GO:0009411

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Name response to UV
Categary Process
Go Slim No
Go Link GO:0009411
Unique Molecular Interactions 874
Total Molecular Interactions 1101
Total Single Events 10422
Pain Genes Associated 32

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to UV. They are ordered first by their pain relevance and then by number of times they were reported for response to UV. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
2 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
3 INT139723 PROC Positive_regulation of MAPK8 1 0.01 2.98 2.33
4 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
5 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
6 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
7 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
8 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
9 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
10 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
11 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
12 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
13 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
14 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
15 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
16 INT134679 FSCN1 Positive_regulation of MAPK8 1 0.01 0.56 1.39
17 INT148778 Binding of Usf1 and Rtn1 1 0.40 0.85 1.3
18 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
19 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
20 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
21 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
22 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
23 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
24 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
25 INT62019 CSF2 Regulation of ELANE 1 0.03 0.47 1.21
26 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
27 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
28 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
29 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
30 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
31 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
32 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
33 INT167429 Negative_regulation of Mapk8 Negative_regulation of RYBP 1 0.01 1.11 1.09
34 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
35 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
36 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
37 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
38 INT223875 Negative_regulation of Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.31 0 1.07
39 INT119887 Binding of Atf4 and Usf1 1 0.21 0.15 1.05
40 INT119888 Binding of Creb1 and Usf1 1 0.18 0.15 1.05
41 INT312097 ELANE Regulation of ALOX5 1 0.08 1.75 1.05
42 INT145906 Elane Regulation of Transcription of Oprm1 1 0.10 0.14 1.04
43 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
44 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
45 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
46 INT62017 ELANE Positive_regulation of Localization of ACOT1 1 0.05 0.35 0.98
47 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
48 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95
49 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
50 INT13193 FPR1 Positive_regulation of ELANE 3 0.44 1.22 0.92
51 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
52 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
53 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
54 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
55 INT307045 Tmie Negative_regulation of Positive_regulation of Casp3 1 0.01 0.29 0.85
56 INT32441 POMC Positive_regulation of ELANE 1 0.13 0.09 0.83
57 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
58 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
59 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
60 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
61 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79
62 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
63 INT152234 Mapk8 Positive_regulation of Localization of Nfkb1 1 0.33 0.26 0.78
64 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
65 INT307044 Tmie Regulation of Casp3 1 0.01 0 0.75
66 INT98179 Aap Positive_regulation of Mapk8 1 0.01 0.75 0.74
67 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
