 18.78 17.02
87 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
88 INT13209 Regulation of Binding of Trh 19 0.62 2.84 16.26
89 INT2066 Localization of Agt 56 0.80 9.95 16.25
90 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
91 INT69652 Regulation of P2rx3 26 0.61 17.17 15.4
92 INT72188 Gene_expression of Cxcl10 22 0.65 12.93 15.35
93 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
94 INT170 Negative_regulation of Adrb1 52 0.55 13.46 14.78
95 INT663 Negative_regulation of Adrb3 55 0.59 15.95 14.68
96 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41
97 INT110 Regulation of Adrb3 33 0.60 8.09 13.84
98 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
99 INT92237 Positive_regulation of Gene_expression of CXCL10 43 0.70 43.67 13.65
100 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
101 INT233113 Regulation of Trpm8 24 0.61 18.08 13.17
102 INT3962 Regulation of AGT 50 0.62 20.96 13.01
103 INT15246 Regulation of FOS 32 0.60 15.34 12.94
104 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
105 INT4199 Binding of Agt 76 0.48 21.06 12.66
106 INT18539 Gene_expression of Pnmt 33 0.78 3.08 12.47
107 INT120432 Regulation of Trpa1 22 0.61 9.65 12.36
108 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
109 INT120828 Localization of CXCL10 29 0.68 18.01 12.17
110 INT83894 Positive_regulation of TRPM8 37 0.70 18.28 11.7
111 INT50933 Transcription of Il6 38 0.72 24.31 11.58
112 INT398 Localization of AGT 45 0.78 16.97 11.54
113 INT6051 Positive_regulation of Transcription of Fos 27 0.69 6.3 11.48
114 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
115 INT23825 Negative_regulation of Binding of Trh 17 0.59 1.62 11.24
116 INT987 Localization of TRH 37 0.78 10.53 11.1
117 INT10009 Positive_regulation of TRH 31 0.67 8.94 11.03
118 INT8065 Binding of AGT 54 0.48 20.54 10.85
119 INT143767 Negative_regulation of Trpm8 26 0.58 12.34 10.83
120 INT78579 Negative_regulation of P2rx3 23 0.59 10.13 10.78
121 INT52657 Phosphorylation of Fos 20 0.80 6.36 10.64
122 INT3637 Positive_regulation of Localization of Trh 33 0.70 2.13 10.55
123 INT143964 Positive_regulation of Phosphorylation of Trh 10 0.20 0.1 10.54
124 INT8188 Positive_regulation of Adrb3 27 0.68 7.32 10.44
125 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
126 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08
127 INT17592 Positive_regulation of Regulation of Fos 21 0.67 3.54 10.07
128 INT59 Regulation of Adrb1 25 0.42 8.32 9.78
129 INT134597 Binding of Trpa1 21 0.48 9.41 9.74
130 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53
131 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
132 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14
133 INT3922 Negative_regulation of Pnmt 29 0.59 3.18 8.96
134 INT67612 Binding of PPARG 38 0.48 22.67 8.94
135 INT30247 Regulation of Adrb1 18 0.44 4.45 8.93
136 INT78578 Localization of P2rx3 21 0.78 9.55 8.86
137 INT146346 Negative_regulation of Gene_expression of Trpa1 15 0.59 11.76 8.83
138 INT29411 Positive_regulation of ADRB2 13 0.65 5.42 8.78
139 INT146241 Positive_regulation of Gene_expression of Trpa1 23 0.69 8.07 8.74
140 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73
141 INT892 Regulation of TRH 23 0.60 8.46 8.54
142 INT96 Binding of Adrb1 18 0.48 2.8 8.52
143 INT17333 Positive_regulation of Positive_regulation of FOS 17 0.67 6.06 8.4
144 INT134381 Regulation of Trpm8 25 0.54 8.31 8.25
145 INT15459 Gene_expression of TRH 17 0.78 4.89 8.17
