GO:0009414

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Name response to water deprivation
Categary Process
Go Slim No
Go Link GO:0009414
Unique Molecular Interactions 73
Total Molecular Interactions 96
Total Single Events 1986
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to water deprivation. They are ordered first by their pain relevance and then by number of times they were reported for response to water deprivation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
2 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61
3 INT40887 Penk Regulation of Th 1 0.04 0 1.53
4 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 0.13 0.15 1.36
5 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
6 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
7 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
8 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
9 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
10 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
11 INT106069 TH Positive_regulation of Th 1 0.07 0.16 1.14
12 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1
13 INT31547 Binding of Th and Vip 1 0.31 0 1.08
14 INT41175 Adra2a Regulation of Th 1 0.59 0 1.04
15 INT31548 Binding of Th and Dbh 1 0.35 0 0.98
16 INT63940 Negative_regulation of Vta1 Positive_regulation of Th 1 0.13 0 0.81
17 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
18 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
19 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
20 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
21 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
22 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
23 INT7958 LOC686180 Positive_regulation of Gene_expression of Th 1 0.02 0 0.64
24 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56
25 INT77508 ST13 Negative_regulation of Gene_expression of CD9 1 0.09 0.5 0.54
26 INT7957 Calca Positive_regulation of Gene_expression of Th 1 0.39 0 0.47
27 INT121837 Sct Positive_regulation of Th 1 0.23 0.06 0.43
28 INT139487 Oprm1 Positive_regulation of Th 1 0.26 0.1 0.42
29 INT7625 Man2a2 Regulation of Th 1 0.01 0.07 0.4
30 INT31794 Hps6 Positive_regulation of Th 1 0.03 0 0.38
31 INT84600 Binding of Avp and Aqp2 1 0.17 0 0.35
32 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
33 INT173476 Th Regulation of Gene_expression of Bcar1 1 0.10 0 0.34
34 INT34855 Negative_regulation of Maoa Negative_regulation of Th 1 0.17 0 0.34
35 INT173478 Th Regulation of Localization of Ins1 1 0.13 0 0.34
36 INT153019 nct Positive_regulation of Transcription of Th 1 0.19 0.61 0.32
37 INT153020 nct Positive_regulation of Gene_expression of Th 1 0.19 0.61 0.32
38 INT55404 Binding of ENG and Th 1 0.02 0 0.3
39 INT314484 TH Positive_regulation of RLS 1 0.01 1.66 0.29
40 INT78484 Binding of DBH and TH 1 0.09 0 0.28
41 INT293118 Avp Regulation of Aqp2 1 0.04 0.7 0.27
42 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
43 INT329432 Binding of CCR6 and TH 1 0.00 0.47 0.23
44 INT329431 Binding of CCL20 and TH 1 0.00 0.47 0.23
45 INT61987 Th Regulation of Penk 1 0.46 0 0.2
46 INT88450 Uncx Regulation of Gene_expression of Th 1 0.06 0 0.17
47 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14
48 INT51367 Slc14a2 Positive_regulation of Localization of Slc4a4 1 0.03 0.1 0.14
49 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14
50 INT261456 Sftpd Positive_regulation of Gene_expression of Th 1 0.10 0.77 0.13
51 INT10730 CD9 Regulation of CD4 1 0.42 1.3 0.12
52 INT10732 NEUROD1 Regulation of CD9 1 0.49 1.29 0.12
53 INT92297 Slc14a2 Regulation of Sct 1 0.05 0 0.1
54 INT83827 Negative_regulation of Binding of Adrb1 and Pnmt 1 0.02 0 0.1
55 INT83828 Binding of Adrb1 and Pnmt 1 0.01 0 0.1
56 INT66171 Negative_regulation of Adra2a Negative_regulation of Positive_regulation of Pnmt 1 0.38 0 0.08
57 INT66166 Negative_regulation of Binding of Pnmt and Adra2a 1 0.38 0 0.07
58 INT66167 Negative_regulation of Pnmt Negative_regulation of Adra2a 1 0.38 0 0.07
59 INT66172 Binding of Pnmt and Adra2a 1 0.33 0 0.07