68 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
69 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74
70 INT312101 ELANE Regulation of ALOX5AP 1 0.21 1.11 0.73
71 INT114860 Negative_regulation of Insrr Positive_regulation of Casp3 1 0.02 0.71 0.73
72 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
73 INT223873 Mapk8 Regulation of Positive_regulation of Ltp 1 0.24 0 0.71
74 INT223869 Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.20 0 0.68
75 INT293010 ELANE Regulation of Localization of LTF 1 0.00 0.54 0.67
76 INT151559 Atp2a1 Negative_regulation of Positive_regulation of CASP3 1 0.06 0.68 0.66
77 INT110458 Binding of Atf2 and Mapk8 1 0.35 0 0.66
78 INT330046 Mapk8 Negative_regulation of Prkcg 1 0.13 0.4 0.66
79 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
80 INT312105 ELANE Positive_regulation of Localization of PTGER2 4 0.03 1.3 0.64
81 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
82 INT158685 ROS1 Regulation of Positive_regulation of MAPK8 1 0.21 0.39 0.64
83 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
84 INT100030 TNF Positive_regulation of Mapk8 1 0.12 1.57 0.63
85 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
86 INT169295 PTPLA Positive_regulation of MAPK8 1 0.10 0.15 0.63
87 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62
88 INT11558 POMC Positive_regulation of CASP3 1 0.05 0 0.62
89 INT148780 Binding of Usf2 and Usf1 1 0.40 0.41 0.62
90 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
91 INT32782 Binding of Vip and Elane 1 0.17 0 0.61
92 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
93 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
94 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61
95 INT128812 Mapk8 Negative_regulation of Gene_expression of Nos2 1 0.19 0.37 0.61
96 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
97 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61
98 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
99 INT114505 Negative_regulation of Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
100 INT114506 Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
101 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
102 INT163376 RYBP Positive_regulation of Gene_expression of Casp3 2 0.01 0.57 0.59
103 INT148779 Usf1 Negative_regulation of Calca 1 0.44 0.4 0.59
104 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58
105 INT278689 TNF Positive_regulation of MAPK8 1 0.04 0.79 0.56
106 INT112399 Olr897-ps Regulation of Gene_expression of Casp3 1 0.03 0 0.54
107 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
108 INT200913 Dio1 Positive_regulation of Mapk8 1 0.00 0 0.53
109 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
110 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52
111 INT57248 ELANE Regulation of Gene_expression of CGA 1 0.05 0 0.52
112 INT74517 Binding of Casp3 and Cnrip1 1 0.31 0 0.51
113 INT234609 Binding of CASP3 and IMMT 1 0.00 0.5 0.5
114 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49
115 INT312118 ELANE Regulation of PTGES 1 0.22 0.92 0.49
116 INT228448 PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
117 INT228447 Negative_regulation of PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
118 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
119 INT65006 DAK Negative_regulation of ELANE 1 0.05 0.35 0.47
120 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
121 INT312112 ELANE Regulation of Transcription of ALOX5 1 0.09 0.82 0.47
122 INT307048 Cnr1 Positive_regulation of Casp3 1 0.08 0 0.47
123 INT254225 Mapk14 Positive_regulation of Mapk8 1 0.02 0.87 0.46
124 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46
125 INT319554 Sgk1 Regulation of Cdkn1a 1 0.26 0.09 0.45
126 INT221026 ELANE Positive_regulation of Gene_expression of CCL18 1 0.01 0.57 0.45
127 INT56631 Negative_regulation of FPR1 Positive_regulation of ELANE 1 0.38 0.54 0.44
128 INT353331 Elane Positive_regulation of F2r 1 0.08 0.78 0.44
129 INT278950 MAPK8 Negative_regulation of Localization of EPHB2 1 0.25 0.47 0.43
130 INT264476 Il1a Positive_regulation of Gene_expression of Mapk8 1 0.04 0 0.43
131 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
132 INT116931 OPRK1 Regulation of MAPK8 1 0.31 0.07 0.43
133 INT264475 Il1a Positive_regulation of Mapk8 1 0.04 0 0.43
134 INT293007 IRF6 Positive_regulation of ELANE 1 0.00 0 0.42
