GO:0009611

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Name response to wounding
Categary Process
Go Slim No
Go Link GO:0009611
Unique Molecular Interactions 2196
Total Molecular Interactions 3032
Total Single Events 26861
Pain Genes Associated 98

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to wounding. They are ordered first by their pain relevance and then by number of times they were reported for response to wounding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
2 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
3 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
4 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52
5 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
6 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
7 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
8 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
9 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
10 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
11 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
12 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
13 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
14 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
15 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
16 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
17 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
18 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
19 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
20 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
21 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
22 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
23 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
24 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
25 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
26 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
27 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
28 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
29 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
30 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
31 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
32 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
33 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
34 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
35 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
36 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
37 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
38 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13
39 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
40 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
41 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
42 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
43 INT281381 FSCN1 Positive_regulation of Gene_expression of Gfap 1 0.06 1.13 1.98
44 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
45 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
46 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
47 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
48 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
49 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
50 INT134686 FSCN1 Positive_regulation of Gfap 1 0.00 0.71 1.89
51 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
52 INT352464 Gse1 Positive_regulation of Gene_expression of Slc1a3 1 0.05 1.55 1.83
53 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
54 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
55 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
56 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
57 INT157459 Binding of CX3CR1 and CX3CL1 1 0.32 2.12 1.7
58 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
59 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
60 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
61 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
62 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
63 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
64 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
65 INT130839 Gfap Positive_regulation of S100B 1 0.51 1.9 1.56
66 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
67 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56
68 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
69 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
70 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
71 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
72 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
73 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
74 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
75 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
76 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
77 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
78 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
79 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
80 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
81 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
82 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
83 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
84 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
85 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
86 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
87 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
88 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
89 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
90 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
91 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
92 INT351245 Binding of TNC and OPN1LW 1 0.03 0.89 1.31
93 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
94 INT158144 Binding of Gpx1 and Glyat 2 0.31 0 1.29
95 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
96 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
97 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
98 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27
99 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
100 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
101 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
102 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
103 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
104 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
105 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
106 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
107 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
108 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
109 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
110 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
111 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
112 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
113 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
114 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
115 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
116 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
117 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
118 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
119 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
120 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
121 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
122 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
123 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
124 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
125 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
126 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
127 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
128 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
129 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
130 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12
131 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
132 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