146 INT130502 Negative_regulation of Trpa1 17 0.59 5.75 8.06
147 INT26115 Gene_expression of Adrb1 14 0.64 5.13 7.78
148 INT47848 Negative_regulation of Positive_regulation of FOS 14 0.57 3.78 7.63
149 INT9932 Positive_regulation of Positive_regulation of Trh 13 0.50 1.8 7.63
150 INT23992 Positive_regulation of Adrb1 25 0.56 4.01 7.62
151 INT298 Negative_regulation of ADRB3 23 0.59 6.82 7.56
152 INT94127 Positive_regulation of Il18 14 0.69 14 7.47
153 INT7883 Binding of ADRB2 18 0.47 5.49 7.37
154 INT102080 Positive_regulation of P2rx3 20 0.67 6.91 7.3
155 INT134379 Binding of Trpa1 13 0.48 7.16 7.27
156 INT60196 Binding of FOS 33 0.47 13.11 6.95
157 INT131745 Positive_regulation of Gene_expression of Trpa1 13 0.69 8.07 6.95
158 INT23132 Positive_regulation of Pnmt 17 0.67 2.02 6.84
159 INT78232 Binding of P2rx3 25 0.41 6.26 6.78
160 INT126484 Localization of Trpa1 15 0.80 4.08 6.64
161 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
162 INT87939 Gene_expression of P2RX3 23 0.75 6.15 6.62
163 INT91721 Binding of IL18 21 0.48 21.17 6.56
164 INT131744 Transcription of Trpa1 9 0.68 7.67 6.47
165 INT5847 Transcription of FOS 31 0.69 11.11 6.41
166 INT50328 Positive_regulation of Vgf 8 0.70 13.98 6.37
167 INT7923 Transcription of Trh 14 0.72 4.44 6.32
168 INT139580 Negative_regulation of Trpm8 19 0.58 3.8 6.26
169 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
170 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13
171 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12
172 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
173 INT169687 Regulation of Gene_expression of Trpa1 10 0.60 7.02 5.94
174 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
175 INT100078 Positive_regulation of Positive_regulation of PPARG 11 0.70 3.6 5.86
176 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84
177 INT95475 Positive_regulation of P2RX3 13 0.67 6.28 5.82
178 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
179 INT34440 Negative_regulation of Positive_regulation of Trh 12 0.59 0 5.7
180 INT1243 Regulation of ADRB2 16 0.54 1.84 5.66
181 INT15542 Negative_regulation of CASP8 20 0.41 17.3 5.63
182 INT113420 Positive_regulation of Gene_expression of IL18 22 0.69 19.96 5.53
183 INT146347 Negative_regulation of Gene_expression of Trpm8 9 0.55 6.96 5.42
184 INT159442 Positive_regulation of Gene_expression of Trpm8 10 0.70 5.86 5.34
185 INT64716 Regulation of Positive_regulation of Il6 7 0.54 2.83 5.34
186 INT147869 Positive_regulation of Gene_expression of TRPA1 5 0.70 5.33 5.21
187 INT10078 Positive_regulation of Gene_expression of Trh 17 0.50 4.23 5.19
188 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
189 INT159443 Regulation of Gene_expression of Trpm8 9 0.57 6.63 5.12
190 INT13885 Positive_regulation of Adrb2 9 0.49 1.11 5.12
191 INT92234 Regulation of CXCL10 15 0.42 8.37 5.09
192 INT14455 Transcription of Pnmt 17 0.72 2.13 4.95
193 INT92236 Regulation of Gene_expression of CXCL10 6 0.42 7.12 4.92
194 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
195 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
196 INT147870 Binding of TRPA1 11 0.48 3.12 4.77
197 INT4577 Negative_regulation of Thra 24 0.56 3.75 4.73
198 INT12380 Localization of Pnmt 10 0.80 0.07 4.7
199 INT54911 Localization of FOS 20 0.78 3.27 4.56
200 INT91917 Negative_regulation of P2rx3 11 0.59 6.56 4.51
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