GO:0009607

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Name response to biotic stimulus
Categary Process
Go Slim No
Go Link GO:0009607
Unique Molecular Interactions 45
Total Molecular Interactions 57
Total Single Events 718
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to biotic stimulus. They are ordered first by their pain relevance and then by number of times they were reported for response to biotic stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86518 Ass1 Positive_regulation of Hmox2 1 0.03 0.08 1.27
2 INT266742 GOPC Regulation of Positive_regulation of ACR 1 0.02 0.36 1.05
3 INT221034 IL10 Positive_regulation of Localization of CCL18 1 0.19 1.3 0.84
4 INT221033 TNF Positive_regulation of Gene_expression of CCL18 1 0.29 0.76 0.52
5 INT17622 Ass1 Positive_regulation of Lhb 1 0.02 1.22 0.49
6 INT239474 Binding of ACR and Ifx 1 0.02 0.36 0.45
7 INT221026 ELANE Positive_regulation of Gene_expression of CCL18 1 0.01 0.57 0.45
8 INT221024 TNF Negative_regulation of Gene_expression of CCL18 1 0.18 0.8 0.44
9 INT90079 Ass1 Positive_regulation of Casp1 1 0.02 0.99 0.43
10 INT187837 Ass1 Regulation of Mcpt1 1 0.00 1.29 0.37
11 INT319383 Binding of CCL18 and CCL22 1 0.19 1.07 0.25
12 INT221022 IL10 Positive_regulation of CCL18 1 0.19 0.38 0.22
13 INT221020 IL13 Positive_regulation of Gene_expression of CCL18 1 0.06 0.12 0.19
14 INT298787 Binding of PPARA and TUSC5 1 0.32 1.38 0.19
15 INT221017 IL4 Positive_regulation of Gene_expression of CCL18 1 0.05 0.13 0.19
16 INT221032 IL10 Positive_regulation of Gene_expression of CCL18 1 0.14 0.13 0.19
17 INT244230 Binding of IL8 and CCL18 1 0.02 0.23 0.17
18 INT244244 Binding of CCL18 and Cxcl1 1 0.04 0.23 0.17
19 INT221035 ELANE Positive_regulation of CCL18 1 0.01 0.24 0.15
20 INT298782 PPARA Positive_regulation of Gene_expression of TUSC5 1 0.42 0.62 0.15
21 INT304463 Ass1 Positive_regulation of P2rx4 1 0.01 0 0.14
22 INT237442 Ass1 Positive_regulation of S100b 1 0.00 0.18 0.13
23 INT310695 Binding of Btk and Pla2g6 1 0.18 0.16 0.12
24 INT298783 PPARA Positive_regulation of TUSC5 1 0.37 0.15 0.09
25 INT298781 Positive_regulation of PPARA Positive_regulation of TUSC5 1 0.37 0.15 0.09
26 INT304460 Ass1 Positive_regulation of Xist 1 0.00 0 0.09
27 INT322207 CCL18 Regulation of Gene_expression of COL7A1 1 0.07 0.88 0.09
28 INT221016 TNF Positive_regulation of CCL18 1 0.29 0.15 0.08
29 INT221028 Binding of TNF and Positive_regulation of CCL18 1 0.21 0.15 0.08
30 INT38206 Acr Negative_regulation of Txnrd1 1 0.20 0.08 0.08
31 INT75038 Ass1 Positive_regulation of Transcription of Ephx1 1 0.00 0.08 0.07
32 INT198079 Ass1 Positive_regulation of Gene_expression of Slc1a3 1 0.01 0 0.07
33 INT75037 Ass1 Positive_regulation of Ephx1 1 0.00 0.08 0.07
34 INT203849 Ass1 Positive_regulation of Casp3 1 0.00 0.71 0.07
35 INT322206 CCL18 Positive_regulation of Gene_expression of COL7A1 1 0.05 0.28 0.05
36 INT304457 Ass1 Positive_regulation of Transcription of P2rx4 1 0.01 0 0.05
37 INT285385 Ass1 Positive_regulation of Transcription of Cyp1a2 1 0.00 0.09 0.03
38 INT315034 Ass1 Positive_regulation of Cacna1f 1 0.00 0 0.03
39 INT176554 Ass1 Positive_regulation of Gene_expression of Spp1 1 0.01 1.26 0
40 INT202403 Ass1 Positive_regulation of Mapk14 1 0.01 0 0
41 INT176535 Ass1 Positive_regulation of Lepr 1 0.00 0 0
42 INT176555 Ass1 Positive_regulation of Spp1 1 0.01 0 0
43 INT202394 Ass1 Positive_regulation of Map3k3 1 0.01 0 0
44 INT240011 Ass1 Positive_regulation of Gene_expression of Nkx2-2 1 0.00 0 0
45 INT204491 Ass1 Positive_regulation of App 1 0.01 0.43 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to biotic stimulus. They are ordered first by their pain relevance and then by number of times they were reported in response to biotic stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117598 Regulation of ACR 118 0.26 41.25 48.01
2 INT163134 Gene_expression of ACR 78 0.65 30.39 38.48