133 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
134 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
135 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
136 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
137 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
138 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09
139 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09
140 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
141 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
142 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
143 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
144 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
145 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
146 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
147 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
148 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05
149 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
150 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
151 INT76001 Ngf Positive_regulation of Ngfr 1 0.16 0.93 1.05
152 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
153 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
154 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04
155 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
156 INT297487 Negative_regulation of Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.46 1.03
157 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02
158 INT297486 Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.45 1.02
159 INT106706 POMC Negative_regulation of Binding of FN1 1 0.19 0.79 1.02
160 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01
161 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
162 INT180770 Gdnf Positive_regulation of Zbtb38 1 0.00 0.27 0.99
163 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
164 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98
165 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98
166 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
167 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
168 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
169 INT127672 Binding of NGFR and NTRK1 1 0.17 2.28 0.97
170 INT180780 Ngf Regulation of Gdnf 1 0.22 0.28 0.96
171 INT272984 Il6 Positive_regulation of Gene_expression of Itgam 1 0.24 0.78 0.96
172 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
173 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
174 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
175 INT180803 Sorbs1 Regulation of Gdnf 1 0.01 0.28 0.95
176 INT42482 Binding of Cpe and Pebp1 1 0.02 0 0.95
177 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
178 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
179 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
180 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
181 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92
182 INT129003 Ccl2 Positive_regulation of ANTXRL 1 0.00 0.68 0.92
183 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
184 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
185 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
186 INT147505 Binding of Ret and Gdnf 1 0.27 0.81 0.92
187 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92
188 INT138602 Negative_regulation of BCL2L2 Positive_regulation of F2 1 0.00 0.67 0.92
189 INT138601 BCL2L2 Positive_regulation of F2 1 0.00 0.66 0.91
190 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91
191 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
192 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
193 INT108647 Binding of Grin2a and Camk1d 1 0.33 0.78 0.9
194 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
195 INT91270 Oprd1 Regulation of Gene_expression of Il6 1 0.00 0 0.89
196 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
197 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
198 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
199 INT242621 Gdnf Positive_regulation of Gene_expression of Scn11a 1 0.05 0.12 0.88
200 INT91273 Mtr Positive_regulation of Localization of Il6 1 0.17 0 0.88

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to wounding. They are ordered first by their pain relevance and then by number of times they were reported in response to wounding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
2 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
3 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
4 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
5 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
6 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71
7 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
8 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
9 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
10 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84
11 INT5843 Positive_regulation of Gfap 184 0.70 108.2 70.21
12 INT19511 Localization of Il6 212 0.81 118.17 67.67
13 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
14 INT11937 Localization of Il6 228 0.81 139.83 64.39
15 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
16 INT10706 Regulation of Il6 150 0.62 93.23 62.34
17 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
18 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
19 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06
20 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31
21 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
22 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
23 INT74827 Positive_regulation of Gene_expression of Slc1a2 52 0.70 26.54 50.63
24 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
25 INT6864 Positive_regulation of Gene_expression of Gfap 110 0.70 59.01 47.07
26 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
27 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
28 INT127013 Negative_regulation of Slc1a3 37 0.54 14.16 43.97
29 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
30 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
31 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
32 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38
33 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37
34 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72
35 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
36 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
37 INT9655 Regulation of Il6 98 0.62 70.92 31.95
38 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49
39 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
40 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
41 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
42 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
43 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25
44 INT82882 Localization of Ccl2 61 0.80 41.96 28
45 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
46 INT77793 Positive_regulation of Gdnf 54 0.70 23.76 25.08
47 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
48 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03
49 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
50 INT49553 Regulation of Gene_expression of Gfap 42 0.62 17.04 23.65
51 INT6866 Regulation of Gfap 51 0.61 19.6 23.56
52 INT99539 Positive_regulation of Slc1a2 25 0.67 5.46 23.38
53 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
54 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7
55 INT12114 Positive_regulation of Tnfrsf1a 46 0.69 36.26 22.54
56 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
57 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
58 INT135673 Positive_regulation of Slc1a3 23 0.57 5.45 21.45
59 INT93485 Negative_regulation of Slc1a2 27 0.59 10.65 20.9
60 INT51474 Binding of Il6 55 0.48 44.99 20.52
61 INT49985 Transcription of Il6 62 0.72 40.13 20.29
62 INT48663 Negative_regulation of Gene_expression of Gfap 45 0.59 18.34 19.84
63 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8
64 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
65 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
