GO:0009612

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Name response to mechanical stimulus
Categary Process
Go Slim No
Go Link GO:0009612
Unique Molecular Interactions 3153
Total Molecular Interactions 4551
Total Single Events 48876
Pain Genes Associated 109

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to mechanical stimulus. They are ordered first by their pain relevance and then by number of times they were reported for response to mechanical stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
3 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
4 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
5 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
6 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
7 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
8 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
9 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
10 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
11 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
12 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
13 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
14 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
15 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81
16 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
17 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
18 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
19 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
20 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
21 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
22 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
23 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
24 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
25 INT354207 Igfbp7 Positive_regulation of Accn3 1 0.52 6.55 3.24
26 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
27 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
28 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
29 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
30 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
31 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
32 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
33 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
34 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
35 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
36 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
37 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
38 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
39 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
40 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
41 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
42 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
43 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62
44 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
45 INT67905 Binding of Spn and Fosl1 1 0.24 2.1 2.54
46 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
47 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
48 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46
49 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
50 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
51 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
52 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
53 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
54 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
55 INT108987 Ngf Regulation of Gene_expression of Sit1 1 0.00 1.46 2.32
56 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
57 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
58 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
59 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
60 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
61 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
62 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
63 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
64 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
65 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
66 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
67 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
68 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
69 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
70 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
71 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
72 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
73 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
74 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
75 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
76 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
77 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
78 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
79 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
80 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
81 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
82 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
83 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
84 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
85 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
86 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
87 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
88 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
89 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
90 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
91 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
92 INT14991 SFTPA1 Positive_regulation of Localization of MPO 1 0.11 1.65 1.92
93 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
94 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
95 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
96 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
97 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
98 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85
99 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
100 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
101 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
102 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
103 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
104 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
105 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
106 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
107 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
108 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
109 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73
110 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
111 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
112 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
113 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
114 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
115 INT80199 Ngf Regulation of Transcription of Rab38 1 0.01 1.48 1.68
116 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
117 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
118 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
119 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
120 INT354210 Binding of Igfbp7 and Accn3 1 0.27 3.91 1.64
121 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
122 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
123 INT266768 NGF Positive_regulation of Localization of SFTPA1 1 0.01 1.65 1.6
124 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
125 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
126 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
127 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
128 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
129 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
130 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
131 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
132 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
133 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54
134 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54
135 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
136 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
137 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
138 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
139 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
140 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48
141 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
142 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
143 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
144 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
145 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
146 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
147 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
148 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
149 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43
150 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
151 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
152 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
153 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
154 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
155 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4
156 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
157 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
158 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
159 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
160 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
161 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
162 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
163 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
164 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
165 INT60992 Ngf Regulation of CRTAC1 1 0.00 0 1.35
166 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35
167 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
168 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
169 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34
170 INT140531 Ngf Positive_regulation of DYT10 1 0.72 1.83 1.34
171 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
172 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
173 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
174 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
175 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
176 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
177 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
178 INT181492 NGF Regulation of TRPV1 1 0.21 0.93 1.31
179 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 0.01 0.81 1.31
180 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
181 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29
182 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
183 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
184 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
185 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
186 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
187 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
188 INT149844 Negative_regulation of Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.26
189 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
190 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
191 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
192 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
193 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
194 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
195 INT149845 Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.24
196 INT71443 CSAD Positive_regulation of Gene_expression of Fos 1 0.58 0.81 1.23