3 INT139664 Gene_expression of CCL18 83 0.76 37.05 21.95
4 INT195226 Positive_regulation of ACR 23 0.26 7.85 12.62
5 INT6431 Positive_regulation of Ass1 36 0.24 8.08 10.43
6 INT146808 Positive_regulation of CCL18 25 0.69 11.98 5.71
7 INT266746 Binding of ACR 8 0.23 3.44 5.26
8 INT146807 Localization of CCL18 17 0.78 11.8 4.79
9 INT36237 Gene_expression of Ass1 11 0.24 2.31 4.38
10 INT221045 Positive_regulation of Gene_expression of CCL18 17 0.67 5.27 3.54
11 INT139660 Transcription of CCL18 13 0.70 7.12 3.05
12 INT211192 Localization of ACR 8 0.73 3.04 3.03
13 INT266745 Regulation of Gene_expression of ACR 6 0.10 1.53 2.87
14 INT38204 Gene_expression of Acr 4 0.66 4.23 2.85
15 INT298821 Gene_expression of TUSC5 1 0.77 32.53 2.76
16 INT71946 Negative_regulation of Ass1 7 0.41 1.9 2.68
17 INT194586 Negative_regulation of ACR 8 0.26 2.04 2.41
18 INT258404 Positive_regulation of Gene_expression of ACR 4 0.28 1.08 2.24
19 INT299751 Positive_regulation of Positive_regulation of ACR 1 0.05 0.78 1.59
20 INT221037 Positive_regulation of Localization of CCL18 5 0.67 7.7 1.44
21 INT221051 Regulation of Gene_expression of CCL18 6 0.60 1.99 1.25
22 INT194591 Negative_regulation of Gene_expression of ACR 2 0.07 0.33 1.23
23 INT221049 Positive_regulation of Transcription of CCL18 3 0.45 4.47 1.15
24 INT182369 Regulation of CCL18 2 0.60 2.92 1.13
25 INT245137 Transcription of Ass1 2 0.03 0.82 0.89
26 INT92337 Localization of Ass1 3 0.41 1.42 0.86
27 INT221048 Negative_regulation of Gene_expression of CCL18 1 0.57 1.38 0.81
28 INT298807 Positive_regulation of Gene_expression of TUSC5 1 0.69 6.08 0.64
29 INT221042 Regulation of Transcription of CCL18 3 0.60 0.84 0.62
30 INT221041 Binding of CCL18 3 0.47 2.08 0.59
31 INT298822 Positive_regulation of TUSC5 1 0.69 5.45 0.51
32 INT195228 Negative_regulation of Positive_regulation of ACR 1 0.10 0.82 0.49
33 INT159041 Negative_regulation of TUSC5 2 0.42 3.46 0.48
34 INT146811 Negative_regulation of CCL18 2 0.37 1.05 0.45
35 INT298808 Negative_regulation of Gene_expression of TUSC5 1 0.43 3.9 0.42
36 INT258403 Negative_regulation of Localization of ACR 1 0.24 0.92 0.38
37 INT298817 Transcription of TUSC5 1 0.68 1.87 0.37
38 INT258408 Positive_regulation of Regulation of ACR 1 0.26 0.07 0.36
39 INT221053 Negative_regulation of Localization of CCL18 1 0.41 0.59 0.29
40 INT298819 Binding of TUSC5 1 0.37 2.41 0.27
41 INT298812 Regulation of Gene_expression of TUSC5 1 0.61 2.97 0.23
42 INT345939 Negative_regulation of Regulation of ACR 1 0.01 0.52 0.18
43 INT298816 Localization of TUSC5 1 0.79 1.68 0.17
44 INT257835 Negative_regulation of Btk 6 0.41 2.41 0.16
45 INT298823 Negative_regulation of Transcription of TUSC5 1 0.42 0.78 0.14
46 INT245135 Regulation of Transcription of Ass1 1 0.02 0.25 0.13
47 INT185424 Binding of Ass1 2 0.36 1.66 0.12
48 INT104405 Positive_regulation of Acr 3 0.28 0.47 0.09
49 INT298814 Regulation of TUSC5 1 0.45 1.8 0.08
50 INT298824 Positive_regulation of Positive_regulation of TUSC5 1 0.50 0.54 0.08
51 INT298810 Negative_regulation of Positive_regulation of TUSC5 1 0.43 0.47 0.08
52 INT298826 Negative_regulation of Binding of TUSC5 1 0.42 0.71 0.08
53 INT221036 Positive_regulation of Positive_regulation of CCL18 1 0.49 0.08 0.07
54 INT298813 Positive_regulation of Transcription of TUSC5 1 0.50 0.41 0.04
55 INT355368 Regulation of Btk 1 0.01 0.39 0.04
56 INT315844 Binding of Btk 2 0.16 0.59 0.03
57 INT257834 Gene_expression of Btk 7 0.65 3.45 0
58 INT38205 Negative_regulation of Acr 3 0.50 0.1 0
59 INT130131 Regulation of Acr 2 0.11 0.2 0
60 INT179206 Binding of Acr 1 0.21 0 0
61 INT97888 Localization of Acr 1 0.11 0 0
62 INT317763 Regulation of Ass1 1 0.01 0.09 0
63 INT146809 Negative_regulation of Positive_regulation of CCL18 1 0.37 0.26 0
64 INT286540 Localization of Btk 1 0.28 1.26 0
65 INT315841 Protein_catabolism of Btk 1 0.12 0.29 0
66 INT331724 Protein_catabolism of Ass1 1 0.96 0.26 0
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