135 INT116938 Positive_regulation of GLI2 Positive_regulation of MAPK8 1 0.10 0.07 0.41
136 INT57236 Casp3 Positive_regulation of Prl 1 0.09 0 0.41
137 INT319312 Socs4 Positive_regulation of Mapk8 1 0.05 0.68 0.41
138 INT221027 ELANE Positive_regulation of IL8 2 0.14 1.3 0.4
139 INT57235 Casp3 Positive_regulation of Localization of Prl 1 0.15 0 0.4
140 INT312123 ELANE Positive_regulation of ALOX5 1 0.09 0.74 0.4
141 INT312122 ELANE Positive_regulation of Protein_catabolism of COL2A1 1 0.05 0.65 0.39
142 INT312086 ELANE Positive_regulation of MMP13 1 0.13 0.64 0.39
143 INT179938 Negative_regulation of Mapk8 Negative_regulation of TNF 1 0.02 1.09 0.37
144 INT187233 Positive_regulation of Mapk8 Positive_regulation of Jun 1 0.12 0.92 0.37
145 INT264480 Il1a Positive_regulation of Phosphorylation of Mapk8 1 0.04 0 0.37
146 INT52960 Casp3 Negative_regulation of Positive_regulation of Ltp 1 0.02 0 0.37
147 INT145908 Pdyn Regulation of Positive_regulation of Casp3 1 0.14 0.94 0.37
148 INT309120 Edc4 Negative_regulation of Positive_regulation of Mapk8 1 0.01 1.03 0.36
149 INT308653 Proc Regulation of Gene_expression of Mapk8 1 0.00 1.48 0.36
150 INT330106 Racgap1 Positive_regulation of Positive_regulation of Mapk8 1 0.01 1.32 0.35
151 INT312750 Elane Positive_regulation of Positive_regulation of Ltp 1 0.01 0.38 0.34
152 INT228446 PMAIP1 Regulation of Transcription of Mtpn 1 0.00 0 0.34
153 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
154 INT119262 PPM1E Negative_regulation of Positive_regulation of CDKN1A 1 0.01 0.96 0.33
155 INT312119 ELANE Positive_regulation of Gene_expression of PTGES 1 0.18 0.74 0.33
156 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
157 INT312099 ELANE Positive_regulation of Gene_expression of PTGER2 1 0.02 0.64 0.32
158 INT348016 Binding of Mapk8 and Mapk8ip3 1 0.04 2.09 0.32
159 INT346286 ELANE Positive_regulation of MAPK1 1 0.06 0.65 0.32
160 INT346281 Binding of ELANE and MAPK1 1 0.04 0.65 0.32
161 INT110461 Binding of Mapk8 and Gtf3a 1 0.03 0 0.32
162 INT312085 ELANE Regulation of Regulation of ALOX5 1 0.09 0.64 0.32
163 INT286708 Negative_regulation of Mapk1 Negative_regulation of Casp3 1 0.12 0 0.31
164 INT282421 Mapk8 Negative_regulation of Ins1 1 0.06 2.48 0.31
165 INT253153 TNF Positive_regulation of Mapk8 1 0.18 0.61 0.31
166 INT167983 Mapk8 Negative_regulation of gr 1 0.02 0.5 0.31
167 INT253155 TNF Positive_regulation of Positive_regulation of Mapk8 1 0.19 0.62 0.31
168 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
169 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
170 INT112795 Positive_regulation of CASP1 Positive_regulation of MAPK8 1 0.02 0.16 0.3
171 INT112803 CASP1 Positive_regulation of MAPK8 1 0.02 0.16 0.29
172 INT190826 ELANE Positive_regulation of Localization of MUC1 1 0.07 0 0.29
173 INT116358 Binding of C3 and ELANE 1 0.12 0 0.29
174 INT159964 Tnf Positive_regulation of Phosphorylation of Mapk8 1 0.11 0.94 0.29
175 INT226505 Il1rl1 Positive_regulation of Mapk8 1 0.04 0.4 0.29
176 INT226509 Il1rl1 Positive_regulation of Gene_expression of Mapk8 1 0.05 0.4 0.29
177 INT116356 Positive_regulation of Binding of C3 and ELANE 1 0.16 0 0.29
178 INT166162 Ccr9 Negative_regulation of Positive_regulation of Casp3 1 0.18 1.49 0.28
179 INT309122 Edc4 Positive_regulation of Phosphorylation of Mapk8 1 0.02 0.73 0.28
180 INT237679 IRF6 Positive_regulation of MAPK8 1 0.00 0.56 0.28
181 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
182 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
183 INT172977 Cdkn1a Negative_regulation of Positive_regulation of Inca1 1 0.00 1.39 0.27
184 INT132368 Mapk8 Positive_regulation of Nfkb1 1 0.17 0.11 0.27
185 INT132369 Mapk8 Positive_regulation of Positive_regulation of Nfkb1 1 0.18 0.12 0.27
186 INT132366 Lgals1 Positive_regulation of Mapk8 1 0.38 0.13 0.27
187 INT132370 Mapk8 Positive_regulation of Ephb1 1 0.15 0.12 0.27
188 INT179928 Binding of Ephb1 and Mapk8 1 0.11 0.91 0.26
189 INT237380 Binding of Cdkn2d and Il12b 1 0.01 0.45 0.26
190 INT171907 MAPK8 Positive_regulation of Gene_expression of MAPK14 1 0.06 0.77 0.26
191 INT148629 Binding of Cat and Casp3 1 0.08 0.09 0.26
192 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
193 INT171913 MAPK8 Positive_regulation of MAPK9 1 0.07 0.78 0.26
194 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
195 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