197 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
198 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
199 INT147033 Positive_regulation of Binding of Sds and Accn3 1 0.13 0.73 1.23
200 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to mechanical stimulus. They are ordered first by their pain relevance and then by number of times they were reported in response to mechanical stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
3 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
4 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
5 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
6 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
7 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
8 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
9 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
10 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
11 INT6852 Localization of TNF 883 0.81 705.95 270.84
12 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
13 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
14 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
15 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
16 INT6481 Binding of TNF 624 0.48 510.2 214.82
17 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
18 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
19 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
20 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
21 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
22 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
23 INT9660 Regulation of TNF 363 0.62 312.94 139.99
24 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
25 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
26 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
27 INT12082 Localization of IL6 365 0.81 241.78 105.78
28 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
29 INT5587 Regulation of Fos 191 0.62 40.81 99.7
30 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
31 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
32 INT10166 Localization of Tnf 237 0.81 153.95 88.64
33 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
34 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
35 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
36 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47
37 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
38 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
39 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
40 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
41 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
42 INT3034 Localization of Ngf 126 0.81 50.81 72.84
43 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
44 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
45 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
46 INT19511 Localization of Il6 212 0.81 118.17 67.67
47 INT10706 Regulation of Il6 150 0.62 93.23 62.34
48 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
49 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
50 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
51 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
52 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
53 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
54 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
55 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
56 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
57 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
58 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
59 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
60 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
61 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
62 INT9210 Regulation of IL6 166 0.62 125.61 49.95
63 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
64 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
65 INT19078 Binding of Ngf 78 0.48 31.03 44.33
66 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
67 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
68 INT13354 Transcription of TNF 108 0.72 85.81 42.32
69 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
70 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57
71 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
72 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
73 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
74 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
75 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
76 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
77 INT21527 Gene_expression of FosB 47 0.78 11.2 34.39
78 INT65698 Localization of CCL2 118 0.81 77.54 32.69
79 INT99610 Localization of MMP9 126 0.79 48.46 32.67
80 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
81 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
82 INT6053 Transcription of Fos 107 0.72 20.97 31.88
83 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
84 INT47764 Binding of Jun 106 0.48 22.62 31.39
85 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16
86 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
87 INT6058 Localization of Fos 73 0.81 16.7 30.84
88 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11
89 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
90 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
91 INT86437 Binding of IL6 154 0.48 121.22 29.3
92 INT53384 Positive_regulation of FosB 41 0.69 8.43 28.91
93 INT98522 Gene_expression of Accn3 68 0.78 26.95 28.6
94 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
95 INT116737 Localization of Mif 63 0.81 52.97 28.11
96 INT82882 Localization of Ccl2 61 0.80 41.96 28
97 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
98 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98
99 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
100 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
101 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42
102 INT53385 Positive_regulation of Gene_expression of FosB 26 0.70 9.18 26.33
103 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95
104 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
105 INT5199 Gene_expression of Fosl1 44 0.78 8.66 24.8
106 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
107 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01
108 INT100124 Gene_expression of Accn3 38 0.78 30.02 23.63
109 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
110 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38
111 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
112 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05
113 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
114 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
115 INT5586 Binding of Fos 47 0.48 12.7 21.33
116 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
117 INT51474 Binding of Il6 55 0.48 44.99 20.52
118 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
119 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
120 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03
121 INT64261 Negative_regulation of Positive_regulation of Ngf 21 0.59 16.28 19.78
122 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
123 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
124 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
125 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
126 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
127 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
128 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
129 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
130 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
131 INT61626 Transcription of IL6 73 0.72 42.04 17.86
132 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71
133 INT49922 Positive_regulation of Positive_regulation of Ngf 21 0.67 14.46 17.68
134 INT15358 Transcription of Ngf 29 0.72 10.43 16.94
135 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
136 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
137 INT61949 Regulation of Nos2 74 0.58 34.08 16.7
138 INT20216 Localization of NGF 40 0.80 18.16 16.61
139 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
140 INT84924 Positive_regulation of Gene_expression of NGF 29 0.68 17.91 16.46
141 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
142 INT48540 Gene_expression of Kcna5 37 0.77 14.04 16.07
143 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
144 INT75434 Gene_expression of Il13 27 0.52 26.19 15.4
145 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
146 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
147 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
148 INT71150 Binding of NGF 22 0.46 13.67 14.81
149 INT5904 Localization of MPO 62 0.81 36.37 14.64
150 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
151 INT17593 Regulation of Jun 37 0.60 5.5 14.35
152 INT10173 Binding of Tnf 45 0.48 35.6 14.32
153 INT115071 Positive_regulation of Accn3 14 0.70 16.56 14.24
154 INT59870 Gene_expression of F3 51 0.65 51.83 14.01
155 INT91544 Gene_expression of CHI3L1 60 0.75 77.72 13.9
156 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
157 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
158 INT69166 Positive_regulation of P2ry1 35 0.67 8.41 13.63
159 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
160 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52
161 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
162 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
163 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
164 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
165 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99
166 INT15246 Regulation of FOS 32 0.60 15.34 12.94
167 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
168 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
169 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
170 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
171 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
172 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
173 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45
174 INT10433 Positive_regulation of Junb 35 0.70 6.55 12.42
175 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
176 INT32054 Gene_expression of Tnc 14 0.59 9.36 12.22
177 INT4460 Regulation of Mpo 44 0.62 31.16 12.11
178 INT9483 Gene_expression of Junb 34 0.78 3.24 12.08
179 INT5649 Negative_regulation of Positive_regulation of Mpo 31 0.59 26.62 11.92
180 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9
181 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
182 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
183 INT72949 Binding of Mif 31 0.46 23.12 11.65
184 INT50933 Transcription of Il6 38 0.72 24.31 11.58
185 INT6051 Positive_regulation of Transcription of Fos 27 0.69 6.3 11.48
186 INT93122 Gene_expression of P2ry1 32 0.75 11.82 11.42
187 INT7903 Positive_regulation of Fosl1 21 0.70 3.53 11.36
188 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
189 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28
190 INT68290 Gene_expression of Accn1 32 0.73 7.36 11.23
191 INT52233 Transcription of Jun 37 0.66 6.39 11.15
192 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15
193 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
194 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81
195 INT65627 Negative_regulation of Kcna5 19 0.59 7.82 10.79
196 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76
197 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
198 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
199 INT52657 Phosphorylation of Fos 20 0.80 6.36 10.64
200 INT85048 Regulation of NGF 19 0.62 11.61 10.5
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