60 INT293122 Avp Regulation of Gene_expression of Aqp2 1 0.04 0.81 0.05
61 INT189546 Binding of CD9 and FN1 1 0.01 0.6 0
62 INT292968 Fto Regulation of Gene_expression of Th 1 0.30 1.11 0
63 INT292970 Fto Regulation of Th 1 0.18 0.48 0
64 INT127058 Vta1 Negative_regulation of Positive_regulation of Th 1 0.33 0 0
65 INT245820 Binding of Sp1 and Tfap2a 1 0.03 0.64 0
66 INT49943 Binding of Th and Pdx1 1 0.02 0.17 0
67 INT245828 Binding of VEGFA and Tfap2a 1 0.01 0.64 0
68 INT163744 Binding of Th and Gfra4 1 0.09 0 0
69 INT256993 Binding of Cd9 and Cd81 1 0.18 0.22 0
70 INT293114 Fig4 Regulation of Gene_expression of Aqp2 1 0.08 1.53 0
71 INT256983 Binding of Cd9 and Ezr 1 0.06 0.12 0
72 INT51366 Slc14a2 Regulation of Localization of Slc4a4 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to water deprivation. They are ordered first by their pain relevance and then by number of times they were reported in response to water deprivation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
2 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
3 INT7327 Regulation of Th 164 0.62 29.67 110.14
4 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
5 INT350 Localization of Th 79 0.80 10.26 41.17
6 INT7326 Transcription of Th 83 0.72 13.5 35.33
7 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
8 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
9 INT4781 Gene_expression of TH 68 0.73 26.92 24.01
10 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78
11 INT13643 Phosphorylation of Th 20 0.82 1.9 20.97
12 INT13716 Positive_regulation of TH 33 0.68 19.11 16
13 INT31368 Positive_regulation of Positive_regulation of Th 19 0.51 2.2 12.68
14 INT18539 Gene_expression of Pnmt 33 0.78 3.08 12.47
15 INT141 Binding of Th 21 0.48 3.53 11.04
16 INT48496 Regulation of Transcription of Th 16 0.54 2.29 10.02
17 INT3922 Negative_regulation of Pnmt 29 0.59 3.18 8.96
18 INT26643 Negative_regulation of Positive_regulation of Th 12 0.59 1.26 7.74
19 INT7624 Positive_regulation of Regulation of Th 7 0.50 2.41 7
20 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88
21 INT23132 Positive_regulation of Pnmt 17 0.67 2.02 6.84
22 INT3506 Localization of TH 12 0.81 0.78 6.66
23 INT7569 Positive_regulation of Transcription of Th 19 0.70 2.6 6.17
24 INT30317 Regulation of TH 14 0.43 7.27 5.38
25 INT7623 Regulation of Regulation of Th 11 0.44 1.31 5.16
26 INT14455 Transcription of Pnmt 17 0.72 2.13 4.95
27 INT12380 Localization of Pnmt 10 0.80 0.07 4.7
28 INT40620 Regulation of Positive_regulation of Th 9 0.45 2.45 4.69
29 INT30165 Positive_regulation of Phosphorylation of Th 8 0.56 0.75 4.22
30 INT18538 Regulation of Pnmt 11 0.60 1.03 3.84
31 INT77823 Negative_regulation of Negative_regulation of Th 9 0.59 1.56 3.79
32 INT52227 Gene_expression of CD9 11 0.75 6.23 3.71
33 INT30166 Regulation of Phosphorylation of Th 4 0.50 0.52 3.33
34 INT4782 Positive_regulation of Gene_expression of TH 12 0.47 7.36 2.95
35 INT106066 Negative_regulation of Positive_regulation of TH 1 0.18 0.22 2.6
36 INT106068 Positive_regulation of Positive_regulation of TH 1 0.21 0.22 2.59
37 INT4704 Positive_regulation of Negative_regulation of Th 4 0.50 0.06 2.56
38 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54
39 INT52228 Negative_regulation of Gene_expression of CD9 3 0.57 2.45 2.54
40 INT13644 Negative_regulation of Phosphorylation of Th 2 0.43 0.06 2.51
41 INT57088 Negative_regulation of Slc14a2 9 0.19 2.27 2.39
42 INT15210 Negative_regulation of Transcription of Th 9 0.59 0.47 2.37
43 INT15209 Negative_regulation of Regulation of Th 6 0.51 1.64 2.16
44 INT28468 Positive_regulation of Transcription of Pnmt 4 0.67 0.63 2.04
45 INT1834 Positive_regulation of Binding of Th 1 0.46 0 1.91
46 INT314510 Protein_catabolism of TH 1 0.10 3.28 1.86
47 INT229906 Gene_expression of Cd9 1 0.51 1.29 1.84
48 INT3505 Binding of TH 5 0.39 2.6 1.8
49 INT84595 Negative_regulation of Aqp2 11 0.58 4.88 1.78
50 INT145545 Transcription of TH 3 0.67 1.48 1.64
51 INT28478 Regulation of Gene_expression of Pnmt 5 0.44 0 1.41