196 INT312115 ELANE Positive_regulation of Transcription of PTGES 1 0.25 0.53 0.25
197 INT121249 Binding of ANXA5 and CASP3 1 0.36 0.67 0.25
198 INT149713 Binding of Casp3 and Fas 1 0.40 1.09 0.25
199 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
200 INT312569 IL6 Positive_regulation of Localization of ELANE 1 0.11 1.05 0.24

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to UV. They are ordered first by their pain relevance and then by number of times they were reported in response to UV. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
2 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
3 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
4 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
5 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
6 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
7 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
8 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38
9 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75
10 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
11 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
12 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
13 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
14 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
15 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94
16 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
17 INT2609 Localization of ELANE 111 0.81 50.22 26.63
18 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
19 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
20 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09
21 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79
22 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25
23 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
24 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
25 INT116950 Negative_regulation of MAPK8 103 0.57 44.48 17.53
26 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24
27 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86
28 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
29 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
30 INT109929 Phosphorylation of MAPK8 102 0.81 39.98 16.54
31 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2
32 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
33 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
34 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
35 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88
36 INT80685 Gene_expression of MAPK8 90 0.72 51.91 13.36
37 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
38 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65
39 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44
40 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
41 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
42 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
43 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
44 INT145695 Regulation of Mapk8 26 0.62 14.67 9.83
45 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
46 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
47 INT111998 Positive_regulation of Positive_regulation of Mapk8 23 0.69 9.33 8.97
48 INT104481 Regulation of Mapk8 21 0.50 13.87 8.41
49 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
50 INT88919 Positive_regulation of Casp9 39 0.70 28.64 8.18
51 INT96912 Positive_regulation of Phosphorylation of Mapk8 29 0.69 18.33 8.14
52 INT98178 Localization of Casp3 32 0.65 21.01 7.77
53 INT80686 Positive_regulation of Positive_regulation of MAPK8 42 0.68 26.95 7.63
54 INT99071 Positive_regulation of Gene_expression of Mapk8 16 0.55 9.87 7.58
55 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
56 INT2605 Regulation of ELANE 39 0.61 18.22 7.11
57 INT102814 Negative_regulation of CASP3 46 0.43 28.54 6.94
58 INT102749 Positive_regulation of Positive_regulation of CASP3 32 0.67 26.07 6.93
59 INT108585 Positive_regulation of Gene_expression of CASP3 35 0.70 28.37 6.45
60 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
61 INT57232 Binding of Casp3 22 0.36 9.42 6.2
62 INT116420 Localization of Elane 16 0.14 7.8 6
63 INT134544 Negative_regulation of Positive_regulation of CASP3 23 0.57 18.48 5.95
64 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
65 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69
66 INT128922 Negative_regulation of Gene_expression of Mapk8 6 0.34 3.93 5.36