66 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99
67 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
68 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
69 INT118512 Gene_expression of F2r 33 0.63 26.56 18.26
70 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
71 INT96532 Negative_regulation of Gene_expression of Slc1a2 24 0.59 14.22 17.91
72 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85
73 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
74 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
75 INT98110 Regulation of Gene_expression of Slc1a2 16 0.62 11.76 17.31
76 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07
77 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
78 INT139830 Gene_expression of AGER 47 0.75 41.71 16.53
79 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2
80 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
81 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13
82 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
83 INT98647 Positive_regulation of Mdk 65 0.59 32.93 15.67
84 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
85 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
86 INT49376 Negative_regulation of Localization of Il6 37 0.59 12.66 14.99
87 INT14647 Positive_regulation of Grin2a 26 0.67 4.69 14.8
88 INT107585 Gene_expression of CCR2 35 0.71 26.44 14.75
89 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
90 INT98109 Regulation of Slc1a3 15 0.52 6.87 14.43
91 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
92 INT59870 Gene_expression of F3 51 0.65 51.83 14.01
93 INT105156 Phosphorylation of Gfap 23 0.79 11.85 13.76
94 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
95 INT135674 Positive_regulation of Gene_expression of Slc1a3 11 0.62 5.21 13.61
96 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52
97 INT20066 Gene_expression of Mdk 38 0.76 21.41 13.4
98 INT102897 Positive_regulation of Gene_expression of Gdnf 34 0.69 11.13 13.28
99 INT20632 Gene_expression of TNC 72 0.78 30.43 13.16
100 INT54763 Binding of Il6 82 0.48 63.27 12.89
101 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
102 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
103 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
104 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
105 INT32054 Gene_expression of Tnc 14 0.59 9.36 12.22
106 INT100799 Negative_regulation of Grin2a 27 0.57 7.33 12.2
107 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
108 INT46695 Positive_regulation of TNC 28 0.67 17.06 12.04
109 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77
110 INT66038 Positive_regulation of Ngfr 32 0.69 26.07 11.75
111 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64
112 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
113 INT50933 Transcription of Il6 38 0.72 24.31 11.58
114 INT57187 Positive_regulation of Gfap 49 0.69 27.59 11.46
115 INT182574 Localization of Slc1a3 10 0.73 5.47 11.44
116 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
117 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
118 INT79981 Positive_regulation of Gene_expression of Gdnf 27 0.70 12.49 10.77
119 INT157466 Gene_expression of CX3CR1 14 0.76 20.6 10.76
120 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59
121 INT82950 Positive_regulation of Gdnf 36 0.51 11.72 10.5
122 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
123 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
124 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
125 INT85844 Regulation of Gdnf 18 0.50 11.08 10.43
126 INT5840 Transcription of Gfap 26 0.71 18.18 10.41
127 INT49129 Positive_regulation of GFAP 35 0.69 28.78 10.38
128 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35
129 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
130 INT64193 Regulation of Grin2a 19 0.54 2.98 10.31
131 INT74828 Regulation of Slc1a2 12 0.61 3.92 10.3
132 INT49555 Positive_regulation of Positive_regulation of Gfap 18 0.69 11.51 10.29
133 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
134 INT6867 Positive_regulation of Gene_expression of GFAP 22 0.67 13.46 9.75
135 INT106200 Binding of Ccl2 22 0.42 16.7 9.75
136 INT58986 Gene_expression of Clu 17 0.77 8.35 9.61
137 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
138 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
139 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45
140 INT140224 Localization of Ccl2 32 0.72 26.91 9.39
141 INT98111 Negative_regulation of Gdnf 12 0.59 10.85 9.29
142 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
143 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
144 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
145 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08
146 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
147 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83
148 INT3622 Regulation of CTSB 34 0.58 16.08 8.76
149 INT179753 Gene_expression of SLC1A2 28 0.59 13.72 8.71
150 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62
151 INT77795 Localization of Gdnf 26 0.81 6.29 8.55
152 INT2225 Binding of Gfap 31 0.47 11.78 8.53
153 INT77790 Positive_regulation of Gene_expression of Tnfrsf1a 16 0.67 15.88 8.5
154 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
155 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
156 INT15592 Positive_regulation of F2r 17 0.67 8.66 8.36
157 INT75921 Negative_regulation of Ngfr 13 0.59 8.58 8.35
158 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
159 INT44003 Gene_expression of F3 40 0.75 27.92 8.29
160 INT77794 Binding of Gdnf 15 0.48 8.38 8.22
161 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
162 INT48310 Binding of Ngfr 25 0.48 9.72 8.16
163 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15
164 INT117497 Positive_regulation of F2r 18 0.57 14.45 8.13
165 INT79166 Regulation of TNC 12 0.44 9.42 8.13
166 INT2271 Gene_expression of F2 51 0.76 30.21 7.97
167 INT92003 Positive_regulation of Transcription of Gdnf 10 0.66 5.54 7.84
168 INT98178 Localization of Casp3 32 0.65 21.01 7.77
169 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76
170 INT87546 Transcription of Gdnf 15 0.71 7.49 7.76
171 INT7168 Positive_regulation of Ctsb 9 0.70 0.3 7.58
172 INT79168 Binding of TNC 39 0.47 16.51 7.55
173 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51
174 INT61542 Positive_regulation of Ngfr 15 0.70 6.35 7.34
175 INT14732 Positive_regulation of FN1 46 0.69 31.17 7.33
176 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
177 INT184281 Binding of AGER 25 0.37 23.06 7.32
178 INT155680 Gene_expression of Slc1a3 22 0.66 6.76 7.23
179 INT6861 Negative_regulation of Gfap 32 0.58 13.71 7.22
180 INT85764 Binding of PEBP1 9 0.44 4.52 7.2
181 INT82881 Regulation of Ccl2 19 0.57 15.29 7.19
182 INT717 Regulation of F2 29 0.61 17.46 6.99
183 INT127014 Negative_regulation of Negative_regulation of Slc1a3 6 0.54 2.11 6.98
184 INT102814 Negative_regulation of CASP3 46 0.43 28.54 6.94
185 INT102749 Positive_regulation of Positive_regulation of CASP3 32 0.67 26.07 6.93
186 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
187 INT93144 Gene_expression of CCR1 18 0.75 14.69 6.84
188 INT245173 Gene_expression of MDK 81 0.49 51.08 6.78
189 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75
190 INT5839 Positive_regulation of Transcription of Gfap 10 0.49 11.61 6.74
191 INT78713 Negative_regulation of Ngfr 9 0.54 7.07 6.73
192 INT92001 Regulation of Gene_expression of Gdnf 12 0.62 6.62 6.65
193 INT157465 Positive_regulation of Gene_expression of CX3CR1 5 0.49 8.9 6.62
194 INT33781 Binding of Pebp1 11 0.44 1.76 6.61
195 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
196 INT108585 Positive_regulation of Gene_expression of CASP3 35 0.70 28.37 6.45
197 INT1280 Negative_regulation of Pebp1 7 0.28 2.12 6.45
198 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
199 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41
200 INT105157 Positive_regulation of Phosphorylation of Gfap 8 0.67 6.48 6.38
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