52 INT70790 Positive_regulation of Slc14a2 4 0.18 1.36 1.16
53 INT26760 Negative_regulation of Localization of Th 2 0.40 0.09 1.14
54 INT79557 Localization of Aqp2 5 0.73 2 1.13
55 INT89670 Negative_regulation of Binding of Th 2 0.43 0.28 1.12
56 INT28469 Positive_regulation of Gene_expression of Pnmt 4 0.49 0.73 1.11
57 INT84597 Transcription of Aqp2 3 0.55 2.11 0.98
58 INT208792 Negative_regulation of Gene_expression of TH 6 0.35 1.11 0.94
59 INT208789 Negative_regulation of Localization of TH 2 0.25 0 0.89
60 INT84598 Regulation of Aqp2 13 0.45 4.28 0.86
61 INT53309 Regulation of Localization of Th 1 0.39 0 0.84
62 INT108348 Positive_regulation of Aqp2 10 0.68 4.94 0.82
63 INT47518 Negative_regulation of Positive_regulation of Pnmt 2 0.42 0.32 0.8
64 INT202521 Negative_regulation of Negative_regulation of Slc14a2 1 0.05 0.2 0.75
65 INT149238 Positive_regulation of Gene_expression of Aqp2 5 0.66 3.07 0.73
66 INT48489 Regulation of Slc14a2 3 0.04 0.46 0.71
67 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
68 INT12379 Regulation of Localization of Pnmt 1 0.17 0 0.69
69 INT25134 Positive_regulation of CD9 3 0.49 3.38 0.66
70 INT115200 Binding of Slc14a2 2 0.07 1.16 0.66
71 INT122934 Negative_regulation of Regulation of TH 1 0.03 0.56 0.63
72 INT84596 Negative_regulation of Gene_expression of Aqp2 3 0.58 8.49 0.6
73 INT84594 Negative_regulation of Transcription of Aqp2 1 0.43 0 0.59
74 INT13929 Protein_catabolism of Th 3 1.00 0 0.58
75 INT314505 Positive_regulation of Protein_catabolism of TH 1 0.05 1.07 0.56
76 INT314499 Negative_regulation of Protein_catabolism of TH 1 0.04 1.06 0.54
77 INT18506 Negative_regulation of CD9 4 0.57 3.79 0.52
78 INT111304 Regulation of Gene_expression of TH 2 0.17 0.57 0.44
79 INT149235 Positive_regulation of Transcription of Aqp2 1 0.45 0.72 0.4
80 INT149244 Positive_regulation of Localization of Aqp2 1 0.49 0.72 0.4
81 INT314511 Positive_regulation of Binding of TH 1 0.04 0.68 0.38
82 INT157836 Regulation of Gene_expression of Aqp2 9 0.57 8.37 0.37
83 INT79558 Binding of Aqp2 2 0.31 0.25 0.33
84 INT83525 Negative_regulation of Transcription of Pnmt 3 0.57 0 0.27
85 INT51364 Localization of Slc14a2 6 0.31 0.1 0.26
86 INT40588 Regulation of Negative_regulation of Th 1 0.16 0.26 0.26
87 INT83526 Negative_regulation of Gene_expression of Pnmt 1 0.41 0 0.25
88 INT343976 Negative_regulation of Negative_regulation of TH 1 0.23 0.19 0.23
89 INT237448 Negative_regulation of Binding of TH 1 0.30 0.29 0.22
90 INT222191 Regulation of Gene_expression of CD9 1 0.07 0.38 0.19
91 INT140716 Negative_regulation of Protein_catabolism of Th 1 0.59 0 0.19
92 INT140717 Positive_regulation of Protein_catabolism of Th 1 0.47 0 0.19
93 INT222201 Positive_regulation of Gene_expression of CD9 1 0.18 0.37 0.19
94 INT16756 Regulation of Transcription of Pnmt 2 0.39 0.08 0.18
95 INT52998 Regulation of CD9 2 0.44 1.6 0.17
96 INT162939 Binding of Tfap2a 1 0.26 0.34 0.17
97 INT162940 Negative_regulation of Tfap2a 1 0.32 0.34 0.17
98 INT162941 Negative_regulation of Binding of Tfap2a 1 0.32 0.34 0.17
99 INT163586 Gene_expression of Slc14a2 1 0.07 0 0.16
100 INT31433 Binding of CD9 1 0.36 1.36 0.13
101 INT87567 Negative_regulation of Localization of Slc14a2 1 0.19 0 0.12
102 INT157832 Phosphorylation of Aqp2 2 0.77 2.04 0.08
103 INT66162 Positive_regulation of Binding of Pnmt 1 0.49 0 0.08
104 INT66164 Negative_regulation of Binding of Pnmt 1 0.41 0 0.08
105 INT66163 Binding of Pnmt 1 0.36 0 0.08
106 INT314508 Regulation of Positive_regulation of TH 1 0.04 0.92 0.08
107 INT293110 Positive_regulation of Phosphorylation of Aqp2 1 0.47 1.39 0.05
108 INT293105 Positive_regulation of Positive_regulation of Aqp2 1 0.47 0.72 0.03
109 INT157833 Negative_regulation of Negative_regulation of Aqp2 1 0.36 0 0
110 INT341042 Positive_regulation of Protein_catabolism of Aqp2 1 0.34 0.07 0
111 INT51365 Positive_regulation of Localization of Slc14a2 1 0.03 0 0
112 INT341039 Protein_catabolism of Aqp2 1 0.47 0.06 0
113 INT76171 Regulation of Regulation of Pnmt 1 0.19 0 0
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