67 INT95120 Positive_regulation of CASP9 76 0.67 67.55 5.33
68 INT109928 Negative_regulation of Positive_regulation of MAPK8 19 0.42 10.42 5.23
69 INT10100 Binding of ELANE 22 0.47 15.32 5.19
70 INT135291 Positive_regulation of Positive_regulation of Mapk8 24 0.64 19.37 5.16
71 INT131717 Positive_regulation of Gene_expression of Mapk8 18 0.55 14.25 5.02
72 INT17582 Negative_regulation of Localization of ELANE 17 0.53 6.11 4.89
73 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
74 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
75 INT75523 Regulation of MAPK8 21 0.33 11.18 4.28
76 INT109935 Positive_regulation of Phosphorylation of MAPK8 35 0.68 13.13 4.18
77 INT110181 Negative_regulation of Phosphorylation of MAPK8 20 0.57 9.43 4.06
78 INT132103 Positive_regulation of Gene_expression of MAPK8 26 0.46 16.54 3.94
79 INT88805 Protein_catabolism of CASP3 24 0.86 18.38 3.7
80 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
81 INT97126 Regulation of CASP3 9 0.40 8.15 3.6
82 INT179656 Gene_expression of Elane 12 0.32 9.44 3.53
83 INT21569 Binding of Mapk8 8 0.48 5.55 3.44
84 INT22891 Positive_regulation of Localization of ELANE 16 0.69 11.52 3.42
85 INT42581 Regulation of Gene_expression of ELANE 11 0.38 9.25 3.38
86 INT22823 Positive_regulation of Positive_regulation of ELANE 12 0.45 6.89 3.35
87 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
88 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26
89 INT163529 Negative_regulation of Positive_regulation of Mapk8 14 0.43 8.37 3.2
90 INT25674 Positive_regulation of Gene_expression of ELANE 16 0.60 7.46 3.12
91 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
92 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
93 INT116143 Positive_regulation of Casp9 32 0.67 30.34 3.04
94 INT28731 Negative_regulation of Elane 14 0.14 8.97 3.01
95 INT110755 Negative_regulation of Positive_regulation of Mapk8 15 0.46 9.91 2.98
96 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
97 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74
98 INT95735 Regulation of Phosphorylation of Mapk8 7 0.50 1.88 2.69
99 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
100 INT95739 Negative_regulation of Phosphorylation of Mapk8 11 0.42 6.77 2.61
101 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
102 INT141183 Gene_expression of Casp9 9 0.75 11.96 2.46
103 INT131112 Phosphorylation of Casp3 7 0.63 4.1 2.46
104 INT31118 Localization of Casp3 17 0.73 11.55 2.3
105 INT129280 Gene_expression of Casp9 9 0.68 5.48 2.25
106 INT108589 Negative_regulation of Gene_expression of CASP3 13 0.57 10.52 2.14
107 INT109908 Localization of MAPK8 10 0.73 3.86 2.14
108 INT124583 Negative_regulation of Elane 8 0.29 5.26 2.14
109 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12
110 INT42583 Protein_catabolism of ELANE 8 0.89 4.33 2.11
111 INT156270 Regulation of Positive_regulation of Mapk8 3 0.41 2.31 2.08
112 INT151467 Localization of CASP9 9 0.73 7.62 2.04
113 INT152696 Negative_regulation of Negative_regulation of Mapk8 1 0.32 0.35 2
114 INT69702 Positive_regulation of PMAIP1 7 0.35 8.81 1.98
115 INT109313 Binding of Mapk8 6 0.48 1.78 1.98
116 INT96916 Negative_regulation of Phosphorylation of Mapk8 16 0.52 9.68 1.97
117 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
118 INT51502 Positive_regulation of Elane 5 0.22 2.3 1.94
119 INT36245 Negative_regulation of Gene_expression of ELANE 11 0.40 5.32 1.88
120 INT83358 Positive_regulation of Elane 8 0.21 8.14 1.83
121 INT164864 Positive_regulation of Negative_regulation of Mapk8 1 0.31 1.33 1.82
122 INT122488 Protein_catabolism of CASP9 8 0.46 8.64 1.8
123 INT122487 Positive_regulation of Positive_regulation of CASP9 16 0.67 17.88 1.79
124 INT299365 Transcription of Mapk8 9 0.72 5.91 1.75
125 INT121964 Positive_regulation of Positive_regulation of Casp9 8 0.32 5.52 1.73
126 INT88916 Negative_regulation of Casp9 5 0.33 3.01 1.67
127 INT97062 Binding of PML 10 0.41 11.63 1.65
128 INT102532 Protein_catabolism of Casp3 24 0.64 16.78 1.64
129 INT104331 Negative_regulation of Gene_expression of CDKN1A 24 0.57 13.68 1.63
130 INT168714 Negative_regulation of Binding of Mapk8 1 0.36 0.18 1.62
131 INT88920 Negative_regulation of Positive_regulation of Casp9 7 0.59 5.27 1.57
132 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
133 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
134 INT106749 Negative_regulation of Negative_regulation of Casp3 6 0.34 5.12 1.48
135 INT140843 Regulation of Phosphorylation of Casp3 1 0.25 0.37 1.44
136 INT172953 Binding of Trp53 33 0.37 20.76 1.41
137 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
138 INT145221 Binding of Tp53 10 0.37 8.59 1.37
139 INT171690 Transcription of Casp3 8 0.55 2.62 1.36
140 INT97943 Positive_regulation of Protein_catabolism of Casp3 7 0.28 7.4 1.35
141 INT119880 Binding of Usf1 5 0.20 2.55 1.28
142 INT125079 Negative_regulation of Gene_expression of MAPK8 9 0.39 4.87 1.25
143 INT154048 Negative_regulation of Gene_expression of Mapk8 5 0.43 4.43 1.22
144 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21
145 INT5652 Negative_regulation of Positive_regulation of ELANE 7 0.37 2.46 1.21
146 INT174156 Localization of Trp53 16 0.72 13.52 1.18
147 INT141184 Negative_regulation of Casp9 5 0.42 5.48 1.15
148 INT141190 Negative_regulation of Transcription of Casp9 1 0.57 1.42 1.15
149 INT234422 Gene_expression of PML 14 0.75 15.93 1.14
150 INT141178 Transcription of Casp9 1 0.69 1.42 1.14
151 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
152 INT122485 Negative_regulation of CASP9 18 0.46 15.78 1.12
153 INT148765 Gene_expression of Usf1 1 0.77 0.72 1.12
154 INT17805 Regulation of Localization of ELANE 7 0.59 1.88 1.08
155 INT102845 Localization of CASP3 7 0.81 2.81 1.06
156 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
157 INT141187 Positive_regulation of Gene_expression of Casp9 3 0.49 4.2 1
158 INT31117 Binding of Casp3 14 0.23 5.27 0.93
159 INT86907 Negative_regulation of MSH6 8 0.33 6.76 0.93
160 INT169235 Negative_regulation of USF1 4 0.37 2.69 0.91
161 INT32443 Negative_regulation of Binding of ELANE 2 0.11 0.54 0.89
162 INT203132 Negative_regulation of Gene_expression of Elane 1 0.20 1.5 0.86
163 INT200900 Localization of Mapk8 9 0.40 5.76 0.84
164 INT131105 Positive_regulation of Negative_regulation of Casp3 3 0.29 3.15 0.84
165 INT116419 Negative_regulation of Localization of Elane 2 0.01 0.58 0.82
166 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
167 INT146521 Negative_regulation of Positive_regulation of CDKN1A 6 0.42 3.29 0.79
168 INT142422 Regulation of Positive_regulation of ELANE 1 0.02 0.65 0.78
169 INT182293 Binding of MAPK8 11 0.34 4.6 0.77
170 INT165104 Negative_regulation of Negative_regulation of Mapk8 5 0.43 4.21 0.77
171 INT181667 Regulation of Regulation of Casp3 1 0.22 1.7 0.77
172 INT165105 Localization of Mapk8 7 0.69 4.45 0.76
173 INT46295 Regulation of Negative_regulation of ELANE 4 0.39 2.34 0.76
174 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
175 INT137503 Positive_regulation of Positive_regulation of Casp9 6 0.67 4.66 0.74
176 INT164489 Regulation of Gene_expression of Mapk8 2 0.44 0.65 0.74
177 INT184694 Gene_expression of Usf1 10 0.55 4.27 0.72
178 INT237709 Negative_regulation of Negative_regulation of MAPK8 6 0.25 2.09 0.72
179 INT262726 Localization of PML 6 0.57 7.13 0.72
180 INT129490 Negative_regulation of Protein_catabolism of Casp3 4 0.22 3.91 0.71
181 INT25663 Localization of PMAIP1 3 0.38 2.47 0.71
182 INT224579 Gene_expression of Cdkn2d 6 0.41 4.23 0.68
183 INT153008 Gene_expression of Elane 3 0.66 1.66 0.67
184 INT351454 Regulation of Transcription of Casp3 1 0.02 0.51 0.67
185 INT285006 Positive_regulation of Casp7 4 0.25 4.11 0.66
186 INT25664 Negative_regulation of Localization of PMAIP1 1 0.09 0.09 0.66
187 INT131976 Positive_regulation of Protein_catabolism of CASP3 4 0.49 3.76 0.64
188 INT130385 Gene_expression of ERCC6 7 0.77 8.36 0.63
189 INT126732 Regulation of Cdkn1a 6 0.39 2.13 0.63
190 INT177936 Positive_regulation of Negative_regulation of MAPK8 3 0.50 2.1 0.63
191 INT197832 Localization of MEN1 1 0.80 11.01 0.63
192 INT164585 Regulation of PMAIP1 2 0.20 2.07 0.61
193 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
194 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
195 INT158689 Positive_regulation of Regulation of MAPK8 1 0.46 0.41 0.6
196 INT51501 Positive_regulation of Positive_regulation of Elane 1 0.09 0.5 0.59
197 INT242061 Positive_regulation of Negative_regulation of Casp3 3 0.09 1.7 0.58
198 INT148766 Positive_regulation of Gene_expression of Usf1 1 0.69 0.39 0.57
199 INT181673 Negative_regulation of Transcription of Casp3 3 0.34 0.61 0.55
200 INT109926 Positive_regulation of Localization of MAPK8 4 0.49 0.87 0.52
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